-
1
-
-
67650938576
-
Hepatocellular carcinomaepidemiological trends and risk factors
-
Schütte K, Bornschein J, Malfertheiner P (2009) Hepatocellular carcinomaepidemiological trends and risk factors. Digest Dis 27(2): 80-92.
-
(2009)
Digest Dis
, vol.27
, Issue.2
, pp. 80-92
-
-
Schuḧtte, K.1
Bornschein, J.2
Malfertheiner, P.3
-
2
-
-
57749195128
-
Differential vascular endothelial growth factor A protein expression between small hepatocellular carcinoma and cirrhosis correlates with serum vascular endothelial growth factor A and a-fetoprotein
-
Corradini SG, Morini S, Liguori F, Carotti S, Onetti Muda A, et al. (2009) Differential vascular endothelial growth factor A protein expression between small hepatocellular carcinoma and cirrhosis correlates with serum vascular endothelial growth factor A and a-fetoprotein. Liver Int 29(1): 103-112.
-
(2009)
Liver Int
, vol.29
, Issue.1
, pp. 103-112
-
-
Corradini, S.G.1
Morini, S.2
Liguori, F.3
Carotti, S.4
Onetti Muda, A.5
-
3
-
-
77956627711
-
The role of signaling pathways in the development and treatment of hepatocellular carcinoma
-
Whittaker S, Marais R, Zhu AX (2010) The role of signaling pathways in the development and treatment of hepatocellular carcinoma. Oncogene 29(36): 4989-5005.
-
(2010)
Oncogene
, vol.29
, Issue.36
, pp. 4989-5005
-
-
Whittaker, S.1
Marais, R.2
Zhu, A.X.3
-
4
-
-
84863240722
-
Activation of PI3K/ AKT and MAPK pathway through a PDGFRb-dependent feedback loop is involved in rapamycin resistance in hepatocellular carcinoma
-
Li QL, Gu FM, Wang Z, Jiang JH, Yao LQ, et al. (2012) Activation of PI3K/ AKT and MAPK pathway through a PDGFRb-dependent feedback loop is involved in rapamycin resistance in hepatocellular carcinoma. PloS One 7(3): e33379.
-
(2012)
PloS One
, vol.7
, Issue.3
-
-
Li, Q.L.1
Gu, F.M.2
Wang, Z.3
Jiang, J.H.4
Yao, L.Q.5
-
5
-
-
19544392524
-
Ephrin-A1 expression contributes to the malignant characteristics of α-fetoprotein producing hepatocellular carcinoma
-
DOI 10.1136/gut.2004.049486
-
Iida H, Honda M, Kawai HF, Yamashita T, Shirota Y, et al. (2005) Ephrin-A1 expression contributes to the malignant characteristics of alpha-fetoprotein producing hepatocellular carcinoma. Gut 54(6): 843-851. (Pubitemid 40732104)
-
(2005)
Gut
, vol.54
, Issue.6
, pp. 843-851
-
-
Iida, H.1
Honda, M.2
Kawai, H.F.3
Yamashita, T.4
Shirota, Y.5
Wang, B.-C.6
Miao, H.7
Kaneko, S.8
-
6
-
-
65649086739
-
Alpha fetoproteinis a novelprotein-bindingpartner for caspase-3 and blocks the apoptoticsignalingpathway in humanhepatomacells
-
Li M, Li H, Li C, Zhou S, Guo L, et al. (2009) Alpha fetoproteinis a novelprotein-bindingpartner for caspase-3 and blocks the apoptoticsignalingpathway in humanhepatomacells. Int J Cancer 124(12): 2845-2854.
-
(2009)
Int J Cancer
, vol.124
, Issue.12
, pp. 2845-2854
-
-
Li, M.1
Li, H.2
Li, C.3
Zhou, S.4
Guo, L.5
-
7
-
-
0029083323
-
Downregulation of phorbol 12-myristate 13-acetateinduced tumor necrosis factor-alpha and interleukin-1 beta production and gene expression in human monocytic cells by human alpha-fetoprotein
-
Wang W, Alpert E (1995) Downregulation of phorbol 12-myristate 13-acetateinduced tumor necrosis factor-alpha and interleukin-1 beta production and gene expression in human monocytic cells by human alpha-fetoprotein. Hepatology 22: 921-928.
