Tumour-associated mutations of PA-TM-RING ubiquitin ligases RNF167/RNF13 identify the PA domain as a determinant for endosomal localization

Biochemical Journal

Volumn 459, Issue 1, 2014, Pages 27-36

  Van Dijk, Jesper R ^a   Yamazaki, Yasuo ^a   Palmer, Ruth H ^a  

^a UMEÅ UNIVERSITY   (Sweden)

Author keywords

E3 ubiquitin ligase; Goliath; Protease associated (PA) domain; RING domain; RING finger protein 167 (RNF167)

Indexed keywords

MUTANT PROTEIN; PROTEASE ASSOCIATED PROTEIN; PROTEINASE; RING FINGER PROTEIN; RING FINGER PROTEIN 13; RING FINGER PROTEIN 167; UBIQUITIN PROTEIN LIGASE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

ARTICLE; CANCER PATIENT; CELL GROWTH; CELL STRAIN HEK293; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOSOME; ENZYME ACTIVITY; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; HUMAN TISSUE; LOSS OF FUNCTION MUTATION; NEOPLASM; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; UBIQUITINATION; WILD TYPE;

AMINO ACID SEQUENCE; ENDOSOMES; GLYCOPROTEINS; HEK293 CELLS; HUMANS; MOLECULAR SEQUENCE DATA; PEPTIDE HYDROLASES; POINT MUTATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; TUMOR MARKERS, BIOLOGICAL; UBIQUITIN-PROTEIN LIGASES;

EID: 84896134009     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20131067     Document Type: Article

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