Sour cherry (Prunus cerasus) seed extract increases heme oxygenase-1 expression and decreases proinflammatory signaling in peripheral blood human leukocytes from rheumatoid arthritis patients

International Immunopharmacology

Volumn 20, Issue 1, 2014, Pages 188-196

  Mahmoud, Fadia ^a   Haines, David ^b   Al Awadhi, Rana ^a   Dashti, Ali A ^a   Al Awadhi, Adel ^a   Ibrahim, Basel ^a   Al Zayer, Bashayer ^a   Juhasz, Bela ^b   Tosaki, Arpad ^b  

^a KUWAIT UNIVERSITY   (Kuwait)

^b UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

HO 1; IL 8; Peripheral blood; Rheumatoid arthritis; Sour cherry kernel; TNF

Indexed keywords

ANTIINFLAMMATORY AGENT; CD3 ANTIGEN; HEME OXYGENASE 1; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; PLANT EXTRACT; PRUNUS CERASUS EXTRACT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; HMOX1 PROTEIN, HUMAN; IL8 PROTEIN, HUMAN;

ADULT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CLINICAL ARTICLE; COCULTURE; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE MARKER; DOSE RESPONSE; DRUG SCREENING; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; LEUKOCYTE; LEUKOCYTE CULTURE; MIDDLE AGED; PATHOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SOUR CHERRY; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; CELL CULTURE; DRUG EFFECTS; IMMUNOLOGY; MONONUCLEAR CELL; PLANT SEED; PRUNUS;

ADULT; ANTIGENS, CD3; ARTHRITIS, RHEUMATOID; CELLS, CULTURED; FEMALE; HEME OXYGENASE-1; HUMANS; INTERLEUKIN-8; LEUKOCYTES, MONONUCLEAR; LIPOPOLYSACCHARIDES; MIDDLE AGED; PLANT EXTRACTS; PRUNUS; SEEDS; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84896449659     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2014.02.031     Document Type: Article

References (35)

