-
2
-
-
0003302467
-
Use of quantitative structure-activity relationships in international decision-making frameworks to predict health effects of chemical substances
-
Cronin M.T.D., Jaworska J.S., Walker J.D., Comber M.H.I., Watts C.D., and Worth A.P. Use of quantitative structure-activity relationships in international decision-making frameworks to predict health effects of chemical substances. Environ. Health Perspect. 111 (2003) 1391-1401
-
(2003)
Environ. Health Perspect.
, vol.111
, pp. 1391-1401
-
-
Cronin, M.T.D.1
Jaworska, J.S.2
Walker, J.D.3
Comber, M.H.I.4
Watts, C.D.5
Worth, A.P.6
-
4
-
-
33750606613
-
-
Danish EPA, 2001. Report on the advisory list for self classification of dangerous substances. Danish Environmental Protection Agency. Environmental Project No. 636 2001, Copenhagen, pp. 39
-
-
-
-
5
-
-
33750626789
-
-
DFG (Deutsche Forschungsgemeinschaft, Ed.), 1991-2003. Occupational Toxicants: Critical Data Evaluation for MAK Values and Classification of Carcinogens. VCH, Weinheim, Cambridge, New York.
-
-
-
-
6
-
-
33750626640
-
-
ECETOC, 1995. The toxicology of glycol ethers and its relevance to man. European Centre for Ecotoxicology and Toxicology of Chemicals, Technical Report No. 64, Brussels, pp. 350.
-
-
-
-
7
-
-
0043132440
-
Methods for reliability and uncertainty assessment, and applicability evaluations of classification- and regression-based QSARs
-
Eriksson L., Jaworska J., Worth A., Cronin M., McDowell R., and Gramatica P. Methods for reliability and uncertainty assessment, and applicability evaluations of classification- and regression-based QSARs. Environ. Health Perspect. 111 10 (2003) 1361-1375
-
(2003)
Environ. Health Perspect.
, vol.111
, Issue.10
, pp. 1361-1375
-
-
Eriksson, L.1
Jaworska, J.2
Worth, A.3
Cronin, M.4
McDowell, R.5
Gramatica, P.6
-
8
-
-
0028236377
-
Toxicity and ecotoxicity of sulfonic acids: Structure-activity relationship
-
Greim H.J., Ahlers J., Bias R., Broecker B., Hollander H., Gelbke H.-P., Klimisch H.-J., Mangelsdorf I., Paetz A., and Schön N. Toxicity and ecotoxicity of sulfonic acids: Structure-activity relationship. Chemosphere 28 (1994) 2203-2236
-
(1994)
Chemosphere
, vol.28
, pp. 2203-2236
-
-
Greim, H.J.1
Ahlers, J.2
Bias, R.3
Broecker, B.4
Hollander, H.5
Gelbke, H.-P.6
Klimisch, H.-J.7
Mangelsdorf, I.8
Paetz, A.9
Schön, N.10
-
9
-
-
0029153096
-
Assessment of structurally related chemicals: toxicity and ecotoxicity of acrylic acid and acrylic acid alkyl esters (acrylates), methacrylic acid and methacrylic acid alkyl esters (methacrylates)
-
Greim H.J., Ahlers J., Bias R., Broecker B., Hollander H., Gelbke H.-P., Jacobi S., Klimisch H.-J., Mangelsdorf I., and Mayr V. Assessment of structurally related chemicals: toxicity and ecotoxicity of acrylic acid and acrylic acid alkyl esters (acrylates), methacrylic acid and methacrylic acid alkyl esters (methacrylates). Chemosphere 31 (1995) 2637-2659
-
(1995)
Chemosphere
, vol.31
, pp. 2637-2659
-
-
Greim, H.J.1
Ahlers, J.2
Bias, R.3
Broecker, B.4
Hollander, H.5
Gelbke, H.-P.6
Jacobi, S.7
Klimisch, H.-J.8
Mangelsdorf, I.9
Mayr, V.10
-
10
-
-
33750628677
-
-
Kalberlah, F.; Schneider, K. (1998) Examination of the data as the basis for the quantification of extrapolation factors. Wirtschaftsverlag NW Verlag für neue Wissenschaft GmbH. Bremerhaven (Schriftenreihe der Bundesanstalt für Arbeitsschutz und Arbeitsmedizin: Forschungsbericht, Fb 796), ISBN: 3-89701-105-0, 208 pages,.
-
-
-
-
11
-
-
10744227159
-
Structure-based Thresholds of Toxicological Concern (TTC): Guidance for application to substances present at low levels in the diet
-
Kroes R., Renwick A.G., Cheeseman M., Kleiner J., Mangelsdorf I., Piersma A., Schilter B., Schlatter J., von Schothorst F., Vos J.G., and Würtzen G. Structure-based Thresholds of Toxicological Concern (TTC): Guidance for application to substances present at low levels in the diet. Food and Chemical Toxicology 42 1 (2004) 65-83
-
(2004)
Food and Chemical Toxicology
, vol.42
, Issue.1
, pp. 65-83
-
-
Kroes, R.1
Renwick, A.G.2
Cheeseman, M.3
Kleiner, J.4
Mangelsdorf, I.5
Piersma, A.6
Schilter, B.7
Schlatter, J.8
von Schothorst, F.9
Vos, J.G.10
Würtzen, G.11
-
12
-
-
0029831688
-
Compact and molecular structure in toxicity assessment: a prospective evaluation of 30 chemicals currently being tested for rodent carcinogenicity by the NCI/NTP
-
Lewis D.V., Ioannides C., and Parke D. Compact and molecular structure in toxicity assessment: a prospective evaluation of 30 chemicals currently being tested for rodent carcinogenicity by the NCI/NTP. Environ. Health Perspect. Suppl. 104 5 (1996) 1011-1016
-
(1996)
Environ. Health Perspect. Suppl.
