Myeloperoxidase upregulates endothelin receptor type B expression

Journal of Molecular and Cellular Cardiology

Volumn 69, Issue , 2014, Pages 76-82

  Lau, Denise ^a   Szöcs, Katalin ^a   Klinke, Anna ^b   Rudolph, Tanja ^b   Rudolph, Volker ^b   Streichert, Thomas ^a   Blankenberg, Stefan ^a   Baldus, Stephan ^b  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b UNIVERSITY HOSPITAL OF COLOGNE   (Germany)

Author keywords

Endothelial cells; Endothelin receptor type B; Myeloperoxidase; Smooth muscle cells; Vasomodulation

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ENDOTHELIN 1; ENDOTHELIN RECEPTOR; ENDOTHELIN RECEPTOR TYPE A; ENDOTHELIN RECEPTOR TYPE B; MITOGEN ACTIVATED PROTEIN KINASE; MYELOPEROXIDASE; NITRIC OXIDE; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; MESSENGER RNA; PEROXIDASE;

ANIMAL TISSUE; ARTICLE; BIOCATALYSIS; BLOOD VESSEL TONE; CELL INTERACTION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME LOCALIZATION; ENZYME RELEASE; ENZYME REPRESSION; EX VIVO STUDY; FEMORAL ARTERY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; INFLAMMATION; LEUKOCYTE ACTIVATION; NEUTROPHIL CHEMOTAXIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SMOOTH MUSCLE FIBER; SUBENDOTHELIUM; UPREGULATION; VASOCONSTRICTION; WESTERN BLOTTING; ANIMAL; AORTA; CELL CULTURE; CYTOLOGY; DNA MICROARRAY; ENZYME IMMUNOASSAY; GENE EXPRESSION PROFILING; GENETICS; MALE; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR SMOOTH MUSCLE; WISTAR RAT;

ANIMALS; AORTA; BIOLOGICAL MARKERS; BLOTTING, WESTERN; CELLS, CULTURED; GENE EXPRESSION PROFILING; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; IMMUNOENZYME TECHNIQUES; MALE; MUSCLE, SMOOTH, VASCULAR; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PEROXIDASE; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; UP-REGULATION; VASOCONSTRICTION;

EID: 84895484831     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2013.12.007     Document Type: Article

References (42)

