Neovascularization is prominent in the chronic inflammatory lesions of Sjögren's syndrome

International Journal of Experimental Pathology

Volumn 95, Issue 2, 2014, Pages 131-137

  Sisto, Margherita ^a   Lisi, Sabrina ^a   Ingravallo, Giuseppe ^a   Lofrumento, Dario Domenico ^b   D'Amore, Massimo ^a   Ribatti, Domenico ^a  

^a UNIVERSITY OF BARI MEDICAL SCHOOL   (Italy)

^b UNIVERSITY OF SALENTO   (Italy)

Author keywords

Angiogenesis; CD31; CD68; Sj gren's syndrome; Tryptase

Indexed keywords

ADULT; AGED; ARTICLE; BIOPSY; CAPILLARY DENSITY; CHRONIC INFLAMMATION; CONTROLLED STUDY; HISTIOCYTE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MIDDLE AGED; MINOR SALIVA GLAND; NEOVASCULARIZATION (PATHOLOGY); PRIORITY JOURNAL; SJOEGREN SYNDROME; YOUNG ADULT;

ADULT; AGED; ANTIGENS, CD; ANTIGENS, CD31; ANTIGENS, CD34; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; FEMALE; HUMANS; INFLAMMATION; MACROPHAGES; MALE; MIDDLE AGED; NEOVASCULARIZATION, PATHOLOGIC; SALIVARY GLANDS, MINOR; SJOGREN'S SYNDROME;

EID: 84896137145     PISSN: 09599673     EISSN: 13652613     Source Type: Journal    
DOI: 10.1111/iep.12061     Document Type: Article

References (35)

