In vivo measurement of T2 distributions and water contents in normal human brain

Magnetic Resonance in Medicine

Volumn 37, Issue 1, 1997, Pages 34-43

  Whittall, Kenneth P ^a,b   MacKay, Alex L ^a   Graeb, Douglas A ^a   Nugent, Robert A ^a   Li, David K B ^a   Paty, Donald W ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b VANCOUVER HOSPITAL AND HEALTH SCIENCES CENTRE   (Canada)

Author keywords

brain white and gray matter; myelin content; T2 relaxation; water content

Indexed keywords

MAGNETIC RESONANCE IMAGING; WATER CONTENT;

BRAIN STRUCTURE; GRAY MATTER; IN-VIVO MEASUREMENT; INTERNAL CAPSULES; MYELIN CONTENT; QUANTITATIVE MEASUREMENT; T2 RELAXATION; WATER ENVIRONMENTS;

BRAIN;

ADULT; ARTICLE; BRAIN TISSUE; BRAIN WATER; FEMALE; GRAY MATTER; HUMAN; HUMAN EXPERIMENT; MALE; MYELINATION; NEURORADIOLOGY; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; TISSUE DISTRIBUTION; WHITE MATTER; ALGORITHM; BODY WATER; BRAIN; HISTOLOGY; IMAGE QUALITY; METABOLISM; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

DIAGNOSTIC AGENT; MYELIN PROTEIN;

ADULT; ALGORITHMS; BODY WATER; BRAIN; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MYELIN PROTEINS; PHANTOMS, IMAGING;

EID: 0030614782     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrm.1910370107     Document Type: Article

References (57)

