Involvement of caspase 8 and c-FLIPL in the proangiogenic effects of the tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)

FEBS Journal

Volumn 281, Issue 5, 2014, Pages 1505-1513

  Cantarella, Giuseppina ^a   Di Benedetto, Giulia ^a   Ribatti, Domenico ^b   Saccani Jotti, Gloria ^c   Bernardini, Renato ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b UNIVERSITY OF BARI MEDICAL SCHOOL   (Italy)

^c UNIVERSITY OF PARMA   (Italy)

Author keywords

cell migration; chorioallantoic membrane; endothelial cells; proliferation; signal transduction

Indexed keywords

CASPASE 8; FLICE INHIBITORY PROTEIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; VASCULOTROPIN;

ANGIOGENESIS; APOPTOSIS; ARTICLE; CELL ASSAY; CELL MIGRATION; CELL MOTILITY; CHICK EMBRYO; CHORIOALLANTOIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; UMBILICAL VEIN ENDOTHELIAL CELL; WOUND HEALING;

CELL MIGRATION; CHORIOALLANTOIC MEMBRANE; ENDOTHELIAL CELLS; PROLIFERATION; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CASPASE 8; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; CHICK EMBRYO; CHORIOALLANTOIC MEMBRANE; ENZYME ACTIVATION; GENE KNOCKDOWN TECHNIQUES; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; NEOVASCULARIZATION, PHYSIOLOGIC; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; RNA, SMALL INTERFERING; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 84895500549     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.12720     Document Type: Article

References (32)

