메뉴 건너뛰기




Volumn 1, Issue 2, 2012, Pages 114-127

In vitro generation of functional insulin-producing cells from human bone marrow-derived stem cells, but long-term culture running risk of malignant transformation

Author keywords

Bone marrow; Differentiation; Insulin producing cells; Long term culture; Malignant transformation; Mesenchymal stem cells

Indexed keywords

ALPHA2 INTEGRIN; AMYLIN; BETA 2 MICROGLOBULIN; C PEPTIDE; EXENDIN 4; GLUCOSE; HERMES ANTIGEN; HLA ANTIGEN CLASS 1; INSULIN; MICROSOMAL AMINOPEPTIDASE; NEURO D PROTEIN; NEUROGENIC DIFFERENTIATION FACTOR; NEUROGENIN 3; NICOTINAMIDE; PEPTIDES AND PROTEINS; PROTEIN P16; PROTEIN P21; THY 1 ANTIGEN; TRANSCRIPTION FACTOR PAX4; TRANSCRIPTION FACTOR PDX 1; UNCLASSIFIED DRUG;

EID: 84876101062     PISSN: None     EISSN: 21604150     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (51)

References (41)
  • 1
    • 0035928391 scopus 로고    scopus 로고
    • Type 1 diabetes: New perspectives on disease pathogenesis and treatment
    • Atkinson MA, Eisenbarth GS. Type 1 diabetes: new perspectives on disease pathogenesis and treatment. Lancet 2001; 358: 221-229.
    • (2001) Lancet , vol.358 , pp. 221-229
    • Atkinson, M.A.1    Eisenbarth, G.S.2
  • 2
    • 79952180946 scopus 로고    scopus 로고
    • Evolution of β-Cell Replacement Therapy in Diabetes Mellitus: Pancreas Transplantation
    • Jahansouz C, Kumer SC, Ellenbogen M, Brayman KL. Evolution of β-Cell Replacement Therapy in Diabetes Mellitus: Pancreas Transplantation. Diabetes Technol Ther 2011; 13: 395-418.
    • (2011) Diabetes Technol Ther , vol.13 , pp. 395-418
    • Jahansouz, C.1    Kumer, S.C.2    Ellenbogen, M.3    Brayman, K.L.4
  • 4
    • 81455143613 scopus 로고    scopus 로고
    • Evaluation of segmental pancreatic function using 11C-methionine positron emission tomography for safe living donor operation of pancreas transplantation
    • Otsuki K, Yoshikawa K, Kenmochi T, Maruyama M, Akutsu N, Iwashita C, Ito T, Asano T. Evaluation of segmental pancreatic function using 11C-methionine positron emission tomography for safe living donor operation of pancreas transplantation. Transplant Proc 2011; 43: 3273-3276.
    • (2011) Transplant Proc , vol.43 , pp. 3273-3276
    • Otsuki, K.1    Yoshikawa, K.2    Kenmochi, T.3    Maruyama, M.4    Akutsu, N.5    Iwashita, C.6    Ito, T.7    Asano, T.8
  • 5
    • 70149102891 scopus 로고    scopus 로고
    • Pancreas transplant outcomes for United States (US) cases as reported to the United Network for Organ Sharing (UNOS) and the International Pancreas Transplant Registry (IPTR)
    • Gruessner AC, Sutherland DE. Pancreas transplant outcomes for United States (US) cases as reported to the United Network for Organ Sharing (UNOS) and the International Pancreas Transplant Registry (IPTR) Clin Transpl. 2008; 45-56.
    • (2008) Clin Transpl , pp. 45-56
    • Gruessner, A.C.1    Sutherland, D.E.2
  • 6
    • 78650664975 scopus 로고    scopus 로고
    • Pancreas transplantation
    • Han DJ, Sutherland DE. Pancreas transplantation. Gut Liver 2010; 4: 450-465.
    • (2010) Gut Liver , vol.4 , pp. 450-465
    • Han, D.J.1    Sutherland, D.E.2
  • 8
    • 84555203780 scopus 로고    scopus 로고
    • Generation of neural stem celllike cells from bone marrow-derived human mesenchymal stem cells
    • Ma K, Fox L, Shi G, Shen J, Liu Q, Pappas JD, Cheng J, Qu T. Generation of neural stem celllike cells from bone marrow-derived human mesenchymal stem cells. Neurol Res 2011; 33: 1083-1093.
    • (2011) Neurol Res , vol.33 , pp. 1083-1093
    • Ma, K.1    Fox, L.2    Shi, G.3    Shen, J.4    Liu, Q.5    Pappas, J.D.6    Cheng, J.7    Qu, T.8
  • 10
    • 83655182660 scopus 로고    scopus 로고
    • Galectin-3 enhances proliferation and angiogenesis of endothelial cells differentiated from bone marrow mesenchymal stem cells
    • Wan SY, Zhang TF, Ding Y. Galectin-3 enhances proliferation and angiogenesis of endothelial cells differentiated from bone marrow mesenchymal stem cells. Transplant Proc 2011; 43: 3933-3938.
    • (2011) Transplant Proc , vol.43 , pp. 3933-3938
