A controlled release of antibiotics from calcium phosphate-coated poly(lactic-co-glycolic acid) particles and their in vitro efficacy against Staphylococcus aureus biofilm

Journal of Materials Science: Materials in Medicine

Volumn 25, Issue 3, 2014, Pages 747-757

  Bastari, Kelsen ^a   Arshath, Mohamed ^a   Ng, Zhi Hui Melissa ^a   Chia, Jia Hua ^a   Yow, Zhi Xian Daniel ^b   Sana, Barindra ^c   Tan, Meng Fong Cherine ^b   Lim, Sierin ^c   Loo, Say Chye Joachim ^a,d  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^b SCHOOL OF ENGINEERING   (Singapore)

^c Nanyang Technological University   (Singapore)

^d NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTICS; BACTERIA; BIOFILMS; CALCIUM PHOSPHATE; COATINGS; COPOLYMERS; EMULSIFICATION; ENERGY DISPERSIVE SPECTROSCOPY; HYBRID SYSTEMS; PHOTOELECTRONS; SCANNING ELECTRON MICROSCOPY; X RAY PHOTOELECTRON SPECTROSCOPY;

BIOFILM FORMATION; CONTROLLED RELEASE; EMULSION SOLVENT EVAPORATION; ENERGY DISPERSIVE X-RAY SPECTROSCOPY; HYBRID PARTICLES; POLY LACTIC-CO-GLYCOLIC ACID; STAPHYLOCOCCUS AUREUS; SUSTAINED RELEASE;

ENZYME INHIBITION;

ANTIBIOTIC AGENT; CALCIUM PHOSPHATE CERAMIC; LEVOFLOXACIN; NAFCILLIN; POLYGLACTIN; POLYMER; SOLVENT;

ANTIBIOTIC THERAPY; ARTICLE; BIODEGRADABILITY; BIOFILM; CONTROLLED DRUG RELEASE; DRUG DELIVERY SYSTEM; DRUG EFFICACY; EMULSION; ENERGY DISPERSIVE X RAY SPECTROSCOPY; IN VITRO STUDY; MATERIAL COATING; NONHUMAN; OSTEOMYELITIS; PRIORITY JOURNAL; ROENTGEN SPECTROSCOPY; SCANNING ELECTRON MICROSCOPY; STAPHYLOCOCCUS AUREUS; SUSTAINED DRUG RELEASE; X RAY PHOTOELECTRON SPECTROSCOPY;

BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS AUREUS;

ANTI-BACTERIAL AGENTS; BIOFILMS; CALCIUM PHOSPHATES; CELL SURVIVAL; DELAYED-ACTION PREPARATIONS; DIFFUSION; NANOCAPSULES; PARTICLE SIZE; POLYGLYCOLIC ACID; STAPHYLOCOCCUS AUREUS;

EID: 84896545550     PISSN: 09574530     EISSN: 15734838     Source Type: Journal    
DOI: 10.1007/s10856-013-5125-9     Document Type: Article

References (43)

