Gene expression profiles of human adipose tissue-derived mesenchymal stem cells are modified by cell culture density

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Kim, Dae Seong ^a   Lee, Myoung Woo ^a   Yoo, Keon Hee ^a   Lee, Tae Hee ^b   Kim, Hye Jin ^a   Jang, In Keun ^a   Chun, Yong Hoon ^c   Kim, Hyung Joon ^c   Park, Seung Jo ^a   Lee, Soo Hyun ^a   Son, Meong Hi ^a   Jung, Hye Lim ^a   Sung, Ki Woong ^a   Koo, Hong Hoe ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Sejong University   (South Korea)

^c Topclass Plastic Surgery   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

5' NUCLEOTIDASE; ALPHA 2 MACROGLOBULIN; CD14 ANTIGEN; CD34 ANTIGEN; CD45 ANTIGEN; CXCL1 CHEMOKINE; CXCL16 CHEMOKINE; CXCL2 CHEMOKINE; ENDOGLIN; EPITHELIAL DERIVED NEUTROPHIL ACTIVATING FACTOR 78; FIBROBLAST GROWTH FACTOR 1; GRANULOCYTE CHEMOTACTIC PROTEIN 2; GROWTH DIFFERENTIATION FACTOR 15; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MIDKINE; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 2; PLATELET DERIVED GROWTH FACTOR D; THY 1 ANTIGEN; VASCULOTROPIN A; WNT1 PROTEIN;

ADIPOSE TISSUE; ADULT; ARTICLE; CELL COMMUNICATION; CELL CULTURE; CELL DENSITY; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CELLULAR IMMUNITY; CONTROLLED STUDY; DOWN REGULATION; EX VIVO STUDY; FEMALE; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOSUPPRESSIVE TREATMENT; MESENCHYMAL STEM CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TISSUE MICROARRAY; UPREGULATION;

ADIPOSE TISSUE; ADULT; CELL COUNT; CELL CULTURE TECHNIQUES; CELLS, CULTURED; CLUSTER ANALYSIS; CYTOKINES; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; MESENCHYMAL STROMAL CELLS; REPRODUCIBILITY OF RESULTS; TRANSCRIPTOME; YOUNG ADULT;

EID: 84896487062     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0083363     Document Type: Article

References (51)

