Dimethylarginine dimethylaminohydrolase II overexpression attenuates LPS-mediated lung leak in acute lung injury

American Journal of Respiratory Cell and Molecular Biology

Volumn 50, Issue 3, 2014, Pages 614-625

  Aggarwal, Saurabh ^a   Gross, Christine M ^a   Kumar, Sanjiv ^a   Dimitropoulou, Christiana ^a   Sharma, Shruti ^a   Gorshkov, Boris A ^a   Sridhar, Supriya ^a   Lu, Qing ^a   Bogatcheva, Natalia V ^a   Jezierska Drutel, Agnieszka J ^a   Lucas, Rudolf ^a   Verin, Alexander D ^a   Catravas, John D ^a   Black, Stephen M ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Acute lung injury; Asymmetric dimethylarginine; Dimethylarginine dimethylaminohydrolase II; Gene delivery; Nitrative stress

Indexed keywords

BALF PROTEIN; DIMETHYLARGININASE; DIMETHYLARGININASE 2; LIPOPOLYSACCHARIDE; N(G),N(G) DIMETHYLARGININE; PEROXYNITRITE; PROTEIN; SUPEROXIDE; UNCLASSIFIED DRUG;

ACUTE LUNG INJURY; ADJUVANT THERAPY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL PERMEABILITY; CAPILLARY LEAK SYNDROME; CONTROLLED STUDY; ENZYME ACTIVITY; EXPRESSION VECTOR; GENE TARGETING; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG BLOOD VESSEL; LUNG CAPILLARY; LUNG FUNCTION; LUNG LEAK; MALE; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NITRATION; NITRATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PROTEIN LOCALIZATION;

ACUTE LUNG INJURY; AMIDOHYDROLASES; ANIMALS; ARGININE; BRONCHOALVEOLAR LAVAGE FLUID; CAPILLARY PERMEABILITY; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; GENETIC THERAPY; HUMANS; LIPOPOLYSACCHARIDES; LUNG; MALE; MICE; MICE, INBRED C57BL; MICROVESSELS; OXIDATIVE STRESS; PEROXYNITROUS ACID; PULMONARY EDEMA; SUPEROXIDES; TIME FACTORS; TRANSFECTION; UP-REGULATION;

EID: 84895519654     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2013-0193OC     Document Type: Article

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