-
1
-
-
0038443099
-
Anti-angiogenic therapy: Rationale, challenges and clinical studies
-
1:CAS:528:DC%2BD3sXltFynsLY%3D 12906317 10.1023/A:1024532022166
-
Longo R, Sarmiento R, Fanelli M, Capaccetti B, Gattuso D, Gasparini G. Anti-angiogenic therapy: rationale, challenges and clinical studies. Angiogenesis. 2002;5(4):237-56.
-
(2002)
Angiogenesis
, vol.5
, Issue.4
, pp. 237-256
-
-
Longo, R.1
Sarmiento, R.2
Fanelli, M.3
Capaccetti, B.4
Gattuso, D.5
Gasparini, G.6
-
2
-
-
0037699955
-
Angiogenesis in health and disease
-
1:CAS:528:DC%2BD3sXktFOntbY%3D 12778163 10.1038/nm0603-653
-
Carmeliet P. Angiogenesis in health and disease. Nat Med. 2003;9(6):653-60.
-
(2003)
Nat Med
, vol.9
, Issue.6
, pp. 653-660
-
-
Carmeliet, P.1
-
3
-
-
10344220521
-
Endogenous angiogenesis inhibitors
-
1:CAS:528:DC%2BD2MXls1Ghtg%3D%3D 15563312 10.1111/j.1600-0463.2004. apm11207-0809.x
-
Folkman J. Endogenous angiogenesis inhibitors. APMIS. 2004;112(7-8):496-507.
-
(2004)
APMIS
, vol.112
, Issue.7-8
, pp. 496-507
-
-
Folkman, J.1
-
5
-
-
32944463899
-
Angiogenesis
-
1:CAS:528:DC%2BD28Xis1Cksrg%3D 16409133 10.1146/annurev.med.57.121304. 131306
-
Folkman J. Angiogenesis. Annu Rev Med. 2006;57:1-18.
-
(2006)
Annu Rev Med
, vol.57
, pp. 1-18
-
-
Folkman, J.1
-
6
-
-
84859266060
-
The possible role of chemotherapy in antiangiogenic drug resistance
-
10.1016/j.mehy.2012.02.001
-
Bocci Gand Loupakis F. The possible role of chemotherapy in antiangiogenic drug resistance. Med Hypotheses. 2012;78(5):646-8.
-
(2012)
Med Hypotheses
, vol.78
, Issue.5
, pp. 646-648
-
-
Bocci Gand Loupakis, F.1
-
7
-
-
0036174289
-
Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: Involvement of vascular endothelial growth factor
-
1:CAS:528:DC%2BD38Xht1equrY%3D 11821896 10.1038/nm0202-128
-
Guba M, von Breitenbuch P, Steinbauer M, Koehl G, Flegel S, Hornung M, et al. Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor. Nat Med. 2002;8(2):128-35.
-
(2002)
Nat Med
, vol.8
, Issue.2
, pp. 128-135
-
-
Guba, M.1
Von Breitenbuch, P.2
Steinbauer, M.3
Koehl, G.4
Flegel, S.5
Hornung, M.6
-
8
-
-
0035865363
-
Redefining the target: Chemotherapeutics as antiangiogenics
-
1:CAS:528:DC%2BD3MXhvFertrY%3D 11181686
-
Miller KD, Sweeney CJ, Sledge Jr GW. Redefining the target: chemotherapeutics as antiangiogenics. J Clin Oncol. 2001;19(4):1195-206.
