Electrospun aligned PHBV/collagen nanofibers as substrates for nerve tissue engineering

Biotechnology and Bioengineering

Volumn 110, Issue 10, 2013, Pages 2775-2784

  Prabhakaran, Molamma P ^a   Vatankhah, Elham ^a,b   Ramakrishna, Seeram ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b ISFAHAN UNIVERSITY OF TECHNOLOGY   (Iran)

Author keywords

Aligned nanofibers; Electrospinning; Nerve regeneration; Neurite; Orientation

Indexed keywords

BIOCOMPATIBILITY; CELL PROLIFERATION; CELLS; CRYSTAL ORIENTATION; ELECTROSPINNING; NANOFIBERS; NEURONS; SCAFFOLDS (BIOLOGY); SUBSTRATES;

ALIGNED NANOFIBERS; COMPOSITE SCAFFOLDS; CRUCIAL PARAMETERS; CULTURED NERVE CELLS; NERVE REGENERATION; NERVE TISSUE ENGINEERING; NEURITES; TOPOGRAPHICAL CUES;

TISSUE REGENERATION;

COLLAGEN; COPOLYMER; NANOFIBER; POLY(3 HYDROXYBUTYRATE CO 3 HYDROXYVALERATE); UNCLASSIFIED DRUG; POLY(3 HYDROXYBUTYRATE) CO (3 HYDROXYVALERATE); POLY(3-HYDROXYBUTYRATE)-CO-(3-HYDROXYVALERATE); POLYESTER; TISSUE SCAFFOLD;

ANIMAL CELL; ARTICLE; BIOCOMPATIBILITY; BIOMIMETICS; CELL PROLIFERATION ASSAY; CELL STRUCTURE; ELECTROSPINNING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; NERVE FIBER GROWTH; NERVE INJURY; NERVE REGENERATION; NERVOUS TISSUE; NEURITE; NONHUMAN; PC12 CELL LINE; TISSUE ENGINEERING; ALIGNED NANOFIBERS; ANIMAL; CELL PROLIFERATION; CHEMISTRY; CYTOLOGY; DRUG EFFECT; ELECTROCHEMICAL ANALYSIS; EQUIPMENT; MATERIALS TESTING; MECHANICAL STRESS; METHODOLOGY; NERVE CELL; ORIENTATION; PC12 CELL; PHYSIOLOGY; RAT; YOUNG MODULUS; DEVICES; DRUG EFFECTS; PROCEDURES; TISSUE SCAFFOLD;

ALIGNED NANOFIBERS; ELECTROSPINNING; NERVE REGENERATION; NEURITE; ORIENTATION;

ANIMALS; CELL PROLIFERATION; COLLAGEN; ELASTIC MODULUS; ELECTROCHEMICAL TECHNIQUES; MATERIALS TESTING; NANOFIBERS; NEURONS; PC12 CELLS; POLYESTERS; RATS; STRESS, MECHANICAL; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84896407136     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.24937     Document Type: Article

References (26)

