The impact of including spatially longitudinal heterogeneities of vessel oxygen content and vascular fraction in 3D tumor oxygenation models on predicted radiation sensitivity

Medical Physics

Volumn 41, Issue 4, 2014, Pages

  Lagerlöf, Jakob H ^a   Kindblom, Jon ^b   Bernhardt, Peter ^a,b  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

dosimetry; hypoxia; modeling; radiotherapy; tumor control probability

Indexed keywords

BLOOD; BLOOD VESSELS; CELL DEATH; DOSIMETRY; MODELS; OXYGEN; OXYGENATION; RADIOTHERAPY; TABLE LOOKUP; TISSUE ENGINEERING;

GREEN'S FUNCTION APPROACHES; HYPOXIA; LONGITUDINAL VARIATIONS; MICHAELIS-MENTEN EQUATIONS; OXYGEN DISTRIBUTION; RADIATION SENSITIVITY; TUMOR CONTROL PROBABILITY; VASCULAR FRACTIONS;

TUMORS;

ARTICLE; BLOOD FLOW; BLOOD FLOW VELOCITY; BLOOD OXYGEN TENSION; BLOOD OXYGENATION; BLOOD VESSEL; BLOOD VESSEL PARAMETERS; CANCER CONTROL; CANCER RADIOTHERAPY; CELL SURVIVAL; CONSTANT VESSEL OXYGEN PRESSURE; DIFFUSION COEFFICIENT; DOSIMETRY; HUMAN; HYPOXIA; LINEAR ENERGY TRANSFER; MICHAELIS MENTEN KINETICS; OXYGEN CONSUMPTION; OXYGEN DIFFUSION; OXYGEN ENHANCEMENT RATIO; OXYGEN SATURATION; OXYGEN TENSION; OXYGENATION; PRESSURE GRADIENT; RADIATION DOSE; RADIATION EXPOSURE; RADIATION RESPONSE; RADIOSENSITIVITY; TUMOR CELL; TUMOR GROWTH; TUMOR MODEL; TUMOR NECROSIS; TUMOR VASCULARIZATION; TUMOR VOLUME; VASCULAR FRACTION; BIOLOGICAL MODEL; BLOOD; CIRCULATION; METABOLISM; NECROSIS; NEOPLASMS; PATHOLOGY; VASCULARIZATION;

OXYGEN;

BLOOD CIRCULATION; BLOOD VESSELS; MODELS, BIOLOGICAL; NECROSIS; NEOPLASMS; OXYGEN; RADIATION TOLERANCE; TUMOR BURDEN;

EID: 84896274662     PISSN: 00942405     EISSN: None     Source Type: Journal    
DOI: 10.1118/1.4866887     Document Type: Article

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