메뉴 건너뛰기




Volumn 6, Issue 3, 2014, Pages 210-219

A proteomic evaluation of the effects of the pharmaceuticals diclofenac and gemfibrozil on marine mussels (Mytilus spp.): Evidence for chronic sublethal effects on stress-response proteins

Author keywords

Biomarkers; Diclofenac; Gemfibrozil; Mytilus spp; Proteomics

Indexed keywords

DRUG PRODUCTS; ELECTROPHORESIS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; MOLECULAR BIOLOGY; MOLLUSCS; OXIDATIVE STRESS; PROTEINS;

EID: 84896397013     PISSN: 19427603     EISSN: 19427611     Source Type: Journal    
DOI: 10.1002/dta.1463     Document Type: Article
Times cited : (59)

References (52)
  • 1
    • 85153154705 scopus 로고    scopus 로고
    • EEA., EU Environment Agency, Copenhagen,
    • EEA. Pharmaceuticals in the Environment, EU Environment Agency, Copenhagen, Vol. 1, 2010, pp. 34.
    • (2010) Pharmaceuticals in the Environment , vol.1 , pp. 34
  • 2
    • 72049110796 scopus 로고    scopus 로고
    • Ecotoxicological aspects related to the presence of pharmaceuticals in the aquatic environment
    • L.H.M.L.M. Santos, A. Fachini, A. Pena, C. Delerue-Matos, M.C. Montenegro. Ecotoxicological aspects related to the presence of pharmaceuticals in the aquatic environment. J. Hazard. Mater. 2010, 175, 45.
    • (2010) J. Hazard. Mater. , vol.175 , pp. 45
    • Santos, L.H.1    Fachini, A.2    Pena, A.3    Delerue-Matos, C.4    Montenegro, M.C.5
  • 3
    • 0033383635 scopus 로고    scopus 로고
    • Pharmaceuticals and personal care products in the environment: Agents of subtle change?
    • C.G. Daughton, T.A. Ternes. Pharmaceuticals and personal care products in the environment: Agents of subtle change? Environ. Health Perspect. 1999, 107, 907.
    • (1999) Environ. Health Perspect. , vol.107 , pp. 907
    • Daughton, C.G.1    Ternes, T.A.2
  • 6
    • 42649092530 scopus 로고    scopus 로고
    • An LC-MS method for the determination of pharmaceutical compounds in wastewater treatment plant influent and effluent samples
    • C. Lacey, G. McMahon, J. Bones, L. Barron, A. Morrissey, J.M. Tobin. An LC-MS method for the determination of pharmaceutical compounds in wastewater treatment plant influent and effluent samples. Talanta 2008, 75, 1089.
    • (2008) Talanta , vol.75 , pp. 1089
    • Lacey, C.1    McMahon, G.2    Bones, J.3    Barron, L.4    Morrissey, A.5    Tobin, J.M.6
  • 7
    • 0345305721 scopus 로고    scopus 로고
    • Distribution of acidic and neutral drugs in surface waters near sewage treatment plants in the lower Great Lakes, Canada
    • C.D. Metcalfe, X.S. Miao, B.G. Koenig, J. Struger. Distribution of acidic and neutral drugs in surface waters near sewage treatment plants in the lower Great Lakes, Canada. Environ. Toxicol. Chem. 2003, 22, 2881.
    • (2003) Environ. Toxicol. Chem. , vol.22 , pp. 2881
    • Metcalfe, C.D.1    Miao, X.S.2    Koenig, B.G.3    Struger, J.4
  • 8
    • 77953592687 scopus 로고    scopus 로고
    • Diclofenac: An update on its mechanism of action and safety profile
    • T.J. Gan. Diclofenac: An update on its mechanism of action and safety profile. Curr. Med. Res. Opin. 2010, 26, 1715.
    • (2010) Curr. Med. Res. Opin. , vol.26 , pp. 1715
    • Gan, T.J.1
  • 10
    • 24944514554 scopus 로고    scopus 로고
    • Water-borne diclofenac affects kidney and gill integrity and selected immune parameters in brown trout (Salmo trutta Fario)
    • B. Hoeger, B. Köllner, D.R. Dietrich, B. Hitzfeld. Water-borne diclofenac affects kidney and gill integrity and selected immune parameters in brown trout (Salmo trutta Fario). Aquat. Toxicol. 2005, 75, 53.
