메뉴 건너뛰기




Volumn 22, Issue 3, 2014, Pages 623-633

Kinetics of tumor destruction by chimeric antigen receptor-modified T cells

Author keywords

[No Author keywords available]

Indexed keywords

CHIMERIC ANTIGEN RECEPTOR; MUCIN 1; PROSTATE STEM CELL ANTIGEN; T LYMPHOCYTE RECEPTOR; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

EID: 84895500137     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2013.262     Document Type: Article
Times cited : (97)

References (38)
  • 1
    • 80051720194 scopus 로고    scopus 로고
    • Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
    • Porter, DL, Levine, BL, Kalos, M, Bagg, A and June, CH (2011). Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. N Engl J Med 365: 725-733.
    • (2011) N Engl J Med , vol.365 , pp. 725-733
    • Porter, D.L.1    Levine, B.L.2    Kalos, M.3    Bagg, A.4    June, C.H.5
  • 2
    • 84863337890 scopus 로고    scopus 로고
    • B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells
    • Kochenderfer, JN, Dudley, ME, Feldman, SA, Wilson, WH, Spaner, DE, Maric, I et al. (2012). B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells. Blood 119: 2709-2720.
    • (2012) Blood , vol.119 , pp. 2709-2720
    • Kochenderfer, J.N.1    Dudley, M.E.2    Feldman, S.A.3    Wilson, W.H.4    Spaner, D.E.5    Maric, I.6
  • 3
    • 55549145071 scopus 로고    scopus 로고
    • Virusspecific T cells engineered to coexpress tumor-specific receptors: Persistence and antitumor activity in individuals with neuroblastoma
    • Pule, MA, Savoldo, B, Myers, GD, Rossig, C, Russell, HV, Dotti, G et al. (2008). Virusspecific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma. Nat Med 14: 1264-1270.
    • (2008) Nat Med , vol.14 , pp. 1264-1270
    • Pule, M.A.1    Savoldo, B.2    Myers, G.D.3    Rossig, C.4    Russell, H.V.5    Dotti, G.6
  • 4
    • 50549096284 scopus 로고    scopus 로고
    • Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells
    • Till, BG, Jensen, MC, Wang, J, Chen, EY, Wood, BL, Greisman, HA et al. (2008). Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells. Blood 112: 2261-2271.
    • (2008) Blood , vol.112 , pp. 2261-2271
    • Till, B.G.1    Jensen, M.C.2    Wang, J.3    Chen, E.Y.4    Wood, B.L.5    Greisman, H.A.6
  • 5
    • 77955510549 scopus 로고    scopus 로고
    • Antitransgene rejection responses contribute to attenuated persistence of adoptively transferred CD20/CD19-specific chimeric antigen receptor redirected T cells in humans
    • Jensen, MC, Popplewell, L, Cooper, LJ, DiGiusto, D, Kalos, M, Ostberg, JR et al. (2010). Antitransgene rejection responses contribute to attenuated persistence of adoptively transferred CD20/CD19-specific chimeric antigen receptor redirected T cells in humans. Biol Blood Marrow Transplant 16: 1245-1256.
    • (2010) Biol Blood Marrow Transplant , vol.16 , pp. 1245-1256
    • Jensen, M.C.1    Popplewell, L.2    Cooper, L.J.3    Digiusto, D.4    Kalos, M.5    Ostberg, J.R.6
  • 6
    • 84876005284 scopus 로고    scopus 로고
    • CD19- targeted T cells rapidly induce molecular remissions in adults with chemotherapyrefractory acute lymphoblastic leukemia
    • Brentjens, RJ, Davila, ML, Riviere, I, Park, J, Wang, X, Cowell, LG et al. (2013). CD19- targeted T cells rapidly induce molecular remissions in adults with chemotherapyrefractory acute lymphoblastic leukemia. Sci Transl Med 5: 177ra38.
