Pharmacologically active C-19 diterpenoid alkaloids from the aerial parts of Aconitum laeve royle

Records of Natural Products

Volumn 8, Issue 2, 2014, Pages 83-92

  Begum, Seema ^a   Ali, Mumtaz ^a   Latif, Abdul ^a   Ahmad, Waqar ^a   Alam, Sultan ^a   Nisar, Muhammad ^a   Zeeshan, Muhammad ^b,d   Hassan Khan, Mahmud Tareq ^c   Shaheen, Farzana ^b   Ahmad, Manzoor ^a  

^a UNIVERSITY OF MALAKAND   (Pakistan)

^b UNIVERSITY OF KARACHI   (Pakistan)

^c UNIVERSITY OF TROMSØ   (Norway)

^d NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

Author keywords

Aconitum laeve royle; Anti inflammatory; Antioxidant; C19 diterpenoids alkaloids chemistry; Swatinine A; Swatinine B; Tyrosinase inhibitors

Indexed keywords

BUTYLATED HYDROXYANISOLE; CHASMANINE; DELVESTINE; DITERPENOID; FORESTICINE; INDOMETACIN; MONOPHENOL MONOOXYGENASE; NEOLINE; SWATININE A; SWATININE B; UNCLASSIFIED DRUG;

ACONITE; ACONITUM LAEVE; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; ENZYME INHIBITION; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR MULTIPLE QUANTUM COHERENCE; HUMAN; IN VITRO STUDY; MASS SPECTROMETRY; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

