Association between transforming growth factor beta-1 +869T/C polymorphism and acute rejection of solid organ allograft: A meta-analysis and systematic review

Transplant Immunology

Volumn 30, Issue 2-3, 2014, Pages 76-83

  Ge, Yu Zheng ^a   Yu, Peng ^a   Jia, Rui Peng ^a   Wu, Ran ^a   Ding, Ai Xing ^a   Li, Liang Peng ^a   Zhao, Yan ^a   Feng, Yu Ming ^a   Gui, Zan Long ^a   Liao, Sheng ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Acute rejection; Meta analysis; Polymorphisms; Transforming growth factor beta 1

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN A; LYMPHOCYTE ANTIBODY; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; RAPAMYCIN; STEROID; TACROLIMUS; TRANSFORMING GROWTH FACTOR BETA1; TGFB1 PROTEIN, HUMAN;

ACUTE GRAFT REJECTION; ARTICLE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; GRAFT RECIPIENT; HEART TRANSPLANTATION; HETEROZYGOTE; HIGH RISK POPULATION; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY TRANSPLANTATION; LIVER TRANSPLANTATION; ORGAN TRANSPLANTATION; PRIORITY JOURNAL; SYSTEMATIC REVIEW; TGFB1 GENE; ACUTE DISEASE; FEMALE; GENETICS; GRAFT REJECTION; MALE; MEDLINE; META ANALYSIS;

ACUTE DISEASE; FEMALE; GRAFT REJECTION; HUMANS; MALE; ORGAN TRANSPLANTATION; POLYMORPHISM, GENETIC; PUBMED; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84896542521     PISSN: 09663274     EISSN: 18785492     Source Type: Journal    
DOI: 10.1016/j.trim.2014.01.001     Document Type: Article

References (59)

