-
1
-
-
85024125506
-
-
Global Initiative for Asthma (GINA). The global burden of asthma report. 2011 update
-
Global Initiative for Asthma (GINA). The global burden of asthma report. 2011 update.
-
-
-
-
2
-
-
78650034465
-
Air pollution and children’s respiratory symptoms in six cities of Northern China
-
Pan G, Zhang S, Feng Y et al. Air pollution and children’s respiratory symptoms in six cities of Northern China. Respir. Med. 2010; 104: 1903-11.
-
(2010)
Respir. Med
, vol.104
, pp. 1903-1911
-
-
Pan, G.1
Zhang, S.2
Feng, Y.3
-
4
-
-
0035000763
-
Ozone-induced lung inflammation and hyperreactivity are mediated via tumor necrosis factor-alpha receptors
-
Cho HY, Zhang LY, Kleeberger SR et al. Ozone-induced lung inflammation and hyperreactivity are mediated via tumor necrosis factor-alpha receptors. Am. J. Physiol. Lung Cell. Mol. Physiol. 2001; 280: L537-46.
-
(2001)
Am. J. Physiol. Lung Cell. Mol. Physiol
, vol.280
, pp. L537-L546
-
-
Cho, H.Y.1
Zhang, L.Y.2
Kleeberger, S.R.3
-
5
-
-
0036083588
-
IL-13 and IL-4 cause eotaxin release in human airway smooth muscle cells: A role for ERK
-
Moore PE, Church TL, Chism DD et al. IL-13 and IL-4 cause eotaxin release in human airway smooth muscle cells: a role for ERK. Am. J. Physiol. Lung Cell.Mol. Physiol. 2002; 282: L847-53.
-
(2002)
Am. J. Physiol. Lung Cell.Mol. Physiol
, vol.282
, pp. L847-L853
-
-
Moore, P.E.1
Church, T.L.2
Chism, D.D.3
-
6
-
-
0036231644
-
Effect of ozone exposure on allergic sensitization and airway inflammation induced by dendritic cells
-
Depuydt PO, Lambrecht BN, Joos GF et al. Effect of ozone exposure on allergic sensitization and airway inflammation induced by dendritic cells. Clin. Exp. Allergy 2002; 32: 391-6.
-
(2002)
Clin. Exp. Allergy
, vol.32
, pp. 391-396
-
-
Depuydt, P.O.1
Lambrecht, B.N.2
Joos, G.F.3
-
7
-
-
27744436303
-
Additive effect of diesel exhaust particulates and ozone on airway hyperresponsiveness and inflammation in a mouse model of asthma
-
Jang AS, Choi IS, Takizawa H et al. Additive effect of diesel exhaust particulates and ozone on airway hyperresponsiveness and inflammation in a mouse model of asthma. J. Korean Med. Sci. 2005; 20: 759-63.
-
(2005)
J. Korean Med. Sci
, vol.20
, pp. 759-763
-
-
Jang, A.S.1
Choi, I.S.2
Takizawa, H.3
-
8
-
-
33644507119
-
Prolonged ozone exposure in an allergic airway disease model: Adaptation of airway responsiveness and airway remodeling
-
Jang AS, Choi IS, Lee JH et al. Prolonged ozone exposure in an allergic airway disease model: adaptation of airway responsiveness and airway remodeling. Respir. Res. 2006; 7: 24.
-
(2006)
Respir. Res
, vol.7
, pp. 24
-
-
Jang, A.S.1
Choi, I.S.2
Lee, J.H.3
-
9
-
-
33746616816
-
Importance of p38 mitogenactivated protein kinase pathway in allergic airway remodelling and bronchial hyperresponsiveness
-
Nath P, Leung SY, Williams A et al. Importance of p38 mitogenactivated protein kinase pathway in allergic airway remodelling and bronchial hyperresponsiveness. Eur. J. Pharmacol. 2006; 544: 160-7.
