-
1
-
-
63449139456
-
Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
-
Aller S., Yu J., Ward A., Weng Y., Chittaboina S., Zhuo R., Harrell P., Trinh Y., Zhang Q., Urbatsch I., Chang G. 2009. Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding. Science. Vol. 323(5922) 1718-1722.
-
(2009)
Science
, vol.323
, Issue.5922
, pp. 1718-1722
-
-
Aller, S.1
Yu, J.2
Ward, A.3
Weng, Y.4
Chittaboina, S.5
Zhuo, R.6
Harrell, P.7
Trinh, Y.8
Zhang, Q.9
Urbatsch, I.10
Chang, G.11
-
2
-
-
0344825356
-
P-glycoprotein: From genomics to mechanism
-
Ambudkar S.V., Kimchi-Sarfaty C, Sauna Z.E., Gottesman M.M. 2003. P-glycoprotein: from genomics to mechanism. Oncogene. 22(47):7468-7485.
-
(2003)
Oncogene
, vol.22
, Issue.47
, pp. 7468-7485
-
-
Ambudkar, S.V.1
Kimchi-Sarfaty, C.2
Sauna, Z.E.3
Gottesman, M.M.4
-
3
-
-
33947646506
-
Flavonoids, Chemistry, biochemistry and applications
-
Chapter 9, Taylor and Francis Group, LLC. USA
-
Andersen O. M., Markham K.R. 2006. Flavonoids, Chemistry, biochemistry and applications. Chapter 9. Flavonoid-Protein Interactions. Taylor and Francis Group, LLC. USA.
-
(2006)
Flavonoid-Protein Interactions
-
-
Andersen, O.M.1
Markham, K.R.2
-
4
-
-
0030589989
-
Steroid transport, accumulation, and antagonism of P-Glycoprotein in multidrug-resistant cells
-
Barnes K.M., Dickstein B., Cutler G.B., Fojo T., Bates S.E. 1996. Steroid transport, accumulation, and antagonism of P-Glycoprotein in multidrug-resistant cells. Biochemistry. 35, 4820-4827.
-
(1996)
Biochemistry
, vol.35
, pp. 4820-4827
-
-
Barnes, K.M.1
Dickstein, B.2
Cutler, G.B.3
Fojo, T.4
Bates, S.E.5
-
5
-
-
0032497591
-
Halogenated chalcones with high-affinity binding to P-glycoprotein: Potential modulators of multidrug resistance
-
Bois F., Beney C., Boumendjel A., Mariotte A.M., Conseil G., Di Pietro A. 1998. Halogenated chalcones with high-affinity binding to P-glycoprotein: potential modulators of multidrug resistance. J Med Chem. 41(21):4161-4.
-
(1998)
J Med Chem
, vol.41
, Issue.21
, pp. 4161-4164
-
-
Bois, F.1
Beney, C.2
Boumendjel, A.3
Mariotte, A.M.4
Conseil, G.5
Di Pietro, A.6
-
6
-
-
0035825368
-
B-ring substituted 5,7-dihydroxyflavonols with high-affinity binding to P-glycoprotein responsible for cell multidrug resistance
-
Boumendjel A., Bois F., Beney C., Mariotte A.M., Conseil G., Di Pietro A. 2001. B-ring substituted 5,7-dihydroxyflavonols with high-affinity binding to P-glycoprotein responsible for cell multidrug resistance. Bioorg Med Chem Lett. 11(1):75-77.
-
(2001)
Bioorg Med Chem Lett
, vol.11
, Issue.1
, pp. 75-77
-
-
Boumendjel, A.1
Bois, F.2
Beney, C.3
Mariotte, A.M.4
Conseil, G.5
Di Pietro, A.6
-
7
-
-
0036720280
-
Recent advances in the discovery of flavonoids and analogs with high-affinity binding to P-glycoprotein responsible for cancer cell multidrug resistance
-
Boumendjel A., Di Pietro A., Dumontet C., Barron D. 2002. Recent advances in the discovery of flavonoids and analogs with high-affinity binding to P-glycoprotein responsible for cancer cell multidrug resistance. Med Res Rev.22(5), 512-29.