    • (2005) Aquat. Toxicol. , vol.75 , pp. 53
    • Hoeger, B.1    Köllner, B.2    Dietrich, D.R.3    Hitzfeld, B.4
  • 11
    • 2442543527 scopus 로고    scopus 로고
    • Toxic effects of the non-steroidal anti-inflammatory drug diclofenac. Part I: histopathological alterations and bioaccumulation in rainbow trout
    • J. Schwaiger, H. Ferling, U. Mallow, H. Wintermayr, R.D. Negele. Toxic effects of the non-steroidal anti-inflammatory drug diclofenac. Part I: histopathological alterations and bioaccumulation in rainbow trout. Aquat. Toxicol. 2004, 68, 141.
    • (2004) Aquat. Toxicol. , vol.68 , pp. 141
    • Schwaiger, J.1    Ferling, H.2    Mallow, U.3    Wintermayr, H.4    Negele, R.D.5
  • 12
    • 2442535152 scopus 로고    scopus 로고
    • Toxic effects of the non-steroidal anti-inflammatory drug diclofenac. Part II: Cytological effects in liver, kidney, gills and intestine of rainbow trout (Oncorhynchus mykiss)
    • R. Triebskorn, H. Casper, A. Heyd, R. Eikemper, H.R. Köhler, J. Schwaiger. Toxic effects of the non-steroidal anti-inflammatory drug diclofenac. Part II: Cytological effects in liver, kidney, gills and intestine of rainbow trout (Oncorhynchus mykiss). Aquat. Toxicol. 2004, 68, 151.
    • (2004) Aquat. Toxicol. , vol.68 , pp. 151
    • Triebskorn, R.1    Casper, H.2    Heyd, A.3    Eikemper, R.4    Köhler, H.R.5    Schwaiger, J.6
  • 14
    • 33750692763 scopus 로고    scopus 로고
    • Waterborne gemfibrozil challenges the hepatic antioxidant defense system and down-regulates peroxisome proliferator-activated receptor beta (PPARβ) mRNA levels in male goldfish (Crassius auratus)
    • C. Mimeault, V.L. Trudeau, T.W. Moon. Waterborne gemfibrozil challenges the hepatic antioxidant defense system and down-regulates peroxisome proliferator-activated receptor beta (PPARβ) mRNA levels in male goldfish (Crassius auratus). Toxicology 2006 228, 140.
    • (2006) Toxicology , vol.228 , pp. 140
    • Mimeault, C.1    Trudeau, V.L.2    Moon, T.W.3
  • 15
    • 18844432589 scopus 로고    scopus 로고
    • The human lipid regulator, gemfibrozil bioconcentrates and reduces testosterone in goldfish, Carassius auratus
    • C. Mimeault, A.J. Woodhouse, X.S. Miao, C.D. Metcalfe, T.W. Moon, V.L. Trudeau. The human lipid regulator, gemfibrozil bioconcentrates and reduces testosterone in goldfish, Carassius auratus. Aquat. Toxicol. 2005, 73, 44.
    • (2005) Aquat. Toxicol. , vol.73 , pp. 44
    • Mimeault, C.1    Woodhouse, A.J.2    Miao, X.S.3    Metcalfe, C.D.4    Moon, T.W.5    Trudeau, V.L.6
  • 16
    • 79959353160 scopus 로고    scopus 로고
    • Effects of the pharmaceuticals gemfibrozil and diclofenac on the marine mussel (Mytilus spp.) and their comparison with standardized toxicity tests
    • W. Schmidt, K. O'Rourke, R. Hernan, B. Quinn. Effects of the pharmaceuticals gemfibrozil and diclofenac on the marine mussel (Mytilus spp.) and their comparison with standardized toxicity tests. Mar. Pollut. Bull. 2011, 62, 1389.
    • (2011) Mar. Pollut. Bull. , vol.62 , pp. 1389
    • Schmidt, W.1    O'Rourke, K.2    Hernan, R.3    Quinn, B.4
  • 17
    • 34548391493 scopus 로고    scopus 로고
    • Proteomic applications in ecotoxicology
    • T. Monsinjon, T. Knigge. Proteomic applications in ecotoxicology. Proteomics 2007, 7, 2997.
    • (2007) Proteomics , vol.7 , pp. 2997
    • Monsinjon, T.1    Knigge, T.2
  • 19
    • 0033751418 scopus 로고    scopus 로고
    • Protein expression signatures identified in Mytilus edulis exposed to PCBs, copper and salinity stress
    • J.L. Shepard, B. Olsson, M. Tedengren, B.P. Bradley. Protein expression signatures identified in Mytilus edulis exposed to PCBs, copper and salinity stress. Mar. Environ. Res. 2000, 50, 337.