    • (2013) Sci Transl Med , vol.5
    • Brentjens, R.J.1    Davila, M.L.2    Riviere, I.3    Park, J.4    Wang, X.5    Cowell, L.G.6
  • 7
    • 0030000146 scopus 로고    scopus 로고
    • Inverse relationship of melanocyte differentiation antigen expression in melanoma tissues and CD8+ cytotoxic-T-cell responses: Evidence for immunoselection of antigen-loss variants in vivo
    • Jäger, E, Ringhoffer, M, Karbach, J, Arand, M, Oesch, F and Knuth, A (1996). Inverse relationship of melanocyte differentiation antigen expression in melanoma tissues and CD8+ cytotoxic-T-cell responses: evidence for immunoselection of antigen-loss variants in vivo. Int J Cancer 66: 470-476.
    • (1996) Int J Cancer , vol.66 , pp. 470-476
    • Jäger, E.1    Ringhoffer, M.2    Karbach, J.3    Arand, M.4    Oesch, F.5    Knuth, A.6
  • 8
    • 0032838613 scopus 로고    scopus 로고
    • Immune selection after antigen-specific immunotherapy of melanoma
    • Riker, A, Cormier, J, Panelli, M, Kammula, U, Wang, E, Abati, A et al. (1999). Immune selection after antigen-specific immunotherapy of melanoma. Surgery 126: 112-120.
    • (1999) Surgery , vol.126 , pp. 112-120
    • Riker, A.1    Cormier, J.2    Panelli, M.3    Kammula, U.4    Wang, E.5    Abati, A.6
  • 10
    • 0346251199 scopus 로고    scopus 로고
    • MUC1 and MUC2 expression in pancreatic ductal carcinoma obtained by fine-needle aspiration
    • Chhieng, DC, Benson, E, Eltoum, I, Eloubeidi, MA, Jhala, N, Jhala, D et al. (2003). MUC1 and MUC2 expression in pancreatic ductal carcinoma obtained by fine-needle aspiration. Cancer 99: 365-371.
    • (2003) Cancer , vol.99 , pp. 365-371
    • Chhieng, D.C.1    Benson, E.2    Eltoum, I.3    Eloubeidi, M.A.4    Jhala, N.5    Jhala, D.6
  • 11
    • 3042845879 scopus 로고    scopus 로고
    • Differential expression of MUC1, MUC2, and MUC5AC in carcinomas of various sites: An immunohistochemical study
    • Lau, SK, Weiss, LM and Chu, PG (2004). Differential expression of MUC1, MUC2, and MUC5AC in carcinomas of various sites: an immunohistochemical study. Am J Clin Pathol 122: 61-69.
    • (2004) Am J Clin Pathol , vol.122 , pp. 61-69
    • Lau, S.K.1    Weiss, L.M.2    Chu, P.G.3
  • 12
    • 23044451727 scopus 로고    scopus 로고
    • Prostate stem cell antigen is a putative target for immunotherapy in pancreatic cancer
    • Wente, MN, Jain, A, Kono, E, Berberat, PO, Giese, T, Reber, HA et al. (2005). Prostate stem cell antigen is a putative target for immunotherapy in pancreatic cancer. Pancreas 31: 119-125.
    • (2005) Pancreas , vol.31 , pp. 119-125
    • Wente, M.N.1    Jain, A.2    Kono, E.3    Berberat, P.O.4    Giese, T.5    Reber, H.A.6
  • 13
    • 77956840374 scopus 로고    scopus 로고
    • Synergistic and persistent effect of T-cell immunotherapy with anti-CD19 or anti-CD38 chimeric receptor in conjunction with rituximab on B-cell non-Hodgkin lymphoma
    • Mihara, K, Yanagihara, K, Takigahira, M, Kitanaka, A, Imai, C, Bhattacharyya, J et al. (2010). Synergistic and persistent effect of T-cell immunotherapy with anti-CD19 or anti-CD38 chimeric receptor in conjunction with rituximab on B-cell non-Hodgkin lymphoma. Br J Haematol 151: 37-46.
