Impurity profiling of carbocisteine by HPLC-CAD, qNMR and UV/vis spectroscopy

Journal of Pharmaceutical and Biomedical Analysis

Volumn 95, Issue , 2014, Pages 1-10

  Wahl, Oliver ^a   Holzgrabe, Ulrike ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Amino acids; Carbocisteine; Corona charged aerosol detector; Impurity stability; Pharmaceutical analysis

Indexed keywords

ACETONITRILE; CARBOCISTEINE; CHLOROACETIC ACID; CYSTEINE; CYSTINE; MALEIC ACID; N,S DICARBOXYMETHYLCYSTEINE; TRIFLUOROACETIC ACID; UNCLASSIFIED DRUG;

AEROSOL; ANALYTIC METHOD; ARTICLE; CATION EXCHANGE; CONTROLLED STUDY; CORONA CHARGED AEROSOL DETECTION; DRUG IMPURITY; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHOBICITY; LIMIT OF DETECTION; MEASUREMENT PRECISION; MEASUREMENT REPEATABILITY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PARTICLE SIZE; PRACTICE GUIDELINE; PRIORITY JOURNAL; ULTRAVIOLET SPECTROSCOPY; VALIDATION STUDY; DRUG CONTAMINATION; DRUG STABILITY; PROCEDURES; ULTRAVIOLET SPECTROPHOTOMETRY;

CARBOCYSTEINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG CONTAMINATION; DRUG STABILITY; MAGNETIC RESONANCE SPECTROSCOPY; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 84896323106     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2014.02.012     Document Type: Article

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