Computational modelling and analysis of mechanical conditions on cell locomotion and cell-cell interaction

Computer Methods in Biomechanics and Biomedical Engineering

Volumn 17, Issue 6, 2014, Pages 678-693

  Mousavi, S J ^a   Doweidar, M H ^a,b   Doblare M ^a,b  

^a UNIVERSITY OF ZARAGOZA   (Spain)

^b BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

Author keywords

3D finite element simulation; cell mechanosensing; cell migration; cell cell interaction; cell substrate interaction

Indexed keywords

CELLS; CYTOLOGY; INTERFACES (MATERIALS); MECHANICAL PROPERTIES; SUBSTRATES; THREE DIMENSIONAL;

3D FINITE-ELEMENT SIMULATION; CELL MIGRATION; CELL-CELL INTERACTION; CELL-SUBSTRATE INTERACTIONS; MECHANOSENSING;

BIOMECHANICS;

ARTICLE; CELL INTERACTION; CELL MIGRATION; CELL POPULATION; COMPUTER MODEL; EXTRACELLULAR MATRIX; FORCE; MODEL; PRIORITY JOURNAL; RIGIDITY; SIMULATION; VELOCITY;

BIOMECHANICAL PHENOMENA; CELL COMMUNICATION; CELL MOVEMENT; COMPUTER SIMULATION; MODELS, BIOLOGICAL;

EID: 84896299085     PISSN: 10255842     EISSN: 14768259     Source Type: Journal    
DOI: 10.1080/10255842.2012.710841     Document Type: Article

References (52)

