Hyperglycemia induces abnormal gene expression in hematopoietic stem cells and their progeny in diabetic neuropathy

FEBS Letters

Volumn 588, Issue 6, 2014, Pages 1080-1086

  Katagi, Miwako ^a   Terashima, Tomoya ^a   Okano, Junko ^a   Urabe, Hiroshi ^a   Nakae, Yuki ^a   Ogawa, Nobuhiro ^a   Udagawa, Jun ^a   Maegawa, Hiroshi ^a   Matsumura, Kazuhiro ^a   Chan, Lawrence ^b   Kojima, Hideto ^a  

^a SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Cell cell fusion; Hematopoietic stem cell; Hyperglycemia; Neuropathy; Stem cell abnormalities

Indexed keywords

GLUCOSE; GREEN FLUORESCENT PROTEIN; INSULIN; STEM CELL ANTIGEN 1; STEM CELL FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CELL FUSION; CELL INTERACTION; CONTROLLED STUDY; CORRELATIONAL STUDY; DIABETIC NEUROPATHY; GENE EXPRESSION; GENETIC ASSOCIATION; GLUCOSE BLOOD LEVEL; HEMATOPOIETIC STEM CELL; HYPERGLYCEMIA; INSULIN GENE; MOUSE; NERVE INJURY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; PROGENY; PROTEIN LOCALIZATION; SPINAL GANGLION; TNF ALPHA GENE;

CELL-CELL FUSION; HEMATOPOIETIC STEM CELL; HYPERGLYCEMIA; NEUROPATHY; STEM CELL ABNORMALITIES;

ANIMALS; BONE MARROW; BONE MARROW TRANSPLANTATION; CELL FUSION; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; DIABETIC NEUROPATHIES; DIET, HIGH-FAT; GANGLIA, SPINAL; GENE EXPRESSION; HEMATOPOIETIC STEM CELLS; HYPERGLYCEMIA; INSULIN; MICE; MICE, INBRED C57BL; NEURONS; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; MUS;

EID: 84896082527     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2014.02.030     Document Type: Article

References (23)