1. Bogaard H.J., Natarajan R., Mizuno S., Abbate A., Chang P.J., Chau V.Q., et al. Adrenergic receptor blockade reverses right heart remodeling and dysfunction in pulmonary hypertensive rats. Am J Respir Crit Care Med 2010, 182:652-660.
2. Baldus S., Heeschen C., Meinertz T., Zeiher A.M., Eiserich J.P., Münzel T., et al. Myeloperoxidase serum levels predict risk in patients with acute coronary syndromes. Circulation 2003, 108:1440-1445.
3. Brennan M.L., Hazen S.L. Emerging role of myeloperoxidase and oxidant stress markers in cardiovascular risk assessment. Curr Opin Lipidol 2003, 14:353-359.
4. Buffon A., Biasucci L.M., Liuzzo G., D'Onofrio G., Crea F., Maseri A. Widespread coronary inflammation in unstable angina. N Engl J Med 2002, 347:5-12.
5. Deby-Dupont G., Deby C., Lamy M. Neutrophil myeloperoxidase revisited: it's role in health and disease. Intensivmed Notfallmed 1999, 36:500-513.
6. Tang W.H., Wu Y., Nicholls S.J., Hazen S.L. Plasma myeloperoxidase predicts incident cardiovascular risks in stable patients undergoing medical management for coronary artery disease. Clin Chem 2011, 57:33-39.
7. Goldmann B.U., Rudolph V., Rudolph T.K., Holle A.K., Hillebrandt M., Meinertz T., et al. Neutrophil activation precedes myocardial injury in patients with acute myocardial infarction. Free Radic Biol Med 2009, 47:79-83.
8. Rudolph V., Goldmann B.U., Bös C., Rudolph T.K., Klinke A., Friedrichs K., et al. Diagnostic value of MPO plasma levels in patients admitted for suspected myocardial infarction. Int J Cardiol 2011, 153:267-271.
9. Nicholls S.J., Tang W.H., Brennan D., Brennan M.L., Mann S., Nissen S.E., et al. Risk prediction with serial myeloperoxidase monitoring in patients with acute chest pain. Clin Chem 2011, 57:1762-1770.
10. Rudolph V., Rudolph T.K., Hennings J.C., Blankenberg S., Schnabel R., Steven D., et al. Activation of polymorphonuclear neutrophils in patients with impaired left ventricular function. Free Radic Biol Med 2007, 43:1189-1196.
11. Baldus S., Eiserich J.P., Mani A., Castro L., Figueroa M., Chumley P., et al. Endothelial transcytosis of myeloperoxidase confers specificity to vascular ECM proteins as targets of tyrosine nitration. J Clin Invest 2001, 108:1759-1770.
12. Eiserich J.P., Baldus S., Brennan M.L., Ma W., Zhang C., Tousson A., et al. Myeloperoxidase, a leukocyte-derived vascular NO oxidase. Science 2002, 296:2391-2394.
13. Klinke A., Nussbaum C., Kubala L., Friedrichs K., Rudolph T.K., Rudolph V., et al. Myeloperoxidase attracts neutrophils by physical forces. Blood 2011, 117:1350-1358.
14. Lau D., Mollnau H., Eiserich J.P., Freeman B.A., Daiber A., Gehling U.M., et al. Myeloperoxidase mediates neutrophil activation by association with CD11b/CD18 integrins. Proc Natl Acad Sci U S A 2005, 102:431-436.
15. Abu-Soud H.M., Hazen S.L. Nitric oxide modulates the catalytic activity of myeloperoxidase. J Biol Chem 2000, 275:5425-5430.
16. Rudolph T.K., Wipper S., Reiter B., Rudolph V., Coym A., Detter C., et al. Myeloperoxidase deficiency preserves vasomotor function in humans. Eur. Heart J. 2011, 33:1625-1634.
17. Baldus S., Rudolph V., Roiss M., Ito W.D., Rudolph T.K., Eiserich J.P., et al. Heparins increase endothelial nitric oxide bioavailability by liberating vessel-immobilized myeloperoxidase. Circulation 2006, 113:1871-1878.
18. Xu J., Xie Z., Reece R., Pimental D., Zou M.H. Uncoupling of endothelial nitric oxidase synthase by hypochlorous acid: role of NAD(P)H oxidase-derived superoxide and peroxynitrite. Arterioscler Thromb Vasc Biol 2006, 26:2688-2695.
19. von Leitner E.C., Klinke A., Atzler D., Slocum J.L., Lund N., Kielstein J.T., et al. Pathogenic cycle between the endogenous nitric oxide synthase inhibitor asymmetrical dimethylarginine and the leukocyte-derived hemoprotein myeloperoxidase. Circulation 2011, 124:2735-2745.
20. Zhang C., Reiter C., Eiserich J.P., Boersma B., Parks D.A., Beckman J.S., et al. L-arginine chlorination products inhibit endothelial nitric oxide production. J Biol Chem 2001, 276:27159-27165.
21. Yanagisawa M., Kurihara H., Kimura S., Tomobe Y., Kobayashi M., Mitsui Y., et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells 1988.
