Consequences of tributyltin chloride induced stress in Leydig cells: An ex-vivo approach

Environmental Toxicology and Pharmacology

Volumn 37, Issue 2, 2014, Pages 850-860

  Mitra, Sumonto ^a   Srivastava, Ankit ^a   Khanna, Smita ^a   Khandelwal, Shashi ^a  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

Author keywords

Leydig; Oxidative stress; Steroidogenesis; Testosterone; Tributyltin chloride

Indexed keywords

3BETA HYDROXY DELTA5 STEROID DEHYDROGENASE; ACETYLCYSTEINE; CALCIUM ION; CYCLOSPORIN A; EGTAZIC ACID; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GLUTATHIONE; JANUS KINASE 1; JANUS KINASE 2; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHYCOCYANIN; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; RUTHENIUM RED; STEROIDOGENIC ACUTE REGULATORY PROTEIN; TESTOSTERONE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRANSLOCATOR PROTEIN; TRIBUTYLTIN CHLORIDE; UNCLASSIFIED DRUG; 3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; 4 AMINOBUTYRIC ACID A RECEPTOR; BAX PROTEIN, RAT; BZRP PROTEIN, RAT; CALCIUM; CARRIER PROTEIN; ENDOCRINE DISRUPTOR; MITOGEN ACTIVATED PROTEIN KINASE; NFE2L2 PROTEIN, RAT; ORGANOTIN COMPOUND; PHOSPHOPROTEIN; POLLUTANT; TRANSCRIPTION FACTOR NRF2; TRIBUTYLTIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM HOMEOSTASIS; CELL ASSAY; CELL STRESS; CELL SURVIVAL; CELL VIABILITY; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; CONTROLLED STUDY; CYTOTOXICITY TEST; DNA FRAGMENTATION; ENZYME PHOSPHORYLATION; EX VIVO STUDY; LEYDIG CELL; MALE; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; NUCLEAR CONDENSATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REDOX STRESS; TESTOSTERONE SYNTHESIS; TOXICITY TESTING; WISTAR RAT; ANIMAL; CELL CULTURE; DRUG EFFECTS; LIPID PEROXIDATION; METABOLISM; OXIDATIVE STRESS; POLLUTANT; TOXICITY;

3-HYDROXYSTEROID DEHYDROGENASES; ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CALCIUM; CARRIER PROTEINS; CELL SURVIVAL; CELLS, CULTURED; ENDOCRINE DISRUPTORS; ENVIRONMENTAL POLLUTANTS; GLUTATHIONE; LEYDIG CELLS; LIPID PEROXIDATION; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOGEN-ACTIVATED PROTEIN KINASES; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PHOSPHOPROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RECEPTORS, GABA-A; TESTOSTERONE; TRIALKYLTIN COMPOUNDS;

EID: 84896371091     PISSN: 13826689     EISSN: 18727077     Source Type: Journal    
DOI: 10.1016/j.etap.2014.02.018     Document Type: Article

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