Concurrent administration of subeffective doses of scopolamine and MK- 801 produces a short-term amnesia for the elevated plus-maze in mice

Behavioural Brain Research

Volumn 91, Issue 1-2, 1998, Pages 83-89

  Hliňák, Zdeněk ^a   Krejčí, Ivan ^a  

^a Research Institute of Pharmacy and Biochemistry Prague   (Czech Republic)

Author keywords

Amnesia; Elevated plus maze; Learning; Memory; Mice; MK 801; Scopolamine

Indexed keywords

DIZOCILPINE; SCOPOLAMINE; UNCLASSIFIED DRUG; VUFB 17644;

AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COGNITION; CONTROLLED STUDY; DRUG EFFECT; DRUG RECEPTOR BINDING; LEARNING; LONG TERM POTENTIATION; MAZE TEST; MEMORY; MOUSE; NONHUMAN; PASSIVE AVOIDANCE; PRIORITY JOURNAL; SHORT TERM MEMORY; TASK PERFORMANCE;

AMNESIA; ANIMALS; DIZOCILPINE MALEATE; DRUG SYNERGISM; FEMALE; GABA ANTAGONISTS; MAZE LEARNING; MICE; MUSCARINIC ANTAGONISTS; RECEPTORS, N-METHYL-D-ASPARTATE; SCOPOLAMINE;

EID: 0032033834     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-4328(97)00107-1     Document Type: Article

References (68)

