-
1
-
-
17644373442
-
Redox regulation of cell-cycle re-entry: cyclin D1 as a primary target for the mitogenic effects of reactive oxygen and nitrogen species
-
Burch P.M., Heintz N.H. Redox regulation of cell-cycle re-entry: cyclin D1 as a primary target for the mitogenic effects of reactive oxygen and nitrogen species. Antioxid. Redox Signal. 2005, 7(5-6):741-751.
-
(2005)
Antioxid. Redox Signal.
, vol.7
, Issue.5-6
, pp. 741-751
-
-
Burch, P.M.1
Heintz, N.H.2
-
2
-
-
70349799010
-
The cell cycle is a redox cycle: linking phase-specific targets to cell fate
-
Burhans W.C., Heintz N.H. The cell cycle is a redox cycle: linking phase-specific targets to cell fate. Free Radic. Biol. Med. 2009, 47(9):1282-1293.
-
(2009)
Free Radic. Biol. Med.
, vol.47
, Issue.9
, pp. 1282-1293
-
-
Burhans, W.C.1
Heintz, N.H.2
-
5
-
-
0034652113
-
Thioredoxin reductase
-
Mustacich D., Powis G. Thioredoxin reductase. Biochem. J. 2000, 346(Pt 1):1-8.
-
(2000)
Biochem. J.
, vol.346
, Issue.PRAT 1
, pp. 1-8
-
-
Mustacich, D.1
Powis, G.2
-
6
-
-
84881657606
-
Selenocysteine Confers Resistance to Inactivation by Oxidation in Thioredoxin Reductase: comparison of Selenium and Sulfur Enzymes
-
Snider G.W., et al. Selenocysteine Confers Resistance to Inactivation by Oxidation in Thioredoxin Reductase: comparison of Selenium and Sulfur Enzymes. Biochemistry 2013.
-
(2013)
Biochemistry
-
-
Snider, G.W.1
-
7
-
-
0035918571
-
Up-regulation of thioredoxin and thioredoxin reductase in human malignant pleural mesothelioma
-
Kahlos K., et al. Up-regulation of thioredoxin and thioredoxin reductase in human malignant pleural mesothelioma. Int. J. Cancer 2001, 95(3):198-204.
-
(2001)
Int. J. Cancer
, vol.95
, Issue.3
, pp. 198-204
-
-
Kahlos, K.1
-
8
-
-
3042689052
-
Antioxidant enzymes and redox regulating thiol proteins in malignancies of human lung
-
Kinnula V.L., Paakko P., Soini Y. Antioxidant enzymes and redox regulating thiol proteins in malignancies of human lung. FEBS Lett. 2004, 569(1-3):1-6.
-
(2004)
FEBS Lett.
, vol.569
, Issue.1-3
, pp. 1-6
-
-
Kinnula, V.L.1
Paakko, P.2
Soini, Y.3
-
9
-
-
84862645519
-
Peroxiredoxin 3 is a redox-dependent target of thiostrepton in malignant mesothelioma cells
-
Newick K., et al. Peroxiredoxin 3 is a redox-dependent target of thiostrepton in malignant mesothelioma cells. PLoS One 2012, 7(6):e39404.
-
(2012)
PLoS One
, vol.7
, Issue.6
-
-
Newick, K.1
-
10
-
-
78650187554
-
Targeting thioredoxin reductase: anticancer agents and chemopreventive compounds
-
Zeng H.H., Wang L.H. Targeting thioredoxin reductase: anticancer agents and chemopreventive compounds. Med. Chem. 2010, 6(5):286-297.
-
(2010)
Med. Chem.
, vol.6
, Issue.5
, pp. 286-297
-
-
Zeng, H.H.1
Wang, L.H.2
-
11
-
-
36749022747
-
Thioredoxin and thioredoxin reductase as redox-sensitive molecular targets for cancer therapy
-
Pennington J.D., et al. Thioredoxin and thioredoxin reductase as redox-sensitive molecular targets for cancer therapy. Curr. Pharm. Des. 2007, 13(33):3368-3377.