1. da Silva Meirelles L, Chagastelles PC, Nardi NB (2006) Mesenchymal stem cells reside in virtually all post-natal organs and tissues. J Cell Sci 119: 2204-2213. (Pubitemid 43960310)
2. Battiwalla M, Hematti P (2009) Mesenchymal stem cells in hematopoietic stem cell transplantation. Cytotherapy 11: 503-515.
3. Tian Y, Deng YB, Huang YJ, Wang Y (2008) Bone marrow-derived mesenchymal stem cells decrease acute graft-versus-host disease after allogeneic hematopoietic stem cells transplantation. Immunol Invest 37: 29-42. (Pubitemid 351152363)
4. Barbash IM, Chouraqui P, Baron J, Feinberg MS, Etzion S, et al. (2003) Systemic delivery of bone marrow-derived mesenchymal stem cells to the infarcted myocardium: feasibility, cell migration, and body distribution. Circulation 108: 863-868. (Pubitemid 37022130)
5. Keyser KA, Beagles KE, Kiem HP (2007) Comparison of mesenchymal stem cells from different tissues to suppress T-cell activation. Cell Transplant 16: 555-562. (Pubitemid 351448291)
6. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, et al. (1999) Multilineage potential of adult human mesenchymal stem cells. Science 284: 143-147. (Pubitemid 29282067)
7. Zuk PA, Zhu M, Ashjian P, De Ugarte DA, Huang JI, et al. (2002) Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell 13: 4279-4295. (Pubitemid 35471185)
8. Jurgens WJ, Oedayrajsingh-Varma MJ, Helder MN, Zandiehdoulabi B, Schouten TE, et al. (2008) Effect of tissue-harvesting site on yield of stem cells derived from adipose tissue: implications for cell-based therapies. Cell Tissue Res 332: 415-426. (Pubitemid 351677811)
9. Lee RH, Hsu SC, Munoz J, Jung JS, Lee NR, et al. (2006) A subset of human rapidly self-renewing marrow stromal cells preferentially engraft in mice. Blood 107: 2153-2161. (Pubitemid 43289401)
10. Kern S, Eichler H, Stoeve J, Kluter H, Bieback K (2006) Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue. Stem Cells 24: 1294-1301. (Pubitemid 44464698)
11. Hwang JH, Shim SS, Seok OS, Lee HY, Woo SK, et al. (2009) Comparison of cytokine expression in mesenchymal stem cells from human placenta, cord blood, and bone marrow. J Korean Med Sci 24: 547-554.
12. Lee RH, Seo MJ, Pulin AA, Gregory CA, Ylostalo J, et al. (2009) The CD34-like protein PODXL and alpha6-integrin (CD49f) identify early progenitor MSCs with increased clonogenicity and migration to infarcted heart in mice. Blood 113: 816-826.
13. Colter DC, Sekiya I, Prockop DJ (2001) Identification of a subpopulation of rapidly self-renewing and multipotential adult stem cells in colonies of human marrow stromal cells. Proc Natl Acad Sci U S A 98: 7841-7845. (Pubitemid 32642648)
14. English K, French A, Wood KJ (2010) Mesenchymal stromal cells: facilitators of successful transplantation?. Cell Stem Cell 7: 431-442.
15. Robinson SN, Simmons PJ, Yang H, Alousi AM, Marcos de Lima J, et al. (2011) Mesenchymal stem cells in ex vivo cord blood expansion. Best Pract Res Clin Haematol 24: 83-92.
16. Webb TL, Quimby JM, Dow SW (2012) In vitro comparison of feline bone marrow-derived and adipose tissue-derived mesenchymal stem cells. J Feline Med Surg 14: 165-168.
17. da Silva Meirelles L, Caplan AI, Nardi NB (2008) In search of the in vivo identity of mesenchymal stem cells. Stem Cells 26: 2287-2299.
18. Meirelles Lda S, Fontes AM, Covas DT, Caplan AI (2009) Mechanisms involved in the therapeutic properties of mesenchymal stem cells. Cytokine Growth Factor Rev 20: 419-427.
19. Ho AD, Wagner W, Franke W (2008) Heterogeneity of mesenchymal stromal cell preparations. Cytotherapy 10: 320-330. (Pubitemid 351983156)
20. Reyes M, Lund T, Lenvik T, Aguiar D, Koodie L, et al. (2001) Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells. Blood 98: 2615-2625.
21. Sotiropoulou PA, Perez SA, Salagianni M, Baxevanis CN, Papamichail M (2006) Characterization of the optimal culture conditions for clinical scale production of human mesenchymal stem cells. Stem Cells 24: 462-471. (Pubitemid 44464816)
22. Strieter RM, Polverini PJ, Kunkel SL, Arenberg DA, Burdick MD, et al. (1995) The functional role of the ELR motif in CXC chemokine-mediated angiogenesis. J Biol Chem 270: 27348-27357.
23. Matloubian M, David A, Engel S, Ryan JE, Cyster JG (2000) A transmembrane CXC chemokine is a ligand for HIV-coreceptor Bonzo. Nat Immunol 1: 298-304.
24. Melief SM, Zwaginga JJ, Fibbe WE, Roelofs H (2013) Adipose tissue-derived multipotent stromal cells have a higher immunomodulatory capacity than their bone marrow-derived counterparts. Stem Cells Transl Med 2: 455-463.
25. De Ugarte DA, Alfonso Z, Zuk PA, Elbarbary A, Zhu M, et al. (2003) Differential expression of stem cell mobilization-associated molecules on multi-lineage cells from adipose tissue and bone marrow. Immunol Lett 89: 267-270. (Pubitemid 37222456)
26. Schäffler A, Büchler C (2007) Concise review: adipose tissue-derived stromal cells-basic and clinical implications for novel cell-based therapies. Stem Cells 25: 818-827.
27. Zuk PA, Zhu M, Ashjian P, De Ugarte DA, Huang JI, et al. (2002) Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell 13: 4279-4295. (Pubitemid 35471185)
