Effects of life-long fluoride intake on bone measures of adolescents: A prospective cohort study

Journal of Dental Research

Volumn 93, Issue 4, 2014, Pages 353-359

  Levy, S M ^a,b   Warren, J J ^a   Phipps, K ^c   Letuchy, E ^b   Broffitt, B ^a   Eichenberger Gilmore, J ^a,b   Burns, T L ^b,d   Kavand, G ^a   Janz, K F ^b,e   Torner, J C ^b   Pauley, C A ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c Oral Health Research Consultant   (United States)

^d UNIVERSITY OF IOWA   (United States)

^e E11 SSH   (United States)

Author keywords

children; densitometry; dual energy x ray absorptiometry; longitudinal; observational study; skeleton

Indexed keywords

ANTICARIES AGENT; FLUORIDE; VITAMIN; VITAMIN D;

ADOLESCENT; BODY HEIGHT; BODY WEIGHT; BONE; BONE DENSITY; BONE DEVELOPMENT; CALCIUM INTAKE; CHILD; COHORT ANALYSIS; DENSITOMETRY; DRUG EFFECT; DUAL-ENERGY X-RAY ABSORPTIOMETRY; FEMALE; GROWTH; HUMAN; LONGITUDINAL; LONGITUDINAL STUDY; LUMBAR VERTEBRA; MALE; MOTOR ACTIVITY; OBSERVATIONAL STUDY; PELVIC GIRDLE; PHOTON ABSORPTIOMETRY; PROSPECTIVE STUDY; REVIEW; SKELETON;

CHILDREN; DENSITOMETRY; DUAL-ENERGY X-RAY ABSORPTIOMETRY; LONGITUDINAL; OBSERVATIONAL STUDY; SKELETON;

ABSORPTIOMETRY, PHOTON; ADOLESCENT; BODY HEIGHT; BODY WEIGHT; BONE AND BONES; BONE DENSITY; BONE DEVELOPMENT; CALCIUM, DIETARY; CARIOSTATIC AGENTS; COHORT STUDIES; FEMALE; FLUORIDES; GROWTH; HUMANS; LONGITUDINAL STUDIES; LUMBAR VERTEBRAE; MALE; MOTOR ACTIVITY; PELVIC BONES; PROSPECTIVE STUDIES; VITAMIN D; VITAMINS;

EID: 84896466136     PISSN: 00220345     EISSN: 15440591     Source Type: Journal    
DOI: 10.1177/0022034514520708     Document Type: Review

References (30)

