-
1
-
-
4043141580
-
Loss of apolipoprotein E receptor LR11 in Alzheimer disease
-
C. R. Scherzer, K. Offe, M. Gearing, H. D. Rees, G. Fang, C. J. Heilman, C. Schaller, H. Bujo, A. I. Levey, J. J. Lah, Loss of apolipoprotein E receptor LR11 in Alzheimer disease. Arch. Neurol. 61, 1200-1205 (2004).
-
(2004)
Arch. Neurol.
, vol.61
, pp. 1200-1205
-
-
Scherzer, C.R.1
Offe, K.2
Gearing, M.3
Rees, H.D.4
Fang, G.5
Heilman, C.J.6
Schaller, C.7
Bujo, H.8
Levey, A.I.9
Lah, J.J.10
-
2
-
-
84896360551
-
Lysosomal sorting of amyloid-β by the SORLA receptor is impaired by a familial Alzheimer's disease mutation
-
S. Caglayan, S. Takagi-Niidome, F. Liao, A.-S. Carlo, V. Schmidt, T. Burgert, Y. Kitago, E.-M. Füchtbauer, A. Füchtbauer, D. M. Holtzman, J. Takagi, T. E. Willnow, Lysosomal sorting of amyloid-β by the SORLA receptor is impaired by a familial Alzheimer's disease mutation. Sci. Transl. Med. 6, 223ra20 (2014).
-
(2014)
Sci. Transl. Med.
, vol.6
-
-
Caglayan, S.1
Takagi-Niidome, S.2
Liao, F.3
Carlo, A.-S.4
Schmidt, V.5
Burgert, T.6
Kitago, Y.7
Füchtbauer, E.-M.8
Füchtbauer, A.9
Holtzman, D.M.10
Takagi, J.11
Willnow, T.E.12
-
3
-
-
56549111118
-
VPS10P-domain receptors - Regulators of neuronal viability and function
-
T. E. Willnow, C. M. Petersen, A. Nykjaer, VPS10P-domain receptors - Regulators of neuronal viability and function. Nat. Rev. Neurosci. 9, 899-909 (2008).
-
(2008)
Nat. Rev. Neurosci.
, vol.9
, pp. 899-909
-
-
Willnow, T.E.1
Petersen, C.M.2
Nykjaer, A.3
-
4
-
-
26444607532
-
Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein
-
O. M. Andersen, J. Reiche, V. Schmidt, M. Gotthardt, R. Spoelgen, J. Behlke, C. A. von Arnim, T. Breiderhoff, P. Jansen, X. Wu, K. R. Bales, R. Cappai, C. L. Masters, J. Gliemann, E. J. Mufson, B. T. Hyman, S. M. Paul, A. Nykjaer, T. E. Willnow, Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein. Proc. Natl. Acad. Sci. U.S.A. 102, 13461-13466 (2005).
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 13461-13466
-
-
Andersen, O.M.1
Reiche, J.2
Schmidt, V.3
Gotthardt, M.4
Spoelgen, R.5
Behlke, J.6
Von Arnim, C.A.7
Breiderhoff, T.8
Jansen, P.9
Wu, X.10
Bales, K.R.11
Cappai, R.12
Masters, C.L.13
Gliemann, J.14
Mufson, E.J.15
Hyman, B.T.16
Paul, S.M.17
Nykjaer, A.18
Willnow, T.E.19
-
5
-
-
58149373433
-
Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: Evidence for a proximal role in Alzheimer's disease
-
S. E. Dodson, O. M. Andersen, V. Karmali, J. J. Fritz, D. Cheng, J. Peng, A. I. Levey, T. E. Willnow, J. J. Lah, Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: Evidence for a proximal role in Alzheimer's disease. J. Neurosci. 28, 12877-12886 (2008).
-
(2008)
J. Neurosci.
, vol.28
, pp. 12877-12886
-
-
Dodson, S.E.1
Andersen, O.M.2
Karmali, V.3
Fritz, J.J.4
Cheng, D.5
Peng, J.6
Levey, A.I.7
Willnow, T.E.8
Lah, J.J.9
-
6
-
-
33846613222
-
The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease
-
E. Rogaeva, Y. Meng, J. H. Lee, Y. Gu, T. Kawarai, F. Zou, T. Katayama, C. T. Baldwin, R. Cheng, H. Hasegawa, F. Chen, N. Shibata, K. L. Lunetta, R. Pardossi-Piquard, C. Bohm, Y. Wakutani, L. A. Cupples, K. T. Cuenco, R. C. Green, L. Pinessi, I. Rainero, S. Sorbi, A. Bruni, R. Duara, R. P. Friedland, R. Inzelberg, W. Hampe, H. Bujo, Y. Q. Song, O. M. Andersen, T. E. Willnow, N. Graff -Radford, R. C. Petersen, D. Dickson, S. D. Der, P. E. Fraser, G. Schmitt-Ulms, S. Younkin, R. Mayeux, L. A. Farrer, P. St. George-Hyslop, The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease. Nat. Genet. 39, 168-177 (2007).
