Quantification of curcumin, demethoxycurcumin, and bisdemethoxycurcumin in rodent brain by UHPLC/ESI-Q-TOF-MS/MS after intra-nasal administration of curcuminoids loaded PNIPAM nanoparticles

Drug Testing and Analysis

Volumn 6, Issue 3, 2014, Pages 257-267

  Ahmad, Niyaz ^a   Warsi, Musarrat Husain ^a   Iqbal, Zeenat ^a   Samim, Mohd ^b   Ahmad, Farhan Jalees ^a  

^a HAMDARD UNIVERSITY   (India)

^b HAMDARD UNIVERSITY   (India)

Author keywords

Bisdemethoxycurcumin; Curcumin; Demethoxycurcumin; PNIPAM nanoparticles; UHPLC MS MS ESI Q TOF

Indexed keywords

ELECTROSPRAY IONIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; RATS; SOLVENT EXTRACTION;

ANALYTES; BISDEMETHOXYCURCUMIN; BRAIN HOMOGENATES; CURCUMIN; DEMETHOXYCURCUMIN; PNIPAM NANOPARTICLE; RATS BRAIN; U-HPLC-MS; UHPLC-MS/MS-ESI-Q-TOF; WISTAR RAT;

NANOPARTICLES;

2 PROPANOL; ACETIC ACID ETHYL ESTER; ACETONITRILE; ACRYLIC ACID DERIVATIVE; AMMONIUM FORMATE; CHLOROFORM; CURCUMIN; CURCUMINOID; DEMETHOXYCURCUMIN; DIDEMETHOXYCURCUMIN; FORMIC ACID; METHANOL; NANOPARTICLE; NIMESULIDE; POLYMERIC N ISOPROPYL ACRYL AMIDE VINYL PYRILIDONE ACRYLIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN HOMOGENATE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG STABILITY; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; EX VIVO STUDY; FLOW RATE; FREEZE THAWING; IN VIVO STUDY; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIQUID LIQUID EXTRACTION; MEASUREMENT ACCURACY; MEASUREMENT PRECISION; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL NOISE RATIO; TANDEM MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

BISDEMETHOXYCURCUMIN; CURCUMIN; DEMETHOXYCURCUMIN; PNIPAM NANOPARTICLES; UHPLC-MS/MS-ESI-Q-TOF;

ACRYLIC RESINS; ADMINISTRATION, INTRANASAL; ANIMALS; ANTINEOPLASTIC AGENTS; BRAIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CURCUMIN; LIMIT OF DETECTION; NANOPARTICLES; RATS; RATS, WISTAR; TANDEM MASS SPECTROMETRY;

EID: 84896393186     PISSN: 19427603     EISSN: 19427611     Source Type: Journal    
DOI: 10.1002/dta.1472     Document Type: Article

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