    • (2010) Br J Haematol , vol.151 , pp. 37-46
    • Mihara, K.1    Yanagihara, K.2    Takigahira, M.3    Kitanaka, A.4    Imai, C.5    Bhattacharyya, J.6
  • 14
    • 76249116978 scopus 로고    scopus 로고
    • Antibody-mediated B-cell depletion before adoptive immunotherapy with T cells expressing CD20-specific chimeric T-cell receptors facilitates eradication of leukemia in immunocompetent mice
    • James, SE, Orgun, NN, Tedder, TF, Shlomchik, MJ, Jensen, MC, Lin, Y et al. (2009). Antibody-mediated B-cell depletion before adoptive immunotherapy with T cells expressing CD20-specific chimeric T-cell receptors facilitates eradication of leukemia in immunocompetent mice. Blood 114: 5454-5463.
    • (2009) Blood , vol.114 , pp. 5454-5463
    • James, S.E.1    Orgun, N.N.2    Tedder, T.F.3    Shlomchik, M.J.4    Jensen, M.C.5    Lin, Y.6
  • 15
    • 79955517235 scopus 로고    scopus 로고
    • CD28 costimulation improves expansion and persistence of chimeric antigen receptormodified T cells in lymphoma patients
    • Savoldo, B, Ramos, CA, Liu, E, Mims, MP, Keating, MJ, Carrum, G et al. (2011). CD28 costimulation improves expansion and persistence of chimeric antigen receptormodified T cells in lymphoma patients. J Clin Invest 121: 1822-1826.
    • (2011) J Clin Invest , vol.121 , pp. 1822-1826
    • Savoldo, B.1    Ramos, C.A.2    Liu, E.3    Mims, M.P.4    Keating, M.J.5    Carrum, G.6
  • 16
    • 84860333968 scopus 로고    scopus 로고
    • CD20- specific adoptive immunotherapy for lymphoma using a chimeric antigen receptor with both CD28 and 4-1BB domains: Pilot clinical trial results
    • Till, BG, Jensen, MC, Wang, J, Qian, X, Gopal, AK, Maloney, DG et al. (2012). CD20- specific adoptive immunotherapy for lymphoma using a chimeric antigen receptor with both CD28 and 4-1BB domains: pilot clinical trial results. Blood 119: 3940-3950.
    • (2012) Blood , vol.119 , pp. 3940-3950
    • Till, B.G.1    Jensen, M.C.2    Wang, J.3    Qian, X.4    Gopal, A.K.5    Maloney, D.G.6
  • 17
    • 82955187824 scopus 로고    scopus 로고
    • PiggyBac-mediated cancer immunotherapy using EBV-specific cytotoxic T-cells expressing HER2-specific chimeric antigen receptor
    • Nakazawa, Y, Huye, LE, Salsman, VS, Leen, AM, Ahmed, N, Rollins, L et al. (2011). PiggyBac-mediated cancer immunotherapy using EBV-specific cytotoxic T-cells expressing HER2-specific chimeric antigen receptor. Mol Ther 19: 2133-2143.
    • (2011) Mol Ther , vol.19 , pp. 2133-2143
    • Nakazawa, Y.1    Huye, L.E.2    Salsman, V.S.3    Leen, A.M.4    Ahmed, N.5    Rollins, L.6
  • 18
    • 82955207691 scopus 로고    scopus 로고
    • Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma
    • Louis, CU, Savoldo, B, Dotti, G, Pule, M, Yvon, E, Myers, GD et al. (2011). Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma. Blood 118: 6050-6056.