-
(2002)
Med Res Rev
, vol.22
, Issue.5
, pp. 512-529
-
-
Boumendjel, A.1
Di Pietro, A.2
Dumontet, C.3
Barron, D.4
-
8
-
-
79952779478
-
A Novel Approach for Predicting P-glycoprotein (ABCB1) Inhibition Using Molecular Interaction Fields
-
Broccatelli F., Carosati E., Neri A., Frosini M, Goracci L, Oprea T.I., Cruciania G. 2011. A Novel Approach for Predicting P-glycoprotein (ABCB1) Inhibition Using Molecular Interaction Fields. J Med Chem. 54(6): 1740-1751.
-
(2011)
J Med Chem
, vol.54
, Issue.6
, pp. 1740-1751
-
-
Broccatelli, F.1
Carosati, E.2
Neri, A.3
Frosini, M.4
Goracci, L.5
Oprea, T.I.6
Cruciania, G.7
-
9
-
-
0031060647
-
Inhibition of drug transport by genistein in multidrug-resistant cells expressing P-glycoprotein
-
Castro A.F., Altenberg G.A. 1997. Inhibition of drug transport by genistein in multidrug-resistant cells expressing P-glycoprotein. Biochem Pharmacol. 53(1):89-93.
-
(1997)
Biochem Pharmacol
, vol.53
, Issue.1
, pp. 89-93
-
-
Castro, A.F.1
Altenberg, G.A.2
-
10
-
-
0035282638
-
C-Isoprenylation of flavonoids enhances binding affinity toward P-glycoprotein and modulation of cancer cell chemoresistance
-
Comte G., Daskiewicz J.B., Bayet C., Conseil G., Viornery-Vanier A., Dumontet C., Di Pietro A., Barron D. 2001. C-Isoprenylation of flavonoids enhances binding affinity toward P-glycoprotein and modulation of cancer cell chemoresistance. J Med Chem. 44(5):763-8.
-
(2001)
J Med Chem
, vol.44
, Issue.5
, pp. 763-768
-
-
Comte, G.1
Daskiewicz, J.B.2
Bayet, C.3
Conseil, G.4
Viornery-Vanier, A.5
Dumontet, C.6
Di Pietro, A.7
Barron, D.8
-
11
-
-
0032544087
-
Flavonoids: A class of modulators with bifunctional interactions at vicinal ATP-and steroid-binding sites on mouse P-glycoprotein
-
Conseil G., Baubichon-Cortay H., Dayan G., Jault J.M., Barron D., Di Pietro A. 1998. Flavonoids: a class of modulators with bifunctional interactions at vicinal ATP-and steroid-binding sites on mouse P-glycoprotein. Proc Natl Acad Sci USA. 95, 9831-6.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9831-9836
-
-
Conseil, G.1
Baubichon-Cortay, H.2
Dayan, G.3
Jault, J.M.4
Barron, D.5
Di Pietro, A.6
-
12
-
-
0035964385
-
Sequence Requirements of the ATP-Binding Site within the C-Terminal Nucleotide-Binding Domain of Mouse P-Glycoprotein: Structure-Activity Relationships for flavonoid binding
-
de Wet H., McIntosh DB., Conseil G., Baubichon-Cortay H., Krell T., Jault J.M., et al. 2001. Sequence Requirements of the ATP-Binding Site within the C-Terminal Nucleotide-Binding Domain of Mouse P-Glycoprotein: Structure-Activity Relationships for flavonoid binding. Biochemistry. 40, 10382-10391.
-
(2001)
Biochemistry
, vol.40
, pp. 10382-10391
-
-
de Wet, H.1
McIntosh, D.B.2
Conseil, G.3
Baubichon-Cortay, H.4
Krell, T.5
Jault, J.M.6
-
13
-
-
18344390872
-
Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein
-
Ekins S., Kim R.B., Leake B.F., Dantzig A.H., Schuetz E.G., Lan L.B., Yasuda K., Shepard R.L., Winter M.A., Schuetz J.D., Wikel J.H., Wrighton S.A. 2002. Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein. Molecular Pharmacology. 61, 964-973.
