Ginsenoside Rb1 protects hippocampal neurons from high glucose-induced neurotoxicity by inhibiting GSK3β-mediated CHOP induction

Molecular Medicine Reports

Volumn 9, Issue 4, 2014, Pages 1434-1438

  Liu, Di ^a   Zhang, Hong ^b   Gu, Wenjuan ^a   Liu, Yuqin ^b   Zhang, Mengren ^a  

^a PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^b PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

Endoplasmic reticulum stress; Ginsenoside Rb1; GSK3 ; High glucose; Hippocampal neurons

Indexed keywords

GINSENOSIDE RB 1; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3BETA; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; MESSENGER RNA; PROTEIN KINASE; PROTEIN KINASE RNA LIKE ER KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL LOSS; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENDOPLASMIC RETICULUM STRESS; ENZYME INHIBITION; GENE EXPRESSION; HIPPOCAMPAL NEURONAL CULTURE; MTT ASSAY; NERVE CELL LESION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; CELL DEATH; CELL SHAPE; CELL SURVIVAL; ENDOPLASMIC RETICULUM STRESS; GINSENOSIDES; GLUCOSE; GLYCOGEN SYNTHASE KINASE 3; HIPPOCAMPUS; NEURONS; NEUROPROTECTIVE AGENTS; NEUROTOXINS; RATS; RATS, SPRAGUE-DAWLEY; TRANSCRIPTION FACTOR CHOP;

EID: 84896509227     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.1958     Document Type: Article

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