    • (2000) Mar. Environ. Res. , vol.50 , pp. 337
    • Shepard, J.L.1    Olsson, B.2    Tedengren, M.3    Bradley, B.P.4
  • 20
    • 34250836448 scopus 로고    scopus 로고
    • Proteomics-based method for the assessment of marine pollution using liquid chromatography coupled with two-dimensional electrophoresis
    • H. Amelina, I. Apraiz, W. Sun, S. Cristobal. Proteomics-based method for the assessment of marine pollution using liquid chromatography coupled with two-dimensional electrophoresis. J. Proteome Res. 2007, 6, 2094.
    • (2007) J. Proteome Res. , vol.6 , pp. 2094
    • Amelina, H.1    Apraiz, I.2    Sun, W.3    Cristobal, S.4
  • 23
    • 0042861622 scopus 로고    scopus 로고
    • Changes in protein expression profiles in bivalve molluscs (Chamaelea gallina) exposed to four model environmental pollutant
    • M.J. Rodríguez-Ortega, B.E. Grøsvik, A. Rodríguez-Ariza, A. Goyr, J. López-Barea. Changes in protein expression profiles in bivalve molluscs (Chamaelea gallina) exposed to four model environmental pollutant. Proteomics 2003, 3, 1535.
    • (2003) Proteomics , vol.3 , pp. 1535
    • Rodríguez-Ortega, M.J.1    Grøsvik, B.E.2    Rodríguez-Ariza, A.3    Goyr, A.4    López-Barea, J.5
  • 24
    • 33750586534 scopus 로고    scopus 로고
    • Utility of proteomics to assess pollutant response of clams from the Doñana bank of Guadalquivir Estuary (SW Spain)
    • A. Romero-Ruiz, M. Carrascal, J. Alhama, J.L. Gómez-Ariza, J. Abian, J. López-Barea. Utility of proteomics to assess pollutant response of clams from the Doñana bank of Guadalquivir Estuary (SW Spain). Proteomics 2006, 6, S245.
    • (2006) Proteomics , vol.6
    • Romero-Ruiz, A.1    Carrascal, M.2    Alhama, J.3    Gómez-Ariza, J.L.4    Abian, J.5    López-Barea, J.6
  • 25
    • 85153160324 scopus 로고    scopus 로고
    • An assessment of two decades of contaminant monitoring in the nation's coastal zone, Technical Memorandum 74. NOAA Silver Spring, MD
    • K.L. Kimbrough, W.E. Johnson, G.C. Lauenstein, J.D. Christensen, D.A. Apeti. An assessment of two decades of contaminant monitoring in the nation's coastal zone, Technical Memorandum 74. NOAA Silver Spring, MD, 2008, pp. 1-105.
    • (2008) , pp. 1-105
    • Kimbrough, K.L.1    Johnson, W.E.2    Lauenstein, G.C.3    Christensen, J.D.4    Apeti, D.A.5
  • 26
    • 0026310142 scopus 로고
    • Mussels as biological indicators of pollution
    • A. Viarengo, L. Canesi. Mussels as biological indicators of pollution. Aquaculture 1991, 94, 225.
    • (1991) Aquaculture , vol.94 , pp. 225
    • Viarengo, A.1    Canesi, L.2
  • 27
    • 33846477335 scopus 로고    scopus 로고
    • Genetic structure of hybrid mussel populations in the West of Ireland: Two hypotheses revisited
    • B. Coghlan, E. Gosling. Genetic structure of hybrid mussel populations in the West of Ireland: Two hypotheses revisited. Mar. Biol. 2007, 150, 841.
    • (2007) Mar. Biol. , vol.150 , pp. 841
    • Coghlan, B.1    Gosling, E.2
  • 28
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • M.M. Bradford. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72, 248.
    • (1976) Anal. Biochem. , vol.72 , pp. 248
    • Bradford, M.M.1
  • 30
    • 0001740365 scopus 로고
    • Evaluation of lipid peroxidation in lipids and biological membranes
    • in, Eds: K. Snell, B. Mullock). IRL Press, Washington, USA
    • E.D. Wills. Evaluation of lipid peroxidation in lipids and biological membranes, in Biochemical Toxicology: A Practical Approach, (Eds: K. Snell, B. Mullock). IRL Press, Washington, USA, 1987.