-
(2001)
J Clin Oncol
, vol.19
, Issue.4
, pp. 1195-1206
-
-
Miller, K.D.1
Sweeney, C.J.2
Sledge, Jr.G.W.3
-
9
-
-
0242331613
-
Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy
-
1:CAS:528:DC%2BD3sXoslKnu7g%3D 240719 14561896 10.1073/pnas.2135406100
-
Bocci G, Francia G, Man S, Lawler J, Kerbel RS. Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy. Proc Natl Acad Sci U S A. 2003;100(22):12917-22.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, Issue.22
, pp. 12917-12922
-
-
Bocci, G.1
Francia, G.2
Man, S.3
Lawler, J.4
Kerbel, R.S.5
-
10
-
-
0036897097
-
Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective antiangiogenic window for various chemotherapeutic drugs
-
1:CAS:528:DC%2BD38XpsVahsLg%3D 12460910
-
Bocci G, Nicolaou KC, Kerbel RS. Protracted low-dose effects on human endothelial cell proliferation and survival in vitro reveal a selective antiangiogenic window for various chemotherapeutic drugs. Cancer Res. 2002;62(23):6938-43.
-
(2002)
Cancer Res
, vol.62
, Issue.23
, pp. 6938-6943
-
-
Bocci, G.1
Nicolaou, K.C.2
Kerbel, R.S.3
-
11
-
-
0036673761
-
In vitro pharmacological characterizations of the anti-angiogenic and anti-tumor cell migration properties mediated by microtubule-affecting drugs, with special emphasis on the organization of the actin cytoskeleton
-
1:CAS:528:DC%2BD38Xmt1Glu7g%3D 12118340
-
Hayot C, Farinelle S, De Decker R, Decaestecker C, Darro F, Kiss R, et al. In vitro pharmacological characterizations of the anti-angiogenic and anti-tumor cell migration properties mediated by microtubule-affecting drugs, with special emphasis on the organization of the actin cytoskeleton. Int J Oncol. 2002;21(2):417-25.
-
(2002)
Int J Oncol
, vol.21
, Issue.2
, pp. 417-425
-
-
Hayot, C.1
Farinelle, S.2
De Decker, R.3
Decaestecker, C.4
Darro, F.5
Kiss, R.6
-
12
-
-
0037268220
-
Paclitaxel at ultra low concentrations inhibits angiogenesis without affecting cellular microtubule assembly
-
12544254 10.1097/00001813-200301000-00003
-
Wang J, Lou P, Lesniewski R, Henkin J. Paclitaxel at ultra low concentrations inhibits angiogenesis without affecting cellular microtubule assembly. Anticancer Drugs. 2003;14(1):13-9.
-
(2003)
Anticancer Drugs
, vol.14
, Issue.1
, pp. 13-19
-
-
Wang, J.1
Lou, P.2
Lesniewski, R.3
Henkin, J.4
-
13
-
-
0036167860
-
Docetaxel versus paclitaxel for antiangiogenesis
-
1:CAS:528:DC%2BD38XhvFOitbs%3D 11847007 10.1089/152581602753448577
-
Vacca A, Ribatti D, Iurlaro M, Merchionne F, Nico B, Ria R, et al. Docetaxel versus paclitaxel for antiangiogenesis. J Hematother Stem Cell Res. 2002;11(1):103-18.
-
(2002)
J Hematother Stem Cell Res
, vol.11
, Issue.1
, pp. 103-118
-
-
Vacca, A.1
Ribatti, D.2
Iurlaro, M.3
Merchionne, F.4
Nico, B.5
Ria, R.6
-
14
-
-
33748047460
-
Taxotere-induced inhibition of human endothelial cell migration is a result of heat shock protein 90 degradation
-
1:CAS:528:DC%2BD28XotFWqtbg%3D 16912198 10.1158/0008-5472.CAN-06-0748
-
Murtagh J, Lu H, Schwartz EL. Taxotere-induced inhibition of human endothelial cell migration is a result of heat shock protein 90 degradation. Cancer Res. 2006;66(16):8192-9.