-
(2007)
Curr. Pharm. Des.
, vol.13
, Issue.33
, pp. 3368-3377
-
-
Pennington, J.D.1
-
12
-
-
33751178410
-
The thioredoxin system in cancer
-
Arner E.S., Holmgren A. The thioredoxin system in cancer. Semin. Cancer Biol. 2006, 16(6):420-426.
-
(2006)
Semin. Cancer Biol.
, vol.16
, Issue.6
, pp. 420-426
-
-
Arner, E.S.1
Holmgren, A.2
-
13
-
-
0032493647
-
Human placenta thioredoxin reductase. Isolation of the selenoenzyme, steady state kinetics, and inhibition by therapeutic gold compounds
-
Gromer S., et al. Human placenta thioredoxin reductase. Isolation of the selenoenzyme, steady state kinetics, and inhibition by therapeutic gold compounds. J. Biol. Chem. 1998, 273(32):20096-20101.
-
(1998)
J. Biol. Chem.
, vol.273
, Issue.32
, pp. 20096-20101
-
-
Gromer, S.1
-
14
-
-
5344266051
-
Gold complexes inhibit mitochondrial thioredoxin reductase: consequences on mitochondrial functions
-
Rigobello M.P., et al. Gold complexes inhibit mitochondrial thioredoxin reductase: consequences on mitochondrial functions. J. Inorg. Biochem. 2004, 98(10):1634-1641.
-
(2004)
J. Inorg. Biochem.
, vol.98
, Issue.10
, pp. 1634-1641
-
-
Rigobello, M.P.1
-
15
-
-
44849125526
-
Cell death by SecTRAPs: thioredoxin reductase as a prooxidant killer of cells
-
Anestal K., et al. Cell death by SecTRAPs: thioredoxin reductase as a prooxidant killer of cells. PLoS One 2008, 3(4):e1846.
-
(2008)
PLoS One
, vol.3
, Issue.4
-
-
Anestal, K.1
-
16
-
-
70449106252
-
Thioredoxin regulates cell cycle via the ERK1/2-cyclin D1 pathway
-
Mochizuki M., et al. Thioredoxin regulates cell cycle via the ERK1/2-cyclin D1 pathway. Antioxid. Redox Signal. 2009, 11(12):2957-2971.
-
(2009)
Antioxid. Redox Signal.
, vol.11
, Issue.12
, pp. 2957-2971
-
-
Mochizuki, M.1
-
17
-
-
84858279884
-
Overview of peroxiredoxins in oxidant defense and redox regulation
-
(Chapter 7)
-
Poole L.B., Hall A., Nelson K.J. Overview of peroxiredoxins in oxidant defense and redox regulation. Curr. Protoc. Toxicol. 2011, 7:9. (Chapter 7).
-
(2011)
Curr. Protoc. Toxicol.
, vol.7
, pp. 9
-
-
Poole, L.B.1
Hall, A.2
Nelson, K.J.3
-
18
-
-
20544459926
-
Proteomic detection of hydrogen peroxide-sensitive thiol proteins in Jurkat cells
-
Baty J.W., Hampton M.B., Winterbourn C.C. Proteomic detection of hydrogen peroxide-sensitive thiol proteins in Jurkat cells. Biochem. J. 2005, 389(Pt 3):785-795.
-
(2005)
Biochem. J.
, vol.389
, Issue.PART 3
, pp. 785-795
-
-
Baty, J.W.1
Hampton, M.B.2
Winterbourn, C.C.3
-
19
-
-
77956171017
-
Structural evidence that peroxiredoxin catalytic power is based on transition-state stabilization
-
Hall A., et al. Structural evidence that peroxiredoxin catalytic power is based on transition-state stabilization. J. Mol. Biol. 2010, 402(1):194-209.