    • (2011) Blood , vol.118 , pp. 6050-6056
    • Louis, C.U.1    Savoldo, B.2    Dotti, G.3    Pule, M.4    Yvon, E.5    Myers, G.D.6
  • 19
    • 80051775476 scopus 로고    scopus 로고
    • T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia
    • Kalos, M, Levine, BL, Porter, DL, Katz, S, Grupp, SA, Bagg, A et al. (2011). T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia. Sci Transl Med 3: 95ra73.
    • (2011) Sci Transl Med , vol.3
    • Kalos, M.1    Levine, B.L.2    Porter, D.L.3    Katz, S.4    Grupp, S.A.5    Bagg, A.6
  • 20
    • 84874091597 scopus 로고    scopus 로고
    • Chimeric antigen receptor T cells directed against CD19 induce durable response and transient cytokine release syndrome in relapsed, refractory CLL and ALL
    • (ASH annual meeting abstract)
    • Porter, DL, Grupp, SA, Kalos, M, Loren, AW, Lledo, L, Gilmore, J et al. (2013). Chimeric antigen receptor T cells directed against CD19 induce durable response and transient cytokine release syndrome in relapsed, refractory CLL and ALL. Blood (ASH annual meeting abstract) No.717.
    • (2013) Blood , Issue.717
    • Porter, D.L.1    Grupp, S.A.2    Kalos, M.3    Loren, A.W.4    Lledo, L.5    Gilmore, J.6
  • 21
    • 35549008976 scopus 로고    scopus 로고
    • Complete responses of relapsed lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transfer
    • Bollard, CM, Gottschalk, S, Leen, AM, Weiss, H, Straathof, KC, Carrum, G et al. (2007). Complete responses of relapsed lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transfer. Blood 110: 2838-2845.
    • (2007) Blood , vol.110 , pp. 2838-2845
    • Bollard, C.M.1    Gottschalk, S.2    Leen, A.M.3    Weiss, H.4    Straathof, K.C.5    Carrum, G.6
  • 22
    • 81255143446 scopus 로고    scopus 로고
    • Improving T-cell therapy for relapsed EBV-negative Hodgkin lymphoma by targeting upregulated MAGE-A4
    • Cruz, CR, Gerdemann, U, Leen, AM, Shafer, JA, Ku, S, Tzou, B et al. (2011). Improving T-cell therapy for relapsed EBV-negative Hodgkin lymphoma by targeting upregulated MAGE-A4. Clin Cancer Res 17: 7058-7066.
    • (2011) Clin Cancer Res , vol.17 , pp. 7058-7066
    • Cruz, C.R.1    Gerdemann, U.2    Leen, A.M.3    Shafer, J.A.4    Ku, S.5    Tzou, B.6
  • 23
    • 77956924038 scopus 로고    scopus 로고
    • Induction of a CD8+ T-cell response to the MAGE cancer testis antigen by combined treatment with azacitidine and sodium valproate in patients with acute myeloid leukemia and myelodysplasia
    • Goodyear, O, Agathanggelou, A, Novitzky-Basso, I, Siddique, S, McSkeane, T, Ryan, G et al. (2010). Induction of a CD8+ T-cell response to the MAGE cancer testis antigen by combined treatment with azacitidine and sodium valproate in patients with acute myeloid leukemia and myelodysplasia. Blood 116: 1908-1918.
    • (2010) Blood , vol.116 , pp. 1908-1918
    • Goodyear, O.1    Agathanggelou, A.2    Novitzky-Basso, I.3    Siddique, S.4    McSkeane, T.5    Ryan, G.6
  • 24
    • 0034331218 scopus 로고    scopus 로고
    • Induction of cytotoxic T-lymphocyte responses in vivo after vaccinations with peptidepulsed dendritic cells
    • Brossart, P, Wirths, S, Stuhler, G, Reichardt, VL, Kanz, L and Brugger, W (2000). Induction of cytotoxic T-lymphocyte responses in vivo after vaccinations with peptidepulsed dendritic cells. Blood 96: 3102-3108.
