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Volumn 42, Issue , 2014, Pages 60-67

Cognitive and biochemical effects of monosodium glutamate and aspartame, administered individually and in combination in male albino mice

Author keywords

Aspartame; Brain neurotransmitters; Brain oxidative stress; Cognitive behavior; Male mice; Monosodium glutamate

Indexed keywords

ASPARTAME; DOPAMINE; DRINKING WATER; GLUTAMATE SODIUM; GLUTATHIONE; LIPID PEROXIDE; SEROTONIN; THIOBARBITURIC ACID REACTIVE SUBSTANCE; 3,4 DIHYDROXYPHENYLACETIC ACID; FLAVORING AGENT; NONNUTRITIVE SWEETENER;

EID: 84895424143     PISSN: 08920362     EISSN: 18729738     Source Type: Journal    
DOI: 10.1016/j.ntt.2014.02.001     Document Type: Article
Times cited : (61)

References (56)
  • 1
    • 84894285943 scopus 로고    scopus 로고
    • Protective effect of curcumin on anxiety, learning behavior, neuromuscular activities, brain neurotransmitters and oxidative stress enzymes in cadmium intoxicated mice
    • Abu-Taweel G.M., Ajarem J.S., Ahmad M. Protective effect of curcumin on anxiety, learning behavior, neuromuscular activities, brain neurotransmitters and oxidative stress enzymes in cadmium intoxicated mice. J Behav Brain Sci 2013, 3:74-84.
    • (2013) J Behav Brain Sci , vol.3 , pp. 74-84
    • Abu-Taweel, G.M.1    Ajarem, J.S.2    Ahmad, M.3
  • 2
    • 0034697213 scopus 로고    scopus 로고
    • Locomotor and learning deficits in adult rats exposed to monosodium-l-glutamate during early life
    • Ali M.M., Bawari U.K., Babu M.G.N. Locomotor and learning deficits in adult rats exposed to monosodium-l-glutamate during early life. Neurosci Lett 2000, 284:57-60.
    • (2000) Neurosci Lett , vol.284 , pp. 57-60
    • Ali, M.M.1    Bawari, U.K.2    Babu, M.G.N.3
  • 3
    • 0027494035 scopus 로고
    • Common food additives are potent inhibitors of human liver 17 alpha-ethinyloestradiol and dopamine sulphotransferases
    • Bamforth K.J., Jones A.L., Roberts R.C., Coughtrie M.W.H. Common food additives are potent inhibitors of human liver 17 alpha-ethinyloestradiol and dopamine sulphotransferases. Biochem Pharmacol 1993, 46:1713-1720.
    • (1993) Biochem Pharmacol , vol.46 , pp. 1713-1720
    • Bamforth, K.J.1    Jones, A.L.2    Roberts, R.C.3    Coughtrie, M.W.H.4
  • 4
    • 82255166294 scopus 로고    scopus 로고
    • Long term effect of monosodium glutamate in liver of albino mice after neo-natal exposure
    • Bhattacharya T., Bhakta A., Ghosh S.K. Long term effect of monosodium glutamate in liver of albino mice after neo-natal exposure. Nepal Med Coll J 2011, 13:11-16.
    • (2011) Nepal Med Coll J , vol.13 , pp. 11-16
    • Bhattacharya, T.1    Bhakta, A.2    Ghosh, S.K.3
  • 5
    • 0018663154 scopus 로고
    • Aspartame: assessment of developmental psychotoxicity of a new artificial sweetener
    • Brunner R.L., Vorhees C.V., Kinney L., Butcher R.E. Aspartame: assessment of developmental psychotoxicity of a new artificial sweetener. Neurobehav Toxicol 1979, 1:79-86.
    • (1979) Neurobehav Toxicol , vol.1 , pp. 79-86
    • Brunner, R.L.1    Vorhees, C.V.2    Kinney, L.3    Butcher, R.E.4
  • 6
    • 74349108947 scopus 로고    scopus 로고
    • Dietary trans-fat combined with monosodium glutamate induces dyslipidemia and impairs spatial memory
    • Collison K.S., Makhoul N.J., Inglis A., Al-Johi M., Zaidi M.Z., Maqbool Z., et al. Dietary trans-fat combined with monosodium glutamate induces dyslipidemia and impairs spatial memory. Physiol Behav 2010, 99:334-342.
    • (2010) Physiol Behav , vol.99 , pp. 334-342
    • Collison, K.S.1    Makhoul, N.J.2    Inglis, A.3    Al-Johi, M.4    Zaidi, M.Z.5    Maqbool, Z.6
  • 7
    • 84862192709 scopus 로고    scopus 로고
    • Interactive effects of neonatal exposure to monosodium glutamate and aspartame on glucose homeostasis
    • Collison K.S., Makhoul N.J., Zaidi M.Z., Al-Rabiah R., Inglis A., Andres B.L., et al. Interactive effects of neonatal exposure to monosodium glutamate and aspartame on glucose homeostasis. Nutr Metab 2012, 9:58-70.
    • (2012) Nutr Metab , vol.9 , pp. 58-70
    • Collison, K.S.1    Makhoul, N.J.2    Zaidi, M.Z.3    Al-Rabiah, R.4    Inglis, A.5    Andres, B.L.6
  • 8
    • 0022618206 scopus 로고
    • Neurobiochemical alterations induced by the artificial sweetener aspartame (NutraSweet)
    • Coulombe R.A., Sharma R.P. Neurobiochemical alterations induced by the artificial sweetener aspartame (NutraSweet). Toxicol Appl Pharmacol 1986, 83:79-85.