1. Di Silvio L, Bonfield W. Biodegradable drug delivery system for the treatment of bone infection and repair. J Mater Sci. 1999;10:653-8.
2. Liu HN, Webster TJ. Ceramic/polymer nanocomposites with tunable drug delivery capability at specific disease sites. J Biomed Mater Res A. 2009;93A:1180-92.
3. Nandi SK, Mukherjee P, Roy S, Kundu B, De DK, Basu D. Local antibiotic delivery systems for the treatment of osteomyelitis - a review. Mater Sci Eng C. 2009;29:2478-85.
4. Naraharisetti PK, Lew MDN, Fu YC, Lee DJ, Wang CH. Gentamicin-loaded discs and microspheres and their modifications: characterization and in vitro release. J Control Release. 2005;102:345-59.
5. Billon A, Chabaud L, Gouyette A, Bouler JM, Merle C. Vancomycin biodegradable poly(lactide-co-glycolide) microparticles for bone implantation. Influence of the formulation parameters on the size, morphology, drug loading and in vitro release. J Microencapsul. 2005;22:841-52.
6. Xu QG, Czemuszka JI. Controlled release of amoxicillin from hydroxyapatite-coated poly(lactic-co-glycolic acid) microspheres. J Control Release. 2008;127:146-53.
7. Schnieders J, Gbureck U, Thull R, Kissel T. Controlled release of gentamicin from calcium phosphate - poly(lactic acid-co-glycolic acid) composite bone cement. Biomaterials. 2006;27:4239-49.
8. Kanellakopoulou K, Thivaios GC, Kolia M, Dontas I, Nakopoulou L, Dounis E, et al. Local treatment of experimental Pseudomonas aeruginosa osteomyelitis with a biodegradable dilactide polymer releasing ciprofloxacin. Antimicrob Agents Chemother. 2008;52:2335-9.
9. Jain AK, Panchagnula R. Skeletal drug delivery systems. Int J Pharm. 2000;206:1-12.
10. Glowka E, Sapin-Minet A, Leroy P, Lulek J, Maincent P. Preparation and in vitro-in vivo evaluation of salmon calcitonin-loaded polymeric nanoparticles. J Microencapsul. 2010;27:25-36.
11. Li Y, Lim S, Ooi C. Fabrication of cisplatin-loaded poly(lactide-co- glycolide) composite microspheres for osteosarcoma treatment. Pharm Res. 2012;29:756-69.
12. Rhee SH, Lee SJ. Effect of acidic degradation products of poly(lactic-co-glycolic)acid on the apatite-forming ability of poly(lactic-co-glycolic)acid-siloxane nanohybrid material. J Biomed Mater Res A. 2007;83A:799-805.
13. Kang SW, Yang HS, Seo SW, Han DK, Kim BS. Apatite-coated poly(lactic-co-glycolic acid) microspheres as an injectable scaffold for bone tissue engineering. J Biomed Mater Res A. 2008;85A:747-56.
14. Loo SCJ, Moore T, Banik B, Alexis F. Biomedical applications of hydroxyapatite nanoparticles. Curr Pharm Biotechnol. 2010;11:333-42.
15. Suzuki O. Interface of synthetic inorganic biomaterials and bone regeneration. Int Congr Ser. 2005;1284:274-83.
16. Joosten U, Joist A, Gosheger G, Liljenqvist U, Brandt B, von Eiff C. Effectiveness of hydroxyapatite-vancomycin bone cement in the treatment of Staphylococcus aureus induced chronic osteomyelitis. Biomaterials. 2005;26:5251-8.
17. Herrmann M, Vaudaux PE, Pittet D, Auckenthaler R, Lew PD, Perdreau FS, et al. Fibronectin, fibrinogen, and laminin act as mediators of adherence of clinical staphylococcal isolates to foreign material. J Infect Dis. 1988;158:693-701.
18. Lucke M, Schmidmaier G, Sadoni S, Wildemann B, Schiller R, Stemberger A, et al. A new model of implant-related osteomyelitis in rats. J Biomed Mater Res B. 2003;67B:593-602.
19. Davis JS. Management of bone and joint infections due to Staphylococcus aureus. Internal Med. 2005;35:S79-96.
20. Lee WL, Loei C, Widjaja E, Loo SCJ. Altering the drug release profiles of double-layered ternary-phase microparticles. J Control Release. 2011;151:229-38.
21. Lee WL, Yu P-O, Hong M, Widjaja E, Loo SCJ. Designing multilayered particulate systems for tunable drug release profiles. Acta Biomater. 2012;8:2271-8.