    • (2000) Blood , vol.96 , pp. 3102-3108
    • Brossart, P.1    Wirths, S.2    Stuhler, G.3    Reichardt, V.L.4    Kanz, L.5    Brugger, W.6
  • 25
    • 33646440024 scopus 로고    scopus 로고
    • Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: First clinical experience
    • Lamers, CH, Sleijfer, S, Vulto, AG, Kruit, WH, Kliffen, M, Debets, R et al. (2006). Treatment of metastatic renal cell carcinoma with autologous T-lymphocytes genetically retargeted against carbonic anhydrase IX: first clinical experience. J Clin Oncol 24: e20-e22.
    • (2006) J Clin Oncol , vol.24
    • Lamers, C.H.1    Sleijfer, S.2    Vulto, A.G.3    Kruit, W.H.4    Kliffen, M.5    Debets, R.6
  • 26
    • 77950475517 scopus 로고    scopus 로고
    • Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2
    • Morgan, RA, Yang, JC, Kitano, M, Dudley, ME, Laurencot, CM and Rosenberg, SA (2010). Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2. Mol Ther 18: 843-851.
    • (2010) Mol Ther , vol.18 , pp. 843-851
    • Morgan, R.A.1    Yang, J.C.2    Kitano, M.3    Dudley, M.E.4    Laurencot, C.M.5    Rosenberg, S.A.6
  • 27
    • 84872196489 scopus 로고    scopus 로고
    • Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells
    • Kloss, CC, Condomines, M, Cartellieri, M, Bachmann, M and Sadelain, M (2013). Combinatorial antigen recognition with balanced signaling promotes selective tumor eradication by engineered T cells. Nat Biotechnol 31: 71-75.
    • (2013) Nat Biotechnol , vol.31 , pp. 71-75
    • Kloss, C.C.1    Condomines, M.2    Cartellieri, M.3    Bachmann, M.4    Sadelain, M.5
  • 28
    • 84866740895 scopus 로고    scopus 로고
    • Dual targeting of ErbB2 and MUC1 in breast cancer using chimeric antigen receptors engineered to provide complementary signaling
    • Wilkie, S, van Schalkwyk, MC, Hobbs, S, Davies, DM, van der Stegen, SJ, Pereira, AC et al. (2012). Dual targeting of ErbB2 and MUC1 in breast cancer using chimeric antigen receptors engineered to provide complementary signaling. J Clin Immunol 32: 1059-1070.
    • (2012) J Clin Immunol , vol.32 , pp. 1059-1070
    • Wilkie, S.1    Van Schalkwyk, M.C.2    Hobbs, S.3    Davies, D.M.4    Van Der Stegen, S.J.5    Pereira, A.C.6
  • 30
    • 33644750264 scopus 로고    scopus 로고
    • Analysis of transgenespecific immune responses that limit the in vivo persistence of adoptively transferred HSV-TK-modified donor T cells after allogeneic hematopoietic cell transplantation
    • Berger, C, Flowers, ME, Warren, EH and Riddell, SR (2006). Analysis of transgenespecific immune responses that limit the in vivo persistence of adoptively transferred HSV-TK-modified donor T cells after allogeneic hematopoietic cell transplantation. Blood 107: 2294-2302.
    • (2006) Blood , vol.107 , pp. 2294-2302
    • Berger, C.1    Flowers, M.E.2    Warren, E.H.3    Riddell, S.R.4
  • 33
    • 13144250150 scopus 로고    scopus 로고
    • Prostate stem cell antigen: A cell surface marker overexpressed in prostate cancer
    • Reiter, RE, Gu, Z, Watabe, T, Thomas, G, Szigeti, K, Davis, E et al. (1998). Prostate stem cell antigen: a cell surface marker overexpressed in prostate cancer. Proc Natl Acad Sci USA 95: 1735-1740.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 1735-1740
    • Reiter, R.E.1    Gu, Z.2    Watabe, T.3    Thomas, G.4    Szigeti, K.5    Davis, E.6
  • 34
    • 0025874680 scopus 로고
    • Molecular cloning and analysis of the mouse homologue of the tumor-associated mucin, MUC1, reveals conservation of potential O-glycosylation sites, transmembrane, and cytoplasmic domains and a loss of minisatellite-like polymorphism
    • Spicer, AP, Parry, G, Patton, S and Gendler, SJ (1991). Molecular cloning and analysis of the mouse homologue of the tumor-associated mucin, MUC1, reveals conservation of potential O-glycosylation sites, transmembrane, and cytoplasmic domains and a loss of minisatellite-like polymorphism. J Biol Chem 266: 15099-15109.
