Sensitivity of different generations and developmental stages in studies on reproductive toxicity

Toxicology Letters

Volumn 226, Issue 2, 2014, Pages 245-255

  Schulz, F ^a   Batke, M ^a   Mangelsdorf, I ^a   Pohlenz Michel, C ^a   Simetska, N ^a   Lewin, G ^a  

^a FRAUNHOFER INSTITUTE FOR TOXICOLOGY AND EXPERIMENTAL MEDICINE   (Germany)

Author keywords

FeDTex database; LOEL; Multi generation reproductive toxicity study; NOEL; Reproductive toxicology; Risk assessment

Indexed keywords

ANIMAL EXPERIMENT; ANOGENITAL DISTANCE; ARTICLE; BODY WEIGHT; COMPARATIVE STUDY; COMPUTER MODEL; CORRELATION ANALYSIS; DATA BASE; DEVELOPMENTAL STAGE; DEVELOPMENTAL TOXICITY; DYSTOCIA; FERTILITY; GROWTH RETARDATION; IN VITRO STUDY; KIDNEY; LIVER; NONHUMAN; ORGAN WEIGHT; PRENATAL DEVELOPMENT; PRIORITY JOURNAL; PROGENY; PROSTATE; PUERPERIUM; QUANTITATIVE ANALYSIS; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REPRODUCTIVE TOXICITY; RISK ASSESSMENT; SENSITIVITY ANALYSIS; SEXUAL MATURATION; SPERM; TESTIS DESCENT; WEIGHT CHANGE;

FEDTEX DATABASE; LOEL; MULTI-GENERATION REPRODUCTIVE TOXICITY STUDY; NOEL; REPRODUCTIVE TOXICOLOGY; RISK ASSESSMENT;

ANIMALS; BODY WEIGHT; BREEDING; DATABASES, FACTUAL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FERTILITY; HUMANS; MALE; MICE; NO-OBSERVED-ADVERSE-EFFECT LEVEL; ORGAN SIZE; RABBITS; RATS; REPRODUCTION; RISK ASSESSMENT; SEXUAL MATURATION; TOXICITY TESTS;

EID: 84896053309     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2014.01.045     Document Type: Article

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