1. AkiyamaSK, YamadaKM. 1985. The interaction of plasma fibronectin with fibroblastic cells in suspension. J Biol Chem. 260:4492-4500.
2. AndujarMB, MelinM, GuerretS, GrimaudJA. 1992. Cell migration influences collagen gel contraction. J Submicrosc Cytol Pathol. 24:145-154.
3. BehestiH, MarinoS. 2009. Cerebellar granule cells: insights into proliferation, differentiation, and role in medulloblastoma pathogenesis. J Appl Physiol. 41:435-445.
4. BershadskyAD, BalabanNQ, GeigerB. 2003. Adhesion-dependent cell mechanosensitivity. Annu Rev Cell Dev Biol. 19:677-695.
5. Borau C, Doweidar MH, Garcia-Aznar JM. 2010. Modeling of cell migration and mechano-sensing in 3d. 17th Congress of the European Society of Biomechanics. Edinburgh, UK.
6. BorauC, KammRD, García-AznarJM. 2011. Mechano-sensing and cell migration: a 3D model approach. J Phys Biol. 8:1078-1088.
7. BroflandGW, WiebeCJ. 2004. Mechanical effects of cell anisotropy on epithelia. Comput Methods Biomech Biomed Eng. 7:91-99.
8. BroflandGW, ViensD, VeldhuisJH. 2007. A new cell-based FE model for the mechanics of embryonic epithelia. Comput Methods Biomech Biomed Eng. 10:121-128.
9. BuxboimA, IvanovskaIL, DischerDE. 2010a. Matrix elasticity, cytoskeletal forces and physics of the nucleus: how deeply do cells 'feel' outside and in?J Cell Sci. 123:297-308.
10. BuxboimA, RajagopalK, BrownAEX, DischerDE. 2010b. How deeply cells feel: methods for thin gells. J Phys Condens Matter. 22(19):194116(10pp).
11. ChiquetM, GelmanL, LutzR, MaierS. 2009. Wound healing: aiming for perfect skin regeneration. Biochim Biophys Acta J. 1973:911-920.
12. DaltonBA, WalboomersXF, DziegielewskiM, EvansMDM, TaylorS, JansenJA, SteeleJG. 2001. Modulation of epithelial tissue and cell migration by microgrooves. Phil Trans Roy Soc London. 56:195-207.
13. DickinsonRB, TranquilloRT. 1993. Optimal estimation of cell movement indices from the statistical analysis of cell tracking data. Am Inst Chem Eng J. 39:1995-2010.
14. EastwoodM, PorterR, KhanU, McGroutherG, BrownR. 1996. Quantitative analysis of collagen gel contractile forces generated by dermal fibroblasts and the relationship to cell morphology. J Cell Physiol. 166:33-42.
15. EhrbarM, SalaA, LienemannP, RangaA, MosiewiczK, BittermannA, RizziSC, WeberFE. 2011. Elucidating the role of matrix stiffness in 3D cell migration and remodeling. Biophys J. 100:284-293.
16. EhrlichHP, RajaratnamJB. 1990. Cell locomotion forces versus cell contraction forces for collagen lattice contraction: an in vitro model of wound contraction. Tissue Cell. 22:407-417.
17. GranerF, GlazierJ. 1992. Simulations of biological cell sortin using a two-dimensional extended potts model. Phys Rev Lett. 69:2013-2016.
18. HadjipanayiE, MuderaV, BrownRA. 2009. Guiding cell migration in 3D: a collagen matrix with graded directional stiffness. Cell Motil Cytoskeleton. 66:435-445.
19. HarrisAK, WildP, StopakD. 1980. Silicone rubber substrata: a new wrinkle in the study of cell locomotion. Science. 208:177-179.
20. HibbitHD, KarlsonBI, SorensenP. 2006. ABAQUS Theory Manual, Version 6.10.Pawtucket, Rhode Island, USA.
21. IngberDE, TensegrityI. 2003. Cell structure and hierarchical systems biology. J Cell Sci. 116:1157-1173.
22. JamesDW, TaylorJF. 1969. The stress developed by sheets of chick fibroblasts in vitro. Exp Cell Res. 54:107-110.
23. JulianoRL, HaskillS. 1993. Signal transduction from the extracellular matrix. J Cell Biol. 120:577-585.
24. KanekarS, BorgTK, TerracioL, CarverW. 2000. Modulation of heart fibroblast migration and collagen gel contraction by IGF-I. Cell Adhes Commun. 7:513-523.
25. LauffenburgerDA, HorwitzAF. 1996. Cell migration: a physically integrated molecular process. Cell. 84:359-369.
26. LeeJ, IshiharaA, OxfordG, JohnsonB, JacobsonK. 1999. Regulation of cell movement is mediated by stretch-activated calcium channels. Nature. 400:382-386.
27. LoCM, WangHB, DemboM, WangYL. 2000. Cell movement is guided by the rigidity of the substrate. Biophys J. 79:144-152.
28. LeventalKR, YuH, KassL, LakinsJN, EgebladM, ErlerJT, FongSF, CsiszarK, GiacciaA, WeningerW, YamauchiM, GasserDL, WeaverVM.2009. Matrix cross linking forces tumor progression by enhancing integrin signaling. Cell. 139:891-906.
29. MartinP. 1997. Wound healing: aiming for perfect skin regeneration. Science. 276:75-81.
30. MoreoP, Garcia-AznarJM, DoblaréM. 2008. Modeling mechanosensing and its effect on the migration and proliferation of adherent cells. Acta Biomater. 4:613-621.
31. NossalR. 1988. On the elasticity of cytoskeletal networks. Biophys J. 53:349-359.
32. OdellGM, BonnerJT. 1986. How the dictyostelium discoideum grex crawls. Phil Trans Roy Soc London. 312:487-525.
33. OsterGF, MurrayJD, HarrisAK. 1983. Mechanical aspects of mesenchymal morphogenesis. J Embryol Exp Morph. 78:83-125.
34. PalssonE. 2001. A three-dimensional model of cell movement in multicellular systems. Future Gen Comput Syst. 17:835-852.
35. PelhamRJ, Jr, WangYL. 1997. Cell locomotion and focal adhesions are regulated by substrate flexibility. PNAS. 94:13661-13665.
36. PenelopeCG, JanmeyPA. 2005. Cell type-specific response to growth on soft materials. J Appl Physiol. 98:1547-1553.
37. PompeT, GloriusS, BischoffT, UhlmannI, KaufmannM, BrennerS, WernerC. 2009. Dissecting the impact of matrix anchorage and elasticity in cell adhesion. Biophys J. 97:2154-2163.
38. Ramis-CondeI, DrasdoD, AndersonARA, ChaplainM. 2008. Modeling the influence of the e-cadherin-b-catenin pathway in cancer cell invasion: a multiscale approach. Biophys J. 95:155-165.
39. RamtaniS. 2004. Mechanical modelling of cell/ECM and cell/cell interactions during the contraction of a fibroblast-populated collagen microsphere: theory and model simulation. J Biomech. 37:1709-1718.
40. RassierDE, MacIntoshBR, HerzogW. 1999. Length dependence of active force production in skeletal muscle. J Appl Physiol. 86:1445-1457.
41. RoyP, PetrollWM, CavanaghHD, JesterJV. 1999. Exertion of tractional force requires the coordinated up-regulation of cell contractility and adhesion. Cell Motil Cytoskeleton. 43:23-34.
42. SavillN, HogewegP. 1997. Modeling morphogenesis: from single cells to crawling slugs. J Theor Biol. 184:229-235.
43. SchäferA, RadmacherM. 2005. Influence of myosin ii activity on stiffness of fibroblast cells. Acta Biomater. 1:273-280.
44. SheetzMP, FelsenfeldD, GalbraithCG, ChoquetD. 1997. Cell migration as a five-step cycle. Biochem Soc Symp. 65:233-243.
45. ShiuYT, LiS, MarganskiW, UamiS, SchwartzMA, WangYL, DemboM, ChienS. 2004. Rho mediates the shear-enhancement of endothelial cell migration and traction force generation. Biophys J. 86:2558-2565.
46. ShreiberDI, BarocasVH, TranquilloRT. 2003. Temporal variations in cell migration and traction during fibroblast-mediated gel compaction. Biophys J. 84:4102-4114.
47. SpudichJA. 2001. The myosin swinging cross-bridge model. Nat Rev Mol Cell Biol. 2:387-392.
48. SureshS. 2007. Biomechanics and biophysics of cancer cells. Acta Biomater. 3:413-438.
49. TaylorDL, HeipleJ, WangYL, LunaEJ, TanasugarnL, BrierJ, SwansonJ, FechheimerM, AmatoP, RockwellM, DaleyG. 1982. Cellular and molecular aspects of amoeboid movement. CSH Symp Quant Biol. 46:101-111.
50. TimoshenkoS, GoodierJN. 1970. Theory of elasticity. New York: McGraw-Hill Publishing Co.
51. UlrichTA, PardoEMDJ, KumarS. 2009. The mechanical rigidity of the extracellular matrix regulates the structure, motility, and proliferation of glioma cells. Cancer Res. 69:4167-4174.
52. ZamanMH, KammRD, MatsudairaP, LauffenburgeryDA. 2005. Computational model for cell migration in three-dimensional matrices. Biophys J. 89:1389-1397.