EID: 84896472346     PISSN: None     EISSN: 13076167     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. F. N. Dzakhangirov, M. N. Sultankhodzhaev, B. Tashkhdjaer and B. T. Salimov (1997). Diterpenoid alkaloids as a new class of antiarrhythmic agents. Structure-activity relationship, Chem. Nat. Comp. 33:22, 190.
2. M. H. Benn and J. M. Jacuno (1984). In: Alkaloids: Chemical and biological perspectives, Pelletier S. W., (Ed), Wiley, New York. 1, 153-209.
3. M. Muroyama and T. Mori (1993). European Patent Application EP-564648-A-1, Sanwa Shoyaku K.K.
4. J. M. Jacyno, J. S. Harwood, Nan-Horng Lin, J. E. Campbell, J. P. Sullivan and M. W (1996). Holladay. Lycaconitine Revisited: Partial Synthesis and Neuronal Nicotinic Acetylcholine Receptor Affinities, J. Nat. Prod. 59, 707-709.
5. N. G. Bisset (1981). Arrow poisons in China, Part II. Aconitum-botany, chemistry, and pharmacology, J. Ethnopharm. 4, 247.
6. K. S. Mhaskar, E. Blatter and J. F. Caius (2000). Indian Medicinal Plants. 1, 28.
7. T. Baytop (1984). Theraphy with Medicinal Plants in Turkey (Past and Present), Istanbul University, Publication No. 3255, 187.
8. U. Kolak, A. Türkekul, F. Özgökçe and A. Ulubelen (2005). Two new diterpenoid alkaloids from Aconitum cochleare, Pharmazie. 60, 953.
9. M. Ahmad, W. Ahmad, M. Ahmad, Obaidullah, M. Zeeshan and F. Shaheen (2008). Norditerpenoid alkaloids from the roots of Aconitum heterophyllum Wall with antibacterial activity, J. Enzy. Inhib. Med. Chem. 23:6, 1018-1022.
10. M. Nisar, Obaidullah, M. Ahmad, M. A. Lodhi, F. Shaheen and M. I. Choudhary (2009). New diterpenoid alkaloids from Aconitum heterophyllum Wall: Selective butyrylcholinestrase inhibitors, J. Enzy. Inhib. Med. Chem. 24:1, 47-51.
11. F. Shaheen, M. Ahmad, M. T. H. Khan, S. Jalil, A. Ejaz, M. N. Sultankhodjaev, M. Arfan, M. I. Choudhary and Atta-ur-Rahman (2005). Alkaloids of Aconitum laeve and their anti-inflammatory, antioxidant and tyrosinase inhibition activities, Phytochem. 66, 935-940.
12. F. Shaheen, M. Zeeshan, M. Ahmad, S. Anjum, S. Ali, H. K. Fun, M. I. Choudhary and Atta-ur-Rahman (2006). Norditerpenoid Alkaloids from Delphinium nordhagenii, J. Nat. Prod. 69, 823-825.
13. M. Shiino, Y. Watanabe and W. Umezawa (2001). Synthesis of Nsubstituted N-nitrosohydroxylamines as inhibitors of mushroom tyrosinase, Bio. Med. Chem. 9, 1233-1236.
14. M. A. Pathak and P. C. Joshi (1983). The nature and molecular basis of cutaneous photosensitivity reactions to psoralens and coal tar, J. Inves. Derm. 80, 66-68.
15. M. G. Hertog, E. J. Feskens, P. C. Hollman, M. B. Katan and D. Kromhout (1993). Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study, Lancet. 342, 1007-1011.
16. A. Moure, J. Cruz, D. Franco, J. M. Dominguez, J. Sineiro, H. Dominguez, M. J. Nunez and J. C. Parajo (2001). Natural antioxidants from residual sources, Food Chem. 72, 145-171.
17. P. C. Hollman and M. B. Katan (1999). Dietary flavonoids intake, health effects and bioavailability, Food Chem. Tox. 37, 937-942.
18. A. S. Meyer, M. Heinonen and E. N. Frankel (1998). Antioxidant interactions of catechin, cyanidin, caffeic acid, quercetin, and ellagic acid on human LDL oxidation, Food Chem. 61, 71-75.
19. E. J. Hunt, C. E. Lester, P. A. Lester and R. L. Tackett (2001). Effect of St. John's wort on free radical production, Life Sci. 69, 181-190.
20. D. Bagchi, M. Bagchi and S. J. Stohs (1997). Comparative in vitro oxygen radical scavenging ability of zinc methionine and selected zinc salts and antioxidants, Gen. Pharm. 28:1, 85-91.
21. An. S. Tan and M. V. Berridge (2000). Superoxide produced by activated neutrophils efficiently reduces the tetrazolium salt, WST-1 to produce a soluble formazan: a simple colorimetric assay for measuring respiratory burst activation and for screening anti-inflammatory agents, Immun. Methods. 238, 50.
22. S. W. Pelletier, C. S. Ying, B. S. Joshi and H. K. Desai (1984). The structures of forestine and foresticine, two new C19-diterpenoid alkaloids from Aconitum forrestii stapf, J. Nat. Prod. 47, 474.
23. S. A. Ross and S. W. Pelletier (1988). New synthetic esters of delphisine and neoline. Heterocycles. 27, 1381.
24. H. K. Desai, B. S. Joshi and S. W. Pelletier (1985). Two new diterpenoid alkaloids from Delphinium vestitum Wall, Heterocycles. 23, 2483.
25. S. W. Pelletier, W. H. De Camp and Z. Djarmati (1976). Proof of the structure of the diterpene alkaloid chasmanine: the crystal and molecular structure of chasmanine 14 α-benzoate hydrochloride, J. Chem. Soc. Chem. Commun. 253.
26. V. J. Hearing (1987). Methods in Enzymology, Academic Press, New York, 142, 154.
27. R. A. Siddiqui, D. English, Y. Cui, M. I. Marin, J. Wentlands and L. Akard (1995). Phorbal ester induced priming of superoxide generation by phosphatide acid-stimulated neutrophils and granule-free neutrophil cytoplasts, J. Leuk. Bio. 58, 189-195.
28. H. Daeseok, J. K. Seok, D. M. Kwang and S. R. Joon (1995). Measurement of superoxid dismutase like activity of natural antioxidant, Biosci. Biotech. Biochem. 59:5, 822.
29. A. A. Nishanov, M. N. Sultankhodzhaev, M. S. Yunusove and B. Tashkhodzhaev (1992). Alkaloids of Aconitum kirinense, Structure of akirine. Chem. Nat. Comp. 28:5, 466.
30. A. G. Gonzalez, G. de la Fuente and O. Mungufa (1983). 18-Methoxygadesin, a new diterpenoid alkaloid, Heterocycles. 20:3, 409-411.
31. A. G. Gonzalez, G. de la Fuente and O. Mungufa (1981). Structure of 18-hydroxy-14-O-methylgadesine a new diterpene alkaloid from Consolida orientalis, Tetr. Lett. 22:48, 4843-4844.
32. M. Shamma, P. Chinnasamy, G. A. Miana, A. Khan, M. Bashir, M. Salazar, P. Patil and J. Beal (1979). The alkaloids of Delphinium cashmirianum, J. Nat. Prod. 42, 615.
33. M. S. Yunusov, Ya. V. Rashkes and S. Yunusov (1972). Yu. Khim. Prir. Soedin. 8, 85.
34. S. W. Pelletier, N. V. Mody, R. H. F. In Manske and R. Rodrigo(1979) (Eds.): the Alkaloids, New York, Academic Press. 17.
35. Yu quan De and B. C. Das (1983). Alkaloids of Aconitum barbatum, Planta Medica. 49, 85.