Effect of simulated microgravity on the activity of regulatory enzymes of glycolysis and gluconeogenesis in mice liver

Microgravity Science and Technology

Volumn 25, Issue 5, 2014, Pages 303-309

  Ramirez, Joaquin ^a   Periyakaruppan, Adaikkappan ^a   Sarkar, Shubhashish ^a   Ramesh, Govindarajan T ^a,b   Sharma, S Chidananda ^a,c  

^a TEXAS SOUTHERN UNIVERSITY   (United States)

^b NORFOLK STATE UNIVERSITY   (United States)

^c BANGALORE UNIVERSITY   (India)

Author keywords

Hexokinase; LDH; PEPCK; PFK 2; Simulated microgravity

Indexed keywords

ENZYME ACTIVITY; MAMMALS; METABOLISM; MICROGRAVITY; MICROGRAVITY PROCESSING; PATHOLOGY; UNLOADING;

HEXOKINASES; LDH; PEPCK; PFK-2; SIMULATED MICROGRAVITY;

COMPUTER SIMULATION;

EID: 84895920544     PISSN: 09380108     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12217-013-9356-7     Document Type: Article

References (25)

1. Ash, D.E., Emig, F.A., Chowdhury, S.A., Satoh, Y., Schramm, V.L.: Mammalian and avian liver phosphoenolpyruvate carboxykinase. Alternate substrates and inhibition by analogues of oxaloacetate. J. Biol. Chem. 265, 7377-7384 (1990)
2. Bikle, D.D., Halloran, B.P.: The response of bone to unloading. J. Bone Miner. Metab. 17, 233-244 (1999)
3. Bradford, M.M.: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye-binding. Anal. Biochem. 72, 248-254 (1976)
4. Dai, K., Wang, Y., Yan, R., Shi, Q., Wang, Z., Yuan, Y., Cheng, H., Li, S., Fan, Y., Zhuang, F.: Effects of microgravity and hypergravity on platelet functions. Thromb. Haemost. 101, 902-910 (2009)
5. Ding, Y., Tang, J., Zou, J., She, R., Wang, Y., Yue, Z., Tian, J., Xia, K., Yin, J., Wang, D.: The effect of microgravity on tissue structure and function of rat testis. Braz. J. Med. Biol. Res. 44, 1243-1250 (2011)
6. Fitts, R.H., Riley, D.R., Widrick, J.J.: Physiology of a microgravity environment invited review: microgravity and muscle. J. Appl. Physiol. 89, 823-839 (2000)
7. Fitts, R.H., Riley, D.R., Widrick, J.J.: Functional and structural adaptations of skeletal muscle to microgravity. J. Exp. Biol. 204, 3201-3208 (2001)
8. Granner, D., Pilkis, S.: The genes of hepatic glucose metabolism. J. Biol. Chem. 265, 10173-10176 (1990)
9. Greenleaf, J.E., Hutchinson, T., Shaffer-Bailey, M., Looft-Wilson, R.: Exercise thermoregulation after 6 h of chair rest, 6 degrees head-down bed-rest, and water immersion deconditioning in men. Eur. J. Appl. Physiol. Occup. Physiol. 72, 303-309 (1996)
10. Holbrook, J.J., Liljas, A., Steindel, S.J., Rossmann, M.G.: Lactate dehydrogenase. In: Boyer, P.D. (ed.) The Enzymes, 3rd edn, pp. 191-292. Academic, New York (1975)
11. Hue, L., Rider, M.H.: Role of fructose 2,6-bisphosphate in the control of glycolysis in mammalian tissues. Biochem. J. 245, 313-324 (1987)
12. Kasper, C.E., Xun, L.: Cyotplasm-to-myonucleus ratios following microgravity. J. Muscle Res. Cell. Motil. 17, 595-602 (1996)
13. Moody, S.A., Golden, C.: Developmental biology research in space: issues and directions in the era of the international space station. Dev. Biol. 228, 1-5 (2000)
14. Morey-Holton, E.R., Globus, R.K.: Hindlimb unloading rodent model: technical aspects. J. Appl. Physiol. 92, 1367-1377 (2002)
15. Ophardt, C.E.: Virtual Chembook. http://www.elmhurst.edu/%7Echm/ vchembook/. Elnhurst College. Accessed 28 Sept 2006 (2003)
16. Pilkis, S.J., El-Maghrabi, M.R., Claus, T.H.: Hormonal regulation of hepatic gluconeogenesis and glycolysis. A review of fructose-2, 6-bisphosphate and the hormonal control of levels of this gluconeogenic regulator. Annu. Rev. Biochem. 57, 755-784 (1988)
17. Saier, M.H.: Enzymes in Metabolic Pathways: A Comparative Study of Mechanism, Structure, Evolution, and Control. Harpercollins College Div, New York (1986)
18. Scheer, W.D., Lehmann, H.P., Beeler, M.F.: An improved assay for hexokinase activity in human tissue homogenates. Anal. Biochem. 91, 451-463 (1978)
19. Sharma, S.C., Richards, J.S.: Regulation of AP1 (Jun/Fos) factor expression and activation in ovarian granulose cells. Relation of JunD and Fra2 to terminal differentiation. J. Biol. Chem. 275, 33718-33728 (2000)
20. Sharma, C.S., Sarkar, S., Periyakaruppan, A., Ravichandran, P., Sadanandan, B., Ramesh, V., Thomas, R., Hall, J.C., Wilson, B.L., Ramesh, G.T.: Simulated microgravity activates apoptosis and NF-kappaB in mice testis. Mol. Cell Biochem. 313, 71-78 (2008)
21. Stein, T.P.: Space flight and oxidative stress. Nutrition 10, 867-871 (2002)
22. Stein, T.P., Margaret, S.D., Galante, A.T., Soteropolus, P., Ramirez, M., Bigbee, A., Grindeland, R.E., Wade, C.E.: Effects of hind limb muscle unloading on liver metabolism of rats. J. Nutr. Biochem. 16, 9-16 (2005)
23. Stevenson, E.J., Girest, P.G., Koncarevic, A., Kandarian, S.C.: Global analysis of gene expression patterns during disuse atrophy in rat skeletal muscle. J. Physiol. 551, 33-48 (2003)
24. Wise, K.C., Manna, S.K., Yamauchi, K., Ramesh, V., Wilson, B.L., Thomas, R.L., Sarkar, S., Kulkarni, A.D., Pellis, N.R., Ramesh, G.T.: Activation of nuclear transcription factor-kB in mouse brain induced by a simulated microgravity environment. In Vitro Cell Dev. Biol. Anim. 41, 118-23 (2005)
25. Young, C.S.J.: Effects of microgravity on cell cytoskeleton and embroygenesis. Int. J. Dev. Biol. 50, 183-191 (2006)