1. Aigner T.G., Mitchell S.J., Aggleton J.P., DeLong M.R., Struble R.G., Price D.L., Wenk G.L., Mishkin M. Effects of scopolamine and physostigmine on recognition memory in monkeys with ibotenic acid lesions of the nucleus basalis of Meynert. Psychopharmacology. 92:1987;292-300.
2. Albanus L. Central and peripheral effects of anticholinergic compounds. Acta Pharmacologia. 28:1970;305-326.
3. Anderson P.S., Haubrich D. Memory and learning. Ann Rev Med Chem. 16:1982;51-60.
4. Bartus R.T., Dean R.L., Pontecorvo M.J., Flicker C. The cholinergic hypothesis: A historical overview, current perspective and future directions. Ann New York Acad Sci. 444:1985;332-358.
5. Baxter M.G., Bucci D.J., Gorman L.K., Wiley R.G., Gallagher M. Selective immunotoxic lesions of basal forebrain cholinergic cells: effects on learning and memory in rats. Behav Neurosci. 109:1995;714-722.
6. Benvenga M.J., Spaulding T.C. Amnesic effect of the novel anticonvulsant MK-801. Pharmacol Biochem Behav. 30:1988;205-207.
7. Bliss T.V.P., Coliingridge G.L. A synaptic model of memory: long-term potentiation in the hippocampus. Nature (London). 361:1993;31-39.
8. Bushnell P.J. Effects of scopolamine on locomotor activity and metabolic rate in mice. Pharmacol Biochem Behav. 26:1987;195-198.
9. Butelman E.R. A novel NMDA antagonist, MK-801, impairs performance in a hippocampal-dependent spatial learning task. Pharmacol Biochem Behav. 34:1989;13-16.
10. Carlton P.L. Cholinergic mechanisms in the control of behaviour by the brain. Psychol Rev. 70:1963;19-39.
11. Castellano C., Mele A., Oliverio A. Glutamatergic-cholinergic interaction on memory consolidation in mice. Psychobiology. 24:1996;57-61.
12. Clineschmidt B.V., Williams M., Witoslawski J.J., Bunting P., Risley E.A., Totaro J.A. Restoration of shock-suppressed behavior by treatment with (+)-5-methyl-10,11-dihydro-5H-dibenzo [a,d]cyclohepten-5,10-imine (MK-801), a substance with potent anticonvulsant, central sympathomimetic and apparent anxiolytic properties. Drug Dev Res. 2:1982;147-163.
13. Collingridge G.L., Singer W. Excitatory amino acid receptors and synaptic plasticity. Trends Pharmacol Sci. 11:1990;290-296.
14. Danysz W., Wroblewski J.T., Costa E. Learning impairment in rats by N-methyl-D-aspartate receptor antagonists. Neuropharmacology. 27:1988;653-656.
15. Dunn R.W., Corbett R., Fielding S. Effects of 5-HT1A receptor agonists and NMDA receptor antagonists in the social interaction test and the elevated plus maze. Eur J Pharmacol. 169:1989;1-10.
16. Falter U, Gower A, Gober J. Anxiogenic effects of scopolamine observed in rats in the elevated plus-maze. In: File SE, Briley M, editors. New Concept in Anxiety. London: Macmillan Press, 1991:332-37.
17. Fibiger H.C. Cholinergic mechanisms in learning, memory and dementia: a review of recent evidence. Trends Neurosci. 14:1991;220-223.
18. Ford L.M., Norman A.B., Sanberg P.R. The topography of MK-801-induced locomotor patterns in rats. Physiol Behav. 46:1989;755-758.
19. Hargreaves E.L., Cain D.P. Hyperactivity, hyper-reactivity, and sensorimotor deficits induced by low doses of the N-methyl-D-aspartate non-competitive channel blocker MK801. Behav Brain Res. 47:1992;23-33.
20. Hargreaves E.L., Cain D.P. MK-801-induced hyperactivity: duration of effects in rats. Pharmacol Biochem Behav. 51:1995;13-19.
21. Hirsch S.R., Das I., Garey L.J., De Belleroche J. A pivotal role for glutamate in the pathogenesis of schizophrenia and its cognitive dysfunction. Pharmacol Biochem Behav. 56:1997;797-802.
22. Hliòák Z., Krejèí I. Effects of excitatory amino acid antagonists on social recognition of male rats. Behav Pharmacol. 5:1994;239-244.
23. Hliòák Z., Vinšová J., Kasafírek E. Effect of alaptide, its analogues and oxiracetam on memory for an elevated plus-maze in mice. Eur J Pharmacol. 314:1996;1-7.
24. Hughes R.N., Blampied N.M., Stewart W.J. Scopolamine-induced changes in activity and reactions to novelty. Pharmacol Biochem Behav. 3:1975;731-734.
25. Huppert F.A., Deutsch J.A. Improvement in memory with time. J Exp Psychol. 21:1969;267-271.
26. Itoh J., Nabeshima T., Kameyama T. Utility of an elevated plus-maze for the evaluation of memory in mice: effects of nootropics, scopolamine and electroconvulsive shock. Psychopharmacology. 101:1990;27-33.
27. Itoh J., Nabeshima T., Kameyama T. Utility of an elevated plus-maze for dissociation of amnesic and behavioral effects of drugs in mice. Eur J Pharmacol. 194:1991;71-76.
28. Izquierdo I., daCunha C., Rosat R., Jerusalinsky D., Ferreira M.B., Medina J.H. Neurotransmitter receptors involved in post-training memory processing by the amygdala, medial septum and hippocampus of the rat. Behav Neural Biol. 58:1992;16-26.
29. Jerusalinsky D., Kornisiuk E., Izquierdo I. Cholinergic neurotransmission and synaptic plasticity concerning memory processing. Neurochem Res. 22:1997;507-516.
30. Kobayashi M., Ohno M., Yamamotu T., Watanabe S. Concurrent blockade of beta-adrenergic and muscarinic receptors disrupts working memory but no reference memory on rats. Physiol Behav. 58:1995;307-314.
31. Lin Y., Phillis J.W. Muscarinic agonist-mediated induction of long-term potentiation in rat cerberal cortex. Brain Res. 551:1991;342-345.
32. Lister R.G. The use of a plus-maze to measure anxiety in the mouse. Psychopharmacology. 92:1987;180-185.
33. Markran H., Segal M. Long-lasting facilitation of excitatory postsynaptic potentials in the rat hippocampus by acetylcholine. J Physiol. 427:1990;381-393.
34. Markran H., Segal M. The inositol 1,4,5-triphosphate pathways mediate cholinergic potentiation of rat hippocampal neuronal responses to NMDA. J Physiol. 447:1992;513-533.