-
(2002)
Molecular Pharmacology
, vol.61
, pp. 964-973
-
-
Ekins, S.1
Kim, R.B.2
Leake, B.F.3
Dantzig, A.H.4
Schuetz, E.G.5
Lan, L.B.6
Yasuda, K.7
Shepard, R.L.8
Winter, M.A.9
Schuetz, J.D.10
Wikel, J.H.11
Wrighton, S.A.12
-
14
-
-
33644672481
-
Quantification and characterization of P-glycoprotein-substrate interactions
-
Gatlik-Landwojtowicz E, Äänismaa P, Seelig A. 2006. Quantification and characterization of P-glycoprotein-substrate interactions. Biochemistry. 45:3020-32.
-
(2006)
Biochemistry
, vol.45
, pp. 3020-3032
-
-
Gatlik-Landwojtowicz, E.1
Äänismaa, P.2
Seelig, A.3
-
15
-
-
0027218689
-
Biochemistry of multidrug resistance mediated by the multidrug transporter
-
Gottesman M.M., Pastan I. 1993. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem. 62:385-427.
-
(1993)
Annu Rev Biochem
, vol.62
, pp. 385-427
-
-
Gottesman, M.M.1
Pastan, I.2
-
16
-
-
73649111071
-
Understanding polyspecificity of multidrug ABC transporters: Closing in on the gaps in ABCB1
-
Gutmann D, Ward A, Urbatsch I, Chang G, Veen H. 2010. Understanding polyspecificity of multidrug ABC transporters: closing in on the gaps in ABCB1. Trends in biochemical sciences. Volume 35 (1), 36-42.
-
(2010)
Trends In Biochemical Sciences
, vol.35
, Issue.1
, pp. 36-42
-
-
Gutmann, D.1
Ward, A.2
Urbatsch, I.3
Chang, G.4
Veen, H.5
-
17
-
-
0027380245
-
Oestrogenic and pregnancy interceptomy efficiency of a flavonoid mixture from grangea-maderaspatana poir (Artemisia maderaspatana) in the mouse
-
Jain S., Sareen V., Narula A. 1993. Oestrogenic and pregnancy interceptomy efficiency of a flavonoid mixture from grangea-maderaspatana poir (Artemisia maderaspatana) in the mouse. Phytother Res. 7. 381-383.
-
(1993)
Phytother Res
, vol.7
, pp. 381-383
-
-
Jain, S.1
Sareen, V.2
Narula, A.3
-
18
-
-
0037196568
-
Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols
-
Jodoin J., Demeule M., Beliveau R. Inhibition of the multidrug resistance P-glycoprotein activity by green tea polyphenols. Biochim Biophys Acta. 1542(1/3):149-159.
-
Biochim Biophys Acta
, vol.1542
, Issue.1-3
, pp. 149-159
-
-
Jodoin, J.1
Demeule, M.2
Beliveau, R.3
-
19
-
-
0002241549
-
Biological properties of flavonoids pertaining to inflammation
-
Manthey J.A. 2000. Biological properties of flavonoids pertaining to inflammation. Microcirculation. 7, S29-S34.
-
(2000)
Microcirculation
, vol.7
-
-
Manthey, J.A.1
-
20
-
-
67650084777
-
Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP, and MRP2 among registered drugs
-
Matsson P., Pedersen J.M., Norinder U., Bergström C.A.S., Artursson P. 2009. Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP, and MRP2 among registered drugs. Pharmaceutical Research, Vol 26(8) 1816-1831.
-
(2009)
Pharmaceutical Research
, vol.26
, Issue.8
, pp. 1816-1831
-
-
Matsson, P.1
Pedersen, J.M.2
Norinder, U.3
Bergström, C.A.S.4
Artursson, P.5
-
21
-
-
0011438031
-
Naringenin, apigenin and genistein are weak estrogens, which bind to the estrogen receptor and elicit estrogen-induced response. Antimutatagenic and anticarcinogenic effects
-
Mitcher L. A., Tekkepalli H., Waner P.B.B., Kuo S., Kuo S., Shanhel D.M., Stewart G. 1982. Naringenin, apigenin and genistein are weak estrogens, which bind to the estrogen receptor and elicit estrogen-induced response. Antimutatagenic and anticarcinogenic effects. Mutant Res. 267. 229-241.