22. French GL. Staphylococcal sepsis: treatment ELS. New York: Wiley; 2001.
23. Lew DP, Waldvogel FA. Osteomyelitis. N Engl J Med. 1997;336:999-1007.
24. Croom KF, Goa KL. Levofloxacin: a review of its use in the treatment of bacterial infections in the United States. Drugs. 2003;63:2769-802.
25. Koort JK, Makinen TJ, Suokas E, Veiranto M, Jalava J, Knuuti J, et al. Efficacy of ciprofloxacin-releasing bioabsorbable osteoconductive bone defect filler for treatment of experimental osteomyelitis due to Staphylococcus aureus. Antimicrob Agents Chemother. 2005;49:1502-8.
26. Virto MR, Elorza B, Torrado S, Elorza MDA, Frutos G. Improvement of gentamicin poly(d, l-lactic-co-glycolic acid) microspheres for treatment of osteomyelitis induced by orthopedic procedures. Biomaterials. 2007;28:877-85.
27. Wimer SM, Schoonover L, Garrison MW. Levofloxacin: a therapeutic review. Clin Ther. 1998;20:1049-70.
28. Wiegand I, Hilpert K, Hancock REW. Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances. Nat Protocols. 2008;3:163-75.
29. Neut D, Kluin OS, Crielaard BJ, van der Mei HC, Busscher HJ, Grijpma DW. A biodegradable antibiotic delivery system based on poly-(trimethylene carbonate) for the treatment of osteomyelitis. Acta Orthopedica. 2009;80(5):514-9.
30. Kwasny SM, Opperman TJ. Static biofilm cultures of gram-positive pathogens grown in a microtiter format used for anti-biofilm drug discovery. Current Protocols in Pharmacology. New York: Wiley; 2001.
31. Shalaby S, Marc S. Polymeric controlled release systems for management of bone infection. Polymers for Dental and Orthopedic Applications. Boca Raton: CRC Press; 2006. p. 391-411.
32. Ito F, Fujimori H, Makino K. Factors affecting the loading efficiency of water-soluble drugs in PLGA microspheres. Colloids Surf B. 2008;61:25-9.
33. Xu Q, Crossley A, Czernuszka J. Preparation and characterization of negatively charged poly(lactic-co-glycolic acid) microspheres. J Pharm Sci. 2009;98:2377-89.
34. Astete CE, Sabliov CM. Synthesis and characterization of PLGA nanoparticles. J Biomater Sci. 2006;17:247-89.
35. Choi S-W, Zhang Y, Xia Y. Fabrication of microbeads with a controllable hollow interior and porous wall using a capillary fluidic device. Adv Funct Mater. 2009;19:2943-9.
36. Chaisri W, Ghassemi AH, Hennink WE, Okonogi S. Enhanced gentamicin loading and release of PLGA and PLHMGA microspheres by varying the formulation parameters. Colloids Surf B. 2011;84:508-14.
37. Frick A, Möller H, Wirbitzki E. Biopharmaceutical characterization of oral immediate release drug products. In vitro/in vivo comparison of phenoxymethylpenicillin potassium, glimepiride and levofloxacin. Eur J Pharm Biopharm. 1998;46:305-11.
38. Lee ES, Kwon MJ, Lee H, Kim JJ. Stabilization of protein encapsulated in poly(lactide-co-glycolide) microspheres by novel viscous S/W/O/W method. Int J Pharm. 2007;331:27-37.
39. Wischke C, Schwendeman SP. Principles of encapsulating hydrophobic drugs in PLA/PLGA microparticles. Int J Pharm. 2008;364:298-327.
40. Jongpaiboonkit L, Franklin-Ford T, Murphy WL. Growth of hydroxyapatite coatings on biodegradable polymer microspheres. ACS Appl Mater Interfaces. 2009;1:1504-11.
41. Taguchi T, Muraoka Y, Matsuyama H, Kishida A, Akashi M. Apatite coating on hydrophilic polymer-grafted poly(ethylene) films using an alternate soaking process. Biomaterials. 2001;22:53-8.
42. Fujihara K, Kotaki M, Ramakrishna S. Guided bone regeneration membrane made of polycaprolactone/calcium carbonate composite nano-fibers. Biomaterials. 2005;26:4139-47.
43. Boutinguiza M, Pou J, Lusquiños F, Comesaña R, Riveiro A. Laser-assisted production of tricalcium phosphate nanoparticles from biological and synthetic hydroxyapatite in aqueous medium. Appl Surf Sci. 2011;257:5195-9.