1. 2 quantitation for clinical applications. J. Magn. Reson. Imaging 2, 541-553 (1992).
2. R. K. Breger, F. W. Wehrli, H. C. Charles, J. R. MacFall, V. M. Haughton, Reproducibility of relaxation and spin-density parameters in phantoms and the human brain measured by MR imaging at 1.5 T. Magn. Reson. Med. 3, 649-662 (1986).
3. 2 measurements on a 1.5-T commercial MR imager. Radiology 171, 273-276 (1989).
4. 1 measured in the brain of patients with multiple sclerosis. Magn. Reson. Imaging 10, 579-584 (1992).
5. J. Vymazal, R. A. Brooks, C. Baumgarner, V. Tran, D. Katz, J. W. M. Bulte, E. R. Nauminger, G. D. Chiro, The relation between brain iron and NMR relaxation times. Magn. Reson. Med. 35, 56-61 (1996).
6. F. Q. Ye, W. R. W. Martin, P. S. Allen, Estimation of the iron concentration in excised gray matter by means of proton relaxation measurements. Magn. Reson. Med. 35, 285-289 (1996).
7. 2 estimation using multislice multiple-echo imaging. Magn. Reson. Med. 4, 34-47 (1987).
8. D. W. Marquardt, An algorithm for least squares estimation of non-linear parameters. J. Soc. Ind. Appl. Math. 11, 431-441 (1963).
9. J. P. Armspach, D. Gounot, I. J. Namer, H. H. Ohlenbusch, L. Rumbach, J. Chambron, Quantitative cerebral magnetic resonance imaging during ACTH treatment of multiple sclerosis. Magn. Reson. Imaging 11, 1147-1153 (1993).
10. R. V. Mulkern, S. T. S. Wong, P. Jakab, A. R. Bleier, T. Sandor, F. A. Jolesz, CPMG imaging sequences for high field in vivo transverse relaxation studies. Magn. Reson. Med. 16, 67-79 (1990).
11. 2 relaxation analysis. Magn. Reson. Imaging 12, 1099-1109 (1994).
12. R. M. Kroeker, R. M. Henkelman, Analysis of biological NMR relaxation data with continuous distributions of relaxation times. J. Magn. Reson. 69, 218-235 (1986).
13. K. P. Whittall, A. L. MacKay, Quantitative interpretation of NMR relaxation data. J. Magn. Reson. 84, 134-152 (1989).
14. K. P. Whittall, M. J. Bronskill, R. M. Henkelman, Investigation of analysis techniques for complicated NMR relaxation data. J. Magn. Reson. 95, 221-234 (1991).
15. R. S. Menon, P. S. Allen, Application of continuous relaxation time distributions to the fitting of data from model systems and excised tissue. Magn. Reson. Med. 20, 214-227 (1981).
16. C. L. Lawson, R. J. Hanson, "Solving Least Squares Problems," Prentice-Hall. Englewood Gliffs, 1974.
17. W. A. Stewart, A. L. MacKay, K. P. Whittall, G. R. W. Moore, D. W. Paty, Spin-spin relaxation in experimental allergic encephalomyelitis: analysis of CPMG data using a non-linear least-squares method and linear inverse theory. Magn. Reson. Med. 29, 767-775 (1993).
18. A. L. MacKay, K. P. Whittall, J. Adler, D. K. B. Li, D. W. Paty, D. A. Graeb, In vivo visualization of myelin water in brain by magnetic resonance. Magn. Reson. Med. 31, 673-677 (1994).
19. D. G. Gardner, J. C. Gardner, G. Laush, W. W. Meinke, Method for the analysis of multicomponent exponential decay curves. J. Chem. Phys. 31, 978-986 (1959).
20. S. W. Provencher, A Fourier method for the analysis of exponential decay curves. Biophys. J. 16, 27-41 (1976).
21. J. G. McWhirter, E. R. Pike, On the numerical inversion of the Laplace transform and similar Fredholm integral equations of the first kind. J. Phys. A Math. Gen. 11, 1729-1745 (1978).
22. S. W. Provencher, A constrained regularization method for inverting data represented by linear algebraic or integral equations. Compat. Phys. Commun. 27, 213-227 (1982).
23. H. Barkhuijsen, R. de Beer, W. M. M. J. Boveé, D. van Ormondt, Retrieval of frequencies, amplitudes, damping factors, and phases from time-domain signals using a linear least-squares procedure. J. Magn. Reson. 61, 465-481 (1985).
24. E. Yeramian, P. Claverie, Analysis of multiexponential functions without a hypothesis as to the number of components. Nature 326, 169-174 (1987).
25. P. S. Tofts, Standing waves in uniform water phantoms. J. Magn. Reson. B 104, 143-147 (1994).
26. W. A. Edelstein, P. A. Bottomley, L. M. Pfeifer, A signal-to-noise calibration procedure for NMR imaging systems. Medical Phys. 11, 180-185 (1984).
27. R. L. Void, R. R. Void, H. E. Simon, Errors in measurements of transverse relaxation rates. J. Magn. Reson. 11, 283-298 (1973).
28. 2 relaxation data. Magn. Reson. Med. 35, 370-378 (1998).
