The antidepressant agomelatine improves memory deterioration and upregulates CREB and BDNF gene expression levels in unpredictable chronic mild stress (UCMS)-exposed mice

Drug Target Insights

Volumn 2014, Issue 8, 2014, Pages 11-21

  Gumuslu, Esen ^a   Mutlu, Oguz ^a   Sunnetci, Deniz ^a   Ulak, Guner ^a   Celikyurt, Ipek K ^a   Cine, Naci ^a   Akar, Furuzan ^a   Savli, Hakan ^a   Erden, Faruk ^a  

^a Department of Medical Genetics ^*  (Turkey)

Author keywords

Agomelatine; BDNF; CREB; Depression; Melatonin; Memory

Indexed keywords

AGOMELATINE; BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MELATONIN; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ELEVATED PLUS MAZE TEST; GENE EXPRESSION; HIPPOCAMPUS; MALE; MEMORY DISORDER; MENTAL DETERIORATION; MENTAL STRESS; MOLECULAR MECHANICS; MORRIS WATER MAZE TEST; MOUSE; NONHUMAN; NOVEL OBJECT RECOGNITION TEST; PASSIVE AVOIDANCE TEST; PROTEIN ANALYSIS; QUANTITATIVE STUDY; REAL TIME POLYMERASE CHAIN REACTION; SPATIAL LEARNING; TASK PERFORMANCE; TISSUE LEVEL; VISUAL MEMORY;

EID: 84895894644     PISSN: None     EISSN: 11773928     Source Type: Journal    
DOI: 10.4137/DTI.S13870     Document Type: Article

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