-
(2010)
J. Mol. Biol.
, vol.402
, Issue.1
, pp. 194-209
-
-
Hall, A.1
-
20
-
-
84858279884
-
Overview of peroxiredoxins in oxidant defense and redox regulation
-
(Chapter 7)
-
Poole L.B., Hall A., Nelson K.J. Overview of peroxiredoxins in oxidant defense and redox regulation. Curr Protoc Toxicol 2011, 7:9. (Chapter 7).
-
(2011)
Curr Protoc Toxicol
, vol.7
, pp. 9
-
-
Poole, L.B.1
Hall, A.2
Nelson, K.J.3
-
21
-
-
64149085448
-
Typical 2-Cys peroxiredoxins--structures, mechanisms and functions
-
Hall A., Karplus P.A., Poole L.B. Typical 2-Cys peroxiredoxins--structures, mechanisms and functions. FEBS J. 2009, 276(9):2469-2477.
-
(2009)
FEBS J.
, vol.276
, Issue.9
, pp. 2469-2477
-
-
Hall, A.1
Karplus, P.A.2
Poole, L.B.3
-
22
-
-
0242416188
-
ATP-dependent reduction of cysteine-sulphinic acid by S. cerevisiae sulphiredoxin
-
Biteau B., Labarre J., Toledano M.B. ATP-dependent reduction of cysteine-sulphinic acid by S. cerevisiae sulphiredoxin. Nature 2003, 425(6961):980-984.
-
(2003)
Nature
, vol.425
, Issue.6961
, pp. 980-984
-
-
Biteau, B.1
Labarre, J.2
Toledano, M.B.3
-
23
-
-
10944237769
-
Characterization of mammalian sulfiredoxin and its reactivation of hyperoxidized peroxiredoxin through reduction of cysteine sulfinic acid in the active site to cysteine
-
Chang T.S., et al. Characterization of mammalian sulfiredoxin and its reactivation of hyperoxidized peroxiredoxin through reduction of cysteine sulfinic acid in the active site to cysteine. J. Biol. Chem. 2004, 279(49):50994-51001.
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.49
, pp. 50994-51001
-
-
Chang, T.S.1
-
24
-
-
79951643450
-
Multiple functions of peroxiredoxins: peroxidases, sensors and regulators of the intracellular messenger H(2)O(2), and protein chaperones
-
Rhee S.G., Woo H.A. Multiple functions of peroxiredoxins: peroxidases, sensors and regulators of the intracellular messenger H(2)O(2), and protein chaperones. Antioxid. Redox Signal. 2011, 15(3):781-794.
-
(2011)
Antioxid. Redox Signal.
, vol.15
, Issue.3
, pp. 781-794
-
-
Rhee, S.G.1
Woo, H.A.2
-
25
-
-
67349155642
-
The oligomeric conformation of peroxiredoxins links redox state to function
-
Barranco-Medina S., Lazaro J.J., Dietz K.J. The oligomeric conformation of peroxiredoxins links redox state to function. FEBS Lett. 2009, 583(12):1809-1816.
-
(2009)
FEBS Lett.
, vol.583
, Issue.12
, pp. 1809-1816
-
-
Barranco-Medina, S.1
Lazaro, J.J.2
Dietz, K.J.3
-
26
-
-
66649131702
-
Redox-regulated chaperones
-
Kumsta C., Jakob U. Redox-regulated chaperones. Biochemistry 2009, 48(22):4666-4676.
-
(2009)
Biochemistry
, vol.48
, Issue.22
, pp. 4666-4676
-
-
Kumsta, C.1
Jakob, U.2
-
27
-
-
34447518686
-
The system biology of thiol redox system in Escherichia coli and yeast: differential functions in oxidative stress, iron metabolism and DNA synthesis
-
Toledano M.B., et al. The system biology of thiol redox system in Escherichia coli and yeast: differential functions in oxidative stress, iron metabolism and DNA synthesis. FEBS Lett. 2007, 581(19):3598-3607.