    • Wan, S.Y.1    Zhang, T.F.2    Ding, Y.3
  • 13
    • 78650511231 scopus 로고    scopus 로고
    • CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells
    • Wei Y, Chen YH, Li LY, Lang J, Yeh SP, Shi B, Yang CC, Yang JY, Lin CY, Lai CC, Hung MC. CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells. Nat Cell Biol 2011; 13: 87-94.
    • (2011) Nat Cell Biol , vol.13 , pp. 87-94
    • Wei, Y.1    Chen, Y.H.2    Li, L.Y.3    Lang, J.4    Yeh, S.P.5    Shi, B.6    Yang, C.C.7    Yang, J.Y.8    Lin, C.Y.9    Lai, C.C.10    Hung, M.C.11
  • 15
    • 0037364517 scopus 로고    scopus 로고
    • In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion
    • Ianus A, Holz GG, Theise ND, Hussain MA. In vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion. J Clin Invest 2003; 111: 843-850.
    • (2003) J Clin Invest , vol.111 , pp. 843-850
    • Ianus, A.1    Holz, G.G.2    Theise, N.D.3    Hussain, M.A.4
  • 18
    • 1442326000 scopus 로고    scopus 로고
    • No evidence for significant transdifferentiation of bone marrow into pancreatic beta-cells in vivo
    • Lechner A, Yang YG, Blacken RA, Wang L, Nolan AL, Habener JF. No evidence for significant transdifferentiation of bone marrow into pancreatic beta-cells in vivo. Diabetes 2004; 53: 616-623.
    • (2004) Diabetes , vol.53 , pp. 616-623
    • Lechner, A.1    Yang, Y.G.2    Blacken, R.A.3    Wang, L.4    Nolan, A.L.5    Habener, J.F.6
  • 20
    • 2942594624 scopus 로고    scopus 로고
    • Adult bone marrowderived cells trans-differentiating into insulinproducing cells for the treatment of type I diabetes
    • Oh SH, Muzzonigro TM, Bae SH, LaPlante JM, Hatch HM, Petersen BE. Adult bone marrowderived cells trans-differentiating into insulinproducing cells for the treatment of type I diabetes. Lab Invest 2004; 84: 607-617.
    • (2004) Lab Invest , vol.84 , pp. 607-617
    • Oh, S.H.1    Muzzonigro, T.M.2    Bae, S.H.3    Laplante, J.M.4    Hatch, H.M.5    Petersen, B.E.6
  • 21
    • 0034006587 scopus 로고    scopus 로고
    • Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and - independent glucosestimulated insulin secretion
    • Hohmeier HE, Mulder H, Chen G, Henkel-Rieger R, Prentki M, Newgard CB. Isolation of INS-1-derived cell lines with robust ATP-sensitive K+ channel-dependent and - independent glucosestimulated insulin secretion. Diabetes 2000; 49: 424-430.
    • (2000) Diabetes , vol.49 , pp. 424-430
    • Hohmeier, H.E.1    Mulder, H.2    Chen, G.3    Henkel-Rieger, R.4    Prentki, M.5    Newgard, C.B.6
  • 23
    • 0035525779 scopus 로고    scopus 로고
    • Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells
    • Reyes M, Lund T, Lenvik T, Aguiar D, Koodie L, Verfaillie CM. Purification and ex vivo expansion of postnatal human marrow mesodermal progenitor cells. Blood 2001; 98: 2615-2625.
    • (2001) Blood , vol.98 , pp. 2615-2625
    • Reyes, M.1    Lund, T.2    Lenvik, T.3    Aguiar, D.4    Koodie, L.5    Verfaillie, C.M.6
  • 24
  • 25
    • 9444255761 scopus 로고    scopus 로고
    • High glucose is necessary for complete maturation of pdx-1-vp16-expressing hepatic cells into functional insulin-producing cells
    • Cao LZ, Tang DQ, Horb ME, Li SW, Yang LJ. High glucose is necessary for complete maturation of pdx-1-vp16-expressing hepatic cells into functional insulin-producing cells. Diabetes 2004; 53: 3168-3178.
    • (2004) Diabetes , vol.53 , pp. 3168-3178
    • Cao, L.Z.1    Tang, D.Q.2    Horb, M.E.3    Li, S.W.4    Yang, L.J.5
  • 27
    • 0037213587 scopus 로고    scopus 로고
    • Gene expression cascades in pancreatic development
    • Wilson ME, Scheel D, German MS. Gene expression cascades in pancreatic development. Mech Dev 2003; 120(1):65-80.
    • (2003) Mech Dev , vol.120 , Issue.1 , pp. 65-80
    • Wilson, M.E.1    Scheel, D.2    German, M.S.3
  • 28
    • 0033607147 scopus 로고    scopus 로고
    • In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis
    • Nuovo GJ, Plaia TW, Belinsky SA, Baylin SB, Herman JG. In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis. Proc Natl Acad Sci USA 1999; 96: 12754-12759.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 12754-12759