35. Matsuoka N., Aigner T.G. Cholinergic-glutamatergic interactions in visual recognition memory of rhezus monkeys. Neuroreport. 7:1996;565-568.
36. McGaugh J.L. Drug facilitation of learning and memory. Ann Rev Pharmacol. 13:1973;229-241.
37. McMahon S.W., Blampied N.M., Hughes R.N. Aversive stimulus properties of scopolamine. Pharmacol Biochem Behav. 15:1981;389-392.
38. Miayazaki S., Imaizumi M., Onodera K. Ameliorating effects of histidine on learning deficits in an elevated plus-maze test in mice and the contribution of cholinergic neuronal systems. Meth Find Exp Clin Pharmacol. 17:1995;57-63.
39. Miayazaki S., Imaizumi M., Onodera K. Ameliorating effects of histidine on scopolamine-induced learning deficits using an elevated plus-maze test in mice. Life Sci. 56:1995;1563-1570.
40. Misztal M., Danysz W. Comparison of glutamate antagonists in continusous multiple-trial and single-trial dark avoidance. Behav Pharmacol. 6:1995;550-561.
41. Mondadori C., Borkowski J., Gentsch C. The memory-facilitating effects of the competitive NMDA-receptor antagonist CGP 37849 are steroid-sensitive, whereas its memory-impairing effects are not. Psychopharmacology. 124:1996;380-383.
42. Muir J.L. Acetylcholine, aging, and Alzheimer's disease. Pharmacol Biochem Behav. 56:1997;687-696.
43. Murray T.K., Ridley R.M., Snape M.F., Cross A.J. The effect of dizocilpine (MK-801) on spatial and visual discrimination tasks in the rat. Behav Pharmacol. 6:1995;540-549.
44. Ohno M., Watanabe S. Interactive processing between glutamatergic and cholinergic systems involved in inhibitory avoidance learning of rats. Eur J Pharmacol. 312:1996;145-147.
45. Pellow S., Chopin P., File S.E., Briley M. Validation of open:closed arms entries in an elevated plus-maze as a measure of anxiety in the rat. J Neurosci Methods. 14:1985;149-167.
46. Pitkänen M., Sirviö J., MacDonald E., Ekonsalo T., Riekkinen Sr P. The effects of D-cycloserine, a partial agonist at the glycine binding site, on spatial learning and working memory in scopolamine-treated rats. J Neural Transm. 9:1995;133-144.
47. Plotnik R., Mollenauer S., Snyder E. Fear reduction in the rat following central cholinergic blockade. J Comp Physiol Psychol. 86:1974;1074-1082.
48. Porter J.H., Wiley J.L., Balster R.L. Effects of phencyclidine-like drugs on punished behavior in rats. J Pharmacol Exp Ther. 248:1989;997-1002.
49. Rison R.A., Stanton P.K. Long-term potentiation and N-methyl-D-aspartate receptors: Foundations of memory and neurologic disease? Neurosci Biobehav Rev. 19:1995;533-552.
50. Robinson G.S., Crooks G.B., Shinkman P.G., Gallagher M. Behavioral effects of MK-801 mimic deficits associated with hippocampal damage. Psychobiology. 17:1989;156-164.
51. Rodgers R.J., Blanchard D.C., Wong L.K., Blanchard R.J. Effects of scopolamine on antipredator defense reactions in wild and laboratory rats. Pharmacol Biochem Behav. 36:1990;575-583.
52. Rodgers R.J., Cole J.C. Effects of scopolamine and its quaternary analogue in the murine elevated plus-maze test of anxiety. Behav Pharmacol. 6:1995;283-289.
53. Sanger D.J., Joly D. The effects of NMDA antagonists on punished exploration in mice. Behav Pharmacol. 2:1991;380-383.
54. Satinder K.P., Valliant P.M. Scopolamine interacts with reactions to cat and genotype emotionality in rat. Pharmacol Biochem Behav. 9:1978;421-424.
55. Shepherd J.K. Preliminary evaluation pf an elevated 'zero-maze' as a model of anxiety in laboratory rats. J Psychopharmacol. 6A(56):1993;223.
56. Smith G. Animal models of Alzheimer's disease: experimental cholinergic denervation. Brain Res Rev. 13:1988;103-118.
57. Smythe J.W., Murphy D., Bhatnagar S., Timothy C., Costall B. Muscarinic antagonists are anxiogenic in rats tested in the black-white box. Pharmacol Biochem Behav. 54:1996;57-63.
58. Smythe J.W., Murphy D., Timothy C., Hassan Gul G.A., Costall B. Cognitive dysfunctions induced by scopolamine are reduced by systemic or intra hippocampal mineralocorticoid receptor blockade. Pharmacol Biochem Behav. 56:1997;613-621.
59. Teyler T.J., Discenna P. Long-term potentiation as a candidate mnemonic device. Brain Res Rev. 7:1984;15-28.
60. Treit D., Menard J., Royan C. Anxiogenic stimuli in the elevated plus-maze. Pharmacol Biochem Behav. 44:1993;463-469.
61. Tricklebank M.D., Singh L., Ryszard J.O., Preston C., Iverson S.D. The behavioural effects of MK-801: a comparison with antagonists acting non-competitively and competitively at the NMDA receptor. Eur J Pharmacol. 167:1989;127-135.
62. Trullas R., Jackson B., Skolnick P. Anxiolytic properties of 1-aminocyclopropanecarboxylic acid, a ligand at struchnine-insensitive glycine receptors. Pharmacol Biochem Behav. 34:1989;313-316.
63. Whishaw I.Q., Auer R.N. Immediate and long-lasting effects of MK-801 on motor activity spatial navigation in a swimming pool and EEG in the rat. Psychopharmacology. 98:1989;500-507.
64. Wickelgren W.A. Trace resistance and the decay of long term memory. J Math Psychol. 9:1972;418-455.
65. Wong E.H.F., Kemp J.A., Priestly T., Knight A.R., Woodruff G.N., Iversen L.L. The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist. Proc Natl Acad Sci USA. 83:1983;7104-7108.
66. Woods JH, Koek W, France CP. J.M. Moerschbaecher. In: Meldrum BS, editor. Excitatory Amino Acid Antagonists. Oxford: Blackwell Scientific, 1990:237-64.
67. Wozniak D.F., Olney J.W., Kettinger III L., Price M., Miller J.P. Behavioral effects of MK-801 in the rat. Psychopharmacology. 101:1990;47-56.
68. Zajaczkowski W., Danysz W. Effects of D-cycloserine and aniracetam on spatial learning in rats with entorhinal cortex lesions. Pharmacol Biochem Behav. 56:1997;21-29.