-
(2007)
FEBS Lett.
, vol.581
, Issue.19
, pp. 3598-3607
-
-
Toledano, M.B.1
-
28
-
-
0033523113
-
Yap1 and Skn7 control two specialized oxidative stress response regulons in yeast
-
Lee J., et al. Yap1 and Skn7 control two specialized oxidative stress response regulons in yeast. J. Biol. Chem. 1999, 274(23):16040-16046.
-
(1999)
J. Biol. Chem.
, vol.274
, Issue.23
, pp. 16040-16046
-
-
Lee, J.1
-
29
-
-
63249111293
-
A major peroxiredoxin-induced activation of Yap1 transcription factor is mediated by reduction-sensitive disulfide bonds and reveals a low level of transcriptional activation
-
Tachibana T., et al. A major peroxiredoxin-induced activation of Yap1 transcription factor is mediated by reduction-sensitive disulfide bonds and reveals a low level of transcriptional activation. J. Biol. Chem. 2009, 284(7):4464-4472.
-
(2009)
J. Biol. Chem.
, vol.284
, Issue.7
, pp. 4464-4472
-
-
Tachibana, T.1
-
30
-
-
33744958179
-
Thioredoxin reductase 1 deficiency reverses tumor phenotype and tumorigenicity of lung carcinoma cells
-
Yoo M.H., et al. Thioredoxin reductase 1 deficiency reverses tumor phenotype and tumorigenicity of lung carcinoma cells. J. Biol. Chem. 2006, 281(19):13005-13008.
-
(2006)
J. Biol. Chem.
, vol.281
, Issue.19
, pp. 13005-13008
-
-
Yoo, M.H.1
-
31
-
-
39749177838
-
Targeting thioredoxin reductase 1 reduction in cancer cells inhibits self-sufficient growth and DNA replication
-
Yoo M.H., et al. Targeting thioredoxin reductase 1 reduction in cancer cells inhibits self-sufficient growth and DNA replication. PLoS One 2007, 2(10):e1112.
-
(2007)
PLoS One
, vol.2
, Issue.10
-
-
Yoo, M.H.1
-
32
-
-
33845303974
-
Oxidation state governs structural transitions in peroxiredoxin II that correlate with cell cycle arrest and recovery
-
Phalen T.J., et al. Oxidation state governs structural transitions in peroxiredoxin II that correlate with cell cycle arrest and recovery. J. Cell Biol. 2006, 175(5):779-789.
-
(2006)
J. Cell Biol.
, vol.175
, Issue.5
, pp. 779-789
-
-
Phalen, T.J.1
-
33
-
-
2542455473
-
Imaging dynamic redox changes in mammalian cells with green fluorescent protein indicators
-
Dooley C.T., et al. Imaging dynamic redox changes in mammalian cells with green fluorescent protein indicators. J. Biol. Chem. 2004, 279(21):22284-22293.
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.21
, pp. 22284-22293
-
-
Dooley, C.T.1
-
34
-
-
84871680714
-
Mitochondrial-targeted nitroxides disrupt mitochondrial architecture and inhibit expression of peroxiredoxin 3 and FOXM1 in malignant mesothelioma cells
-
Cunniff B., et al. Mitochondrial-targeted nitroxides disrupt mitochondrial architecture and inhibit expression of peroxiredoxin 3 and FOXM1 in malignant mesothelioma cells. J. Cell Physiol. 2013, 228(4):835-845.
-
(2013)
J. Cell Physiol.
, vol.228
, Issue.4
, pp. 835-845
-
-
Cunniff, B.1
-
35
-
-
84884509844
-
A direct and continuous assay for the determination of thioredoxin reductase activity in cell lysates
-
Cunniff B., et al. A direct and continuous assay for the determination of thioredoxin reductase activity in cell lysates. Anal. Biochem. 2013, 443(1):34-40.