22. Hassoun P.M., Thappa V., Landman M.J., Fanburg B.L. Endothelin 1: mitogenic activity on pulmonary artery smooth muscle cells and release from hypoxic endothelial cells. Proc Soc Exp Biol Med 1992, 199:165-170.
23. Salani D., Taraboletti G., Rosanò L., Di Castro V., Borsotti P., Giavazzi R., et al. Endothelin-1 induces an angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo. Am J Pathol 2000, 157:1703-1711.
24. Khimji A.K., Rockey D.C. Endothelin-biology and disease. Cell Signal 2010, 22:1615-1625.
25. Böhm F., Pernow J. The importance of endothelin-1 for vascular dysfunction in cardiovascular disease. Cardiovasc Res 2007, 76:8-18.
26. Li J., Cao Y.X., Chen K.L., Cao L., Ma Z., Xu C.B. Regional variations of vasomotion to G-protein coupled receptor agonists following heat stress in rats. J Pharm Pharmacol 2010, 62:315-322.
27. Haynes W.G., Strachan F.E., Webb D.J. Endothelin ETA and ETB receptors cause vasoconstriction of human resistance and capacitance vessels in vivo. Circulation 1995, 92:357-363.
28. Bigaud M., Pelton J.T. Discrimination between ETA- and ETB-receptor-mediated effects of endothelin-1 and [Ala1,3,11,15]endothelin-1 by BQ-123 in the anaesthetized rat. Br J Pharmacol 1992, 107:912-918.
29. Iwasa S., Fan J., Shimokama T., Nagata M., Watanabe T. Increased immunoreactivity of endothelin-1 and endothelin B receptor in human atherosclerotic lesions: a possible role in atherogenesis. Atherosclerosis 1999, 146:93-100.
30. Dagassan P.H., Breu V., Clozel M., Künzli A., Vogt P., Turina M., et al. Up-regulation of endothelin-B receptors in atherosclerotic human coronary arteries. J Cardiovasc Pharmacol 1996, 27:147-153.
31. Wackenfors A., Emilson M., Ingemansson R., Hortobagyi T., Szok D., Tajti J., et al. Ischemic heart disease induce upregulation of endothelin receptor mRNA in human coronary arteries. Eur J Pharmacol 2004, 484:103-109.
32. Nilsson D., Wackenfors A., Gustafsson L., Edvinsson L., Paulsson P., Ingemansson R., et al. Increased ETA and ETB receptor contraction in the left internal mammary artery from patients with hypertension. J Hum Hypertens 2007, 22:226-229.
33. Li J., Cao Y.X., Liu H., Xu C.B. Enhanced G-protein coupled receptors-mediated contraction and reduced endothelium-dependent relaxation in hypertension. Eur J Pharmacol 2007, 557:186-194.
34. Adner M., Cantera L., Ehlert F., Nilsson L., Edvinsson L. Plasticity of contractile endothelin-B receptors in human arteries after organ culture. Br J Pharmacol 1996, 119:1159-1166.
35. Xu C.B., Zheng J.P., Zhang W., Zhang Y., Edvinsson L. Lipid-soluble smoke particles upregulate vascular smooth muscle ETB receptors via activation of mitogen-activating protein kinases and NF-kappaB pathways. Toxicol Sci 2008, 106:546-555.
36. Eiserich J.P., Cross C.E., Jones A.D., Halliwell B., van der Vliet A. Formation of nitrating and chlorinating species by reaction of nitrite with hypochlorous acid: a novel mechanism for nitric oxide-mediated protein modification. J Biol Chem 1996, 271:19199-19208.
37. Eiserich J.P., Hristova M., Cross C.E., Jones A.D., Freeman B.A., Halliwell B., et al. Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils. Nature 1998, 391:393-397.
38. Henderson J.P., Byun J., Williams M.V., Mueller D.M., McCormick M.L., Heinecke J.W. Production of brominating intermediates by myeloperoxidase: a transhalogenation pathway for generating mutagenic nucleobases during inflammation. J Biol Chem 2001, 276:7867-7875.
39. Kettle A.J., Gedye C.A., Winterbourn C.C. Mechanism of inactivation of myeloperoxidase by 4-aminobenzoic acid hydrazide. Biochem J 1997, 321(Pt 2):503-508.
40. Nilsson D., Wackenfors A., Gustafsson L., Ugander M., Paulsson P., Ingemansson R., et al. Endothelin receptor-mediated vasodilatation: effects of organ culture. Eur J Pharmacol 2008, 579:233-240.
41. Uddman E., Henriksson M., Eskesen K., Edvinsson L. Role of mitogen-activated protein kinases in endothelin ETB receptor up-regulation after organ culture of rat mesenteric artery. Eur J Pharmacol 2003, 482:39-47.
42. Stenman E., Malmsjö M., Uddman E., Gidö G., Wieloch T., Edvinsson L. Cerebral ischemia upregulates vascular endothelin ETB receptors in rat. Stroke 2002, 33:2311-2316.