The current evidence in support of multimodal treatment of locally advanced, potentially resectable esophageal cancer

Digestive Diseases

Volumn 32, Issue 1-2, 2014, Pages 171-175

  Zacherl, Johannes ^a  

^a Center for Esophageal and Gastric Surgery Division of General Surgery   (Austria)

Author keywords

Esophageal cancer; Esophagectomy; Multimodal therapy; Neoadjuvant treatment; Outcome

Indexed keywords

CISPLATIN; FLUOROURACIL;

ADJUVANT CHEMORADIOTHERAPY; ADJUVANT CHEMOTHERAPY; ADVANCED CANCER; CANCER CHEMOTHERAPY; CANCER LOCALIZATION; CANCER SURGERY; ESOPHAGUS CANCER; ESOPHAGUS RESECTION; HUMAN; META ANALYSIS (TOPIC); MULTIMODALITY CANCER THERAPY; OVERALL SURVIVAL; PATIENT SELECTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; ARTICLE; CANCER ADJUVANT THERAPY; CANCER MORTALITY; CHEMORADIOTHERAPY; DECISION TREE; ENDOSCOPIC ECHOGRAPHY; ESOPHAGEAL ADENOCARCINOMA; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; MORBIDITY; MULTIDETECTOR COMPUTED TOMOGRAPHY; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; SURVIVAL RATE;

CHEMORADIOTHERAPY; COMBINED MODALITY THERAPY; ESOPHAGEAL NEOPLASMS; HUMANS; NEOPLASM STAGING; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TUMOR MARKERS, BIOLOGICAL;

EID: 84896137395     PISSN: 02572753     EISSN: 14219875     Source Type: Journal    
DOI: 10.1159/000357189     Document Type: Review

References (15)

1. Moehler M, Al-Batran SE, Andus T, et al: German S3-guideline 'Diagnosis and treatment of esophagogastric cancer' (in German). Z Gastroenterol 2011; 49: 461-531.
2. Kelsen DP, Winter KA, Gunderson LL, et al: Long term results of RTOG trial 8911 (USA Intergroup 113): a random assignment trial comparison of chemotherapy followed by surgery compared with surgery alone for esophageal cancer. J Clin Oncol 2007; 24: 3719-3725. (Pubitemid 47372613)
3. Vallböhmer D, Hölscher AH, Dietlein M, Bollschweiler E, Baldus SE, Mönig SP, Metzger R, Schicha H, Schmidt M: [18F]-Fluorodeoxyglucose- positron emission tomography for the assessment of histopathologic response and prognosis after completion of neoadjuvant chemoradiation in esophageal cancer. Ann Surg 2009; 250: 888-894.
4. Cunningham D, Allum WH, Stenning SP, et al: Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer. N Engl J Med 2006; 335: 11-20.
5. Schuhmacher C, Gretschel S, Lordick F, et al: Neoadjuvant chemotherapy compared with surgery alone for locally advanced cancer of the stomach and cardia: European Organisation for Research and Treatment of Cancer randomized trial 40954. J Clin Oncol 2010; 28: 5210-5218.
6. Ychou M, Boige V, Pignon JP, et al: Perioperative chemotherapy compared with surgery alone for resectable gastroesophageal adenocarcinoma: FNCLCC and FFCD multicenter phase III trial. J Clin Oncol 2011; 29: 1715-1721.
7. Allum WH, Stenning SP, Bancewicz J, et al: Long-term results of a randomized trial of surgery with or without preoperative chemotherapy in esophageal cancer. J Clin Oncol 2009; 27: 5062-5067.
8. van Hagen P, Hushof MC, van Lanschot JJ, et al: Preoperative chemoradiotherapy for esophageal or junctional cancer. N Engl J Med 2012,366: 2074-2084.
9. Stahl M, Walz MK, Stuschke M, et al: Phase III comparison of preoperative chemotherapy compared with chemoradiotherapy in patients with locally advanced adenocarcinoma of the esophagogastric junction. J Clin Oncol 2009; 27: 851-856.
10. Urba SG, Orringer MB, Turrisi A, Iannettoni M, Forastiere A, Strawderman M: Randomized trial of preoperative chemoradiation versus surgery alone in patients with locoregional esophageal carcinoma. J Clin Oncol 2001; 19: 305-313. (Pubitemid 32112841)
11. Walsh TN, Noonan N, Hollywood D, Kelly A, Keeling N, Hennessy TP: A comparison of multimodal therapy and surgery for esophageal adenocarcinoma. N Engl J Med 1996; 335: 462-467. (Pubitemid 26269945)
12. Lv J, Cao XF, Zhu B, Ji L, Tao L, Wang DD: Effect of neoadjuvant chemoradiotherapy on prognosis and surgery for esophageal carcinoma. World J Gastroenterol 2009; 15: 4962-4968.
13. Bedenne L, Michel P, Bouche O, et al: Chemoradioation followed by surgery compared with chemoradiation alone in squamous cancer of the esophagus: FFCD 9102. J Clin Oncol 2007; 25: 1160-1168. (Pubitemid 46640561)
14. Stahl M, Stuschke M, Lehmann N, et al: Chemoradioation with and without surgery in patients with locally advanced squamous cell carcinoma of the esophagus. J Clin Oncol 2005; 23: 2310-2317. (Pubitemid 46218723)
15. Ronellenfitsch U, Schwarzbach M, Hofheinz R, Kienle P, Kieser M, Slanger TE, Burmeister B, Kelsen D, Niedzwiecki D, Schuhmacher C, Urba S, van de Velde C, Walsh TN, Ychou M, Jensen K: Preoperative chemo(radio)therapy versus primary surgery for gastroesophageal adenocarcinoma: systematic review with meta-analysis combining individual patient and aggregate data. Eur J Cancer 2013, E-pub ahead of print.