-
(2013)
Anal. Biochem.
, vol.443
, Issue.1
, pp. 34-40
-
-
Cunniff, B.1
-
36
-
-
33750914460
-
Redox-dependent expression of cyclin D1 and cell proliferation by Nox1 in mouse lung epithelial cells
-
Ranjan P., et al. Redox-dependent expression of cyclin D1 and cell proliferation by Nox1 in mouse lung epithelial cells. Antioxid. Redox Signal. 2006, 8(9-10):1447-1459.
-
(2006)
Antioxid. Redox Signal.
, vol.8
, Issue.9-10
, pp. 1447-1459
-
-
Ranjan, P.1
-
37
-
-
30344455039
-
S-phase arrest by reactive nitrogen species is bypassed by okadaic acid, an inhibitor of protein phosphatases PP1/PP2A
-
Ranjan P., Heintz N.H. S-phase arrest by reactive nitrogen species is bypassed by okadaic acid, an inhibitor of protein phosphatases PP1/PP2A. Free Radic. Biol. Med. 2006, 40(2):247-259.
-
(2006)
Free Radic. Biol. Med.
, vol.40
, Issue.2
, pp. 247-259
-
-
Ranjan, P.1
Heintz, N.H.2
-
38
-
-
80052526211
-
Proteomic profiling of acrolein adducts in human lung epithelial cells
-
Spiess P.C., et al. Proteomic profiling of acrolein adducts in human lung epithelial cells. J. Proteomics 2011, 74(11):2380-2394.
-
(2011)
J. Proteomics
, vol.74
, Issue.11
, pp. 2380-2394
-
-
Spiess, P.C.1
-
39
-
-
0036829088
-
Gene expression after treatment with hydrogen peroxide, menadione, or t-butyl hydroperoxide in breast cancer cells
-
Chuang Y.Y., et al. Gene expression after treatment with hydrogen peroxide, menadione, or t-butyl hydroperoxide in breast cancer cells. Cancer Res. 2002, 62(21):6246-6254.
-
(2002)
Cancer Res.
, vol.62
, Issue.21
, pp. 6246-6254
-
-
Chuang, Y.Y.1
-
40
-
-
78650173771
-
Menadione triggers cell death through ROS-dependent mechanisms involving PARP activation without requiring apoptosis
-
Loor G., et al. Menadione triggers cell death through ROS-dependent mechanisms involving PARP activation without requiring apoptosis. Free Radic. Biol. Med. 2010, 49(12):1925-1936.
-
(2010)
Free Radic. Biol. Med.
, vol.49
, Issue.12
, pp. 1925-1936
-
-
Loor, G.1
-
41
-
-
79959345933
-
Differing views of the role of selenium in thioredoxin reductase
-
Hondal R.J., Ruggles E.L. Differing views of the role of selenium in thioredoxin reductase. Amino Acids 2011, 41(1):73-89.
-
(2011)
Amino Acids
, vol.41
, Issue.1
, pp. 73-89
-
-
Hondal, R.J.1
Ruggles, E.L.2
-
42
-
-
3042602196
-
Mitochondrial thioredoxin system: effects of TrxR2 overexpression on redox balance, cell growth, and apoptosis
-
Patenaude A., Ven Murthy M.R., Mirault M.E. Mitochondrial thioredoxin system: effects of TrxR2 overexpression on redox balance, cell growth, and apoptosis. J. Biol. Chem. 2004, 279(26):27302-27314.
-
(2004)
J. Biol. Chem.
, vol.279
, Issue.26
, pp. 27302-27314
-
-
Patenaude, A.1
Ven Murthy, M.R.2
Mirault, M.E.3
-
43
-
-
67649279837
-
Sulfiredoxin translocation into mitochondria plays a crucial role in reducing hyperoxidized peroxiredoxin III
-
Noh Y.H., et al. Sulfiredoxin translocation into mitochondria plays a crucial role in reducing hyperoxidized peroxiredoxin III. J. Biol. Chem. 2009, 284(13):8470-8477.
