Ispaghula mucilage-gellan mucoadhesive beads of metformin HCl: Development by response surface methodology

Carbohydrate Polymers

Volumn 107, Issue 1, 2014, Pages 41-50

  Nayak, Amit Kumar ^a   Pal, Dilipkumar ^b   Santra, Kousik ^a  

^a SEEMANTA INSTITUTE OF PHARMACEUTICAL SCIENCES   (India)

^b GURU GHASIDAS UNIVERSITY   (India)

Author keywords

Controlled drug release; Gellan gum; Ispaghula husk; Mucilage; Mucoadhesion; Response surface methodology

Indexed keywords

ADHESIVES; DRUG DELIVERY; IONOTROPIC GELATION; OPTIMIZATION; SURFACE PROPERTIES;

CONTROLLED DRUG RELEASE; GELLAN GUM; ISPAGHULA HUSK; MUCILAGE; MUCOADHESION; RESPONSE SURFACE METHODOLOGY;

DRUG PRODUCTS;

BACTERIAL POLYSACCHARIDE; DRUG CARRIER; GELLAN; METFORMIN; MICROSPHERE; MUCILAGE;

ADHESION; ANIMAL; CHEMISTRY; COMPUTER AIDED DESIGN; DIABETES MELLITUS, EXPERIMENTAL; FEMALE; MALE; MUCILAGE; MUCOSA; PH; PLANTAGO; RAT;

ADHESIVENESS; ANIMALS; COMPUTER-AIDED DESIGN; DIABETES MELLITUS, EXPERIMENTAL; DRUG CARRIERS; FEMALE; HYDROGEN-ION CONCENTRATION; MALE; METFORMIN; MICROSPHERES; MUCOUS MEMBRANE; PLANT MUCILAGE; PLANTAGO; POLYSACCHARIDES, BACTERIAL; RATS;

EID: 84896507372     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2014.02.022     Document Type: Article

References (31)

