Association between IL-6 -174G/C polymorphism and acute rejection of renal allograft: Evidence from a meta-analysis

Transplant Immunology

Volumn 26, Issue 1, 2012, Pages 11-18

  Lv, Ruixue ^a   Hu, Xin ^a   Bai, Yi ^a   Long, Hongyu ^a   Xu, Luhang ^a   Liu, Zhenhua ^a   Li, Xiao ^a   Huang, Hengjian ^a   Wang, Lanlan ^a   Ying, Binwu ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

Acute rejection; IL 6; Meta analysis; Polymorphism; Renal transplantation

Indexed keywords

AZATHIOPRINE; CYCLOSPORIN A; CYTOSINE; GUANINE; INTERLEUKIN 6; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; TACROLIMUS;

ACUTE GRAFT REJECTION; AMINO ACID SUBSTITUTION; ASIAN; CAUCASIAN; EMBASE; ETHNICITY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; KIDNEY ALLOGRAFT REJECTION; MEDLINE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; REVIEW; RISK ASSESSMENT; SINGLE STRAND CONFORMATION POLYMORPHISM; SYSTEMATIC REVIEW;

ACUTE DISEASE; ADULT; FEMALE; GRAFT REJECTION; HUMANS; INTERLEUKIN-6; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; TRANSPLANTATION, HOMOLOGOUS;

EID: 82955242536     PISSN: 09663274     EISSN: 18785492     Source Type: Journal    
DOI: 10.1016/j.trim.2011.10.003     Document Type: Review

References (55)