1. Thurairajah P.H., Carbone M., Bridgestock H., Thomas P., Hebbar S., Gunson B.K., et al. Late acute liver allograft rejection; a study of its natural history and graft survival in the current era. Transplantation 2013, 95:955-959.
2. Chhabra D., Skaro A.I., Leventhal J.R., Dalal P., Shah G., Wang E., et al. Long-term kidney allograft function and survival in prednisone-free regimens: tacrolimus/mycophenolate mofetil versus tacrolimus/sirolimus. Clin J Am Soc Nephrol 2012, 7:504-512.
3. Stehlik J., Edwards L.B., Kucheryavaya A.Y., Benden C., Christie J.D., Dipchand A.I., et al. The Registry of the International Society for Heart and Lung Transplantation: 29th official adult heart transplant report - 2012. J Heart Lung Transplant 2012, 31:1052-1064.
4. Ponticelli C. The mechanisms of acute transplant rejection revisited. J Nephrol 2012, 25:150-158.
5. Sanchez-Fueyo A., Strom T.B. Immunologic basis of graft rejection and tolerance following transplantation of liver or other solid organs. Gastroenterology 2011, 140:51-64.
6. Hutchinson I.V. The role of transforming growth factor-beta in transplant rejection. Transplant Proc 1999, 31:9S-13S.
7. Morris-Stiff G. TGFbeta-1 and the development of chronic graft nephropathy: relative roles of gene, mRNA and protein. Ann R Coll Surg Engl 2005, 87:326-330.
8. Blobe G.C., Schiemann W.P., Lodish H.F. Role of transforming growth factor beta in human disease. N Engl J Med 2000, 342:1350-1358.
9. Pribylova-Hribova P., Kotsch K., Lodererova A., Viklicky O., Vitko S., Volk H.D., et al. TGF-beta1 mRNA upregulation influences chronic renal allograft dysfunction. Kidney Int 2006, 69:1872-1879.
10. Benza R.L., Coffey C.S., Pekarek D.M., Barchue J.P., Tallaj J.A., Passineau M.J., et al. Transforming growth factor-beta polymorphisms and cardiac allograft rejection. J Heart Lung Transplant 2009, 28:1057-1062.
11. Tambur A.R., Ortegel J.W., Ben-Ari Z., Shabtai E., Klein T., Michowiz R., et al. Role of cytokine gene polymorphism in hepatitis C recurrence and allograft rejection among liver transplant recipients. Transplantation 2001, 71:1475-1480.
12. Shah R., Rahaman B., Hurley C.K., Posch P.E. Allelic diversity in the TGFB1 regulatory region: characterization of novel functional single nucleotide polymorphisms. Hum Genet 2006, 119:61-74.
13. Densem C.G., Hutchinson I.V., Yonan N., Brooks N.H. Donor and recipient-transforming growth factor-beta 1 polymorphism and cardiac transplant-related coronary artery disease. Transpl Immunol 2004, 13:211-217.
14. Park J.Y., Park M.H., Park H., Ha J., Kim S.J., Ahn C. TNF-alpha and TGF-beta1 gene polymorphisms and renal allograft rejection in Koreans. Tissue Antigens 2004, 64:660-666.
15. Bathgate A.J., Pravica V., Perrey C., Therapondos G., Plevris J.N., Hayes P.C., et al. The effect of polymorphisms in tumor necrosis factor-alpha, interleukin-10, and transforming growth factor-beta1 genes in acute hepatic allograft rejection. Transplantation 2000, 69:1514-1517.
16. Marshall S.E., McLaren A.J., Haldar N.A., Bunce M., Morris P.J., Welsh K.I. The impact of recipient cytokine genotype on acute rejection after renal transplantation. Transplantation 2000, 70:1485-1491.
17. Jonsson J.R., Hong C., Purdie D.M., Hawley C., Isbel N., Butler M., et al. Role of cytokine gene polymorphisms in acute rejection and renal impairment after liver transplantation. Liver Transpl 2001, 7:255-263.
18. Marshall S.E., McLaren A.J., McKinney E.F., Bird T.G., Haldar N.A., Bunce M., et al. Donor cytokine genotype influences the development of acute rejection after renal transplantation. Transplantation 2001, 71:469-476.
19. Warle M.C., Farhan A., Metselaar H.J., Hop W.C., Perrey C., Zondervan P.E., et al. Cytokine gene polymorphisms and acute human liver graft rejection. Liver Transpl 2002, 8:603-611.
20. Bijlsma F.J., van der Horst A.A., Tilanus M.G., Rozemuller E., de Jonge N., Gmelig-Meyling F.H., et al. No association between transforming growth factor beta gene polymorphism and acute allograft rejection after cardiac transplantation. Transpl Immunol 2002, 10:43-47.
