Development and validation of a chemostat gut model to study both planktonic and biofilm modes of growth of Clostridium difficile and human microbiota

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Crowther, Grace S ^a   Chilton, Caroline H ^a   Todhunter, Sharie L ^a   Nicholson, Scott ^d   Freeman, Jane ^b   Baines, Simon D ^c   Wilcox, Mark H ^a,b  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b LEEDS TEACHING HOSPITALS NHS TRUST   (United Kingdom)

^c UNIVERSITY OF HERTFORDSHIRE   (United Kingdom)

^d UNIVERSITY OF THE WEST OF SCOTLAND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIUM COLONY; BIOFILM; BIOLOGICAL MODEL; BIOMASS; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM DIFFICILE INFECTION; COLONY FORMING UNIT; CONCEPTUAL FRAMEWORK; CONTROLLED STUDY; EMULSION; FECES ANALYSIS; GASTROINTESTINAL TRACT; IN VITRO STUDY; IN VIVO STUDY; LONGITUDINAL STUDY; MICROBIAL COMMUNITY; NONHUMAN; PHYSICAL PARAMETERS; PLANKTONIC MODE; SAMPLING; SIMULATION; VALIDATION STUDY; CULTURE MEDIUM; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; HUMAN; ISOLATION AND PURIFICATION; MICROBIOLOGY; MICROFLORA; PEPTOCLOSTRIDIUM DIFFICILE; PHARMACOLOGY; PLANKTON; REPRODUCIBILITY;

CULTURE MEDIUM;

BIOFILMS; CLOSTRIDIUM DIFFICILE; CULTURE MEDIA; GASTROINTESTINAL TRACT; HUMANS; MICROBIOTA; MODELS, BIOLOGICAL; PLANKTON; REPRODUCIBILITY OF RESULTS;

EID: 84895511600     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088396     Document Type: Article

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