1. Hariharan S., Alexander J.W., Schroeder T.J., First M.R. Impact of first acute rejection episode and severity of rejection on cadaveric renal allograft survival. Clin Transplant 1996, 10:538-541.
2. Matas A.J., Gillingham K.J., Payne W.D., Najarian J.S. The impact of an acute rejection episode on long-term renal allograft survival (t1/2). Transplantation 1994, 57:857-859.
3. Vanrenterghem Y.F. Acute rejection and renal allograft outcome. Nephrol Dial Transplant 1995, 10(Suppl. 1):29-31.
4. Kutukculer N., Clark K., Rigg K.M., Forsythe J.L., Proud G., Taylor R.M., et al. The value of posttransplant monitoring of interleukin (IL)-2, IL-3, IL-4, IL-6, IL-8, and soluble CD23 in the plasma of renal allograft recipients. Transplantation 1995, 59:333-340.
5. Blancho G., Moreau J.F., Chabannes D., Chatenoud L., Soulillou J.P. HILDA/LIF, G.CSF, IL-1 beta, IL-6, and TNF alpha production during acute rejection of human kidney allografts. Transplantation 1993, 56:597-602.
6. Dorge S.E., Roux-Lombard P., Dayer J.M., Koch K.M., Frei U., Lonnemann G. Plasma levels of tumor necrosis factor (TNF) and soluble TNF receptors in kidney transplant recipients. Transplantation 1994, 58:1000-1008.
7. Minguela A., Torio A., Marin L., Sanchez-Bueno F., Garcia-Alonso A.M., Ontanon J., et al. Implication of Th1, Th2, and Th3 cytokines in liver graft acceptance. Transplant Proc 1999, 31:519-520.
8. Karczewski J., Karczewski M., Glyda M., Wiktorowicz K. Role of TH1/TH2 cytokines in kidney allograft rejection. Transplant Proc 2008, 40:3390-3392.
9. Dallman M.J., Wood K.J., Hamano K., Bushell A.R., Morris P.J., Wood M.J., et al. Cytokines and peripheral tolerance to alloantigen. Immunol Rev 1993, 133:5-18.
10. Kishimoto T., Akira S., Taga T. Interleukin-6 and its receptor: a paradigm for cytokines. Science 1992, 258:593-597.
11. Kopf M., Baumann H., Freer G., Freudenberg M., Lamers M., Kishimoto T., et al. Impaired immune and acute-phase responses in interleukin-6-deficient mice. Nature 1994, 368:339-342.
12. Gauldie J., Richards C., Harnish D., Lansdorp P., Baumann H. Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells. Proc Natl Acad Sci U S A 1987, 84:7251-7255.
13. Vandenbroecke C., Caillat-Zucman S., Legendre C., Noel L.H., Kreis H., Woodrow D., et al. Differential in situ expression of cytokines in renal allograft rejection. Transplantation 1991, 51:602-609.
14. Bidwell J., Keen L., Gallagher G., Kimberly R., Huizinga T., McDermott M.F., et al. Cytokine gene polymorphism in human disease: on-line databases. Genes Immun 1999, 1:3-19.
15. Fishman D., Faulds G., Jeffery R., Mohamed-Ali V., Yudkin J.S., Humphries S., et al. The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. J Clin Invest 1998, 102:1369-1376.
16. Tajik N., Kazemi T., Delbandi A., Ghods A., Salek Moghaddam A. The predictive value of HLA-DR matching and cytokine gene polymorphisms in renal allograft acute rejection: a Living-unrelated Donor (LURD) study. Iran J Immunol 2006, 3:150-156.
17. Kocierz M., Siekiera U., Kolonko A., Karkoszka H., Chudek J., Cierpka L., et al. 174G/C interleukin-6 gene polymorphism and the risk of transplanted kidney failure or graft loss during a 5-year follow-up period. Tissue Antigens 2011, 77:283-290.
18. Canossi A., Piazza A., Poggi E., Ozzella G., Di Rocco M., Papola F., et al. Renal allograft immune response is influenced by patient and donor cytokine genotypes. Transplant Proc 2007, 39:1805-1812.
19. Cartwright N.H., Keen L.J., Demaine A.G., Hurlock N.J., McGonigle R.J., Rowe P.A., et al. A study of cytokine gene polymorphisms and protein secretion in renal transplantation. Transpl Immunol 2001, 8:237-244.
20. Karimi M.H., Daneshmandi S., Pourfathollah A.A., Geramizadeh B., Yaghobi R., Rais-Jalali G.A., et al. A study of the impact of cytokine gene polymorphism in acute rejection of renal transplant recipients. Mol Biol Rep 2011, [Electronic publication ahead of print 2011 May 12].
21. Marshall S.E., McLaren A.J., McKinney E.F., Bird T.G., Haldar N.A., Bunce M., et al. Donor cytokine genotype influences the development of acute rejection after renal transplantation. Transplantation 2001, 71:469-476.
22. Moher D., Liberati A., Tetzlaff J., Altman D.G. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med 2009, 6:e1000097.
23. Pourfathollah A.A., Daneshmandi S., Karimi M.H., Geramizadeh B. Cytokine gene polymorphisms as risk factors in acute rejection in renal transplantation. Cytokine 2009, 48:97.
24. Ebadi P., Karimi M.H., Pourfathollah A.A., Daneshmandi S., Germizadeh B. IL-6 and IFN-Y polymorphism, a risk factor for acute rejection of kidney transplantation. Vox Sang 2010, 99:499.
25. Masri M.A., Barbari A., Stephan A., Rizk S., Kamel G. Cytokine gene polymorphism in a Lebanese transplant population and its impact on graft acceptance: a single-center pilot study. Transplant Proc 2003, 35:251-252.
26. Lacha J., Hribova P., Kotsch K., Brabcova I., Bartosova K., Volk H.D., et al. Effect of cytokines and chemokines (TGF-beta, TNF-alpha, IL-6, IL-10, MCP-1, RANTES) gene polymorphisms in kidney recipients on posttransplantation outcome: influence of donor-recipient match. Transplant Proc 2005, 37:764-766.
27. Loucaidou M., Stitchbury J., Lee J., Borrows R., Marshall S.E., McLean A.G., et al. Cytokine polymorphisms do not influence acute rejection in renal transplantation under tacrolimus-based immunosuppression. Transplant Proc 2005, 37:1760-1761.
28. Kruger B., Walberer A., Farkas S., Tokmak F., Obed A., Schenker P., et al. The impact of "high-producer" interleukin-6 haplotypes on cardiovascular morbidity and mortality in a kidney transplant population. Transplant Proc 2009, 41:2539-2543.
