Characterization of a complex CYP2D6 genotype that caused an AmpliChip CYP450 Test® no-call in the clinical setting

Clinical Chemistry and Laboratory Medicine

Volumn 52, Issue 6, 2014, Pages 799-807

  Gaedigk, Andrea ^a   Riffel, Amanda K ^a   Berrocal, Belén García ^b   Solaesa, Virginia García ^b   Dávila, Ignacio ^b   Isidoro García, María ^b  

^a CHILDREN S MERCY HOSPITAL   (United States)

^b HOSPITAL UNIVERSITARIO DE SALAMANCA   (Spain)

Author keywords

AmpliChip CYP450 test; CYP2D6; Cytochrome CYP450; Genotyping; Pharmacogenetics

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL; CYTOCHROME P450 2C19; CYTOCHROME P450 2D6; NONSTEROID ANTIINFLAMMATORY AGENT;

AGED; ALLELE; ARTICLE; ASPIRIN TRIAD; ASTHMA; BRONCHOCONSTRICTION; CASE REPORT; COMPUTER MODEL; COPY NUMBER VARIATION; DNA SEQUENCE; DRUG HYPERSENSITIVITY; DRUG INDUCED DISEASE; DRUG METABOLISM; FUNCTION TEST KIT; GENE DOSAGE; GENE DUPLICATION; GENE LOCUS; GENOTYPE; HUMAN; HYBRID GENE; INTRON; LOW DRUG DOSE; MALE; NOSE POLYP; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; THROMBOCYTE AGGREGATION; COMPUTER SIMULATION; GENETICS; LABORATORY DIAGNOSIS; PROCEDURES;

AGED; ALLELES; COMPUTER SIMULATION; CYTOCHROME P-450 CYP2D6; DNA COPY NUMBER VARIATIONS; DNA MUTATIONAL ANALYSIS; FALSE NEGATIVE REACTIONS; GENETIC LOCI; GENOTYPE; HUMANS; MALE;

EID: 84896376967     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/cclm-2013-0943     Document Type: Article

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