1. V. Majithia, and S.A. Geraci Rheumatoid arthritis: diagnosis and management Am J Med 120 2007 936 939 (Pubitemid 47633476)
2. C. Monaco, E. Andreakos, S. Kiriakidis, M. Feldmann, and E. Paleolog T-cell-mediated signalling in immune, inflammatory and angiogenic processes: the cascade of events leading to inflammatory diseases Curr Drug Targets Inflamm Allergy 3 2004 35 42 (Pubitemid 38854888)
3. T. Monjardino, R. Lucas, and H. Barros Frequency of rheumatic diseases in Portugal: a systematic review Acta Reumatol Port 36 2011 336 363
4. C.A. Shourt, C.S. Crowson, S.E. Gabriel, and E.L. Matteson Orthopedic surgery among patients with rheumatoid arthritis 1980-2007: a population-based study focused on surgery rates, sex, and mortality J Rheumatol 39 2012 481 485
5. M. Pikwer, U. Bergstrom, J.A. Nilsson, L. Jacobsson, and C. Turesson Early menopause is an independent predictor of rheumatoid arthritis Ann Rheum Dis 71 2012 378 381
6. C. Deighton, R. O'Mahony, J. Tosh, C. Turner, and M. Rudolf Management of rheumatoid arthritis: summary of NICE guidance BMJ 338 2009 b702
7. T.G. Benedek Methotrexate: from its introduction to non-oncologic therapeutics to anti-TNF-alpha Clin Exp Rheumatol 28 2010 S3 S8
8. S. Rehart, I. Arnold, and M. Furst Conservative local therapy of inflammation of joints: local invasive forms of therapy Z Rheumatol 66 2007 382 387 (Pubitemid 47402410)
9. I.E. Lundberg, C. Grundtman, E. Larsson, and L. Klareskog Corticosteroids - from an idea to clinical use Best Pract Res Clin Rheumatol 18 2004 7 19 (Pubitemid 38324655)
10. H. Kaiser Cortisone therapy today Wien Klin Wochenschr 115 2003 6 21
11. G.S. Alarcon Methotrexate use in rheumatoid arthritis. A Clinician's perspective Immunopharmacology 47 2000 259 271 (Pubitemid 30394542)
12. I. Bak, A. Czompa, E. Csepanyi, B. Juhasz, H. Kalantari, and K. Najm et al. Evaluation of systemic and dermal toxicity and dermal photoprotection by sour cherry kernels Phytother Res 25 2011 1714 1720
13. M. Feldmann, F.M. Brennan, and R.N. Maini Role of cytokines in rheumatoid arthritis Annu Rev Immunol 14 1996 397 440 (Pubitemid 26130190)
14. S.J. Moon, M.K. Park, H.J. Oh, S.Y. Lee, S.K. Kwok, and M.L. Cho et al. Engagement of toll-like receptor 3 induces vascular endothelial growth factor and interleukin-8 in human rheumatoid synovial fibroblasts Korean J Intern Med 25 2010 429 435
15. R. Kokebie, R. Aggarwal, S. Lidder, A.A. Hakimiyan, D.C. Rueger, and J.A. Block et al. The role of synovial fluid markers of catabolism and anabolism in osteoarthritis, rheumatoid arthritis and asymptomatic organ donors Arthritis Res Ther 13 2011 R50
16. F.M. Cowan, C.A. Broomfield, M.P. Stojiljkovic, and W.J. Smith A review of multi-threat medical countermeasures against chemical warfare and terrorism Mil Med 169 2004 850 855 (Pubitemid 40797189)
17. B. Juhasz, A. Kertesz, J. Balla, G. Balla, Z. Szabo, and M. Bombicz et al. Cardioprotective effects of sour cherry seed extract (SCE) on the hypercholesterolemic rabbit heart Curr Pharm Des 2013 6896 6905
18. F.F. Mahmoud, R. Al-Awadhi, D.D. Haines, A. Dashti, H. Dashti, and E. Al-Ozairi et al. Sour cherry seed kernel extract increases heme oxygenase-1 expression and decreases representation of CD3 + TNF-alpha + and CD3+IL-8 + subpopulations in peripheral blood leukocyte cultures from type 2 diabetes patients Phytother Res 27 2013 767 774
19. D. Morse, and A.M. Choi Heme oxygenase-1: the "emerging molecule" has arrived Am J Respir Cell Mol Biol 27 2002 8 16 (Pubitemid 34657385)
20. D. Morse, and A.M. Choi Heme oxygenase-1: from bench to bedside Am J Respir Crit Care Med 172 2005 660 670 (Pubitemid 41324219)
21. D.D. Haines, I. Lekli, P. Teissier, I. Bak, and A. Tosaki Role of haeme oxygenase-1 in resolution of oxidative stress-related pathologies: focus on cardiovascular, lung, neurological and kidney disorders Acta Physiol (Oxf) 204 2012 487 501
22. F.C. Arnett, S.M. Edworthy, D.A. Bloch, D.J. McShane, J.F. Fries, and N.S. Cooper et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis Arthritis Rheum 31 1988 315 324 (Pubitemid 18091653)
23. T.T. Tang, Y. Song, Y.J. Ding, Y.H. Liao, X. Yu, and R. Du et al. Atorvastatin upregulates regulatory T cells and reduces clinical disease activity in patients with rheumatoid arthritis J Lipid Res 52 2011 1023 1032
24. I. Bak, I. Lekli, B. Juhasz, E. Varga, B. Varga, and R. Gesztelyi et al. Isolation and analysis of bioactive constituents of sour cherry (Prunus cerasus) seed kernel: an emerging functional food J Med Food 13 2010 905 910
25. F.F. Mahmoud, S.A. al-Harbi, M. McCabe, D.D. Haines, J.A. Burleson, and D.L. Kreutzer Abnormal lymphocyte surface antigen expression in peripheral blood of a Kuwaiti population Ann N Y Acad Sci 793 1996 498 503 (Pubitemid 26402630)
26. P.R. Antas, J.S. Sales, K.C. Pereira, E.B. Oliveira, K.S. Cunha, and E.N. Sarno et al. Patterns of intracellular cytokines in CD4 and CD8 T cells from patients with mycobacterial infections Braz J Med Biol Res 37 2004 1119 1129 (Pubitemid 39177419)
27. K. Conlon, A. Lloyd, U. Chattopadhyay, N. Lukacs, S. Kunkel, and T. Schall et al. CD8 + and CD45RA + human peripheral blood lymphocytes are potent sources of macrophage inflammatory protein 1 alpha, interleukin-8 and RANTES Eur J Immunol 25 1995 751 756
28. Y. Kirino, M. Takeno, S. Murakami, M. Kobayashi, H. Kobayashi, and K. Miura et al. Tumor necrosis factor alpha acceleration of inflammatory responses by down-regulating heme oxygenase 1 in human peripheral monocytes Arthritis Rheum 56 2007 464 475
29. H. Kobayashi, M. Takeno, T. Saito, Y. Takeda, Y. Kirino, and K. Noyori et al. Regulatory role of heme oxygenase 1 in inflammation of rheumatoid arthritis Arthritis Rheum 54 2006 1132 1142 (Pubitemid 43672926)
30. T. Minamino, H. Christou, C.M. Hsieh, Y. Liu, V. Dhawan, and N.G. Abraham et al. Targeted expression of heme oxygenase-1 prevents the pulmonary inflammatory and vascular responses to hypoxia Proc Natl Acad Sci U S A 98 2001 8798 8803 (Pubitemid 32678107)
31. I. Bak, I. Lekli, B. Juhasz, N. Nagy, E. Varga, and J. Varadi et al. Cardioprotective mechanisms of Prunus cerasus (sour cherry) seed extract against ischemia-reperfusion-induced damage in isolated rat hearts Am J Physiol Heart Circ Physiol 291 2006 H1329 H1336
32. M.E. Szabo, E. Gallyas, I. Bak, A. Rakotovao, F. Boucher, and J. de Leiris et al. Heme oxygenase-1-related carbon monoxide and flavonoids in ischemic/reperfused rat retina Invest Ophthalmol Vis Sci 45 2004 3727 3732 (Pubitemid 39298591)
33. K.D. Poss, and S. Tonegawa Reduced stress defense in heme oxygenase 1-deficient cells Proc Natl Acad Sci U S A 94 1997 10925 10930 (Pubitemid 27430837)
34. L.E. Otterbein, F.H. Bach, J. Alam, M. Soares, H. Tao Lu, and M. Wysk et al. Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway Nat Med 6 2000 422 428 (Pubitemid 30208159)
35. P.L. Hooper, and P.L. Hooper Inflammation, heat shock proteins, and type 2 diabetes Cell Stress Chaperones 14 2009 113 115