29. Breulmann B., Bantis C., Siekierka M., Blume C., Aker S., Kuhr N., et al. Influence of cytokine genes polymorphisms on long-term outcome in renal transplantation. Clin Transplant 2007, 21:615-621.
30. Gu X.W., Zhao M., Li L.Y., Li M., Qian J. Cytokine gene polymorphism in sensitized kidney transplant recipients and its association with acute rejection episodes. Di Yi Jun Yi Da Xue Xue Bao 2003, 23:1211-1213.
31. Huang X.E., Fan L.P., Li L.Y., Zhao M., Xia S.S. Risk factors of acute rejection in sensitized kidney transplant recipients. Di Yi Jun Yi Da Xue Xue Bao 2004, 24:1188-1191.
32. Cho W.H., Kim H.T., Sohn C.Y., Park C.H., Park S.B., Kim H.C. Significance of IL-2, IL-2R, IL-6, and TNF-alpha as a diagnostic test of acute rejection after renal transplantation. Transplant Proc 1998, 30:2967-2969.
33. Daniel V., Arzberger J., Melk A., Weimer R., Ruhenstroth A., Carl S., et al. Predictive indicators of rejection or infection in renal transplant patients. Transplant Proc 1999, 31:1364-1365.
34. Boratynska M. Interleukin-6 in chronic renal allograft rejection: influence of nonimmunologic risk factors. Transplant Proc 2001, 33:1215-1217.
35. Diller R., Palmes D., Dietl K.H., Senninger N., Winde G., Spiegel H.U. Interleukin-6, interleukin-8, and interleukin-10 in kidney transplantation: improved risk strategy?. Transplant Proc 2003, 35:1333-1337.
36. Neumann J., Fernandes S., Keitel E., Santos A., Santos P., Michelon T., et al. Cytokine polymorphism and kidney graft survival at a single center. Transplant Proc 2001, 33:501.
37. Poli F., Boschiero L., Giannoni F., Tonini M., Ancona G., Scalamogna M., et al. TNF-(alpha) IFN-(gamma) IL-6, IL-10, and TGF-(beta)1 gene polymorphisms in renal allografts. Transplant Proc 2001, 33:348-349.
38. Kocierz M., Kujawa-Szewieczek A., Kolonko A., Chudek J., Wiecek A. The influence of selected cytokine gene polymorphisms on the occurrence of acute and chronic rejection and on kidney graft survival. Postepy Hig Med Dosw (Online) 2009, 63:613-626.
39. McDaniel D.O., Barber W.H., Nguyan C., Rhodes S.W., May W.L., McDaniel L.S., et al. Combined analysis of cytokine genotype polymorphism and the level of expression with allograft function in African-American renal transplant patients. Transpl Immunol 2003, 11:107-119.
40. Tian Y., Ma W., Zhang Y. Influence of cytokine gene polymorphism on renal transplantation. Zhonghua Yi Xue Za Zhi 2001, 81:719-721.
41. Tian Y., Ma W., Zhang Y. Influence of cytokine gene polymorphism on renal transplantation. Zhonghua Wai Ke Za Zhi 2002, 40:256-258.
42. Alakulppi N.S., Kyllonen L.E., Jantti V.T., Matinlauri I.H., Partanen J., Salmela K.T., et al. Cytokine gene polymorphisms and risks of acute rejection and delayed graft function after kidney transplantation. Transplantation 2004, 78:1422-1428.
43. Hoffmann S., Park J., Jacobson L.M., Muehrer R.J., Lorentzen D., Kleiner D., et al. Donor genomics influence graft events: the effect of donor polymorphisms on acute rejection and chronic allograft nephropathy. Kidney Int 2004, 66:1686-1693.
44. Guo Y.F., Tan J.M., Li R.Y., Liu S.Z., Li Y., Ying K., et al. Impacts of donor and recipient's SNP of cytokine and cytokine receptor on early acute renal allograft rejection. Natl Med J China 2005, 85:3126-3133.
45. Ligeiro D., Sancho M.R., Papoila A., Barradinhas A.M., Almeida A., Calao S., et al. Impact of donor and recipient cytokine genotypes on renal allograft outcome. Transplant Proc 2004, 36:827-829.
46. Manchanda P.K., Mittal R.D. Analysis of cytokine gene polymorphisms in recipient's matched with living donors on acute rejection after renal transplantation. Mol Cell Biochem 2008, 311:57-65.
47. Gendzekhadze K., Rivas-Vetencourt P., Montano R.F. Risk of adverse post-transplant events after kidney allograft transplantation as predicted by CTLA-4 +49 and TNF-alpha -308 single nucleotide polymorphisms: a preliminary study. Transpl Immunol 2006, 16:194-199.
48. Hahn A.B., Kasten-Jolly J.C., Constantino D.M., Graffunder E., Singh T.P., Shen G.K., et al. TNF-alpha, IL-6, IFN-gamma, and IL-10 gene expression polymorphisms and the IL-4 receptor alpha-chain variant Q576R: effects on renal allograft outcome. Transplantation 2001, 72:660-665.
49. Marshall S.E., McLaren A.J., Haldar N.A., Bunce M., Morris P.J., Welsh K.I. The impact of recipient cytokine genotype on acute rejection after renal transplantation. Transplantation 2000, 70:1485-1491.
50. Reviron D., Dussol B., Andre M., Brunet P., Mercier P., Berland Y. TNF-alpha and IL-6 gene polymorphism and rejection in kidney transplantation recipients. Transplant Proc 2001, 33:350-351.
51. Karimi M.H., Daneshmandi S., Pourfathollah A.A., Geramizadeh B., Yaghobi R., Rais-Jalali G.A., et al. A study of the impact of cytokine gene polymorphism in acute rejection of renal transplant recipients. Mol Biol Rep 2011, 1-7.
52. Knight R.J., Burrows L., Bodian C. The influence of acute rejection on long-term renal allograft survival: a comparison of living and cadaveric donor transplantation. Transplantation 2001, 72:69-76.
53. Ferguson R. Acute rejection episodes-best predictor of long-term primary cadaveric renal transplant survival. Clin Transplant 1994, 8:328-331.
54. Wilson A.G., Symons J.A., McDowell T.L., McDevitt H.O., Duff G.W. Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. Proc Natl Acad Sci U S A 1997, 94:3195-3199.
55. Turner D.M., Williams D.M., Sankaran D., Lazarus M., Sinnott P.J., Hutchinson I.V. An investigation of polymorphism in the interleukin-10 gene promoter. Eur J Immunogenet 1997, 24:1-8.