High glucose-induced jagged 1 in endothelial cells disturbs notch signaling for angiogenesis: A novel mechanism of diabetic vasculopathy

Journal of Molecular and Cellular Cardiology

Volumn 69, Issue , 2014, Pages 52-66

  Yoon, Chang Hwan ^a,b   Choi, Young Eun ^a   Koh, Seok Jin ^c   Choi, Jae il ^c   Park, Young Bae ^a   Kim, Hyo Soo ^a,c  

^a Seoul National University Hospital   (South Korea)

^b Seoul National University Bundang Hospital   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

Angiogenesis; Cell signaling; Diabetes mellitus; Endothelium; Vascular complications

Indexed keywords

CELL PROTEIN; DELTA LIKE 4; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JAGGED1; LIGAND; MANNITOL; NOTCH RECEPTOR; PROTEIN KINASE C; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; CALCIUM BINDING PROTEIN; MEMBRANE PROTEIN; MESSENGER RNA; SERRATE PROTEINS; SIGNAL PEPTIDE; SWEETENING AGENT;

ARTICLE; BLOOD VESSEL DIAMETER; CELL ACTIVATION; CELL ACTIVITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DIABETIC MICROANGIOPATHY; DIABETIC RETINOPATHY; DOWN REGULATION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MESENCHYME CELL; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RETINA NEOVASCULARIZATION; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; TISSUE GROWTH; ANGIOGENESIS; CELL CULTURE; COCULTURE; CYTOLOGY; DIABETIC ANGIOPATHY; DRUG EFFECTS; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; METABOLISM; MULTICELLULAR SPHEROID; PATHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VASCULAR ENDOTHELIUM; WESTERN BLOTTING;

BLOTTING, WESTERN; CALCIUM-BINDING PROTEINS; CELLS, CULTURED; COCULTURE TECHNIQUES; DIABETIC ANGIOPATHIES; ENDOTHELIUM, VASCULAR; FLUORESCENT ANTIBODY TECHNIQUE; GLUCOSE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MYOCYTES, SMOOTH MUSCLE; NEOVASCULARIZATION, PHYSIOLOGIC; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, NOTCH; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; SPHEROIDS, CELLULAR; SWEETENING AGENTS;

EID: 84895468719     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2013.12.006     Document Type: Article

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