-
(2009)
J. Biol. Chem.
, vol.284
, Issue.13
, pp. 8470-8477
-
-
Noh, Y.H.1
-
44
-
-
73049115845
-
Selenoproteins that function in cancer prevention and promotion
-
Hatfield D.L., et al. Selenoproteins that function in cancer prevention and promotion. Biochim. Biophys. Acta 2009, 1790(11):1541-1545.
-
(2009)
Biochim. Biophys. Acta
, vol.1790
, Issue.11
, pp. 1541-1545
-
-
Hatfield, D.L.1
-
45
-
-
33748146888
-
Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate
-
Trachootham D., et al. Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate. Cancer Cell 2006, 10(3):241-252.
-
(2006)
Cancer Cell
, vol.10
, Issue.3
, pp. 241-252
-
-
Trachootham, D.1
-
46
-
-
78650724971
-
Targeted insertion of cysteine by decoding UGA codons with mammalian selenocysteine machinery
-
Xu X.M., et al. Targeted insertion of cysteine by decoding UGA codons with mammalian selenocysteine machinery. Proc. Natl. Acad. Sci. USA 2010, 107(50):21430-21434.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, Issue.50
, pp. 21430-21434
-
-
Xu, X.M.1
-
47
-
-
84862777700
-
Inactivation of a peroxiredoxin by hydrogen peroxide is critical for thioredoxin-mediated repair of oxidized proteins and cell survival
-
Day A.M., et al. Inactivation of a peroxiredoxin by hydrogen peroxide is critical for thioredoxin-mediated repair of oxidized proteins and cell survival. Mol. Cell 2012, 45(3):398-408.
-
(2012)
Mol. Cell
, vol.45
, Issue.3
, pp. 398-408
-
-
Day, A.M.1
-
48
-
-
79959345933
-
Differing views of the role of selenium in thioredoxin reductase
-
Hondal R.J., Ruggles E.L. Differing views of the role of selenium in thioredoxin reductase. Amino Acids 2010, 41(1):73-89.
-
(2010)
Amino Acids
, vol.41
, Issue.1
, pp. 73-89
-
-
Hondal, R.J.1
Ruggles, E.L.2
-
49
-
-
0034674566
-
Essential role of selenium in the catalytic activities of mammalian thioredoxin reductase revealed by characterization of recombinant enzymes with selenocysteine mutations
-
Zhong L., Holmgren A. Essential role of selenium in the catalytic activities of mammalian thioredoxin reductase revealed by characterization of recombinant enzymes with selenocysteine mutations. J. Biol. Chem. 2000, 275(24):18121-18128.
-
(2000)
J. Biol. Chem.
, vol.275
, Issue.24
, pp. 18121-18128
-
-
Zhong, L.1
Holmgren, A.2
-
50
-
-
77957315403
-
Redox compartmentalization and cellular stress
-
Jones D.P., Go Y.M. Redox compartmentalization and cellular stress. Diabetes Obes. Metab. 2010, 12(Suppl. 2):S116-S125.
-
(2010)
Diabetes Obes. Metab.
, vol.12
, Issue.SUPPL. 2
-
-
Jones, D.P.1
Go, Y.M.2
-
51
-
-
79951682393
-
Substrate and inhibitor specificities differ between human cytosolic and mitochondrial thioredoxin reductases: implications for development of specific inhibitors
-
Rackham O., et al. Substrate and inhibitor specificities differ between human cytosolic and mitochondrial thioredoxin reductases: implications for development of specific inhibitors. Free Radic. Biol. Med. 2011, 50(6):689-699.
-
(2011)
Free Radic. Biol. Med.
, vol.50
, Issue.6
, pp. 689-699
-
-
Rackham, O.1
|