-
(2006)
Cancer Res
, vol.66
, Issue.16
, pp. 8192-8199
-
-
Murtagh, J.1
Lu, H.2
Schwartz, E.L.3
-
15
-
-
38949145737
-
Antiangiogenic therapy with mammalian target of rapamycin inhibitor RAD001 (Everolimus) increases radiosensitivity in solid cancer
-
1:CAS:528:DC%2BD1cXhsFyktLg%3D 18245553 10.1158/1078-0432.CCR-07-0955
-
Manegold PC, Paringer C, Kulka U, Krimmel K, Eichhorn ME, Wilkowski R, et al. Antiangiogenic therapy with mammalian target of rapamycin inhibitor RAD001 (Everolimus) increases radiosensitivity in solid cancer. Clin Cancer Res. 2008;14(3):892-900.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.3
, pp. 892-900
-
-
Manegold, P.C.1
Paringer, C.2
Kulka, U.3
Krimmel, K.4
Eichhorn, M.E.5
Wilkowski, R.6
-
16
-
-
63449098382
-
MTOR inhibitor RAD001 (everolimus) has antiangiogenic/vascular properties distinct from a VEGFR tyrosine kinase inhibitor
-
1:CAS:528:DC%2BD1MXisVWrsr0%3D 19223496 10.1158/1078-0432.CCR-08-2057
-
Lane HA, Wood JM, McSheehy PM, Allegrini PR, Boulay A, Brueggen J, et al. mTOR inhibitor RAD001 (everolimus) has antiangiogenic/vascular properties distinct from a VEGFR tyrosine kinase inhibitor. Clin Cancer Res. 2009;15(5):1612-22.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.5
, pp. 1612-1622
-
-
Lane, H.A.1
Wood, J.M.2
McSheehy, P.M.3
Allegrini, P.R.4
Boulay, A.5
Brueggen, J.6
-
17
-
-
33746637660
-
Current development of mTOR inhibitors as anticancer agents
-
1:CAS:528:DC%2BD28XnsFCkurk%3D 16883305 10.1038/nrd2062
-
Faivre S, Kroemer G, Raymond E. Current development of mTOR inhibitors as anticancer agents. Nat Rev Drug Discov. 2006;5(8):671-88.
-
(2006)
Nat Rev Drug Discov
, vol.5
, Issue.8
, pp. 671-688
-
-
Faivre, S.1
Kroemer, G.2
Raymond, E.3
-
18
-
-
0038759662
-
Amphiphilic block copolymers for drug delivery
-
1:CAS:528:DC%2BD3sXltlWhu7g%3D 12820139 10.1002/jps.10397
-
Adams ML, Lavasanifar A, Kwon GS. Amphiphilic block copolymers for drug delivery. J Pharm Sci. 2003;92(7):1343-55.
-
(2003)
J Pharm Sci
, vol.92
, Issue.7
, pp. 1343-1355
-
-
Adams, M.L.1
Lavasanifar, A.2
Kwon, G.S.3
-
19
-
-
78651279520
-
Polymeric micelles in anticancer therapy: Targeting, imaging and triggered release
-
1:CAS:528:DC%2BC3cXhtVCmtb3J 2982955 20725771 10.1007/s11095-010-0233-4
-
Oerlemans C, Bult W, Bos M, Storm G, Nijsen JF, Hennink WE. Polymeric micelles in anticancer therapy: targeting, imaging and triggered release. Pharm Res. 2010;27(12):2569-89.
-
(2010)
Pharm Res
, vol.27
, Issue.12
, pp. 2569-2589
-
-
Oerlemans, C.1
Bult, W.2
Bos, M.3
Storm, G.4
Nijsen, J.F.5
Hennink, W.E.6
-
20
-
-
70449711530
-
Multi-drug loaded polymeric micelles for simultaneous delivery of poorly soluble anticancer drugs
-
1:CAS:528:DC%2BD1MXhsVyju7bJ 2787857 19409432 10.1016/j.jconrel.2009.04. 024
-
Shin HC, Alani AW, Rao DA, Rockich NC, Kwon GS. Multi-drug loaded polymeric micelles for simultaneous delivery of poorly soluble anticancer drugs. J Control Release. 2009;140(3):294-300.