    • (1991) J Biol Chem , vol.266 , pp. 15099-15109
    • Spicer, A.P.1    Parry, G.2    Patton, S.3    Gendler, S.J.4
  • 35
    • 76949100884 scopus 로고    scopus 로고
    • Accelerated production of antigen-specific T cells for preclinical and clinical applications using gaspermeable rapid expansion cultureware (G-Rex)
    • Vera, JF, Brenner, LJ, Gerdemann, U, Ngo, MC, Sili, U, Liu, H et al. (2010). Accelerated production of antigen-specific T cells for preclinical and clinical applications using gaspermeable rapid expansion cultureware (G-Rex). J Immunother 33: 305-315.
    • (2010) J Immunother , vol.33 , pp. 305-315
    • Vera, J.F.1    Brenner, L.J.2    Gerdemann, U.3    Ngo, M.C.4    Sili, U.5    Liu, H.6
  • 36
    • 0037742210 scopus 로고    scopus 로고
    • Discovery of novel targets for aberrant methylation in pancreatic carcinoma using high-throughput microarrays
    • Sato, N, Fukushima, N, Maitra, A, Matsubayashi, H, Yeo, CJ, Cameron, JL et al. (2003). Discovery of novel targets for aberrant methylation in pancreatic carcinoma using high-throughput microarrays. Cancer Res 63: 3735-3742.
    • (2003) Cancer Res , vol.63 , pp. 3735-3742
    • Sato, N.1    Fukushima, N.2    Maitra, A.3    Matsubayashi, H.4    Yeo, C.J.5    Cameron, J.L.6
  • 37
    • 0042941382 scopus 로고    scopus 로고
    • Contribution of the MUC1 tandem repeat and cytoplasmic tail to invasive and metastatic properties of a pancreatic cancer cell line
    • Kohlgraf, KG, Gawron, AJ, Higashi, M, Meza, JL, Burdick, MD, Kitajima, S et al. (2003). Contribution of the MUC1 tandem repeat and cytoplasmic tail to invasive and metastatic properties of a pancreatic cancer cell line. Cancer Res 63: 5011-5020.
    • (2003) Cancer Res , vol.63 , pp. 5011-5020
    • Kohlgraf, K.G.1    Gawron, A.J.2    Higashi, M.3    Meza, J.L.4    Burdick, M.D.5    Kitajima, S.6
  • 38
    • 0035421307 scopus 로고    scopus 로고
    • Murine sixtransmembrane epithelial antigen of the prostate, prostate stem cell antigen, and prostate-specific membrane antigen: Prostate-specific cell-surface antigens highly expressed in prostate cancer of transgenic adenocarcinoma mouse prostate mice
    • Yang, D, Holt, GE, Velders, MP, Kwon, ED and Kast, WM (2001). Murine sixtransmembrane epithelial antigen of the prostate, prostate stem cell antigen, and prostate-specific membrane antigen: prostate-specific cell-surface antigens highly expressed in prostate cancer of transgenic adenocarcinoma mouse prostate mice. Cancer Res 61: 5857-5860.
    • (2001) Cancer Res , vol.61 , pp. 5857-5860
    • Yang, D.1    Holt, G.E.2    Velders, M.P.3    Kwon, E.D.4    Kast, W.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.