21. Hoffmann S., Park J., Jacobson L.M., Muehrer R.J., Lorentzen D., Kleiner D., et al. Donor genomics influence graft events: the effect of donor polymorphisms on acute rejection and chronic allograft nephropathy. Kidney Int 2004, 66:1686-1693.
22. Gourley I.S., Denofrio D., Rand W., Desai S., Loh E., Kamoun M. The effect of recipient cytokine gene polymorphism on cardiac transplantation outcome. Hum Immunol 2004, 65:248-254.
23. Karasu Z., Ulukaya S., Ayanoglu H.O., Basturk B., Ulukaya E., Akyildiz M., et al. Cytokine gene polymorphism and early graft rejection in liver transplant recipients. Transplant Proc 2004, 36:2791-2795.
24. Alakulppi N.S., Kyllonen L.E., Jantti V.T., Matinlauri I.H., Partanen J., Salmela K.T., et al. Cytokine gene polymorphisms and risks of acute rejection and delayed graft function after kidney transplantation. Transplantation 2004, 78:1422-1428.
25. Ligeiro D., Sancho M.R., Papoila A., Barradinhas A.M., Almeida A., Calao S., et al. Impact of donor and recipient cytokine genotypes on renal allograft outcome. Transplant Proc 2004, 36:827-829.
26. Mas V.R., Fisher R.A., Maluf D.G., Archer K.J., Contos M.J., Mills S.A., et al. Polymorphisms in cytokines and growth factor genes and their association with acute rejection and recurrence of hepatitis C virus disease in liver transplantation. Clin Genet 2004, 65:191-201.
27. Dmitrienko S., Hoar D.I., Balshaw R., Keown P.A. Immune response gene polymorphisms in renal transplant recipients. Transplantation 2005, 80:1773-1782.
28. Guo Y.F., Tan J.M., Li R.Y., Liu S.Z., Li Y., Ying K., et al. Impacts of donor and recipient's SNP of cytokine and cytokine receptor on early acute renal allograft rejection. Zhonghua Yi Xue Za Zhi 2005, 85:3126-3133.
29. Chow K.M., Szeto C.C., Poon P., Lau W.Y., Lai F.M., Li P.K. Transforming growth factor-beta1 gene polymorphism in renal transplant recipients. Ren Fail 2005, 27:671-675.
30. Di Filippo S., Zeevi A., McDade K.K., Bastien O., Webber S.A. Impact of TGFbeta1 gene polymorphisms on acute and chronic rejection in pediatric heart transplant allografts. Transplantation 2006, 81:934-939.
31. Gendzekhadze K., Rivas-Vetencourt P., Montano R.F. Risk of adverse post-transplant events after kidney allograft transplantation as predicted by CTLA-4 +49 and TNF-alpha -308 single nucleotide polymorphisms: a preliminary study. Transpl Immunol 2006, 16:194-199.
32. Gomez-Mateo J., Marin L., Lopez-Alvarez M.R., Moya-Quiles M.R., Miras M., Marin-Moreno I., et al. TGF-beta1 gene polymorphism in liver graft recipients. Transpl Immunol 2006, 17:55-57.
33. Hueso M., Navarro E., Moreso F., Beltran-Sastre V., Ventura F., Grinyo J.M., et al. Relationship between subclinical rejection and genotype, renal messenger RNA, and plasma protein transforming growth factor-beta1 levels. Transplantation 2006, 81:1463-1466.
34. Canossi A., Piazza A., Poggi E., Ozzella G., Di Rocco M., Papola F., et al. Renal allograft immune response is influenced by patient and donor cytokine genotypes. Transplant Proc 2007, 39:1805-1812.
35. Brabcova I., Petrasek J., Hribova P., Hyklova K., Bartosova K., Lacha J., et al. Genetic variability of major inflammatory mediators has no impact on the outcome of kidney transplantation. Transplantation 2007, 84:1037-1044.
36. Grinyo J., Vanrenterghem Y., Nashan B., Vincenti F., Ekberg H., Lindpaintner K., et al. Association of four DNA polymorphisms with acute rejection after kidney transplantation. Transpl Int 2008, 21:879-891.
37. Mendoza-Carrera F., Ojeda-Duran S., Angulo E., Rivas F., Macias-Lopez G., Buen E.P., et al. Influence of cytokine and intercellular adhesion molecule-1 gene polymorphisms on acute rejection in pediatric renal transplantation. Pediatr Transplant 2008, 12:755-761.
38. Manchanda P.K., Mittal R.D. Analysis of cytokine gene polymorphisms in recipient's matched with living donors on acute rejection after renal transplantation. Mol Cell Biochem 2008, 311:57-65.