-
(2009)
J Control Release
, vol.140
, Issue.3
, pp. 294-300
-
-
Shin, H.C.1
Alani, A.W.2
Rao, D.A.3
Rockich, N.C.4
Kwon, G.S.5
-
21
-
-
79961076052
-
A 3-in-1 polymeric micelle nanocontainer for poorly water-soluble drugs
-
1:CAS:528:DC%2BC3MXnvFSju7Y%3D 21630670 10.1021/mp2000549
-
Shin HC, Alani AW, Cho H, Bae Y, Kolesar JM, Kwon GS. A 3-in-1 polymeric micelle nanocontainer for poorly water-soluble drugs. Mol Pharm. 2011;8(4):1257-65.
-
(2011)
Mol Pharm
, vol.8
, Issue.4
, pp. 1257-1265
-
-
Shin, H.C.1
Alani, A.W.2
Cho, H.3
Bae, Y.4
Kolesar, J.M.5
Kwon, G.S.6
-
22
-
-
84867411762
-
Antitumor activity of Triolimus: A novel multidrug-loaded micelle containing Paclitaxel, Rapamycin, and 17-AAG
-
1:CAS:528:DC%2BC38XhsVyksrrE 3469732 22896668 10.1158/1535-7163.MCT-11- 0987
-
Hasenstein JR, Shin HC, Kasmerchak K, Buehler D, Kwon GS, Kozak KR. Antitumor activity of Triolimus: a novel multidrug-loaded micelle containing Paclitaxel, Rapamycin, and 17-AAG. Mol Cancer Ther. 2012;11(10):2233-42.
-
(2012)
Mol Cancer Ther
, vol.11
, Issue.10
, pp. 2233-2242
-
-
Hasenstein, J.R.1
Shin, H.C.2
Kasmerchak, K.3
Buehler, D.4
Kwon, G.S.5
Kozak, K.R.6
-
23
-
-
80051793564
-
Bivalent sequential binding of docetaxel to methyl-beta-cyclodextrin
-
1:CAS:528:DC%2BC3MXhtVWjt77P 21736931 10.1016/j.ijpharm.2011.06.034
-
Mazzaferro S, Bouchemal K, Gallard JF, Iorga BI, Cheron M, Gueutin C, et al. Bivalent sequential binding of docetaxel to methyl-beta-cyclodextrin. Int J Pharm. 2011;416(1):171-80.
-
(2011)
Int J Pharm
, vol.416
, Issue.1
, pp. 171-180
-
-
Mazzaferro, S.1
Bouchemal, K.2
Gallard, J.F.3
Iorga, B.I.4
Cheron, M.5
Gueutin, C.6
-
24
-
-
84861906379
-
Preparation and in vivo evaluation of liposomal everolimus for lung carcinoma and thyroid carcinoma
-
10.1248/bpb.35.975
-
Iwase Yand Maitani Y. Preparation and in vivo evaluation of liposomal everolimus for lung carcinoma and thyroid carcinoma. Biol Pharm Bull. 2012;35(6):975-9.
-
(2012)
Biol Pharm Bull
, vol.35
, Issue.6
, pp. 975-979
-
-
Iwase Yand Maitani, Y.1
-
25
-
-
80054110603
-
Development of docetaxel-loaded intravenous formulation, Nanoxel-PM using polymer-based delivery system
-
1:CAS:528:DC%2BC3MXhtlWmt7jP 21704664 10.1016/j.jconrel.2011.06.012
-
Lee SW, Yun MH, Jeong SW, In CH, Kim JY, Seo MH, et al. Development of docetaxel-loaded intravenous formulation, Nanoxel-PM using polymer-based delivery system. J Control Release. 2011;155(2):262-71.
-
(2011)
J Control Release
, vol.155
, Issue.2
, pp. 262-271
-
-
Lee, S.W.1
Yun, M.H.2
Jeong, S.W.3
In, C.H.4
Kim, J.Y.5
Seo, M.H.6
-
26
-
-
0020336077
-
Organizational behavior of human umbilical vein endothelial cells
-
1:STN:280:DyaL3s%2FjtV2mug%3D%3D 6813338 10.1083/jcb.94.3.511
-
Maciag T, Kadish J, Wilkins L, Stemerman MB, Weinstein R. Organizational behavior of human umbilical vein endothelial cells. J Cell Biol. 1982;94(3):511-20.