1. Baker SJ, &, Reddy EP, (1996) Transducers of life and death: TNF receptor superfamily and associated proteins. Oncogene 12, 1-9.
2. Pitti RM, Marsters SA, Ruppert S, Donahue CJ, Moore A, &, Ashkenazi A, (1996) Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J Biol Chem 271, 12687-12690.
3. Pan G, O'Rourke K, Chinnaiyan AM, Gentz R, Ebner R, Ni J, &, Dixit VM, (1997) The receptor for the cytotoxic ligand TRAIL. Science 276, 111-113.
4. Walczak H, Degli-Esposti MA, Johnson RS, Smolak PJ, Waugh JY, Boiani N, Timour MS, Gerhart MJ, Schooley KA, Smith CA, et al,. (1997) TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL. EMBO J 16, 5386-5397.
5. LeBlanc HN, &, Ashkenazi A, (2003) Apo2L/TRAIL and its death and decoy receptors. Cell Death Differ 10, 66-75.
6. Almasan A, &, Ashkenazi A, (2003) Apo2L/TRAIL: apoptosis signaling, biology, and potential for cancer therapy. Cytokine Growth Factor Rev 14, 337-348.
7. Zhang XD, Nguyen T, Thomas WD, Sanders JE, &, Hersey P, (2000) Mechanisms of resistance of normal cells to TRAIL induced apoptosis vary between different cell types. FEBS Lett 482, 193-199.
8. Cantarella G, Uberti D, Carsana T, Lombardo G, Bernardini R, &, Memo M, (2003) Neutralization of TRAIL death pathway protects human neuronal cell line from beta-amyloid toxicity. Cell Death Differ 10, 134-141.
9. Secchiero P, Gonelli A, Carnevale E, Milani D, Pandolfi A, Zella D, &, Zauli G, (2003) TRAIL promotes the survival and proliferation of primary human vascular endothelial cells by activating the Akt and ERK pathways. Circulation 107, 2250-2256.
10. Crowder RN, &, El-Deiry WS, (2012) Caspase-8 regulation of trail-mediated cell death. Exp Oncol 34, 160-164.
11. Sprick MR, Weigand MA, Rieser E, Rauch CT, Juo P, Blenis J, Krammer PH, &, Walczak H, (2000) FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2. Immunity 12, 599-609.
12. Kang TB, Ben-Moshe T, Varfolomeev EE, Pewzner-Jung Y, Yogev N, Jurewicz A, Waisman A, Brenner O, Haffner R, Gustafsson E, et al,. (2004) Caspase-8 serves both apoptotic and nonapoptotic roles. J Immunol 173, 2976-2984.
13. Kovalenko A, Kim JC, Kang TB, Rajput A, Bogdanov K, Dittrich-Breiholz O, Kracht M, Brenner O, &, Wallach D, (2009) Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease. J Exp Med 206, 2161-2177.
14. Tschopp J, Irmler M, &, Thome M, (1998) Inhibition of fas death signals by FLIPs. Curr Opin Immunol 10, 552-558.
15. Micheau O, Thome M, Schneider P, Holler N, Tschopp J, Nicholson DW, Briand C, &, Grütter MG, (2002) The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex. J Biol Chem 277, 45162-45171.
16. He MX, &, He WY, (2013) A role for c-FLIPL in the regulation of apoptosis, autophagy, and necroptosis in T lymphocytes. Cell Death Differ 20, 188-197.
17. Kaiser WJ, Upton JW, Long AB, Livingston-Rosanoff D, Daley LP, Hakem R, Caspary T, &, Mocarsky ES, (2011) RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature 471, 368-372.
18. Gochuico BR, Zhang J, Ma BY, Marshak-Rothstein A, &, Fine A, (2000) TRAIL expression in vascular smooth muscle. Am J Physiol Lung Cell Mol Physiol 278, L1045-L1050.
19. Cantarella G, Risuglia N, Dell'eva R, Lempereur L, Albini A, Pennisi G, Scoto GM, Noonan DN, &, Bernardini R, (2006) TRAIL inhibits angiogenesis stimulated by VEGF expression in human glioblastoma cells. Br J Cancer 94, 1428-1435.
20. Alladina SJ, Song JH, Davidge ST, Hao C, &, Easton AS, (2005) TRAIL-induced apoptosis in human vascular endothelium is regulated by phosphatidylinositol 3-kinase/Akt through the short form of cellular FLIP and Bcl-2. J Vasc Res 42, 337-347.
21. Ferrara N, Gerber HP, &, LeCouter J, (2003) The biology of VEGF and its receptors. Nat Med 9, 669-676.
22. Bussolino F, Mantovani A, &, Persico G, (1997) Molecular mechanisms of blood vessel formation. Trends Biochem Sci 22, 251-256.
23. Risau W, (1997) Mechanisms of angiogenesis. Nature 386, 671-674.
24. Lamkanfi M, Festjens N, Declercq W, Vanden Berghe T, &, Vandenabeele P, (2007) Caspases in cell survival, proliferation and differentiation. Cell Death Differ 14, 44-55.
25. Kataoka T, &, Tschopp J, (2004) N-terminal fragment of c-FLIP(L) processed by caspase 8 specifically interacts with TRAF2 and induces activation of the NF-kappaB signaling pathway. Mol Cell Biol 24, 2627-2636.
26. Dohrman A, Kataoka T, Cuenin S, Russell JQ, Tschopp J, &, Budd RC, (2005) Cellular FLIP (long form) regulates CD8 + T cell activation through caspase-8-dependent NF-kappa B activation. J Immunol 174, 5270-5278.
27. Chang DW, Xing Z, Pan Y, Algeciras-Schimnich A, Barnhart BC, Yaish-Ohad S, Peter ME, &, Yang X, (2002) c-FLIP(L) is a dual function regulator for caspase-8 activation and CD95-mediated apoptosis. EMBO J 21, 3704-3714.
28. Boatright KM, Deis C, Denault JB, Sutherlin DP, &, Salvesen GS, (2004) Activation of caspases-8 and -10 by FLIP(L). Biochem J 382, 651-657.
29. Secchiero P, Gonelli A, Carnevale E, Corallini F, Rizzardi C, Zacchigna S, Melato M, &, Zauli G, (2004) Evidence for a proangiogenic activity of TNF-related apoptosis-inducing ligand. Neoplasia 6, 364-373.
30. Kober AM, Legewie S, Pforr C, Fricker N, Eils R, Krammer PH, &, Lavrik IN, (2011) Caspase-8 activity has an essential role in CD95/Fas-mediated MAPK activation. Cell Death Dis 2, e212.
31. Jaffe EA, Nachman RL, Becker CG, &, Minick CR, (1973) Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J Clin Invest 52, 2745-2756.
32. Ribatti D, Nico B, Vacca A, &, Presta M, (2006) The gelatin sponge-chorioallantoic membrane assay. Nat Protoc 1, 85-91.