28. Braun J, Kurtz A, Barutcu N, Bodo J, Thiel A, et al. (2013) Concerted regulation of CD34 and CD105 accompanies mesenchymal stromal cell derivation from human adventitial stromal cell. Stem Cells Dev 22: 815-827.
29. Lee MW, Kim DS, Ryu S, Jang IK, Kim HJ, et al. (2013) Effect of ex vivo culture conditions on immunosuppression by human mesenchymal stem cells. Biomed Res Int 2013:154919.
30. Miyasaka M, Tanaka T (2004) Lymphocyte trafficking across high endothelial venules: dogmas and enigmas. Nat Rev Immunol 4: 360-370. (Pubitemid 38649278)
31. Strieter RM, Belperio JA, Burdick MD, Keane MP (2005) CXC chemokines in angiogenesis relevant to chronic fibroproliferation. Curr Drug Targets Infl amm Allergy 4: 23-26. (Pubitemid 40590030)
32. Bièche I, Chavey C, Andrieu C, Busson M, Vacher S, et al. (2007) CXC chemokines located in the 4q21 region are up-regulated in breast cancer. Endocr Relat Cancer 14: 1039-1052. (Pubitemid 351252435)
33. Wilbanks A, Zondlo SC, Murphy K, Mak S, Soler D, et al. (2001) Expression cloning of the STRL33/BONZO/TYMSTR ligand reveals elements of CC, CXC, and CX3C chemokines. J Immunol 166: 5145-5154. (Pubitemid 32280729)
34. Li JT, Hou FF, Guo ZJ, Shan YX, Zhang X, et al. (2007) Advanced glycation end products upregulate C-reactive protein synthesis by human hepatocytes through stimulation of monocyte IL-6 and IL-1 beta production. Scand J Immunol 66: 555-562. (Pubitemid 47609694)
35. Carrero R, Cerrada I, Lledó E, Dopazo J, García- García F, et al. (2012) IL1β induces mesenchymal stem cells migration and leucocyte chemotaxis through NF-κB. Stem Cell Rev 8: 905-916.
36. Pricola KL, Kuhn NZ, Haleem-Smith H, Song Y, Tuan RS (2009) Interleukin-6 maintains bone marrow-derived mesenchymal stem cell stemness by an ERK1/2-dependent mechanism. J Cell Biochem 108: 577-588.
37. Zhang F, Tsai S, Kato K, Yamanouchi D, Wang C, et al. (2009) Transforming growth factor-beta promotes recruitment of bone marrow cells and bone marrow-derived mesenchymal stem cells through stimulation of MCP-1 production in vascular smooth muscle cells. J Biol Chem 284: 17564-17574.
38. Belema-Bedada F, Uchida S, Martire A, Kostin S, Braun T (2008) Efficient homing of multipotent adult mesenchymal stem cells depends on FROUNT-mediated clustering of CCR2. Cell Stem Cell 2:66-75.
39. Schmal H, Niemeyer P, Roesslein M, Hartl D, Loop T, et al. (2007) Comparison of cellular functionality of human mesenchymal stromal cells and PBMC. Cytotherapy 9: 69-79.
40. Mayer H, Bertram H, Lindenmaier W, Korff T, Weber H, et al. (2005) Vascular endothelial growth factor (VEGF-A) expression in human mesenchymal stem cells: autocrine and paracrine role on osteoblastic and endothelial differentiation. J Cell Biochem 95: 827-839. (Pubitemid 41420169)
41. Abarbanell AM, Coffey AC, Fehrenbacher JW, Beckman DJ, Herrmann JL, et al. (2009) Proinflammatory cytokine effects on mesenchymal stem cell therapy for the ischemic heart. Ann Thorac Surg 88:1036-1043.
42. Sezer O, Jakob C, Eucker J, Niemöller K, Gatz F, et al. (2001) Serum levels of the angiogenic cytokines basic fibroblast growth factor (bFGF), vascular endothelial growth factor (VEGF) and hepatocyte growth factor (HGF) in multiple myeloma. Eur J Haematol 66: 83-88. (Pubitemid 32154100)
43. Fiedler J, Etzel N, Brenner RE (2004) To go or not to go: Migration of human mesenchymal progenitor cells stimulated by isoforms of PDGF. J Cell Biochem 93: 990-998. (Pubitemid 44264152)
44. Ohnishi S, Sumiyoshi H, Kitamura S, Nagaya N (2007) Mesenchymal stem cells attenuate cardiac fibroblast proliferation and collagen synthesis through paracrine actions. FEBS Lett 581: 3961-3966. (Pubitemid 47212103)
45. Shen W, Park BW, Toms D, Li J (2012) Midkine promotes proliferation of primordial germ cells by inhibiting the expression of the deleted in azoospermia-like gene. Endocrinology 153: 3482-3492.
46. Shimomura T, Yoshida Y, Sakabe T, Ishii K, Gonda K, et al. (2007) Hepatic differentiation of human bone marrow-derived UE7T-13 cells: Effects of cytokines and CCN family gene expression. Hepatol Res 37: 1068-1079. (Pubitemid 350028334)
47. Corre J, Labat E, Espagnolle N, Hébraud B, Avet-Loiseau H, et al. (2012) Bioactivity and prognostic significance of growth differentiation factor GDF15 secreted by bone marrow mesenchymal stem cells in multiple myeloma. Cancer Res 72: 1395-1406.
48. Neuhuber B, Swanger SA, Howard L, Mackay A, Fischer I (2008) Effects of plating density and culture time on bone marrow stromal cell characteristics. Exp Hematol 36: 1176-1185.
49. Wagner W, Horn P, Castoldi M, Diehlmann A, Bork S, et al. (2008) Replicative senescence of mesenchymal stem cells: a continuous and organized process. PLoS One 3: e2213.
50. Colter DC, Class R, DiGirolamo CM, Prockop DJ (2000) Rapid expansion of recycling stem cells in cultures of plastic-adherent cells from human bone marrow. Proc Natl Acad Sci U S A 97: 3213-3218. (Pubitemid 30183281)
51. Zuk PA, Zhu M, Mizuno H, Huang J, Futrell JW, et al. (2001) Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Eng 7: 211-228. (Pubitemid 32295155)