-
(1995)
Hepatology
, vol.22
, pp. 921-928
-
-
Wang, W.1
Alpert, E.2
-
8
-
-
0033791037
-
Human alpha-fetoprotein peptides bind estrogen receptor and estradiol, and suppress breast cancer
-
Vakharia D, Mizejewski GJ (2000) Human alpha-fetoprotein peptides bind estrogen receptor and estradiol, and suppress breast cancer. Breast Cancer Research Tr 63(1): 41-52.
-
(2000)
Breast Cancer Research Tr
, vol.63
, Issue.1
, pp. 41-52
-
-
Vakharia, D.1
Mizejewski, G.J.2
-
9
-
-
27644516300
-
Review of Growth Inhibitory Peptide as a Biotherapeutic agent for tumor growth, adhesion, and metastasis
-
DOI 10.1007/s10555-005-5135-2
-
Muehlemann M, Miller KD, Dauphinee M, Mizejewski GJ (2005) Review of Growth Inhibitory Peptide as a Biotherapeutic agent for tumor growth, adhesion, and metastasis. Cancer Metast Rev 24(3): 441-467. (Pubitemid 41569983)
-
(2005)
Cancer and Metastasis Reviews
, vol.24
, Issue.3
, pp. 441-467
-
-
Muehlemann, M.1
Miller, K.D.2
Dauphinee, M.3
Mizejewski, G.J.4
-
10
-
-
3242682760
-
Alpha-fetoprotein growth inhibitory peptides: Potential leads for cancer therapeutics
-
Mizejewski G, MacColl R (2003) Alpha-fetoprotein growth inhibitory peptides: potential leads for cancer therapeutics. Mol Cancer Ther 2: 1243-1255.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 1243-1255
-
-
Mizejewski, G.1
Maccoll, R.2
-
11
-
-
0036284086
-
The promoting molecular mechanism of alpha-fetoprotein on the growth of human hepatoma Bel7402 cell line
-
Li M, Li P (2002) The promoting molecular mechanism of alpha-fetoprotein on the growth of human hepatoma Bel7402 cell line. World J Gastroenterol 8(3): 469-475. (Pubitemid 34692744)
-
(2002)
World Journal of Gastroenterology
, vol.8
, Issue.3
, pp. 469-475
-
-
Li, M.-S.1
Li, P.-F.2
He, S.-P.3
Du, G.-G.4
Li, G.5
-
12
-
-
1842587679
-
Alpha-fetoprotein stimulated the expression of some oncogenes in human hepatocellular carcinoma Bel 7402 cells
-
Li M, Li P, He SP, Du GG, Li G, et al. (2004) Alpha-fetoprotein stimulated the expression of some oncogenes in human hepatocellular carcinoma Bel 7402 cells. World J Gastroenterol 10(6): 819-824. (Pubitemid 38418353)
-
(2004)
World Journal of Gastroenterology
, vol.10
, Issue.6
, pp. 819-824
-
-
Li, M.-S.1
Li, P.-F.2
Chen, Q.3
Du, G.-G.4
Li, G.5
-
13
-
-
26844522377
-
Effects of alpha fetoprotein on escape of Bel 7402 cells from attack of lymphocytes
-
Li M, Liu XH, Zhou S, Li PF, Li G (2005) Effects of alpha fetoprotein on escape of Bel 7402 cells from attack of lymphocytes. BMC cancer 5(1): 96-103.