29. 2 in the cerebrum: correlation with age, gender, and demographic factors. Radiology 181, 545-547 (1991).
30. J. R. MacFall, F. W. Wehrli, R. K. Breger, G. A. Johnson, Methodology for the measurement and analysis of relaxation times in proton imaging. Magn. Reson. Imaging 5, 209-220 (1987).
31. H. M. Pappius, W. Feindel (Eds.), "Dynamics of Brain Edema," Springer-Verlag, Berlin, 1976.
32. T. Ernst, R. Kreis, B. D. Ross, Absolute quantitation of water and metabolites in the human brain: I. Compartments and water. J. Magn. Reson. B 102, 1-8 (1993).
33. P. Christiansen, P. B. Toft, P. Gideon, E. R. Danielsen, P. Ring, O. Henriksen, MR-visible water content in human brain: a proton MRS study. Magn. Reson. Imaging 12, 1237-1244 (1994).
34. V. Rajanayagam, M. E. Fabry, J. G. Gore, In vivo quantitation of water content in muscle tissues by NMR imaging, Magn. Reson. Imaging 9, 621-625 (1991).
35. J. R. Mayo, A. L. MacKay, K. P. Whittall, E. M. Baile, P. D. Paré, Measurement of lung water content and pleural pressure gradient with magnetic resonance imaging. J. Thorac. Imaging 10, 73-81 (1995).
36. M. Bloom, K. T. Holmes, G. E. Mountford, P. G. Williams, Complete proton magnetic resonance in whole cells. J. Magn. Reson. 69, 73-91 (1986).
37. H. W. Fischer, P. A. Rinck, Y. V. Haverbeke, R. N. Muller, Nuclear relaxation of human brain gray and white matter: analysis of field dependence and implications for MRI. Magn. Reson. Med. 16, 317-334 (1990).
38. H. Takagi, K. Shapiro, A. Marmarou, H. Wisoff, Microgravimetric analysis of human brain tissue: correlation with computerized tomography scanning. J. Neurosurg. 54, 797-801 (1981).
39. R. M. Torack, H. Alcala, M. Gado, R. Burton, Correlative assay of computerized cranial tomography (CCT), water content and specific gravity in normal and pathological postmortem brain. J. Neuropath. Exp. Neurol. 35, 385-392 (1976).
40. R. A. Brooks, G. Di Chiro, M. R. Keller, Explanation of cerebral white-gray contrast in computed tomography. J. Comput. Assist. Tomogr. 4, 489-491 (1980).
41. 1 measurements: effect of total water content, hydration fraction, and field strength. Magn. Reson. Med. 17, 402-413 (1991).
42. Y. Kaneoke, M. Furuse, S, Inao, K. Saso, K. Yoshida, Y. Motegi, M. Mizuno, A. Izawa, Spin-lattice relaxation times of bound water - its determination and implications for tissue discrimination. Magn. Reson. Imaging 5, 415-420 (1987).
43. R. M. Henkelman, G. J. Stanisz, J. K. Kim, M. J. Bronskill, Anisotropy of NMR properties of tissues. Magn. Reson. Med. 32, 592-601 (1994).
44. 2 relaxation components. Magn. Reson. Med. 33, 490-496 (1995).
45. 2 relaxation measurements of brain may provide myelin concentration, in "Proc., SMRM, 10th Annual Meeting, San Francisco, 1991," p. 917.
46. B. K. Rutt, J. D. Mitchell, Myelin-selective imaging with 3D fast spin echo MRI, in "Proc., SMRM, 12th Annual Meeting, New York, 1993," p. 137.
47. V. Vasilescu, E. Katona, V. Simplaceanu, D. Demco, Water compartments in myelinated nerve III Pulsed NMR results. Experientia 34, 1443-1444 (1978).
48. 2 relaxation of peripheral nerve measured in vivo. Magn. Reson. Imaging 13, 575-580 (1995).
49. 2 in the brain of patients with acute attack of multiple sclerosis. Magn. Reson. Med. 11, 337-348 (1989).
50. 2 relaxation in the brain of patients with multiple sclerosis. Magn. Reson. Imaging 9, 107-113 (1991).
51. 2-weighted MRI of normal gray matter and iron concentration. J. Magn. Reson. Imaging 5, 554-560 (1995).
52. 2 and assays of iron and ferritin in Parkinson and Huntington disease. Am. J. Neuroradiol. 14, 275-281 (1993).
53. T. L. Chenevert, J. A. Brunberg, J. G. Pipe, Anisotropic diffusion in human white matter: demonstration with MR techniques in vivo. Radiology 177, 401-405 (1990).
54. W. T. Norton, W. Gammer, in "Myelin" (P. Morell, Ed.), p. 147, Plenum Press, New York, 1984.
55. C. D. Araujo, A. L. MacKay, K. P. Whittall, J. R. T. Hailoy, A diffusion model for spin-spin relaxation of compartmentalized water in wood. J. Magn. Reson. B 101, 248-261 (1993).
56. K. R. Brownstein, C. E. Tarr, Importance of classical diffusion in NMR studies of water in biological cells. Phys. Rev. A 19, 2446-2453 (1979).
57. K. P. Whittall, Recovering compartment sizes from NMR relaxation data. J. Magn. Reson. 94, 486-492 (1991).