1. M. Ahuja, M. Yadav, and S. Kumar Application of response surface methodology to formulation of ionotropically gelled gum cordial/gellan beads Carbohydrate Polymers 80 2010 161 167
2. R.J. Babu, S. Sathigrahi, M.T. Kumar, and J.K. Pandit Formulation of controlled release gellan gum macro beads of amoxicillin Current Drug Delivery 7 2010 36 43
3. S.C. Basak, K.S. Kumar, and M. Ramalingam Design and release characteristics of sustained release tablet containing metformin HCl Brazilian Journal of Pharmaceutical Sciences 44 2008 477 483
4. 2 full factorial design Current Drug Delivery 7 2009 36 43
5. R.S. Deveswaran, S. Furtado, S. Bharath, S. Abraham, B.V. Basavaraj, and V. Madhavan Evaluation of disintegrants properties of Plantago ovata mucilage in comparison with other super disintegrants Archives of Pharmaceutical Sciences and Research 2 2010 230 235
6. M.O. Emeje, P.I.F. Franklin-Ude, and S.I. Odoefule Evaluation of fluid uptake kinetics and drug release from gellan gum tablets containing metronidazole International Journal of Biological Macromolecules 47 2010 158 163
7. P.R. Guru, A.K. Nayak, and R.K. Sahu Oil-entrapped sterculia gum-alginate buoyant systems of aceclofenac: development and in vitro evaluation Colliods Surfaces B: Biointerfaces 104 2013 268 275
8. M. Hamcerencu, J. Desbrieres, A. Khoukh, M. Popa, and G. Riess Synthesis and characterization of new unsaturated esters of gellan gum Carbohydrate Polymers 71 2008 92 100 (Pubitemid 350017842)
9. S. Jana, A. Das, A.K. Nayak, K.K. Sen, and S.K. Basu Aceclofenac-loaded unsaturated esterified alginate-gellan gum microspheres: in vitro and in vivo assessment International Journal of Biological Macromolecules 57 2013 129 137
10. R.V. Kulkarni, B.S. Mangod, S. Mutalik, and B. Sa Interpenetrating polymer network microcapsules of gellan gum and egg albumin entrapped with diltiazem-resin complex for controlled release application Carbohydrate Polymers 83 2011 1001 1007
11. R.V. Kulkarni, V.V. Nagathan, P.R. Biradar, and A.A. Naikawadi Simvastatin loaded composite polyspheres of gellan gum and carrageenan: in vitro and in vivo evaluation International Journal of Biological Macromolecules 57 2013 238 244
12. A. Kumar, and M. Ahuja Carboxymethyl gum kondagogu: synthesis, characterization and evaluation as mucoadhesive polymer Carbohydrate Polymers 90 2012 637 643
13. 3+ ion cross-linked and acetalated gellan hydrogel network beads for prolonged release of glipizide Carbohydrate Polymers 85 2011 164 172
14. 3-factorial design Chemical Engineering Research and Design 9 2012 1834 1846
15. J. Malakar, A.K. Nayak, and D. Pal Development of cloxacillin loaded multiple-unit alginate-based floating system by emulsion-gelation method International Journal of Biological Macromolecules 50 2012 138 147
16. M. Narker, P. Sher, and A. Pawar Stomach-specific controlled release gellan beads of acid-soluble drug prepared by ionotropic gelation method AAPS PharmSciTech 11 2010 267 277
17. A.K. Nayak, and D. Pal Development of pH-sensitive tamarind seed polysaccharide-alginate composite beads for controlled diclofenac sodium delivery using response surface methodology International Journal of Biological Macromolecules 49 2011 784 793
18. A.K. Nayak, and D. Pal Ionotropically-gelled mucoadhesive beads for oral metformin HCl delivery: Formulation, optimization and antidiabetic evaluation Journal of Scientific and Industrial Research 72 2013 15 22
19. A.K. Nayak, D. Pal, and S. Das Calcium pectinate-fenugreek seed mucilage mucoadhesive beads for controlled delivery of metformin HCl Carbohydrate Polymers 96 2013 349 357
20. A.K. Nayak, D. Pal, J. Pradhan, and M.S. Hasnain Fenugreek seed mucilage-alginate mucoadhesive beads of metformin HCl: design, optimization and evaluation International Journal of Biological Macromolecules 54 2013 144 154
21. A.K. Nayak, D. Pal, and K. Santra Plantago ovata F. mucilage-alginate mucoadhesive beads for controlled release of glibenclamide: development, optimization and in vitro-in vivo evaluation Journal of Pharmaceutics 2013 Article ID 151035
22. A.K. Nayak, D. Pal, and K. Santra Tamarind seed polysaccharide-gellan mucoadhesive beads for controlled release of metformin HCl Carbohydrate Polymers 103 2014 154 163
23. D. Pal, and A.K. Nayak Development, optimization, and anti-diabetic activity of gliclazide-loaded alginate-methyl cellulose mucoadhesive microcapsules AAPS PharmSciTech 12 2011 1431 1441
24. S.T. Prajapati, V.D. Prajapati, and S.R. Acharya Characterization of disintegration properties of Plantago ovata mucilage in formulation of dispersible tablets Indian Journal of Pharmaceutical Education and Research 40 2006 208 211
25. V.D. Prajapati, K.H. Mashuru, H.K. Solanki, and G.K. Jani Development of modified release gliclazide biological macromolecules using natural biodegradable polymers International Journal of Biological Macromolecules 55 2013 6 14
26. 3 full-factorial design AAPS PharmSciTech 11 2010 489 496
27. V.K. Sharma, and A. Bhattyacharya Release of metformin hydrochloride from ispaghula-sodium alginate beads adhered on cock intestinal mucosa Indian Journal of Pharmaceutical Education and Research 42 2008 365 372
28. S.B. Shirsand, S. Suresh, M.S. Para, P.V. Swamy, and D.N. Kumar Plantago ovata mucilage in the design of fast disintegrating tablets International Journal of Pharmaceutical Sciences 1 2009 41 45
29. B. Singh Psyllium as therapeutic and drug delivery agent International Journal of Pharmaceutics 334 2007 1 14 (Pubitemid 46400324)
30. V. Vijan, S. Kaity, S. Biswas, J. Isaac, and A. Ghosh Microwave-assisted synthesis and characterization of acrylamide grafted gellan, application in drug delivery Carbohydrate Polymers 90 2012 496 506
31. F. Yamamoto, and R.L. Cunha Acid gelation of gellan: effect of final pH and heat treatment conditions Carbohydrate Polymers 68 2007 517 527 (Pubitemid 46365941)