Andrographolide sodium bisulfate-induced apoptosis and autophagy in human proximal tubular endothelial cells is a ROS-mediated pathway

Environmental Toxicology and Pharmacology

Volumn 37, Issue 2, 2014, Pages 718-728

  Lu, Hong ^a   Zhang, Xin Yue ^b   Wang, Yi Qi ^a   Zheng, Xiao Liang ^b   Yin Zhao, ^b   Xing, Wen Min ^a   Zhang, Qin ^a  

^a ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

^b INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Andrographolide sodium bisulfate; Apoptosis; Autophagy; Human proximal tubular endothelial cell; Reactive oxygen species

Indexed keywords

ANDROGRAPHOLIDE; ANDROGRAPHOLIDE SODIUM BISULFATE; BECLIN 1; CASPASE 3; CASPASE 9; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TOXIC SUBSTANCE; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; BAX PROTEIN, HUMAN; BECN1 PROTEIN, HUMAN; CYTOCHROME C; DITERPENE; GLUTATHIONE; MEMBRANE PROTEIN; PROTEIN BAX; PROTEIN BCL 2; SODIUM SULFATE; SULFATE; SUPEROXIDE DISMUTASE;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELL DAMAGE; CELL LEVEL; CELL PROLIFERATION; CELL SURVIVAL; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DOSE RESPONSE; DRUG CYTOTOXICITY; DRUG STRUCTURE; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; KIDNEY TUBULE CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; NEPHROTOXICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; SURVIVAL RATE; CELL LINE; CYTOLOGY; DRUG EFFECTS; ENDOTHELIUM CELL; KIDNEY PROXIMAL TUBULE; METABOLISM; TOXICITY;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASE 9; CELL LINE; CYTOCHROMES C; DITERPENES; ENDOTHELIAL CELLS; GLUTATHIONE; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KIDNEY TUBULES, PROXIMAL; MEMBRANE POTENTIAL, MITOCHONDRIAL; MEMBRANE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; SULFATES; SUPEROXIDE DISMUTASE;

EID: 84895458114     PISSN: 13826689     EISSN: 18727077     Source Type: Journal    
DOI: 10.1016/j.etap.2014.01.019     Document Type: Article

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