    • Nuovo, G.J.1    Plaia, T.W.2    Belinsky, S.A.3    Baylin, S.B.4    Herman, J.G.5
  • 31
    • 0034100823 scopus 로고    scopus 로고
    • Reversal of insulindependent diabetes using islets generated in vitro from pancreatic stem cells
    • Ramiya VK, Maraist M, Arfors KE, Schatz DA, Peck AB, Cornelius JG. Reversal of insulindependent diabetes using islets generated in vitro from pancreatic stem cells. Nat Med 2000; 6: 278-282.
    • (2000) Nat Med , vol.6 , pp. 278-282
    • Ramiya, V.K.1    Maraist, M.2    Arfors, K.E.3    Schatz, D.A.4    Peck, A.B.5    Cornelius, J.G.6
  • 32
    • 0037628628 scopus 로고    scopus 로고
    • Glucagonlike peptide 1 (1-37) converts intestinal epithelial cells into insulin-producing cells
    • Suzuki A, Nakauchi H, Taniguchi H. Glucagonlike peptide 1 (1-37) converts intestinal epithelial cells into insulin-producing cells. Proc Natl Acad Sci USA 2003; 100: 5034-5039.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 5034-5039
    • Suzuki, A.1    Nakauchi, H.2    Taniguchi, H.3
  • 33
    • 0033979603 scopus 로고    scopus 로고
    • Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice
    • Soria B, Roche E, Berna G, Leon-Quinto T, Reig JA, Martin F. Insulin-secreting cells derived from embryonic stem cells normalize glycemia in streptozotocin-induced diabetic mice. Diabetes 2000; 49: 157-162.
    • (2000) Diabetes , vol.49 , pp. 157-162
    • Soria, B.1    Roche, E.2    Berna, G.3    Leon-Quinto, T.4    Reig, J.A.5    Martin, F.6
  • 34
    • 0035906902 scopus 로고    scopus 로고
    • Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets
    • Lumelsky N, Blondel O, Laeng P, Velasco I, Ravin R, McKay R. Differentiation of embryonic stem cells to insulin-secreting structures similar to pancreatic islets. Science 2001; 292: 1389-1394.
    • (2001) Science , vol.292 , pp. 1389-1394
    • Lumelsky, N.1    Blondel, O.2    Laeng, P.3    Velasco, I.4    Ravin, R.5    McKay, R.6
  • 36
    • 0033513455 scopus 로고    scopus 로고
    • Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats
    • Xu G, Stoffers DA, Habener JF, Bonner-Weir S. Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats. Diabetes 1999; 48: 2270-2276.
    • (1999) Diabetes , vol.48 , pp. 2270-2276
    • Xu, G.1    Stoffers, D.A.2    Habener, J.F.3    Bonner-Weir, S.4
  • 37
    • 0037414781 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis
    • Li Y, Hansotia T, Yusta B, Ris F, Halban PA, Drucker DJ. Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis. J Biol Chem 2003; 278: 471-478.
    • (2003) J Biol Chem , vol.278 , pp. 471-478
    • Li, Y.1    Hansotia, T.2    Yusta, B.3    Ris, F.4    Halban, P.A.5    Drucker, D.J.6
  • 38
    • 17944385649 scopus 로고    scopus 로고
    • Activation of Reg gene, a gene for insulin-producing beta - cell regeneration: Poly(ADP-ribose) polymerase binds Reg promoter and regulates the transcription by autopoly(ADP-ribosylation
    • Akiyama T, Takasawa S, Nata K, Kobayashi S, Abe M, Shervani NJ, Ikeda T, Nakagawa K, Unno M, Matsuno S, Okamoto H. Activation of Reg gene, a gene for insulin-producing beta - cell regeneration: poly(ADP-ribose) polymerase binds Reg promoter and regulates the transcription by autopoly(ADP-ribosylation. Proc Natl Acad Sci USA 2001; 98: 48-53.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 48-53
    • Akiyama, T.1    Takasawa, S.2    Nata, K.3    Kobayashi, S.4    Abe, M.5    Shervani, N.J.6    Ikeda, T.7    Nakagawa, K.8    Unno, M.9    Matsuno, S.10    Okamoto, H.11
  • 41
    • 82555187982 scopus 로고    scopus 로고
    • Spontaneous transformation of adult mesenchymal stem cells from cynomolgus macaques in vitro
    • Ren Z, Wang J, Zhu W, Guan Y, Zou C, Chen Z, Zhang YA. Spontaneous transformation of adult mesenchymal stem cells from cynomolgus macaques in vitro. Exp Cell Res 2011; 317: 2950-2957.
    • (2011) Exp Cell Res , vol.317 , pp. 2950-2957
    • Ren, Z.1    Wang, J.2    Zhu, W.3    Guan, Y.4    Zou, C.5    Chen, Z.6    Zhang, Y.A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.