-
(2006)
Eur. J. Pharmacol
, vol.544
, pp. 160-167
-
-
Nath, P.1
Leung, S.Y.2
Williams, A.3
-
10
-
-
55949102910
-
Role of p38 mitogenactivated protein kinase in ozone-induced airway hyperresponsiveness and inflammation
-
Williams AS, Issa R, Durham A et al. Role of p38 mitogenactivated protein kinase in ozone-induced airway hyperresponsiveness and inflammation. Eur. J. Pharmacol. 2008; 600: 117-22.
-
(2008)
Eur. J. Pharmacol
, vol.600
, pp. 117-122
-
-
Williams, A.S.1
Issa, R.2
Durham, A.3
-
11
-
-
79958710208
-
P38 mitogen-activated protein kinase pathways in asthma and COPD.
-
Chung KF. p38 mitogen-activated protein kinase pathways in asthma and COPD. Chest 2011; 139: 1470-9.
-
(2011)
Chest
, vol.139
, pp. 1470-1479
-
-
Chung, K.F.1
-
12
-
-
33746925579
-
Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1
-
Abraham SM, Lawrence T, Kleiman A et al. Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1. J. Exp.Med. 2006; 203: 1883-9.
-
(2006)
J. Exp.Med.
, vol.203
, pp. 1883-1889
-
-
Abraham, S.M.1
Lawrence, T.2
Kleiman, A.3
-
13
-
-
34248679869
-
Dual-specificity phosphatase 1: A critical regulator of innate immune responses
-
Abraham SM, Clark AR. Dual-specificity phosphatase 1: a critical regulator of innate immune responses. Biochem. Soc. Trans. 2006; 34: 1018-23.
-
(2006)
Biochem. Soc. Trans
, vol.34
, pp. 1018-1023
-
-
Abraham, S.M.1
Clark, A.R.2
-
14
-
-
0036841288
-
Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38
-
Lasa M, Abraham SM, Boucheron C et al. Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38. Mol. Cell. Biol. 2002; 22: 7802-11.
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 7802-7811
-
-
Lasa, M.1
Abraham, S.M.2
Boucheron, C.3
-
15
-
-
79953695109
-
Inhibition of p38 MAPKdependent bronchial contraction after ozone by corticosteroids
-
Li F, Zhang M, Hussain F et al. Inhibition of p38 MAPKdependent bronchial contraction after ozone by corticosteroids. Eur. Respir. J. 2011; 37: 933-42.
-
(2011)
Eur. Respir. J
, vol.37
, pp. 933-942
-
-
Li, F.1
Zhang, M.2
Hussain, F.3
-
16
-
-
77951196142
-
Effect of p38 MAPK inhibition on corticosteroid suppression of cytokine release in severe asthma
-
Bhavsar P, Khorasani N, Hew M et al. Effect of p38 MAPK inhibition on corticosteroid suppression of cytokine release in severe asthma. Eur. Respir. J. 2010; 35: 750-6.
-
(2010)
Eur. Respir. J
, vol.35
, pp. 750-756
-
-
Bhavsar, P.1
Khorasani, N.2
Hew, M.3
-
17
-
-
84869119470
-
Corticosteroid insensitivity of chemokine expression in airway smooth muscle of patients with severe asthma
-
Chang PJ, Bhavsar PK, Michaeloudes C et al. Corticosteroid insensitivity of chemokine expression in airway smooth muscle of patients with severe asthma. J. Allergy Clin. Immunol. 2012; 130: 877-85.
-
(2012)
J. Allergy Clin. Immunol
, vol.130
, pp. 877-885
-
-
Chang, P.J.1
Bhavsar, P.K.2
Michaeloudes, C.3
-
18
-
-
0037382808
-
Involvement of PTEN in airway hyperresponsiveness and inflammation in bronchial asthma
-
Kwak YG, Song CH, Yi HK et al. Involvement of PTEN in airway hyperresponsiveness and inflammation in bronchial asthma. J. Clin. Invest. 2003; 111: 1083-92.