1. Abu-Helu R.F., Dimitriou I.D., Kapsogeorgou E.K., Moutsopoulos H.M. & Manoussakis M.N. (2001) Induction of salivary gland epithelial cell injury in Sjogren's syndrome: in vitro assessment of T cell-derived cytokines and Fas protein expression. J. Autoimmun. 17, 141-153.
2. Bagli E., Xagorari A., Papetropoulos A., Murphy C. & Fotsis T. (2004) Angiogenesis in inflammation. Autoimmun. Rev. 3, S26.
3. Carmeliet P. (2005) Angiogenesis in life, disease and medicine. Nature 438, 932-936.
4. Carvalho J.F., Blank M. & Shoenfeld Y. (2007) Vascular endothelial growth factor (VEGF) in autoimmune diseases. J. Clin. Immunol. 27, 246-256.
5. Chisholm D.M. & Mason D.K. (1968) Labial salivary gland biopsy in Sjogren's disease. J. Clin. Path. 21, 656-660.
6. Figueroa-Vega N., Sanz-Cameno P., Moreno-Otero R., Sánchez-Madrid F., González-Amaro R. & Marazuela M. (2009) Serum levels of angiogenic molecules in autoimmune thyroid diseases and their correlation with laboratory and clinical features. J. Clin. Endocrinol. Metab. 94, 1145-1153.
7. Flisiak I., Zaniewski P., Rogalska M., Myśliwiec H., Jaroszewicz J. & Chodynicka B. (2013) Effect of psoriasis activity on VEGF and its soluble receptors concentrations in serum and plaque scales. Cytokine 61, 690.
8. Folkman J. (1995) Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat. Med. 1, 27-31.
9. Gallo A., Baldini C., Teos L., Mosca M., Bombardieri S. & Alevizos I. (2012) Emerging trends in Sjögren's syndrome: basic and translational research. Clin. Exp. Rheumatol. 30, 779-784.
10. Gerli R., Vaudo G. & Bocci E.B. (2010) Functional impairment of the arterial wall in primary Sjögren's syndrome: combined action of immunologic and inflammatory factors. Arthritis Care Res. 62, 712-718.
11. Hoeben A., Landuyt B., Highley M.S., Wildiers H., Van Oosterom A.T. & De Bruijn E.A. (2004) Vascular endothelial growth factor and angiogenesis. Pharmacol. Rev. 56, 549-580.
12. Ichikawa Y., Shimizu H., Yoshida M., Takaya M. & Arimori S. (1992) Accessory molecules expressed on the peripheral blood or synovial fluid T lymphocytes from patients with Sjögren's syndrome or rheumatoid arthritis. Clin. Exp. Rheumatol. 10, 447-454.
13. Koch A.E. & Distler O. (2007) Vasculopathy and disordered angiogenesis in selected rheumatic diseases: rheumatoid arthritis and systemic sclerosis. Arthritis Res. Ther. 9, S3.
14. Lewis C.E., Leek R., Harris A. & McGee J.O. (1995) Cytokine regulation of angiogenesis in breast cancer: the role of tumor-associated macrophages. J. Leukoc. Biol. 57, 747-751.
15. Lisi S., Sisto M., Soleti R. et al. (2007) Fcgamma receptors mediate internalization of anti-Ro and anti-La autoantibodies from Sjögren's syndrome and apoptosis in human salivary gland cell line A-253. J. Oral Pathol. Med. 36, 511-523.
16. Lisi S., Sisto M., Lofrumento D.D. et al. (2010) Pro-inflammatory role of anti-Ro/SSA autoantibodies through the activation of Furin-TACE-amphiregulin axis. J. Autoimmun. 35, 160-170.
17. Lisi S., Sisto M., Lofrumento D.D., D'Amore S. & D'Amore M. (2011) Advances in the understanding of the Fc gamma receptors-mediated autoantibodies uptake. Clin. Exp. Med. 11, 1-10.
18. Lisi S., Sisto M., D'Amore M., Lofrumento D.D. & Ribatti D. (2013a) Emerging avenues linking inflammation, angiogenesis and Sjögren's syndrome. Cytokine 61, 693-703.
19. Lisi S., Sisto M., Lofrumento D.D., D'Amore M., De Lucro R. & Ribatti D. (2013b) A potential role of the GRO-α/CXCR2 system in Sjögren's syndrome: regulatory effects of pro-inflammatory cytokines. Histochem. Cell Biol. 139, 371-379.
20. Majno G. (1998) Chronic inflammation: links with angiogenesis and wound healing. Am. J. Pathol. 153, 1035-1039.
21. Manoussakis M.N. & Kapsogeorgou E.K. (2007) The role of epithelial cells in the pathogenesis of Sjögren's syndrome. Clin. Rev. Allergy Immunol. 32, 225-230.
22. Maruotti N., Cantatore F.P., Crivellato E., Vacca A. & Ribatti D. (2007) Macrophages in rheumatoid arthritis. Histol. Histopathol. 22, 581-586.
23. Nucera S., Biziato D. & De Palma M. (2011) The interplay between macrophages and angiogenesis in development, tissue injury and regeneration. Int. J. Dev. Biol. 55, 495-503.
24. Ozdemir B.H., Ozdemir F.N., Gungen Y. & Haberal M. (2002) Role of macrophages and lymphocytes in the induction of neovascularization in renal allograft rejection. Am. J. Kidney Dis. 39, 347-353.
25. Ranieri G., Ammendola M., Patruno R. et al. (2009) Tryptase-positive mast cells correlate with angiogenesis in early breast cancer patients. Int. J. Oncol. 35, 115-120.
26. Ribatti D. & Crivellato E. (2012) "Sprouting angiogenesis", a reappraisal. Dev Biol. 15(372), 157-165.
27. Ribatti D., Crivellato E. & Vacca A. (2012) Inflammation and antiangiogenesis in cancer. Curr. Med. Chem. 19, 955-960.
28. Sens D.A., Hintz D.S., Rudisill M.T., Sens M.A. & Spicer S.S. (1985) Explant culture of human submandibular gland epithelial cells: evidence for ductal origin. Lab. Invest. 52, 559-567.
29. Sisto M., Lisi S., Lofrumento D.D., D'Amore M., Frassanito M.A. & Ribatti D. (2012a) Sjögren's syndrome pathological neovascularization is regulated by VEGF-A-stimulated TACE-dependent crosstalk between VEGFR2 and NF-κB. Genes Immun. 13, 411-420.
30. Sisto M., Lisi S., Lofrumento D.D., D'Amore M. & Ribatti D. (2012b) Neuropilin-1 is upregulated in Sjögren's syndrome and contributes to pathological neovascularization. Histochem. Cell Biol. 137, 669-677.
31. St Clair E.W., Angellilo J.C. & Singer K.H. (1992) Expression of cell-adhesion molecules in the salivary gland microenvironment of Sjögren's syndrome. Arthritis Rheum. 35, 62-66.
32. Sunderkotter C., Steinbrink K., Goebeler M., Bhardwaj R. & Sorg C. (1994) Macrophages and angiogenesis. J. Leukoc. Biol. 55, 410-422.
33. Taylor P.C. (2005) Serum vascular markers and vascular imaging in assessment of rheumatoid arthritis disease activity and response to therapy. Rheumatology (Oxford) 44, 721-728.
34. Tzioufas A.G. & Voulgarelis M. (2007) Update on Sjögren's syndrome autoimmune epithelitis: from classification to increased neoplasias. Best Pract. Res. Clin. Rheumatol. 21, 989-1010.
35. Vitali C., Bombardieri S., Jonsson R. et al. (2002) Classification criteria for Sjögren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group. European Study Group on Classification Criteria for Sjögren's Syndrome. Ann. Rheum. Dis. 61, 554-558.