Ultrasensitive opto-microfluidic immunosensor integrating gold nanoparticle-enhanced chemiluminescence and highly stable organic photodetector

Journal of Biomedical Optics

Volumn 19, Issue 3, 2014, Pages

  Pires, Nuno Miguel Matos ^a   Dong, Tao ^a  

^a UNIVERSITY OF SOUTH EASTERN NORWAY   (Norway)

Author keywords

cancer diagnostics; chemiluminescent immunoassay; gold nanoparticles; integrated microfluidics; organic photodiode

Indexed keywords

CHEMILUMINESCENCE; FLUIDIC DEVICES; GOLD; IMMUNOSENSORS; METAL NANOPARTICLES; PHOTODETECTORS; PHOTONS;

CANCER DIAGNOSTICS; CHEMILUMINESCENT IMMUNOASSAYS; GOLD NANOPARTICLES; INTEGRATED MICROFLUIDICS; ORGANIC PHOTODIODES;

MICROFLUIDICS;

GOLD; METAL NANOPARTICLE;

ARTICLE; CHEMICAL MODEL; CHEMISTRY; EQUIPMENT; FLUORESCENCE IMAGING; IMMUNOASSAY; LIMIT OF DETECTION; LUMINESCENCE; MICROFLUIDIC ANALYSIS;

GOLD; IMMUNOASSAY; LIMIT OF DETECTION; LUMINESCENT MEASUREMENTS; METAL NANOPARTICLES; MICROFLUIDIC ANALYTICAL TECHNIQUES; MODELS, CHEMICAL; OPTICAL IMAGING;

EID: 84896361197     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.JBO.19.3.030504     Document Type: Article

References (12)

1. J. Ozhikandathil and M. Packirisamy, "Silica-on-silicon waveguide integrated polydimethylsiloxane lab-on-a-chip for quantum dot fluorescence bio-detection, " J. Biomed. Opt. 17(1), 017006 (2012).
2. X. Zhao and T. Dong, "Multifunctional sample preparation kit and on-chip quantitative nucleic acid sequence-based amplification tests for microbial detection, " Anal. Chem. 84(20), 8541-8548 (2012).
3. J. R. Wojciechowski et al., "Organic photodiodes for biosensors miniaturization, " Anal. Chem. 81(9), 3455-3461 (2009).
4. N. M. M. Pires and T. Dong, "A cascade-like silicon filter for improved recovery of oocysts from environmental waters, " Environ. Technol. 35(6), 781-790 (2014).
5. V. Charwat et al., "Standardization of microfluidic cell cultures using integrated organic photodiodes and electrode arrays, " Lab Chip 13(5), 785-797 (2013).
6. R. Ishimatsu et al., "An organic thin film photodiode as a portable photodetector for the detection of alkylphenol polyethoxylates by a flow fluorescence-immunoassay on magnetic microbeads in a micro-channel, " Talanta 117, 139-145 (2013).
7. X. Gong et al., "High-detectivity polymer photodetectors with spectral response from 300 nm to 1450 nm, " Science 325(5948), 1665-1667 (2009).
8. M. Yang et al., "Gold nanoparticle-based enhanced chemiluminescence immunosensor for detection of Staphylococcal Enterotoxin B (SEB) in food, " Int. J. Food Microbiol. 133(3), 265-271 (2009).
9. N. M. M. Pires et al., "Integrated optical microfluidic biosensor using a polycarbazole photodetector for point-of-care detection of hormonal compounds, " J. Biomed. Opt. 18(9), 097001 (2013).
10. A. J. Heeger, "Semiconducting polymers: the third generation, " Chem. Soc. Rev. 39(7), 2354-2371 (2010).
11. S. Yu et al., "17-Beta-estradiol induces neoplastic transformation in prostatic epithelial cells, " Cancer Lett. 304(1), 8-20 (2011).
12. G. Lu et al., "Influence of the nanoscale structure of gold thin films upon peroxidase-induced chemiluminescence, " App. Phys. Lett. 88(2), 023903 (2006).