Acceptability and challenges of rapid ART initiation among pregnant women in a pilot programme, Cape Town, South Africa

AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV

Volumn 26, Issue 6, 2014, Pages 736-741

  Black, Samantha ^a   Zulliger, Rose ^b   Marcus, Rebecca ^a   Mark, Daniella ^a,c   Myer, Landon ^a   Bekker, Linda Gail ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^c Paediatric AIDS Treatment for Africa   (South Africa)

Author keywords

acceptability; antiretroviral therapy; HIV AIDS; pregnancy; prevention of mother to child transmission; South Africa; treatment initiation

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

ADULT; ANTIVIRAL THERAPY; ARTICLE; CLINICAL ARTICLE; COUNSELING; FEMALE; HEALTH PROGRAM; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTERVENTION STUDY; MOTIVATION; PILOT STUDY; PREGNANT WOMAN; PRIORITY JOURNAL; RAPID INITIATION OF ANTIRETROVIRAL THERAPY IN PREGNANCY PROGRAM; SEMI STRUCTURED INTERVIEW; SOUTH AFRICA; YOUNG ADULT;

ADULT; ANTI-HIV AGENTS; CD4 LYMPHOCYTE COUNT; COUNSELING; FEMALE; HIV INFECTIONS; HUMANS; INFECTIOUS DISEASE TRANSMISSION, VERTICAL; INTERVENTION STUDIES; PATIENT ACCEPTANCE OF HEALTH CARE; PILOT PROJECTS; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; PRENATAL CARE; SOCIOECONOMIC FACTORS; SOUTH AFRICA; TIME FACTORS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84895562856     PISSN: 09540121     EISSN: 13600451     Source Type: Journal    
DOI: 10.1080/09540121.2013.855300     Document Type: Article

References (26)