-
(2005)
BMC Cancer
, vol.5
, Issue.1
, pp. 96-103
-
-
Li, M.1
Liu, X.H.2
Zhou, S.3
Li, P.F.4
Li, G.5
-
14
-
-
78649883907
-
Alpha-fetoprotein: A new member of intracellular signal molecules in regulation of the PI3K/AKT signaling in human hepatoma cell lines
-
Li M, Li H, Li C, Wang S, Jiang W, et alhttp://www.biomedcentral.com/ 1471-2407/5/96/-ins1. (2011) Alpha-fetoprotein: A new member of intracellular signal molecules in regulation of the PI3K/AKT signaling in human hepatoma cell lines. Int J Cancer 128(3): 524-532.
-
(2011)
Int J Cancer
, vol.128
, Issue.3
, pp. 524-532
-
-
Li, M.1
Li, H.2
Li, C.3
Wang, S.4
Jiang, W.5
-
15
-
-
1042279522
-
Vascular Endothelial Growth Factor Activates PI3K/Akt/Forkhead Signaling in Endothelial Cells
-
DOI 10.1161/01.ATV.0000110502.10593.06
-
Abid MR, Guo S, Minami T, Spokes KC, Ueki K, et al. (2004) Vascular endothelial growth factor activates PI3K/Akt/forkhead signaling in endothelial cells. Arterioscler Thromb Vasc Biol 24: 294-300. (Pubitemid 38197581)
-
(2004)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.24
, Issue.2
, pp. 294-300
-
-
Abid, Md.R.1
Guo, S.2
Minami, T.3
Spokes, K.C.4
Ueki, K.5
Skurk, C.6
Walsh, K.7
Aird, W.C.8
-
16
-
-
84859043508
-
Extract of Pleurotus pulmonarius suppresses liver cancer development and progression through inhibition of VEGF-induced PI3K/AKT signaling pathway
-
Xu W, Huang JJ, Cheung PCK (2012) Extract of Pleurotus pulmonarius suppresses liver cancer development and progression through inhibition of VEGF-induced PI3K/AKT signaling pathway. PLoS One 7(3): e34406.
-
(2012)
PLoS One
, vol.7
, Issue.3
-
-
Xu, W.1
Huang, J.J.2
Cheung, P.C.K.3
-
17
-
-
4944234987
-
Prognostic significance of serum vascular endothelial growth factor and endostatin in patients with hepatocellular carcinoma
-
DOI 10.1002/bjs.4594
-
Poon RT, Ho JW, Tong CS, Lau C, Ng IO, et al. (2004) Prognostic significance of serum vascular endothelial growth factor and endostatin in patients with hepatocellular carcinoma. Br J Surg 91(10): 1354-1360. (Pubitemid 39331462)
-
(2004)
British Journal of Surgery
, vol.91
, Issue.10
, pp. 1354-1360
-
-
Poon, R.T.P.1
Ho, J.W.Y.2
Tong, C.S.W.3
Lau, C.4
Ng, I.O.L.5
Fan, S.-T.6
-
18
-
-
0031778206
-
Clinical significance of microvessel density and vascular endothelial growth factor expression in hepatocellular carcinoma and surrounding liver: Possible involvement of vascular endothelial growth factor in the angiogenesis of cirrhotic liver
-
DOI 10.1002/hep.510270613
-
Elassal ON, Yamanoi A, Soda Y, Yamaguchi M, Igarashi M, et al. (1998) Clinical significance of microvessel density and vascular endothelial growth factor expression in hepatocellular carcinoma and surrounding liver: possible involvement of vascular endothelial growth factor in the angiogenesis of cirrhoticliver. Hepatology 27: 1554-1562. (Pubitemid 28264678)
-
(1998)
Hepatology
, vol.27
, Issue.6
, pp. 1554-1562
-
-
El-Assal, O.N.1
Yamanoi, A.2
Soda, Y.3
Yamaguchi, M.4
Igarashi, M.5
Yamamoto, A.6
Nabika, T.7
Nagasue, N.8
-
19
-
-
0031807538
-
Expression of vascular endothelial growth factor in human hepatocellular carcinoma
-
Yamaguchi R, Yano H, Iemura A, Ogasawara S, Haramaki M, et al. (2003) Expression of vascular endothelial growth factor in human hepatocellular carcinoma. Hepatology 28(1): 68-77.