-
(2007)
Nat. Genet.
, vol.39
, pp. 168-177
-
-
Rogaeva, E.1
Meng, Y.2
Lee, J.H.3
Gu, Y.4
Kawarai, T.5
Zou, F.6
Katayama, T.7
Baldwin, C.T.8
Cheng, R.9
Hasegawa, H.10
Chen, F.11
Shibata, N.12
Lunetta, K.L.13
Pardossi-Piquard, R.14
Bohm, C.15
Wakutani, Y.16
Cupples, L.A.17
Cuenco, K.T.18
Green, R.C.19
Pinessi, L.20
Rainero, I.21
Sorbi, S.22
Bruni, A.23
Duara, R.24
Friedland, R.P.25
Inzelberg, R.26
Hampe, W.27
Bujo, H.28
Song, Y.Q.29
Andersen, O.M.30
Willnow, T.E.31
Graff -Radford, N.32
Petersen, R.C.33
Dickson, D.34
Der, S.D.35
Fraser, P.E.36
Schmitt-Ulms, G.37
Younkin, S.38
Mayeux, R.39
Farrer, L.A.40
St George-Hyslop, P.41
more..
-
7
-
-
32544435097
-
The lipoprotein receptor LR11 regulates amyloid β production and amyloid precursor protein traffi c in endosomal compartments
-
K. Offe, S. E. Dodson, J. T. Shoemaker, J. J. Fritz, M. Gearing, A. I. Levey, J. J. Lah, The lipoprotein receptor LR11 regulates amyloid β production and amyloid precursor protein traffi c in endosomal compartments. J. Neurosci. 26, 1596-1603 (2006).
-
(2006)
J. Neurosci.
, vol.26
, pp. 1596-1603
-
-
Offe, K.1
Dodson, S.E.2
Shoemaker, J.T.3
Fritz, J.J.4
Gearing, M.5
Levey, A.I.6
Lah, J.J.7
-
8
-
-
84855356440
-
Quantitative modelling of amyloidogenic processing and its infl uence by SORLA in Alzheimer's disease
-
V. Schmidt, K. Baum, A. Lao, K. Rateitschak, Y. Schmitz, A. Teichmann, B. Wiesner, C. M. Petersen, A. Nykjaer, J. Wolf, O. Wolkenhauer, T. E. Willnow, Quantitative modelling of amyloidogenic processing and its infl uence by SORLA in Alzheimer's disease. EMBO J. 31, 187-200 (2012).
-
(2012)
EMBO J.
, vol.31
, pp. 187-200
-
-
Schmidt, V.1
Baum, K.2
Lao, A.3
Rateitschak, K.4
Schmitz, Y.5
Teichmann, A.6
Wiesner, B.7
Petersen, C.M.8
Nykjaer, A.9
Wolf, J.10
Wolkenhauer, O.11
Willnow, T.E.12
-
9
-
-
84863934372
-
GGA1-mediated endocytic traffi c of LR11/SorLA alters APP intracellular distribution and amyloid-β production
-
J. H. Herskowitz, K. Offe, A. Deshpande, R. A. Kahn, A. I. Levey, J. J. Lah, GGA1-mediated endocytic traffi c of LR11/SorLA alters APP intracellular distribution and amyloid-β production. Mol. Biol. Cell 23, 2645-2657 (2012).
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 2645-2657
-
-
Herskowitz, J.H.1
Offe, K.2
Deshpande, A.3
Kahn, R.A.4
Levey, A.I.5
Lah, J.J.6
-
10
-
-
0036827031
-
Intraneuronal Alzheimer aβ42 accumulates in multivesicular bodies and is associated with synaptic pathology
-
R. H. Takahashi, T. A. Milner, F. Li, E. E. Nam, M. A. Edgar, H. Yamaguchi, M. F. Beal, H. Xu, P. Greengard, G. K. Gouras, Intraneuronal Alzheimer aβ42 accumulates in multivesicular bodies and is associated with synaptic pathology. Am. J. Pathol. 161, 1869-1879 (2002).
-
(2002)
Am. J. Pathol.
, vol.161
, pp. 1869-1879
-
-
Takahashi, R.H.1
Milner, T.A.2
Li, F.3
Nam, E.E.4
Edgar, M.A.5
Yamaguchi, H.6
Beal, M.F.7
Xu, H.8
Greengard, P.9
Gouras, G.K.10
|