1. Allolio B, Lehmann R. Drinking water fluoridation and bone. Exp Clin Endocrinol Diabetes. 1999 ; 107: 12-20
2. Arnold CM, Bailey DA, Faulkner RA, McKay HA, McCulloch RG. The effect of water fluoridation on the bone mineral density of young women. Can J Public Health. 1997 ; 88: 388-391
3. Bratteb LE, Samuelson G, Sandhagen B, Mallmin H, Lantz H, Sjöström L. Whole-body mineral measurements in Swedish adolescents at 17 years compared to 15 years of age. Acta Paediatr. 2002 ; 91: 1031-1038
4. CDC (2013). 2012 Water Fluoridation Statistics: Division of Oral Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention. URL accessed on 1/2/14 at: http://www.cdc.gov/ fluoridation/statistics/2012stats.htm.
5. Chachra D, Limeback H, Willett TL, Grynpas MD. The long-term effects of water fluoridation on the human skeleton. J Dent Res. 2010 ; 89: 1219-1223
6. Demos LL, Kazda H, Cicuttini FM, Sinclair MI, Fairley CK. Water fluoridation, osteoporosis, fractures: recent developments. Aust Dent J. 2001 ; 46: 80-87
7. Fratzl P, Roschger P, Eschberger J, Abendroth B, Klaushofer K. Abnormal bone mineralization after fluoride treatment in osteoporosis: a small-angle x-ray-scattering study. J Bone Miner Res. 1994 ; 9: 1541-1549
8. Grobler SR, Louw AJ, Chikte UM, Rossouw RJ, van W, Kotze TJ. The relationships between two different drinking water fluoride levels, dental fluorosis and bone mineral density of children. Open Dent J. 2009 ; 3: 48-54
9. Hillier S, Inskip H, Coggon D, Cooper C. Water fluoridation and osteoporotic fracture. Community Dent Health. 1996 ; 13: 63-68
10. Hillier S, Cooper C, Kellingray S, Russell G, Hughes H, Coggon D. Fluoride in drinking water and risk of hip fracture in the UK: a case-control study. Lancet. 2000 ; 355: 265-269
11. Jacobsen SJ, Goldberg J, Cooper C, Lockwood SA. The association between water fluoridation and hip fracture among white women and men aged 65 years and older. A national ecologic study. Ann Epidemiol. 1992 ; 2: 617-662
12. Janz KF, Medema-Johnson HC, Letuchy EM, Burns TL, Gilmore JM, Torner JC, et al. Subjective and objective measures of physical activity in relationship to bone mineral content during late childhood: the Iowa Bone Development Study. Br J Sports Med. 2008 ; 42: 658-663
13. Karagas MR, Baron JA, Barrett JA, Jacobsen SJ. Patterns of fracture among the United States elderly: geographic and fluoride effects. Ann Epidemiol. 1996 ; 6: 209-216
14. Kwon S, Janz KF, Burns TL, Levy SM. Effects of adiposity on physical activity in childhood: Iowa Bone Development Study. Med Sci Sports Exerc. 2011 ; 43: 443-448
15. Levy SM, Warren JJ, Davis CS, Kirchner HL, Kanellis MJ, Wefel JS. Patterns of fluoride intake from birth to 36 months. J Public Health Dent. 2001 ; 61: 70-77
16. Levy SM, Warren JJ, Broffitt B. Patterns of fluoride intake from 36 to 72 months of age. J Public Health Dent. 2003 ; 63: 211-220
17. Levy SM, Eichenberger-Gilmore J, Warren JJ, Letuchy E, Broffitt B, Marshall TA, et al. Association of fluoride intake with children's bone measures at age 11. Community Dent Oral Epidemiol. 2009 ; 37: 416-426
18. Marshall TA, Eichenberger-Gilmore JM, Broffitt B, Stumbo PJ, Levy SM. Relative validity of the Iowa Fluoride Study targeted nutrient semi-quantitative questionnaire and the block kids' food questionnaire for estimating beverage, calcium, and vitamin D intakes by children. J Am Diet Assoc. 2008 ; 108: 465-472
19. Mirwald RL, Baxter-Jones AD, Bailey DA, Beunen GP. An assessment of maturity from anthropometric measurements. Med Sci Sports Exerc. 2002 ; 34: 689-694
20. Park EY, Hwang SS, Kim JY, Cho SH. Effects of long-term fluoride in drinking water on risks of hip fracture of the elderly: an ecologic study based on database of hospitalization episodes. J Prev Med Public Health. 2008 ; 41: 147-152
21. Phipps KR, Orwoll ES, Mason JD, Cauley JA. Community water fluoridation, bone mineral density, and fractures: prospective study of effects in older women. BMJ. 2000 ; 321: 860-864
22. Søgaard CH, Mosekilde L, Richards A, Mosekilde L. Marked decrease in trabecular bone quality after five years of sodium fluoride therapy - assessed by biomechanical testing of iliac crest bone biopsies in osteoporotic patients. Bone. 1994 ; 15: 393-399
23. Washington, DC: National Academy Press ; 1997: 288-313.
24. Tanner JM 1962 ). Growth at adolescence. 2nd ed.Oxford: Blackwell Scientific. Oxford: Blackwell Scientific ; 1962 :
25. US Environmental Protection Agency (2010). Fluoride: dose-response analysis for non-cancer effects. Accessed on 12/23/2013 at: http://water.epa. gov/action/advisories/drinking/upload/Fluoride-dose-response.pdf.
26. Vestergaard P, Jorgensen NR, Schwarz P, Mosekilde L. Effects of treatment with fluoride on bone mineral density and fracture risk - a meta-analysis. Osteoporos Int. 2008 ; 19: 257-268
27. Videman T, Levälahti E, Battié MC, Simonen R, Vanninen E, Kaprio J. Heritability of BMD of femoral neck and lumbar spine: a multivariate twin study of Finnish men. J Bone Miner Res. 2007 ; 22: 1455-1462
28. Wagner H, Melhus H, Pedersen NL, Michaëlsson K. Genetic influence on bone phenotypes and body composition: a Swedish twin study. J Bone Miner Metab. 2013 ; 31: 681-689
29. Whitford GM. The metabolism and toxicity of fluoride. Monogr Oral Sci. 1989 ; 13: 1-160
30. Whitford GM. Fluoride metabolism and excretion in children. J Public Health Dent. 1999 ; 59: 224-228