1. T. Terashima, H. Kojima, M. Fujimiya, K. Matsumura, J. Oi, M. Hara, A. Kashiwagi, H. Kimura, H. Yasuda, and L. Chan The fusion of bone-marrow-derived proinsulin-expressing cells with nerve cells underlies diabetic neuropathy Proc. Natl. Acad. Sci. U.S.A. 102 35 2005 12525 12530
2. L. Chan, T. Terashima, H. Urabe, F. Lin, and H. Kojima Pathogenesis of diabetic neuropathy: bad to the bone Ann. N Y Acad. Sci. 1240 2011 70 76
3. I. Yamakawa, H. Kojima, T. Terashima, M. Katagi, J. Oi, H. Urabe, M. Sanada, H. Kawai, L. Chan, H. Yasuda, H. Maegawa, and H. Kimura Inactivation of TNF-α ameliorates diabetic neuropathy in mice Am. J. Physiol. Endocrinol. Metab. 301 5 2011 E844 E852
4. A. Petrelli, R. Di Fenza, M. Carvello, F. Gatti, A. Secchi, and P. Fiorina Strategies to reverse endothelial progenitor cell dysfunction in diabetes Exp. Diabetes Res. 2012 2012 471823
5. G.P. Fadini, and A. Avogaro It is all in the blood: the multifaceted contribution of circulating progenitor cells in diabetic complications Exp. Diabetes Res. 2012 2012 742976
6. J. Yellowlees Douglas, A.D. Bhatwadekar, S. Li Calzi, L.C. Shaw, D. Carnegie, S. Caballero, Q. Li, A.W. Stitt, M.K. Raizada, and M.B. Grant Bone marrow-CNS connections: implications in the pathogenesis of diabetic retinopathy Prog. Retin. Eye Res. 31 5 2012 481 494
7. H. Kojima, M. Fujimiya, K. Matsumura, T. Nakahara, M. Hara, and L. Chan Extrapancreatic insulin-producing cells in multiple organs in diabetes Proc. Natl. Acad. Sci. U.S.A. 101 8 2004 2458 2463
8. M. Fujimiya, H. Kojima, M. Ichinose, R. Arai, H. Kimura, A. Kashiwagi, and L. Chan Fusion of proinsulin-producing bone marrow-derived cells with hepatocytes in diabetes Proc. Natl. Acad. Sci. U.S.A. 104 10 2007 4030 4035
9. T. Terashima, H. Kojima, and L. Chan Bone marrow expression of poly(ADP-ribose) polymerase underlies diabetic neuropathy via hematopoietic-neuronal cell fusion FASEB J. 26 1 2012 295 308
10. S.H. Oh, T.M. Muzzonigro, S.H. Bae, J.M. LaPlante, H.M. Hatch, and B.E. Petersen Adult bone marrow-derived cells trans-differentiating into insulin-producing cells for the treatment of type I diabetes Lab. Invest. 84 5 2004 607 617
11. D.Q. Tang, Q. Wang, B.R. Burkhardt, S.A. Litherland, M.A. Atkinson, and L.J. Yang In vitro generation of functional insulin-producing cells from human bone marrow-derived stem cells, but long-term culture running risk of malignant transformation Am. J. Stem Cells 1 2 2012 114 127
12. F. González, N.S. Rote, J. Minium, and J.P. Kirwan In vitro evidence that hyperglycemia stimulates tumor necrosis factor-alpha release in obese women with polycystic ovary syndrome J. Endocrinol. 188 3 2006 521 529
13. S. Méndez-Ferrer, T.V. Michurina, F. Ferraro, A.R. Mazloom, B.D. Macarthur, S.A. Lira, D.T. Scadden, A. Ma'ayan, G.N. Enikolopov, and P.S. Frenette Mesenchymal and haematopoietic stem cells form a unique bone marrow niche Nature 466 7308 2010 829 834
14. D.S. Krause, D.T. Scadden, and F.I. Preffer The hematopoietic stem cell niche-home for friend and foe? Cytometry B Clin. Cytom. 84 1 2013 7 20
15. F. Ugarte, and E.C. Forsberg Haematopoietic stem cell niches: new insights inspire new questions EMBO J. 32 19 2013 2535 2547
16. D.Q. Tang, L.Z. Cao, B.R. Burkhardt, C.Q. Xia, S.A. Litherland, M.A. Atkinson, and L.J. Yang In vivo and in vitro characterization of insulin-producing cells obtained from murine bone marrow Diabetes 53 7 2004 1721 1732
17. I.G. Obrosova, F. Li, O.I. Abatan, M.A. Forsell, K. Komjáti, P. Pacher, C. Szabó, and M.J. Stevens Role of poly(ADP-ribose) polymerase activation in diabetic neuropathy Diabetes 53 3 2004 711 720
18. L. Zheng, C. Szabó, and T.S. Kern Poly(ADP-ribose) polymerase is involved in the development of diabetic retinopathy via regulation of nuclear factor-kappaB Diabetes 53 11 2004 2960 2967
19. D.J. Pearce, C.M. Ridler, C. Simpson, and D. Bonnet Multiparameter analysis of murine bone marrow side population cells Blood 103 7 2004 2541 2546
20. A. Orlandi, E. Chavakis, F. Seeger, M. Tjwa, A.M. Zeiher, and S. Dimmeler Long-term diabetes impairs repopulation of hematopoietic progenitor cells and dysregulates the cytokine expression in the bone marrow microenvironment in mice Basic Res. Cardiol. 105 6 2010 703 712
21. Y. Katayama, M. Battista, W.M. Kao, A. Hidalgo, A.J. Peired, S.A. Thomas, and P.S. Frenette Signals from the sympathetic nervous system regulate hematopoietic stem cell egress from bone marrow Cell 124 2 2006 407 421
22. A. El-Osta, D. Brasacchio, D. Yao, A. Pocai, P.L. Jones, R.G. Roeder, M.E. Cooper, and M. Brownlee Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia J. Exp. Med. 205 10 2008 2409 2417
23. D.M. Nathan, P.A. Cleary, J.Y. Backlund, S.M. Genuth, J.M. Lachin, T.J. Orchard, P. Raskin, and B. Zinman Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study Research Group. Intensive diabetes treatment and cardiovascular disease in patients with type 1 diabetes N. Engl. J. Med. 353 25 2005 2643 2653