-
(1982)
Mutant Res
, vol.267
, pp. 229-241
-
-
Mitcher, L.A.1
Tekkepalli, H.2
Waner, P.B.B.3
Kuo, S.4
Kuo, S.5
Shanhel, D.M.6
Stewart, G.7
-
22
-
-
33744902318
-
Interaction of transported drugs with the lipid bilayer and P-glycoprotein through a solvation exchange mechanism
-
Omote H, Al-Shawi MK. 2006. Interaction of transported drugs with the lipid bilayer and P-glycoprotein through a solvation exchange mechanism. Biophys J. 90:4046-59.
-
(2006)
Biophys J
, vol.90
, pp. 4046-4059
-
-
Omote, H.1
Al-Shawi, M.K.2
-
23
-
-
0035827426
-
Natural and synthetic benzophenones: Interaction with the cytosolic binding domain of P-glycoprotein
-
Rancon S, Chaboud A, Darbour N, Comte G, Bayet C, Simon PN, Raynaud J, Di Pietro A, Cabalion P, Barron D. 2001. Natural and synthetic benzophenones: interaction with the cytosolic binding domain of P-glycoprotein. Phytochemistry. 57(4):553-7.
-
(2001)
Phytochemistry
, vol.57
, Issue.4
, pp. 553-557
-
-
Rancon, S.1
Chaboud, A.2
Darbour, N.3
Comte, G.4
Bayet, C.5
Simon, P.N.6
Raynaud, J.7
Di Pietro, A.8
Cabalion, P.9
Barron, D.10
-
24
-
-
0025149148
-
Wagonin, 5,7-dihydroxy-8-methoxy-flavone as oestrogenic and anti-implantational agent in the rat
-
Singh P., Jain S., Bhala M., Goyal R.B., Jayaprokash D., Lohiya N.K. 1990. Wagonin, 5,7-dihydroxy-8-methoxy-flavone as oestrogenic and anti-implantational agent in the rat. Phytother Res. 4. 86-89.
-
(1990)
Phytother Res
, vol.4
, pp. 86-89
-
-
Singh, P.1
Jain, S.2
Bhala, M.3
Goyal, R.B.4
Jayaprokash, D.5
Lohiya, N.K.6
-
25
-
-
52049089562
-
Flavonoids: Modulators of brain function?
-
Spencer J. P. E. Flavonoids: modulators of brain function? 2008. British Journal of Nutrition 99, ES60-ES77.
-
(2008)
British Journal of Nutrition
, vol.99
-
-
Spencer, J.P.E.1
-
26
-
-
0033979106
-
Genistein supplementation and estrogen replacement therapy improve endothelial dysfunction induced by ovariectomy in rats
-
Squadrito F., Altavilla D., Squadrito G., Saitta A., Cucinotta D., Minutoli L., Deodato B., Ferlito M., Campo G.m., Bova A., Caputi A.P. 2000. Genistein supplementation and estrogen replacement therapy improve endothelial dysfunction induced by ovariectomy in rats. Cardiovasc Res. 45. 454-462.
-
(2000)
Cardiovasc Res
, vol.45
, pp. 454-462
-
-
Squadrito, F.1
Altavilla, D.2
Squadrito, G.3
Saitta, A.4
Cucinotta, D.5
Minutoli, L.6
Deodato, B.7
Ferlito, M.8
Campo, G.M.9
Bova, A.10
Caputi, A.P.11
-
28
-
-
0037371275
-
Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport
-
Zhang S., Morris M.E. 2003. Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport. J Pharmacol Exp Ther. 304(3):1258-67.
-
(2003)
J Pharmacol Exp Ther
, vol.304
, Issue.3
, pp. 1258-1267
-
-
Zhang, S.1
Morris, M.E.2
|