1. Abrams, E. J, Myer, L., Rosenfield, A., & El-Sadr, W. M. (2007). Prevention of mother-to-child transmission services as a gateway to family-based human immunodeficiency virus care and treatment in resource-limited settings: Rationale and international experiences. American Journal of Obstetric Gynecology, 197(Suppl. 3), S101-S106. doi:10.1016/j.ajog.2007.03.068
2. Black, S., Zulliger, R. E., Myer, L., Marcus, R., Jeneker, S., Taliep, R., ⋯ Bekker, L. G. (2013). Safety, feasibility and efficacy of a rapid ART initiation in pregnancy pilot programme, in Cape Town, South Africa. South African Medical Journal, 103(8), 557-562.
3. Chivonivoni, C., Ehlers, V. J., & Roos, J. H. (2008). Mother's attitudes towards using services preventing mother-tochild transmission of HIV in Zimbabwe: an interview survey. International Journal of Nursing Studies, 45(11). doi:10.1016/j.ijnurstu.2008.04.002
4. Chen, J. Y., Ogwu, A. C., Svab, P., Lockman, S., Moffat, H. J., Goalathe, T., ⋯ Shapiro, R. L. (2010). Antiretroviral treatment initiation among HIV-infected pregnant women with low CD4+ cell counts in Gaborone, Botswana. Journal of Acquired Immune Deficiency Syndromes, 54, 102-106. doi:10.1097/QAI.0b013e3181d61c2e
5. Delva, W., Draper, B., & Temmerman, M. (2006). Implementation of single-dose nevirapine for prevention of MTCT of HIV-Lessons from Cape Town. South African Medical Journal, 96, 706-710.
6. Department of Health of the Western Cape [South Africa]. (2008). Policy and guidelines for the prevention of mother to child transmission of HIV. Cape Town: Provincial Government of the Western Cape.
7. European Collaborative Study. (2007). Time to undetectable viral load after highly active antiretroviral therapy initiation among HIV-infected pregnant women. Clinical Infectious Diseases, 44, 1647-1656. doi:10.1086/518284
8. Ferguson, L., Grant, A., Watson-Jones, D., Kahawita, T., Ong'ech, J., & Ross, D. (2012). Linking women who test HIV-positive in pregnancy-related services to longterm HIV care and treatment services: a systematic review. Tropical Medicine and International Health, 17, 564-580. doi:10.1111/j.1365- 3156.2012.02958.x
9. Fitzgerald, F. C., Bekker, L. G., Kaplan, R., Myer, L., Lawn, S. D., & Wood, R. (2010). Mother-to-child transmission of HIV in a community-based antiretroviral clinic in South Africa. South African Medical Journal, 100, 827-831. doi:10.1111/j.1365-3156.2010.02538.x
10. Garcia, P. M., Kalish, L. A., Pitt, J., Minkoff, H., Quinn, T. C., Burchett, S. K., ⋯ Lew, J. F. (1999). Maternal levels of plasma human immunodeficiency virus type 1 RNA and the risk of perinatal transmission. The New England Journal of Medicine, 341, 394-402. doi:10.1056/NEJM1999080534 10602
11. Green, J., & Thorogood, N. (2009). Qualitative methods for health research (2nd ed.). London: Sage.
12. Grimes, R., & Grimes, D. (2010). Readiness: The state of the science (or the lack thereof). Current HIV/AIDS Reports, 7, 245-252. doi:10.1007/s11904-010-0056-2
13. Joint United Nations Programme on HIV/AIDS (UNAIDS). (2011). Countdown to zero: global plan for the elimination of new HIV infections among children by 2015 and keeping their mothers alive, 2011-2015. Retrieved from http://www.unaids.org/en/media/unaids/contentassets/docu ments/ unaidspublication/2011/20110609-JC2137-Global-Plan-elimination-HIv-Children-en. pdf
14. Kaplan, R., Orrell, C., Zwane, E., Bekker, L.G., & Wood, R. (2008). Loss to follow-up and mortality amongst pregnant women referred to a community clinic for antiretroviral treatment. AIDS, 22, 1679-1681. doi:10.1097/QAD.0b013 e32830ebcee
15. Katzenstein, D., Mbisvo, M., Zijenah, L., Glittens, T., Munjoma, M., Hill, D., ⋯ Maldonado, Y. (1999). Serum level of maternal human immunodeficiency virus RNA, infant mortality, and vertical transmission of HIV in Zimbabwe. Journal Infectious Diseases, 179, 1382-1387. doi:10.1086/314767
16. Murray, L. K., Semrau, K., McCurley, E., Thea, D. M., Scott, N., Mwiya, M., ⋯ Bolton P. (2009). Barriers to acceptance and adherence of antiretroviral therapy in urban Zambian women: A qualitative study. AIDS Care, 21, 78-86. doi:10.1080/09540120802032643
17. Myer, L., Zulliger, R., Black, S., Pienaar, D., & Bekker, L. G. (2012). Pilot programme for the rapid initiation of antiretroviral therapy in pregnancy in Cape Town, South Africa. AIDS Care, 24, 986-992. doi:10.1080/09540121.2012. 668173
18. National Department of Health [South Africa]. (2010). Clinical guidelines for the management of HIV and AIDS in adults and adolescents. Pretoria: Author.
19. National Department of Health [South Africa]. (2013). The South African antiretroviral treatment guidelines 2013. PMTCT guidelines. Retrieved from http://www.hst.org.za/publications/pmtct-guidelines-2013
20. Peltzer, K., Skinner, D., Mfecane, S., Shisana, O., Nqeketo, A., & Mosala, T. (2005). Factors influencing the utilization of prevention of mother-to-child transmission (PMTCT) services by pregnant women in the Eastern Cape, South Africa. Health SA Gesondheid, 10(1), 26-40. doi:10.4102/hsag.v10i1. 186
21. Posse, M., Meheus, F., van Asten, H., van der Ven, A., & Baltussen, R. (2008). Barriers to access to antiretroviral treatment in developing countries: A review. Tropical Medicine and International Health, 13, 904-913. doi:10.1111/j.1365-3156.2008.02091.x
22. Stinson, K., Boulle, A., Coetzee, D., Abrams, E. J., & Myer, L. (2010). Initiation of highly active antiretroviral therapy among pregnant women in Cape Town, South Africa. Tropical Medicine and International Health, 15, 825-832. doi:10.1111/j.1365-3156.2010.02538.x
23. Stinson, K., & Myer, L. (2012). Barriers to initiating antiretroviral therapy during pregnancy: A qualitative study of women attending services in Cape Town, South Africa. African Journal of AIDS Research, 11(1), 65-73. doi:10.2989/16085906.2012.671263
24. Taha, T., Kumwenda, J., Cole, S. R., Hoover, D. R., Kafulafula, G., Fowla, G., ⋯ Mofenson, L. (2009). Postnatal HIV-1 transmission after cessation of infant extended anti-retroviral prophlaxis and effect of maternal highly active antiretroviral therapy. Journal of Infectious Diseases, 200, 1490-1497. doi:10.1086/644598
25. UNAIDS. (2012). Global report: UNAIDS report on the global AIDS epidemic. Retrieved from http://www.unaids.org/en/media/unaids/contentassets/documents/ epidemiology/2012/gr2012/20121120-UNAIDS-Global-Report-2012- en.pdf
26. WHO. (2013). Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection: Recommendations for a public health approach. Retrieved from http://apps.who.int/iris/bitstream/10665/85321/1/ 9789241505727-eng.pdf