Endocellular regulation by free radicals and hydrogen peroxide: Key determinants of the inflammatory response

Inflammopharmacology

Volumn 22, Issue 2, 2014, Pages 69-72

  Vitetta, Luis ^a,b   Linnane, Anthony W ^a  

^a Medlab   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Antioxidants; Free radicals; Inflammation; Metabolome; Pro oxidants; Protein oxidations; Reactive nitrogen species; Reactive oxygen species

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; FREE RADICAL; HYDROGEN PEROXIDE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE;

CELL METABOLISM; CELLULAR PARAMETERS; CELLULAR SECRETION; CHRONIC DISEASE; DISEASE ASSOCIATION; DISEASE COURSE; HUMAN; INFLAMMATION; MACROMOLECULE; METABOLOME; MOLECULAR DYNAMICS; NOTE; OXIDATIVE STRESS; PHYSIOLOGICAL PROCESS; PRIORITY JOURNAL; REGULATORY MECHANISM; SECOND MESSENGER; SYSTEMIC DISEASE;

ANTIOXIDANTS; FREE RADICALS; HUMANS; HYDROGEN PEROXIDE; INFLAMMATION; OXIDATIVE STRESS; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES;

EID: 84896071293     PISSN: 09254692     EISSN: 15685608     Source Type: Journal    
DOI: 10.1007/s10787-014-0199-7     Document Type: Note

References (17)

1. Bota DA, Van Remmen H, Davies KJ (2002) Modulation of Lon protease activity and aconitase turnover during aging and oxidative stress. FEBS Lett 532(1-2):103-106 (Pubitemid 35375875)
2. Bota DA, Ngo JK, Davies KJ (2005) Down regulation of the human Lon protease impairs mitochondrial structure and function and causes cell death. Free Radic Biol Med 38(5):665-677 (Pubitemid 40416862)
3. Farout L, Friguet B (2006) Proteasome function in aging and oxidative stress: implications in protein maintenance failure. Antioxid Redox Signal 8:205-216 (Pubitemid 43324547)
4. Khansari N, Shakiba Y, Mahmoudi M (2009) Chronic inflammation and oxidative stress as a major cause of age-related diseases and cancer. Recent Pat Inflamm Allergy Drug Discov 3(1):73-80
5. Leusen JH, de Klein A, Hilarius PM, Ahlin A, Palmblad J, Smith CI, Diekmann D, Hall A, Verhoeven AJ, Roos D (1996) Disturbed interaction of p21-rac with mutated p67-phox causes chronic granulomatous disease. J Exp Med 184(4):1243-1249 (Pubitemid 26354679)
6. Linnane AW, Eastwood H (2006) Cellular redox regulation and prooxidant signaling systems: a new perspective on the free radical theory of aging. Ann N Y Acad Sci 1067:47-55 (Pubitemid 43806309)
7. Linnane AW, Kios M, Vitetta L (2007a) Healthy aging: regulation of the metabolome by cellular redox modulation and prooxidant signaling systems: the essential roles of superoxide anion and hydrogen peroxide. Biogerontology 8(5):445-467 (Pubitemid 47365335)
8. Linnane AW, Kios M, Vitetta L (2007b) The essential roles of superoxide radical and nitric oxide formation for healthy aging. Mitochondrion 7:1-5 (Pubitemid 46351968)
9. Meiners S, Heyken D, Weller A, Ludwig A, Stangl K, Kloetzel PM, Kruger E (2003) Inhibition of proteasome induces concerted expression of proteasome genes and de novo formation of mammalian proteasomes. J Biol Chem 278:21517-21525 (Pubitemid 36792549)
10. Mitchell P (1978) Nobel Lecture. http://www.nobelprize.org/nobel-prizes/ chemistry/laureates/1978/mitchell-lecture.pdf. Accessed Jan 2014
11. Singel DJ, Stamler JS (2005) Chemical physiology of blood flow regulation by red blood cells: the role of nitric oxide and S-nitrohemoglobin. Ann Rev Physiol 67:99-145 (Pubitemid 40404487)
12. Stolze IP, Mole DR, Ratcliffe PJ (2006) Regulation of HIF: prolyl hydroxylases. Novartis Found Symp 272:15-25
13. Sun H, Gao J, Ferrington DA, Biesiada H, Williams TD, Squier TC (1999) Repair of oxidized calmodulin by methionine sulfoxide reductase restores ability to activate the plasma membrane Ca-ATPase. Biochemistry 38:105-112 (Pubitemid 29035676)
14. Vitetta L, Linnane AW, Gobe GC (2013) From the gastrointestinal tract (GIT) to the kidneys:live bacterial cultures (probiotics) mediating reductions of uremic toxin levels via free radical signaling. Toxins (Basel) 5(11):2042-2057
15. Whitehouse MW (1968) Molecular pharmacology of anti-inflammatory drugs: some possible mechanisms of action at the biochemical level. Biochem Pharmacol 17 Suppl 1:293-307
16. Yin D, Sun H, Weaver RF, Squier TC (1999) Nonessential role for methionines in the productive association between calmodulin and the plasma membrane Ca-ATPase. Biochemistry 38:13654-13660
17. Yin D, Kuczera K, Squier TC (2000) The sensitivity of carboxylterminal methionines in calmodulin isoforms to oxidation by H2O2 modulates the ability to activate the plasma membrane Ca-ATPase. Chem Res Toxicol 13:103-110 (Pubitemid 30115549)