1. Amass W, Amass A, Tighe B. 1998. A review of biodegradable polymers: Uses, current developments in the synthesis and characterization of biodegradable polyesters, blends of biodegradable polymers and recent advances in biodegradation studies. Polym Int 47:89-144.
2. Chen W, Tong YW. 2012. PHBV microspheres as neural tissue engineering scaffold support neuronal cell growth and axon-dendrite polarization. Acta Biom 8:540-548.
3. Compagnone NA. 2008. Treatments for spinal cord injury: Is there hope in neurosteroids? J Steroid Biochem Mol Biol 109:307-313.
4. Cooper A, Bhattarai N, Zhang M. 2011. Fabrication and cellular compatibility of aligned chitosan-PCL fibers for nerve tissue regeneration. Carb Poly 85:149-156.
5. Dai Y, Yuan ZG, Jack K, Keller J. 2007. Production of targeted poly(3-hydroxyalkanoates) copolymers by glycogen accumulating organisms using acetate as sole carbon source. J Biotechnol 129:489-497.
6. Dickson BJ. 2002. Molecular mechanisms of axon guidance. Science 298:1959-1964.
7. Gertz CC, Leach MK, Birrell LK, Martin DC, Feldman EL, Corey JM. 2010. Accelerated neuritogenesis and maturation of primary spinal motor neurons in response to nanofibers. Dev Neurobiol 70:589-603.
8. Ghasemi-Mobarakeh L, Prabhakaran MP, Morshed M, Nasr-Esfahani MH, Ramakrishna S. 2008. Electrospun poly(3-caprolactone)/gelatin nanofibrous scaffolds for nerve tissue engineering. Biomaterials 29:4532-4539.
9. Goodman CS. 1996. Mechanisms and molecules that control growth cone guidance. Annu Rev Neurosci 19:341-377.
10. Hirono T, Torimitsu K, Kawana A, Fukuda J. 1988. Recognition of artificial microstructures by sensory nerve fibers in culture. Brain Res 446:189-194.
11. Keynes R. 1997. Surround repulsion of spinal sensory axons in higher vertebrate embryos. Neuron 18:889-897.
12. Lariviere RC, Julien JP. 2004. Functions of intermediate filaments in neuronaldevelopment and disease. J Neurobiol 581:131-148.
13. Lee CH, Shin HJ, Cho IH, Kang YM, Kim IA, Park KD, Shin JW. 2005. Nanofiber alignment and direction of mechanical strain affect the ECM production of human ACL fibroblast. Biomaterials 26:1261-1270.
14. Lee JY, Bashur CA, Gomez N, Goldstein AS, Schmidt CE. 2010. Enhanced polarization of embryonic hippocampal neurons on micron scale electrospun fibers. J Biomed Mater Res A 92A:1398-1406.
15. Más Estellés J, Vidaurre A, Meseguer Duẽnas J, Castilla Cortázar I. 2008. Physical characterization of polycaprolactone scaffolds. J Mater Sci Mater Med 19:189-195.
16. Rangappa N, Romero A, Nelson KD, Eberhart RC, Smith GM. 2001. Laminin-coated poly(l-lactide) filaments induce robust neurite growth while providing directional orientation. J Biomed Mater Res 51:625-634.
17. Rizvi AH, Wasserman AJ, Zazanis G, Silver FH. 1991. Evaluation of peripheral nerve regeneration in the presence of longitudinally aligned collagen fibers. Cell Mater 1:279-289.
18. Rosso F, Marino G, Giordano A, Barbarisi M, Parmeggiani D, Barbarisi A. 2005. Smart materials as scaffolds for tissue engineering. J Cell Physiol 203:465-470.
19. Schnell E, Klinkhammer K, Balzer S, Brook G, Klee D, Dalton P, Mey J. 2007. Guidance of glial cell migration and axonal growth on electrospun nanofibers of poly-epsilon-caprolactone and a collagen/poly-epsilon-caprolactone blend. Biomaterials 28:3012-3025.
20. Slavin S, Kurkalli BGS, Karussis D. 2008. The potential use of adult stem cells for the treatment of multiple sclerosis and other neurodegenerative disorders. Clin Neurol Neurosurg 110:943-946.
21. Strasberg SR, Mackinnon SE, Genden EM, Bain JR, Purcell CM, Hunter DA, Hay JB. 1996. Long-segment nerve allograft regeneration in the sheep model. J Reconstr Microsurg 12:529-537.
22. Suwantong O, Waleetorncheepsawat S, Sanchavanakit N, Pavasant P, Cheepsunthorn P, Bunaprasert T, Supaphol P. 2007. In vitro biocompatibility of electrospun poly(3-hydroxybutyrate) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) fiber mats. Int J Biol Macromol 40:217-223.
23. Tessier-Lavigne M, Goodman CS. 1996. The molecular biology of axon guidance. Science 274:1123-1133.
24. Thomas V, Zhang X, Vohra YK. 2009. A biomimetic tubular scaffold with spatially designed nanofibers of protein/PDS bioblends. Biotechnol Bioeng 104:1025-1033.
25. Xu C, Inai R, Kotaki M, Ramakrishna S. 2004. Electrospun nanofiber fabrication as synthetic extracellular matrix and its potential for vascular tissue engineering. Tissue Eng 10:1160-1168.
26. Yucel D, Kose GT, Hasirci V. 2010. Polyester based nerve guidance conduit design. Biomaterials 31:1596-1603.