, vol.104
, Issue.5
, pp. 1011-1016
-
-
Lewis, D.V.1
Ioannides, C.2
Parke, D.3
-
13
-
-
0037716854
-
Some aspects relating to the evaluation of the effects of chemicals on male fertility
-
Mangelsdorf I., Buschmann J., and Orthen B. Some aspects relating to the evaluation of the effects of chemicals on male fertility. Regulatory Toxicology and Pharmacology 37 (2003) 356-369
-
(2003)
Regulatory Toxicology and Pharmacology
, vol.37
, pp. 356-369
-
-
Mangelsdorf, I.1
Buschmann, J.2
Orthen, B.3
-
14
-
-
0033935598
-
The practice of structure activity relationships (SAR) in toxicology
-
McKinney J., Richard A., Waller C., Newman M., and Gerberick F. The practice of structure activity relationships (SAR) in toxicology. Toxicol. Sci. 56 (2000) 8-17
-
(2000)
Toxicol. Sci.
, vol.56
, pp. 8-17
-
-
McKinney, J.1
Richard, A.2
Waller, C.3
Newman, M.4
Gerberick, F.5
-
15
-
-
33750624548
-
-
Merck Index, 1996. The Merck Index: an encyclopedia of chemicals, drugs, and biologicals (annual) by Budavari, S. et al. (Eds.), 12th ed., CRC Press, Boca Raton, FL.
-
-
-
-
16
-
-
0029082966
-
Assessment of effect levels of chemicals from quantitative structure-activity relationship (QSAR) models. I. Chronic lowest-observed-adverse-effect level (LOAEL).
-
Mumtaz M.M., Knauf L.A., Reismann D.J., Peirano W.B., DeRosa C.T., Gombar V.K., Enslein K., Carter J.R., Blake B.W., Huque K.I., and Ramanujam V.M.S. Assessment of effect levels of chemicals from quantitative structure-activity relationship (QSAR) models. I. Chronic lowest-observed-adverse-effect level (LOAEL). Toxicol. Lett. 79 (1995) 131-143
-
(1995)
Toxicol. Lett.
, vol.79
, pp. 131-143
-
-
Mumtaz, M.M.1
Knauf, L.A.2
Reismann, D.J.3
Peirano, W.B.4
DeRosa, C.T.5
Gombar, V.K.6
Enslein, K.7
Carter, J.R.8
Blake, B.W.9
Huque, K.I.10
Ramanujam, V.M.S.11
-
17
-
-
0029974283
-
Thresholds of toxicological concern based on structure-activity relationships
-
Munro I., Ford R., Kennepohl E., and Sprenger J. Thresholds of toxicological concern based on structure-activity relationships. Drug Metab. Rev. 28 1-2 (1996) 209-217
-
(1996)
Drug Metab. Rev.
, vol.28
, Issue.1-2
, pp. 209-217
-
-
Munro, I.1
Ford, R.2
Kennepohl, E.3
Sprenger, J.4
-
18
-
-
0030250802
-
Correlation of structural class with no-observed-effect levels: A proposal for establishing a threshold of concern
-
Munro I., Ford R., Kennepohl E., and Sprenger J. Correlation of structural class with no-observed-effect levels: A proposal for establishing a threshold of concern. Food Chem. Toxicol. 34 (1996) 829-867
-
(1996)
Food Chem. Toxicol.
, vol.34
, pp. 829-867
-
-
Munro, I.1
Ford, R.2
Kennepohl, E.3
Sprenger, J.4
-
19
-
-
1042265247
-
Approaches to measure chemical similarity-a review
-
Nikolova N., and Jaworska J. Approaches to measure chemical similarity-a review. QSAR Comb. Sci. 22 (2003) 1006-10026
-
(2003)
QSAR Comb. Sci.
, vol.22
, pp. 1006-10026
-
-
Nikolova, N.1
Jaworska, J.2
-
20
-
-
0343990062
-
Commentary on the application of (Q)SAR to the toxicological evaluation of existing chemicals
-
Pölloth C., and Mangelsdorf I. Commentary on the application of (Q)SAR to the toxicological evaluation of existing chemicals. Chemosphere 35 11 (1997) 2525-2542
-
(1997)
Chemosphere
, vol.35
, Issue.11
, pp. 2525-2542
-
-
Pölloth, C.1
Mangelsdorf, I.2
-
21
-
-
0032435458
-
Commercial toxicology prediction systems: a regulatory perspective
-
Richard A.M. Commercial toxicology prediction systems: a regulatory perspective. Toxicol. Lett. 103 (1998) 611-616
-
(1998)
Toxicol. Lett.
, vol.103
, pp. 611-616
-
-
Richard, A.M.1
-
22
-
-
33750619649
-
-
RIVM, 1999. (Q)SARs for human toxicological endpoints: a literature search., Research for man and environment, RIVM report 601516.001; February 1999, Bilthoven, pp. 65
-
-
-
-
23
-
-
33750609934
-
-
TOPKAT, 2003, http://www.accelrys.com/products/topkat/ratchro.html.
-
-
-
-
24
-
-
33750619014
-
-
US EPA, 2000. The use of structure-activity relationships (SAR) in the High Production Volume Chemicals Challenge Program. Washington, DC, pp. 20, http://www.epa.gov/chemrtk/sarfinl1.htm..
-
-
-
|