-
(2003)
J. Clin. Invest
, vol.111
, pp. 1083-1092
-
-
Kwak, Y.G.1
Song, C.H.2
Yi, H.K.3
-
19
-
-
77956698524
-
Inflammatory changes in the airways of mice caused by cigarette smoke exposure are only partially reversed after smoking cessation
-
Braber S, Henricks PA, Nijkamp FP et al. Inflammatory changes in the airways of mice caused by cigarette smoke exposure are only partially reversed after smoking cessation. Respir.Res. 2010; 11: 99.
-
(2010)
Respir.Res.
, vol.11
, pp. 99
-
-
Braber, S.1
Henricks, P.A.2
Nijkamp, F.P.3
-
20
-
-
17144403761
-
Therapeutic administration of Budesonide ameliorates allergen-induced airway remodelling
-
McMillan SJ, Xanthou G, Lloyd CM et al. Therapeutic administration of Budesonide ameliorates allergen-induced airway remodelling. Clin. Exp. Allergy 2005; 35: 388-96.
-
(2005)
Clin. Exp. Allergy
, vol.35
, pp. 388-396
-
-
McMillan, S.J.1
Xanthou, G.2
Lloyd, C.M.3
-
21
-
-
0036846991
-
Dysfunction and remodeling of the mouse airway persist after resolution of acute allergen-induced airway inflammation
-
Leigh R, Ellis R, Wattie J et al. Dysfunction and remodeling of the mouse airway persist after resolution of acute allergen-induced airway inflammation. Am. J. Respir. Cell Mol. Biol. 2002; 27: 526-35.
-
(2002)
Am. J. Respir. Cell Mol. Biol
, vol.27
, pp. 526-535
-
-
Leigh, R.1
Ellis, R.2
Wattie, J.3
-
22
-
-
77956689713
-
Corticosteroid suppression of lipoxin A4 and leukotriene B4 from alveolar macrophages in severe asthma
-
Bhavsar PK, Levy BD, Hew MJ et al. Corticosteroid suppression of lipoxin A4 and leukotriene B4 from alveolar macrophages in severe asthma. Respir. Res. 2010; 11: 71.
-
(2010)
Respir. Res
, vol.11
, pp. 71
-
-
Bhavsar, P.K.1
Levy, B.D.2
Hew, M.J.3
-
23
-
-
84864239168
-
Restoration of corticosteroid sensitivity by p38 mitogen activated protein kinase inhibition in peripheral blood mononuclear cells from severe asthma
-
Mercado N, Hakim A, Kobayashi Y et al. Restoration of corticosteroid sensitivity by p38 mitogen activated protein kinase inhibition in peripheral blood mononuclear cells from severe asthma. PLoS ONE 2012; 7: e41582.
-
(2012)
Plos ONE
, vol.7
-
-
Mercado, N.1
Hakim, A.2
Kobayashi, Y.3
-
24
-
-
23644456321
-
ROS generated by pollen NADPH oxidase provide a signal that augments antigeninduced allergic airway inflammation
-
Boldogh I, Bacsi A, Choudhury BK et al. ROS generated by pollen NADPH oxidase provide a signal that augments antigeninduced allergic airway inflammation. J. Clin. Invest. 2005; 115: 2169-79.
-
(2005)
J. Clin. Invest
, vol.115
, pp. 2169-2179
-
-
Boldogh, I.1
Bacsi, A.2
Choudhury, B.K.3
-
25
-
-
33746520807
-
Pro-oxidative diesel exhaust particle chemicals inhibit LPS-induced dendritic cell responses involved in T-helper differentiation
-
Chan RC, Wang M, Li N et al. Pro-oxidative diesel exhaust particle chemicals inhibit LPS-induced dendritic cell responses involved in T-helper differentiation. J. Allergy Clin. Immunol. 2006; 118: 455-65.
-
(2006)
J. Allergy Clin. Immunol
, vol.118
, pp. 455-465
-
-
Chan, R.C.1
Wang, M.2
Li, N.3
-
26
-
-
38149091442
-
Targeting TNF-alpha: A novel therapeutic approach for asthma
-
quiz 1-2
-
Brightling C, Berry M, Amrani Y et al. Targeting TNF-alpha: a novel therapeutic approach for asthma. J.Allergy Clin. Immunol. 2008; 121: 5-10; quiz 1-2.