-
(2003)
Hepatology
, vol.28
, Issue.1
, pp. 68-77
-
-
Yamaguchi, R.1
Yano, H.2
Iemura, A.3
Ogasawara, S.4
Haramaki, M.5
-
20
-
-
33344467123
-
VEGF function in vascular pathogenesis
-
DOI 10.1016/j.yexcr.2005.11.008, PII S001448270500532X
-
Ng YS, Krilleke D, Shima DT (2006) VEGF function in vascular pathogenesis. Exp Cell Res 312(5): 527-537. (Pubitemid 43290330)
-
(2006)
Experimental Cell Research
, vol.312
, Issue.5
, pp. 527-537
-
-
Ng, Y.-S.1
Krilleke, D.2
Shima, D.T.3
-
21
-
-
57749189578
-
Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: A phase III randomised, double-blind, placebo-controlled trial
-
Cheng AL, Kang YK, Chen Z, Tsao CJ, Qin S, et al. (2009) Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet Oncol 10(1): 25-34.
-
(2009)
Lancet Oncol
, vol.10
, Issue.1
, pp. 25-34
-
-
Cheng, A.L.1
Kang, Y.K.2
Chen, Z.3
Tsao, C.J.4
Qin, S.5
-
22
-
-
47949116252
-
Sorafenib in advanced hepatocellular carcinoma
-
Josep ML, Sergio R, Vincenzo M, Philip H, Edward G, et al. (2008) Sorafenib in advanced hepatocellular carcinoma. New Engl J Med 359(4): 378-390.
-
(2008)
New Engl J Med
, vol.359
, Issue.4
, pp. 378-390
-
-
Josep, M.L.1
Sergio, R.2
Vincenzo, M.3
Philip, H.4
Edward, G.5
-
23
-
-
33644747449
-
BAY 43-9006 inhibition of oncogenic RET mutants
-
Francesca C, Suresh A, Teresa G, Giuliana S, Giancarlo T, et al. (2006) BAY 43-9006 inhibition of oncogenic RET mutants. J Natl Cancer Inst 98(5): 326-334.
-
(2006)
J Natl Cancer Inst
, vol.98
, Issue.5
, pp. 326-334
-
-
Francesca, C.1
Suresh, A.2
Teresa, G.3
Giuliana, S.4
Giancarlo, T.5
-
24
-
-
4944249117
-
BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis
-
DOI 10.1158/0008-5472.CAN-04-1443
-
Wilhelm SM, Carter C, Tang L, Wilkie D, McNabola A, et al. (2004) BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/ MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. Cancer Res 64(19): 7099-7109. (Pubitemid 39331023)
-
(2004)
Cancer Research
, vol.64
, Issue.19
, pp. 7099-7109
-
-
Wilhelm, S.M.1
Carter, C.2
Tang, L.3
Wilkie, D.4
McNabola, A.5
Rong, H.6
Chen, C.7
Zhang, X.8
Vincent, P.9
McHugh, M.10
Cao, Y.11
Shujath, J.12
Gawlak, S.13
Eveleigh, D.14
Rowley, B.15
Liu, L.16
Adnane, L.17
Lynch, M.18
Auclair, D.19
Taylor, I.20
Gedrich, R.21
Voznesensky, A.22
Riedl, B.23
Post, L.E.24
Bollag, G.25
Trail, P.A.26
more..
-
25
-
-
67649946279
-
Efficacy, safety, and potentialbiomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: A phase II study
-
Zhu AX, Sahani DV, Duda DG, Tomaso E, Ancukiewicz M, et al. (2009) Efficacy, safety, and potentialbiomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: a phase II study. J Clin Oncol 27(18): 3027-3035.
