Naloxone postconditioning alleviates rat myocardial ischemia reperfusion injury by inhibiting JNK activity

Korean Journal of Physiology and Pharmacology

Volumn 18, Issue 1, 2014, Pages 67-72

  Xia, Anzhou ^a   Xue, Zhi ^a   Wang, Wei ^a   Zhang, Tan ^a   Wei, Tiantian ^a   Sha, Xingzhi ^b   Ding, Yixun ^b   Zhou, Weidong ^b  

^a XUZHOU MEDICAL UNIVERSITY   (China)

^b Suining County Hospital   (China)

Author keywords

C Jun N terminal kinases (JNK); Cell apoptosis; Ischemia reperfusion; Naloxone

Indexed keywords

EOSIN; HEMATOXYLIN; NALOXONE; STRESS ACTIVATED PROTEIN KINASE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEGENERATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MEGADOSE; ENZYME ACTIVITY; ENZYME INHIBITION; HEART; HEART MUSCLE CELL; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; INFLAMMATORY CELL; INFLAMMATORY INFILTRATE; ISCHEMIC POSTCONDITIONING; LOW DRUG DOSE; MALE; MYOCARDIAL ISCHEMIA REPERFUSION INJURY; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; RAT; REPERFUSION INJURY; STAINING; WESTERN BLOTTING;

EID: 84896516242     PISSN: 12264512     EISSN: 20933827     Source Type: Journal    
DOI: 10.4196/kjpp.2014.18.1.67     Document Type: Article

References (22)

1. Sekikawa A, Horiuchi BY, Edmundowicz D, Ueshima H, Curb JD, Sutton-Tyrrell K, Okamura T, Kadowaki T, Kashiwagi A, Mitsunami K, Murata K, Nakamura Y, Rodriguez BL, Kuller LH. A "natural experiment" in cardiovascular epidemiology in the early 21st century. Heart. 2003;89:255-257. (Pubitemid 36241529)
2. Zhao ZQ, Corvera JS, Halkos ME, Kerendi F, Wang NP, Guyton RA, Vinten-Johansen J. Inhibition of myocardial injury by ischemic postconditioning during reperfusion: comparison with ischemic preconditioning. Am J Physiol Heart Circ Physiol. 2003;285:H579-588. (Pubitemid 36885888)
3. Zhu M, Feng J, Lucchinetti E, Fischer G, Xu L, Pedrazzini T, Schaub MC, Zaugg M. Ischemic postconditioning protects remodeled myocardium via the PI3K-PKB/Akt reperfusion injury salvage kinase pathway. Cardiovasc Res. 2006;72:152-162. (Pubitemid 44310638)
4. Zhang W, Miao Y, Zhou S, Jiang J, Luo Q, Qiu Y. Neuroprotective effects of ischemic postconditioning on global brain ischemia in rats through upregulation of hippocampal glutamine synthetase. J Clin Neurosci. 2011;18:685-689.
5. Penna C, Pasqua T, Perrelli MG, Pagliaro P, Cerra MC, Angelone T. Postconditioning with glucagon like peptide-2 reduces ischemia/reperfusion injury in isolated rat hearts: role of survival kinases and mitochondrial KATP channels. Basic Res Cardiol. 2012;107:272.
6. Glembotski CC, Thuerauf DJ, Huang C, Vekich JA, Gottlieb RA, Doroudgar S. Mesencephalic astrocyte-derived neurotrophic factor protects the heart from ischemic damage and is selectively secreted upon sarco/endoplasmic reticulum calcium depletion. J Biol Chem. 2012;287:25893-25904.
7. Chen S, Liu J, Liu X, Fu Y, Zhang M, Lin Q, Zhu J, Mai L, Shan Z, Yu X, Yang M, Lin S. Panax notoginseng saponins inhibit ischemia-induced apoptosis by activating PI3K/Akt pathway in cardiomyocytes. J Ethnopharmacol. 2011;137:263-270.
8. Liu Y, Liao X, Xue FS, Xu YC, Xiong J, Yuan YJ, Wang Q, Liu JH, Zhao JX. Effects of combined ischemic postconditioning, remote ischemic postconditioning and naloxone postconditioning on focal cerebral ischemia-reperfusion injury in rats. Zhonghua Yi Xue Za Zhi. 2011;91:1493-1497.
9. Mutoh J, Ohsawa M, Hisa H. Effect of naloxone on ischemic acute kidney injury in the mouse. Neuropharmacology. 2013;71:10-18.
10. Zhang T, Zhou WD, Xia AZ, Gu SL. Effect of p38 MAPK on naloxone alleviating myocardial ischemia reperfusion injury in rats. West China Journal of Pharmaceutical Sciences. 2011;26:460-462.
11. Gottlieb RA, Burleson KO, Kloner RA, Babior BM, Engler RL. Reperfusion injury induces apoptosis in rabbit cardiomyocytes. J Clin Invest. 1994;94:1621-1628. (Pubitemid 24309885)
12. Ferrandi C, Ballerio R, Gaillard P, Giachetti C, Carboni S, Vitte PA, Gotteland JP, Cirillo R. Inhibition of c-Jun. N-terminal kinase decreases cardiomyocyte apoptosis and infarct size after myocardial ischemia and reperfusion in anaesthetized rats. Br J Pharmacol. 2004;142:953-960. (Pubitemid 39037045)
13. Hori M, Nishida K. Oxidative stress and left ventricular remodelling after myocardial infarction. Cardiovasc Res. 2009;81:457-464.
14. Jiang CM, Xu CQ, Mi Y, Li HZ, Wang R, Li WM. Calciumsensing receptor induced myocardial ischemia/reperfusion injury via the c-Jun. NH2-terminal protein kinase pathway. Acta Cardiol Sin. 2010;26:102-110.
15. Matsumoto N, Imamura R, Suda T. Caspase-8- and JNK-dependent AP-1 activation is required for Fas ligand-induced IL-8 production. FEBS J. 2007;274:2376-2384. (Pubitemid 46633464)
16. Lee SE, Lim JW, Kim H. Activator protein-1 mediates docosahexaenoic acid-induced apoptosis of human gastric cancer cells. Ann N Y Acad Sci. 2009;1171:163-169.
17. Setoguchi D, Kakihana Y. Naloxone. Masui. 2013;62:5-9.
18. Zhou P, Dong CL, Niu RX, Wu JX, Li YH. The effects of naloxone in free oxygen radical during myocardial ischemiareperfusion period. Journal of Medical Research. 2008;37:56-57.
19. Qin YH, Shen H, Yang YS, Wen TB, Li TD. Naloxone inhibits generation of IL-8 and TXA2 from Ischemic and reperfused myocardium. Pharmaceutical J Chin People's Liberation Army. 2008;24:23-25.
20. Wong GT, Li R, Jiang LL, Irwin MG. Remifentanil postconditioning attenuates cardiac ischemia-reperfusion injury via kappa or delta opioid receptor activation. Acta Anaesthesiol Scand. 2010;54:510-518.
21. Zhang Y, Irwin MG, Wong TM. Remifentanil preconditioning protects against ischemic injury in the intact rat heart. Anesthesiology. 2004;101:918-923. (Pubitemid 39288042)
22. Weber TP, Raufbake C, Grosse Hartlage MA, Rolf N, Stypmann J, Van Aken H, Berendes E, Meissner A. Naloxone prevents increased atrial natriuretic peptide release during regional myocardial ischaemia and stunning in awake dogs. Br J Anaesth. 2002;88:87-93. (Pubitemid 34048567)