Tissue kallikrein mediates pro-inflammatory pathways and activation of protease-activated receptor-4 in proximal tubular epithelial cells

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Yiu, Wai Han ^a   Wong, Dickson W L ^a   Chan, Loretta Y Y ^a   Leung, Joseph C K ^a   Chan, Kwok Wah ^a   Lan, Hui Yao ^b   Lai, Kar Neng ^a   Tang, Sydney C W ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ADVANCED GLYCATION END PRODUCT; COLLAGEN TYPE 4; CONNECTIVE TISSUE GROWTH FACTOR; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; INTERLEUKIN 8; KALLIKREIN; KALLIKREIN 1; MACROPHAGE DERIVED CHEMOKINE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN P42; PROTEIN P44; PROTEINASE ACTIVATED RECEPTOR 4; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; CALCIUM; CYTOKINE; PRIMER DNA; PROTEASE-ACTIVATED RECEPTOR 4; PROTEINASE ACTIVATED RECEPTOR; THROMBIN RECEPTOR; TISSUE KALLIKREIN;

ADULT; AGED; ARTICLE; CALCIUM MOBILIZATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIABETIC NEPHROPATHY; ENZYME ACTIVATION; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; INFLAMMATION; KALLIKREIN KININ SYSTEM; KIDNEY TUBULE CELL; MALE; MIDDLE AGED; MOLECULAR MECHANICS; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; ANALYSIS OF VARIANCE; CELL CULTURE; CYTOLOGY; DIABETES MELLITUS; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; GENETICS; IMMUNOHISTOCHEMISTRY; KIDNEY PROXIMAL TUBULE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; WESTERN BLOTTING;

ANALYSIS OF VARIANCE; BLOTTING, WESTERN; CALCIUM; CELLS, CULTURED; CYTOKINES; DIABETES MELLITUS; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTERLEUKIN-8; KIDNEY TUBULES, PROXIMAL; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, PROTEINASE-ACTIVATED; RECEPTORS, THROMBIN; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TISSUE KALLIKREINS;

EID: 84896112806     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088894     Document Type: Article

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