-
(2008)
J.Allergy Clin. Immunol
, vol.121
, pp. 5-10
-
-
Brightling, C.1
Berry, M.2
Amrani, Y.3
-
27
-
-
9644281044
-
Interleukin-13 in asthma pathogenesis
-
Wills-Karp M. Interleukin-13 in asthma pathogenesis. Immunol. Rev. 2004; 202: 175-90.
-
(2004)
Immunol. Rev
, vol.202
, pp. 175-190
-
-
Wills-Karp, M.1
-
28
-
-
34247500507
-
New molecular targets for the treatment of neutrophilic diseases
-
quiz 63-4
-
Barnes PJ. New molecular targets for the treatment of neutrophilic diseases. J. Allergy Clin. Immunol. 2007; 119: 1055-62; quiz 63-4.
-
(2007)
J. Allergy Clin. Immunol
, vol.119
, pp. 1055-1062
-
-
Barnes, P.J.1
-
29
-
-
79953718767
-
Cytokine/anti-cytokine therapy—novel treatments for asthma
-
Hansbro PM, Kaiko GE, Foster PS et al. Cytokine/anti-cytokine therapy—novel treatments for asthma? Br. J. Pharmacol. 2011; 163: 81-95.
-
(2011)
Br. J. Pharmacol
, vol.163
, pp. 81-95
-
-
Hansbro, P.M.1
Kaiko, G.E.2
Foster, P.S.3
-
30
-
-
0036057473
-
Biologic effects induced in vitro by PM10 from three different zones of Mexico City
-
Alfaro-Moreno E, Martinez L, Garcia-Cuellar C et al. Biologic effects induced in vitro by PM10 from three different zones of Mexico City. Environ. Health Perspect. 2002; 110: 715-20.
-
(2002)
Environ. Health Perspect
, vol.110
, pp. 715-720
-
-
Alfaro-Moreno, E.1
Martinez, L.2
Garcia-Cuellar, C.3
-
31
-
-
34250318956
-
Heat shock protein 27 functions in inflammatory gene expression and transforming growth factor-beta-activated kinase-1 (TAK1)-mediated signaling
-
Alford KA, Glennie S, Turrell BR et al. Heat shock protein 27 functions in inflammatory gene expression and transforming growth factor-beta-activated kinase-1 (TAK1)-mediated signaling. J. Biol. Chem. 2007; 282: 6232-41.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 6232-6241
-
-
Alford, K.A.1
Glennie, S.2
Turrell, B.R.3
-
32
-
-
33646473843
-
P38 MAP kinase inhibitors: A future therapy for inflammatory diseases
-
Mayer RJ, Callahan JF. P38 MAP kinase inhibitors: a future therapy for inflammatory diseases. Drug Discov. Today Ther. Strateg. 2006; 3: 49-54.
-
(2006)
Drug Discov. Today Ther. Strateg
, vol.3
, pp. 49-54
-
-
Mayer, R.J.1
Callahan, J.F.2
-
33
-
-
84862810230
-
MKP-1: A negative feedback effector that represses MAPK-mediated pro-inflammatory signaling pathways and cytokine secretion in human airway smooth muscle cells
-
Manetsch M, Che W, Seidel P et al. MKP-1: a negative feedback effector that represses MAPK-mediated pro-inflammatory signaling pathways and cytokine secretion in human airway smooth muscle cells. Cell. Signal. 2012; 24: 907-13.
-
(2012)
Cell. Signal
, vol.24
, pp. 907-913
-
-
Manetsch, M.1
Che, W.2
Seidel, P.3
-
34
-
-
81555210955
-
P38 mitogen-activated protein kinase-
-
Mercado N, To Y, Kobayashi Y et al. p38 mitogen-activated protein kinase-γ inhibition by long-acting β2 adrenergic agonists reversed steroid insensitivity in severe asthma. Mol. Pharmacol. 2011; 80: 1128-35.
-
(2011)
Mol. Pharmacol
, vol.80
, pp. 1128-1135
-
-
Mercado, N.1
To, Y.2
Kobayashi, Y.3
|