    • (1987) Biochemical Toxicology: A Practical Approach
    • Wills, E.D.1
  • 31
    • 0023899205 scopus 로고
    • DNA precipitation assay: A rapid and simple method for detecting DNA damage in mammalian cells
    • P. Olive. DNA precipitation assay: A rapid and simple method for detecting DNA damage in mammalian cells. Environ. Mol. Mutagen. 1988, 11, 487.
    • (1988) Environ. Mol. Mutagen. , vol.11 , pp. 487
    • Olive, P.1
  • 32
    • 0037146488 scopus 로고    scopus 로고
    • Highly sensitive and fast protein detection with coomassie brilliant blue in sodium dodecyl sulfate-polyacrylamide gel electrophoresis
    • D. Kang, Y.S. Gho, M. Suh, C. Kang. Highly sensitive and fast protein detection with coomassie brilliant blue in sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Bull. Korean Chem. Soc. 2002, 23, 1511.
    • (2002) Bull. Korean Chem. Soc. , vol.23 , pp. 1511
    • Kang, D.1    Gho, Y.S.2    Suh, M.3    Kang, C.4
  • 33
    • 84896400448 scopus 로고    scopus 로고
    • Review of biomarkers and new techniques for in situ aquatic studies with bivalves
    • in, Eds: K.C. Thompson, K. Wadhia, A. Loibner). Blackwell Publishing Ltd, Oxford
    • F. Gagné, C. Blaise. Review of biomarkers and new techniques for in situ aquatic studies with bivalves, in Environmental Toxicity Testing, (Eds: K.C. Thompson, K. Wadhia, A. Loibner). Blackwell Publishing Ltd, Oxford, 2005, pp. 408.
    • (2005) Environmental Toxicity Testing , pp. 408
    • Gagné, F.1    Blaise, C.2
  • 34
    • 84865405253 scopus 로고    scopus 로고
    • The effect of shore location on biomarker expression in wild Mytilus spp. and its comparison with long line cultivated mussels
    • W. Schmidt, T. O'Shea, B. Quinn. The effect of shore location on biomarker expression in wild Mytilus spp. and its comparison with long line cultivated mussels. Mar. Environ. Res. 2012, 80, 70.
    • (2012) Mar. Environ. Res. , vol.80 , pp. 70
    • Schmidt, W.1    O'Shea, T.2    Quinn, B.3
  • 36
    • 84870879546 scopus 로고    scopus 로고
    • Pharmaceuticals in biota in the aquatic environment: Analytical methods and environmental implications
    • B. Huerta, S. Rodríguez-Mozaz, D. Barceló. Pharmaceuticals in biota in the aquatic environment: Analytical methods and environmental implications. Anal. Bioanal. Chem. 2012, 404, 2611.
    • (2012) Anal. Bioanal. Chem. , vol.404 , pp. 2611
    • Huerta, B.1    Rodríguez-Mozaz, S.2    Barceló, D.3
  • 37
    • 0037290663 scopus 로고    scopus 로고
    • Fish bioaccumulation and biomarkers in environmental risk assessment: A review
    • R. van der Oost, J. Beyer, N.P.E. Vermeulen. Fish bioaccumulation and biomarkers in environmental risk assessment: A review. Environ. Toxicol. Pharmacol. 2003, 13, 57.
    • (2003) Environ. Toxicol. Pharmacol. , vol.13 , pp. 57
    • van der Oost, R.1    Beyer, J.2    Vermeulen, N.P.E.3
  • 38
    • 84863845787 scopus 로고    scopus 로고
    • Proteomic research in bivalves. Towards the identification of molecular markers of aquatic pollution
    • A. Campos, S. Tedesco, V. Vasconcelos, S. Cristobal. Proteomic research in bivalves. Towards the identification of molecular markers of aquatic pollution. J. Proteomics 2012, 75, 4346.
    • (2012) J. Proteomics , vol.75 , pp. 4346
    • Campos, A.1    Tedesco, S.2    Vasconcelos, V.3    Cristobal, S.4
  • 40
    • 80052356804 scopus 로고    scopus 로고
    • A model of oxidative stress management: Moderation of carbohydrate metabolizing enzymes in SOD1-Null Drosophila melanogaster
    • K. Bernard, T. Parkes, T. Merritt. A model of oxidative stress management: Moderation of carbohydrate metabolizing enzymes in SOD1-Null Drosophila melanogaster. PLoS One 2011, 6, e24518.