-
(2009)
J Clin Oncol
, vol.27
, Issue.18
, pp. 3027-3035
-
-
Zhu, A.X.1
Sahani, D.V.2
Duda, D.G.3
Tomaso, E.4
Ancukiewicz, M.5
-
26
-
-
1542336952
-
Rational siRNA design for RNA interference
-
DOI 10.1038/nbt936
-
Reynolds A, Leake D, Boese Q, Scaringe S, Marshall WS, et al. (2004) Rational siRNA design for RNA interference. Nat biotechnol 22(3): 326-330. (Pubitemid 38295766)
-
(2004)
Nature Biotechnology
, vol.22
, Issue.3
, pp. 326-330
-
-
Reynolds, A.1
Leake, D.2
Boese, Q.3
Scaringe, S.4
Marshall, W.S.5
Khvorova, A.6
-
27
-
-
0141988568
-
Fundamental concepts of the angiogenic process
-
DOI 10.2174/1566524033479465
-
Folkman J (2003) Fundamental concepts of the angiogenic process. Curr Med Chem 3(7): 643-651. (Pubitemid 37236406)
-
(2003)
Current Molecular Medicine
, vol.3
, Issue.7
, pp. 643-651
-
-
Folkman, J.1
-
28
-
-
7244250405
-
Angiogenesis and hepatocellular carcinoma
-
DOI 10.1016/j.jhep.2004.09.006, PII S0168827804003940
-
Semela D, Dufour JF (2004) Angiogenesis and hepatocellular carcinoma. J Hepatol 41(5): 864-880. (Pubitemid 39434320)
-
(2004)
Journal of Hepatology
, vol.41
, Issue.5
, pp. 864-880
-
-
Semela, D.1
Dufour, J.-F.2
-
29
-
-
33746036817
-
Clinical value of apoptosis and angiogenesis factors in estimating the prognosis of hepatocellular carcinoma
-
DOI 10.1007/s00432-006-0097-5
-
Guo RP, Zhong C, Shi M, Zhang CQ, Wei W, et al. (2006) Clinical value of apoptosis and angiogenesis factors in estimating the prognosis of hepatocellular carcinoma. J Cancer Res Clin Oncol 132: 547-555. (Pubitemid 44078523)
-
(2006)
Journal of Cancer Research and Clinical Oncology
, vol.132
, Issue.9
, pp. 547-555
-
-
Guo, R.-P.1
Zhong, C.2
Shi, M.3
Zhang, C.-Q.4
Wei, W.5
Zhang, Y.-Q.6
Li, J.-Q.7
-
30
-
-
16544387834
-
Angiogenesis of AFP producing gastric carcinoma: Correlation with frequent liver metastasis and its inhibition by anti-AFP antibody
-
Yutaka T, Takahito O, Masayoshi M (2004) Angiogenesis of AFP producing gastric carcinoma: correlation with frequent liver metastasis and its inhibition by anti-AFP antibody. Oncol Rep 11(4): 809-813.
-
(2004)
Oncol Rep
, vol.11
, Issue.4
, pp. 809-813
-
-
Yutaka, T.1
Takahito, O.2
Masayoshi, M.3
-
31
-
-
1642325178
-
Oncodevelopmental a-fetoprotein acts as a selective proangiogenic factor on endothelial cell from the fetomaternal unit
-
Olin DL, Thomas K, Jessica E, Jasmin R, Nelli B, et al. (2004) Oncodevelopmental a-fetoprotein acts as a selective proangiogenic factor on endothelial cell from the fetomaternal unit. J Clin Endocr Metab 89(3): 1415-1422.
-
(2004)
J Clin Endocr Metab
, vol.89
, Issue.3
, pp. 1415-1422
-
-
Olin, D.L.1
Thomas, K.2
Jessica, E.3
Jasmin, R.4
Nelli, B.5
-
32
-
-
0036512208
-
New functions for the matrix metalloproteinases in cancer progression
-
Egeblad M, Werb Z (2002) New functions for the matrix metalloproteinases in cancer progression. Nat Rev Cancer 2(3): 161-174. (Pubitemid 37328786)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.3
, pp. 161-174
-
-
Egeblad, M.1
Werb, Z.2
|