Targeting histidine side chains in molecular design through nitrogen-halogen bonds

Journal of Chemical Information and Modeling

Volumn 53, Issue 12, 2013, Pages 3178-3189

  Lange, Andreas ^a   Zimmermann, Markus O ^a   Wilcken, Rainer ^a   Zahn, Stefan ^b   Boeckler, Frank M ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BINDING SITES; IONS; NITROGEN; QUANTUM CHEMISTRY;

BINDING AFFINITIES; CANDIDATE SELECTION; MOLECULAR DESIGN; NON-COVALENT INTERACTION; PATENT APPLICATIONS; PROTEIN-BINDING SITES; QUANTUM CHEMICAL CALCULATIONS; TARGET ELECTRONS;

BINDING ENERGY;

BROMOBENZENE; CHLOROBENZENE; ENZYME INHIBITOR; FARNESYL TRANS TRANSFERASE; HISTIDINE; IMIDAZOLE; IMIDAZOLE DERIVATIVE; IODOBENZENE; LIGAND;

ARTICLE; CHEMICAL MODEL; CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; HUMAN; QUANTUM THEORY; STATIC ELECTRICITY; THERMODYNAMICS;

BROMOBENZENES; CHLOROBENZENES; DRUG DESIGN; ENZYME INHIBITORS; FARNESYLTRANSTRANSFERASE; HISTIDINE; HUMANS; IMIDAZOLES; IODOBENZENES; LIGANDS; MODELS, CHEMICAL; QUANTUM THEORY; STATIC ELECTRICITY; THERMODYNAMICS;

EID: 84896508445     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci4004305     Document Type: Article

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