    • (2011) PLoS One , vol.6
    • Bernard, K.1    Parkes, T.2    Merritt, T.3
  • 42
    • 67650726518 scopus 로고    scopus 로고
    • Alcohol dehydrogenase gene expression in Chironomus riparius exposed to di(2-ethylhexyl) phthalate
    • K. Park, I.-S. Kwak. Alcohol dehydrogenase gene expression in Chironomus riparius exposed to di(2-ethylhexyl) phthalate. Comp. Biochem. Physiol. C 2009, 150, 361.
    • (2009) Comp. Biochem. Physiol. C , vol.150 , pp. 361
    • Park, K.1    Kwak, I.-S.2
  • 43
    • 33846500763 scopus 로고    scopus 로고
    • Temperature-dependent effects of cadmium and purine nucleotides on mitochondrial aconitase from marine ecotherm, Crassostrea virginica: A role of temperature in oxidative stress and allosteric enzyme regulation
    • A.A. Cherkasov, R.A. Overton, E. Sokolov, I.M. Sokolova. Temperature-dependent effects of cadmium and purine nucleotides on mitochondrial aconitase from marine ecotherm, Crassostrea virginica: A role of temperature in oxidative stress and allosteric enzyme regulation. J. Exp. Biol. 2007, 210, 46.
    • (2007) J. Exp. Biol. , vol.210 , pp. 46
    • Cherkasov, A.A.1    Overton, R.A.2    Sokolov, E.3    Sokolova, I.M.4
  • 45
    • 0032926319 scopus 로고    scopus 로고
    • Peptidyl-prolyl cis-trans isomerase, a superfamily of ubiquitous folding catalysts
    • S.F. Göthel, M.A. Marahiel. Peptidyl-prolyl cis-trans isomerase, a superfamily of ubiquitous folding catalysts. Cell. Mol. Life Sci. 1999, 55, 423.
    • (1999) Cell. Mol. Life Sci. , vol.55 , pp. 423
    • Göthel, S.F.1    Marahiel, M.A.2
  • 46
    • 0033393804 scopus 로고    scopus 로고
    • Cyclophilins and their possible role in the stress response
    • L. Andreeva, R. Heads, C.J. Green. Cyclophilins and their possible role in the stress response. Int. J. Exp. Pathol. 1999, 80, 305.
    • (1999) Int. J. Exp. Pathol. , vol.80 , pp. 305
    • Andreeva, L.1    Heads, R.2    Green, C.J.3
  • 47
    • 80053330193 scopus 로고    scopus 로고
    • Haemocyte protein expression profiling of scallop Chlamys farreri response to acute viral necrosis (AVNV) infection
    • G. Chen, C. Zhang, C. Li, C. Wang, Z. Xu, P. Yan. Haemocyte protein expression profiling of scallop Chlamys farreri response to acute viral necrosis (AVNV) infection. Dev. Comp. Immunol. 2011, 35, 1135.
    • (2011) Dev. Comp. Immunol. , vol.35 , pp. 1135
    • Chen, G.1    Zhang, C.2    Li, C.3    Wang, C.4    Xu, Z.5    Yan, P.6
  • 49
    • 84860357017 scopus 로고    scopus 로고
    • New insights in flat oyster Ostrea edulis resistance against the parasite Bonamia ostreae
    • B. Morga, T. Renault, N. Faury, I. Arzul. New insights in flat oyster Ostrea edulis resistance against the parasite Bonamia ostreae. Fish Shellfish Immunol. 2012, 32, 958.
    • (2012) Fish Shellfish Immunol. , vol.32 , pp. 958
    • Morga, B.1    Renault, T.2    Faury, N.3    Arzul, I.4
  • 50
    • 0032937597 scopus 로고    scopus 로고
    • A new family of growth factors produced by the fat body and active on Drosophila imaginal disc cells
    • K. Kawamura, T. Shibata, O. Saget, D. Peel, P.J. Bryant. A new family of growth factors produced by the fat body and active on Drosophila imaginal disc cells. Development 1999, 126, 211.
    • (1999) Development , vol.126 , pp. 211
    • Kawamura, K.1    Shibata, T.2    Saget, O.3    Peel, D.4    Bryant, P.J.5
  • 51
    • 0027505001 scopus 로고
    • Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family
    • B.E. Hakala, C. White, A.D. Recklies. Human cartilage gp-39, a major secretory product of articular chondrocytes and synovial cells, is a mammalian member of a chitinase protein family. J. Biol. Chem. 1993, 268, 25803.
    • (1993) J. Biol. Chem. , vol.268 , pp. 25803
    • Hakala, B.E.1    White, C.2    Recklies, A.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.