-
(1982)
J Cell Biol
, vol.94
, Issue.3
, pp. 511-520
-
-
Maciag, T.1
Kadish, J.2
Wilkins, L.3
Stemerman, M.B.4
Weinstein, R.5
-
27
-
-
0035044630
-
In vitro models of vasculogenesis and angiogenesis
-
1:CAS:528:DC%2BD3MXjsFSis74%3D 11304563 10.1038/labinvest.3780252
-
Vailhe B, Vittet D, Feige JJ. In vitro models of vasculogenesis and angiogenesis. Lab Investig. 2001;81(4):439-52.
-
(2001)
Lab Investig
, vol.81
, Issue.4
, pp. 439-452
-
-
Vailhe, B.1
Vittet, D.2
Feige, J.J.3
-
28
-
-
0035858296
-
In vivo evaluation of polymeric micellar paclitaxel formulation: Toxicity and efficacy
-
1:CAS:528:DC%2BD3MXktVGks7s%3D 11389998 10.1016/S0168-3659(01)00275-9
-
Kim SC, Kim DW, Shim YH, Bang JS, Oh HS, Wan Kim S, et al. In vivo evaluation of polymeric micellar paclitaxel formulation: toxicity and efficacy. J Control Release. 2001;72(1-3):191-202.
-
(2001)
J Control Release
, vol.72
, Issue.1-3
, pp. 191-202
-
-
Kim, S.C.1
Kim, D.W.2
Shim, Y.H.3
Bang, J.S.4
Oh, H.S.5
Wan Kim, S.6
-
30
-
-
0021118703
-
Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
-
1:CAS:528:DyaL2cXktlaksLk%3D 10.1016/0065-2571(84)90007-4
-
Chou TC, Talalay P. Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv Enzym Regul. 1984;22:27-55.
-
(1984)
Adv Enzym Regul
, vol.22
, pp. 27-55
-
-
Chou, T.C.1
Talalay, P.2
-
31
-
-
84863205849
-
NIH Image to ImageJ: 25 years of image analysis
-
1:CAS:528:DC%2BC38XhtVKntb7P 22930834 10.1038/nmeth.2089
-
Schneider CA, Rasband WS, Eliceiri KW. NIH Image to ImageJ: 25 years of image analysis. Nat Methods. 2012;9(7):671-5.
-
(2012)
Nat Methods
, vol.9
, Issue.7
, pp. 671-675
-
-
Schneider, C.A.1
Rasband, W.S.2
Eliceiri, K.W.3
-
32
-
-
34548436228
-
Targeting microtubules to inhibit angiogenesis and disrupt tumour vasculature: Implications for cancer treatment
-
1:CAS:528:DC%2BD2sXhtV2gtrjF 17896922 10.2174/156800907781662266
-
Pasquier E, Andre N, Braguer D. Targeting microtubules to inhibit angiogenesis and disrupt tumour vasculature: implications for cancer treatment. Curr Cancer Drug Targets. 2007;7(6):566-81.
-
(2007)
Curr Cancer Drug Targets
, vol.7
, Issue.6
, pp. 566-581
-
-
Pasquier, E.1
Andre, N.2
Braguer, D.3
-
33
-
-
84895498069
-
-
(accessed April 21 2013)
-
Pazdur R. FDA approval for doctaxel. http://www.cancer.gov/cancertopics/ druginfo/fda-docetaxel (accessed April 21 2013).
-
FDA Approval for Doctaxel
-
-
Pazdur, R.1
-
34
-
-
80155142474
-
Rapamycin passes the torch: A new generation of mTOR inhibitors
-
1:CAS:528:DC%2BC3MXhtlyis7vI 22037041 10.1038/nrd3531
-
Benjamin D, Colombi M, Moroni C, Hall MN. Rapamycin passes the torch: a new generation of mTOR inhibitors. Nat Rev Drug Discov. 2011;10(11):868-80.