39. Xie H.Y., Wang W.L., Yao M.Y., Yu S.F., Feng X.N., Jin J., et al. Polymorphisms in cytokine genes and their association with acute rejection and recurrence of hepatitis B in Chinese liver transplant recipients. Arch Med Res 2008, 39:420-428.
40. Yang J.P., Zheng J.H., Min Z.L. Donor cytokine gene polymorphisms affect the development of acute rejection after kidney transplantation. Chin J Organ Transplant 2009, 30:85-89.
41. Karimi M.H., Daneshmandi S., Pourfathollah A.A., Geramizadeh B., Malekhosseini S.A., Nikeghbalian S., et al. Association of IL-6 promoter and IFN-gamma gene polymorphisms with acute rejection of liver transplantation. Mol Biol Rep 2011, 38:4437-4443.
42. Seyhun Y., Mytilineos J., Turkmen A., Oguz F., Kekik C., Ozdilli K., et al. Influence of cytokine gene polymorphisms on graft rejection in Turkish patients with renal transplants from living related donors. Transplant Proc 2012, 44:1670-1678.
43. Karimi M.H., Daneshmandi S., Pourfathollah A.A., Geramizadeh B., Yaghobi R., Rais-Jalali G.A., et al. A study of the impact of cytokine gene polymorphism in acute rejection of renal transplant recipients. Mol Biol Rep 2012, 39:509-515.
44. Ge Y.Z., Wu R., Jia R.P., Liu H., Yu P., Zhao Y., et al. Association between interferon gamma +874T>A polymorphism and acute renal allograft rejection: evidence from published studies. Mol Biol Rep 2013, 40:6043-6051.
45. Higgins J.P., Thompson S.G., Deeks J.J., Altman D.G. Measuring inconsistency in meta-analyses. BMJ 2003, 327:557-560.
46. Mantel N., Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 1959, 22:719-748.
47. DerSimonian R., Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986, 7:177-188.
48. Thakkinstian A., McElduff P., D'Este C., Duffy D., Attia J. A method for meta-analysis of molecular association studies. Stat Med 2005, 24:1291-1306.
49. Begg C.B., Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics 1994, 50:1088-1101.
50. Egger M., Davey Smith G., Schneider M., Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997, 315:629-634.
51. Opelz G., Dohler B. Influence of time of rejection on long-term graft survival in renal transplantation. Transplantation 2008, 85:661-666.
52. Halloran P.F. Immunosuppressive drugs for kidney transplantation. N Engl J Med 2004, 351:2715-2729.
53. Xie H.G. Personalized immunosuppressive therapy in pediatric heart transplantation: progress, pitfalls and promises. Pharmacol Ther 2010, 126:146-158.
54. Dai J., Michineau S., Franck G., Desgranges P., Becquemin J.P., Gervais M., et al. Long term stabilization of expanding aortic aneurysms by a short course of cyclosporine A through transforming growth factor-beta induction. PLoS One 2011, 6:e28903.
55. Pakosz K., Zakliczynski M., Krol W., Pyka L., Zakliczynska H., Trybunia D., et al. Association of transforming growth factor beta1 (TGF-beta1) with gingival hyperplasia in heart transplant patients undergoing cyclosporine-A treatment. Ann Transplant 2012, 17:45-52.
56. Lv R., Hu X., Bai Y., Long H., Xu L., Liu Z., et al. Association between IL-6-174G/C polymorphism and acute rejection of renal allograft: evidence from a meta-analysis. Transpl Immunol 2012, 26:11-18.
57. Perrey C., Pravica V., Sinnott P.J., Hutchinson I.V. Genotyping for polymorphisms in interferon-gamma, interleukin-10, transforming growth factor-beta 1 and tumour necrosis factor-alpha genes: a technical report. Transpl Immunol 1998, 6:193-197.
58. Yamada Y., Miyauchi A., Goto J., Takagi Y., Okuizumi H., Kanematsu M., et al. Association of a polymorphism of the transforming growth factor-beta1 gene with genetic susceptibility to osteoporosis in postmenopausal Japanese women. J Bone Miner Res 1998, 13:1569-1576.
59. Dunning A.M., Ellis P.D., McBride S., Kirschenlohr H.L., Healey C.S., Kemp P.R., et al. A transforming growth factorbeta1 signal peptide variant increases secretion in vitro and is associated with increased incidence of invasive breast cancer. Cancer Res 2003, 63:2610-2615.