Vancomycin biodegradable poly(lactide-co-glycolide) microparticles for bone implantation. Influence of the formulation parameters on the size, morphology, drug loading and in vitro release

Journal of Microencapsulation

Volumn 22, Issue 8, 2005, Pages 841-852

  Billon, Aurélie ^a   Chabaud, L ^a   Gouyette, A ^a   Bouler, J M ^a   Merle, C ^a  

^a UNIVERSITÉ DE NANTES   (France)

Author keywords

Biodegradable microparticles; Controlled drug release; Poly(lactide co glycolide); Solvent evaporation extraction; Vancomycin

Indexed keywords

CALCIUM PHOSPHATE; POLYGLACTIN; SODIUM CHLORIDE; SURFACTANT; VANCOMYCIN;

AQUEOUS SOLUTION; ARTICLE; BIODEGRADABILITY; CHEMICAL PROCEDURES; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; EMULSION; IMPLANT; IN VITRO STUDY; MICROENCAPSULATION; PARTICLE SIZE; SCANNING ELECTRON MICROSCOPY; STRUCTURE ANALYSIS; ULTRAVIOLET SPECTROPHOTOMETRY;

ANTI-BACTERIAL AGENTS; BIOCOMPATIBLE MATERIALS; BIODEGRADATION, ENVIRONMENTAL; BONE TRANSPLANTATION; DELAYED-ACTION PREPARATIONS; DRUG COMPOUNDING; DRUG STABILITY; HUMANS; MICROSCOPY, ELECTRON, SCANNING; MICROSPHERES; PARTICLE SIZE; POLYGLACTIN 910; SODIUM CHLORIDE; SURFACE PROPERTIES; VANCOMYCIN;

EID: 31544455022     PISSN: 02652048     EISSN: 14645246     Source Type: Journal    
DOI: 10.1080/02652040500162790     Document Type: Article

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