-
(2011)
Nat Rev Drug Discov
, vol.10
, Issue.11
, pp. 868-880
-
-
Benjamin, D.1
Colombi, M.2
Moroni, C.3
Hall, M.N.4
-
35
-
-
84895432817
-
-
(accessed April 21 2013)
-
Pazdur R. FDA Approval for Everolimus. http://www.cancer.gov/ cancertopics/druginfo/fda-everolimus#Anchor-Breast (accessed April 21 2013).
-
FDA Approval for Everolimus
-
-
Pazdur, R.1
-
36
-
-
10044229529
-
Hydrotropic polymer micelle system for delivery of paclitaxel
-
1:CAS:528:DC%2BD2cXhtVKgu7nE 15588894 10.1016/j.jconrel.2004.07.003
-
Huh KM, Lee SC, Cho YW, Lee J, Jeong JH, Park K. Hydrotropic polymer micelle system for delivery of paclitaxel. J Control Release. 2005;101(1-3):59-68.
-
(2005)
J Control Release
, vol.101
, Issue.1-3
, pp. 59-68
-
-
Huh, K.M.1
Lee, S.C.2
Cho, Y.W.3
Lee, J.4
Jeong, J.H.5
Park, K.6
-
37
-
-
0036088478
-
Mechanisms of normal and tumor-derived angiogenesis
-
1:CAS:528:DC%2BD38XjslWltL8%3D 11940508 10.1152/ajpcell.00389.2001
-
Papetti M, Herman IM. Mechanisms of normal and tumor-derived angiogenesis. Am J Physiol Cell Physiol. 2002;282(5):C947-70.
-
(2002)
Am J Physiol Cell Physiol
, vol.282
, Issue.5
, pp. 947-970
-
-
Papetti, M.1
Herman, I.M.2
-
38
-
-
0038105608
-
Inhibition of endothelial cell function in vitro and angiogenesis in vivo by docetaxel (Taxotere): Association with impaired repositioning of the microtubule organizing center
-
1:CAS:528:DC%2BD3sXmvFOgsw%3D%3D 12479700
-
Hotchkiss KA, Ashton AW, Mahmood R, Russell RG, Sparano JA, Schwartz EL. Inhibition of endothelial cell function in vitro and angiogenesis in vivo by docetaxel (Taxotere): association with impaired repositioning of the microtubule organizing center. Mol Cancer Ther. 2002;1(13):1191-200.
-
(2002)
Mol Cancer Ther
, vol.1
, Issue.13
, pp. 1191-1200
-
-
Hotchkiss, K.A.1
Ashton, A.W.2
Mahmood, R.3
Russell, R.G.4
Sparano, J.A.5
Schwartz, E.L.6
-
39
-
-
34249056589
-
A physiologically based pharmacokinetic model of docetaxel disposition: From mouse to man
-
1:CAS:528:DC%2BD2sXkslOhu78%3D 17473210 10.1158/1078-0432.CCR-06-2362
-
Bradshaw-Pierce EL, Eckhardt SG, Gustafson DL. A physiologically based pharmacokinetic model of docetaxel disposition: from mouse to man. Clin Cancer Res. 2007;13(9):2768-76.
-
(2007)
Clin Cancer Res
, vol.13
, Issue.9
, pp. 2768-2776
-
-
Bradshaw-Pierce, E.L.1
Eckhardt, S.G.2
Gustafson, D.L.3
-
40
-
-
0037430246
-
Comparison of antiangiogenic activities using paclitaxel (taxol) and docetaxel (taxotere)
-
1:CAS:528:DC%2BD3sXhtlCgu7c%3D 12532428 10.1002/ijc.10907
-
Grant DS, Williams TL, Zahaczewsky M, Dicker AP. Comparison of antiangiogenic activities using paclitaxel (taxol) and docetaxel (taxotere). Int J Cancer. 2003;104(1):121-9.
-
(2003)
Int J Cancer
, vol.104
, Issue.1
, pp. 121-129
-
-
Grant, D.S.1
Williams, T.L.2
Zahaczewsky, M.3
Dicker, A.P.4
|