    • (1986) Toxicol Appl Pharmacol , vol.83 , pp. 79-85
    • Coulombe, R.A.1    Sharma, R.P.2
  • 9
    • 0021026735 scopus 로고
    • Acute and long lasting neurochemical effects of monosodium glutamate administration to mice
    • Dawson J.R. Acute and long lasting neurochemical effects of monosodium glutamate administration to mice. Neuropharmacology 1983, 22:1417-1419.
    • (1983) Neuropharmacology , vol.22 , pp. 1417-1419
    • Dawson, J.R.1
  • 10
    • 0024406067 scopus 로고
    • Pharmacological analysis of food intake regulation in rats treated neonatally with monosodium l-glutamate (MSG)
    • Dawson J.R., Wallace D.R., Gabriel S.M. Pharmacological analysis of food intake regulation in rats treated neonatally with monosodium l-glutamate (MSG). Pharmacol Biochem Behav 1989, 32:391-398.
    • (1989) Pharmacol Biochem Behav , vol.32 , pp. 391-398
    • Dawson, J.R.1    Wallace, D.R.2    Gabriel, S.M.3
  • 11
    • 0344665686 scopus 로고    scopus 로고
    • Toxicity of hypercaloric diet and monosodium glutamate: oxidative stress and metabolic shifting in hepatic tissue
    • Diniz Y.S., Fernandes A.A.H., Campos K.E., Mani F., Ribas B.O., Novelli E.L.B. Toxicity of hypercaloric diet and monosodium glutamate: oxidative stress and metabolic shifting in hepatic tissue. Food Chem Toxicol 2004, 42:313-319.
    • (2004) Food Chem Toxicol , vol.42 , pp. 313-319
    • Diniz, Y.S.1    Fernandes, A.A.H.2    Campos, K.E.3    Mani, F.4    Ribas, B.O.5    Novelli, E.L.B.6
  • 12
    • 0020530561 scopus 로고
    • Deuterium substitution enhances the effects of β-phenylethylamine on spontaneous motor activity in the rat
    • Dourish C.T., Greenshaw A.J., Boulton A.A. Deuterium substitution enhances the effects of β-phenylethylamine on spontaneous motor activity in the rat. Pharmacol Biochem Behav 1983, 19:471-475.
    • (1983) Pharmacol Biochem Behav , vol.19 , pp. 471-475
    • Dourish, C.T.1    Greenshaw, A.J.2    Boulton, A.A.3
  • 13
    • 0030887441 scopus 로고    scopus 로고
    • Changes of exploratory behaviour and its habituation in rats neonatally treated with monosodium glutamate
    • Dubovicky M., Tokarev D., Skultetyova I., Jeova D. Changes of exploratory behaviour and its habituation in rats neonatally treated with monosodium glutamate. Pharmacol Biochem Behav 1997, 56:565-569.
    • (1997) Pharmacol Biochem Behav , vol.56 , pp. 565-569
    • Dubovicky, M.1    Tokarev, D.2    Skultetyova, I.3    Jeova, D.4
  • 14
    • 0031887574 scopus 로고    scopus 로고
    • Endogenous oxytocin is involved in short-term olfactory memory in female rats
    • Engelmann M., Ebner K., Votjak C.T., Landgraf R. Endogenous oxytocin is involved in short-term olfactory memory in female rats. Behav Brain Res 1998, 90:89-94.
    • (1998) Behav Brain Res , vol.90 , pp. 89-94
    • Engelmann, M.1    Ebner, K.2    Votjak, C.T.3    Landgraf, R.4
  • 15
    • 0037069299 scopus 로고    scopus 로고
    • Beneficial effects of enriched environment following status epilepticus in immature rats
    • Faverjon S., Silveira D.C., Fu D.D., Cha B.H., Akman C., Hu Y., et al. Beneficial effects of enriched environment following status epilepticus in immature rats. Neurology 2002, 59:1356-1364.
    • (2002) Neurology , vol.59 , pp. 1356-1364
    • Faverjon, S.1    Silveira, D.C.2    Fu, D.D.3    Cha, B.H.4    Akman, C.5    Hu, Y.6
  • 16
    • 0025940585 scopus 로고
    • The postweaning housing environment determines expression of learning deficit associated with neonatal monosodium glutamate (M.S.G.)
    • Fisher K.N., Turner R.A., Pineault G., Kleim J., Saari M.H. The postweaning housing environment determines expression of learning deficit associated with neonatal monosodium glutamate (M.S.G.). Neurotoxicol Teratol 1991, 13:507-513.
    • (1991) Neurotoxicol Teratol , vol.13 , pp. 507-513
    • Fisher, K.N.1    Turner, R.A.2    Pineault, G.3    Kleim, J.4    Saari, M.H.5
  • 17
    • 0038504297 scopus 로고    scopus 로고
    • Acute alterations of neurotransmitters leads in striatum of young rats after pilocarpine-induced status epilepticus
    • Freitas R.M., Souza F.C.F., Vasconcelos S.M.M., Viana G.S.B., Fonteles M.M.F. Acute alterations of neurotransmitters leads in striatum of young rats after pilocarpine-induced status epilepticus. Arq Neuropsiquiatr 2003, 61:430-433.
    • (2003) Arq Neuropsiquiatr , vol.61 , pp. 430-433
    • Freitas, R.M.1    Souza, F.C.F.2    Vasconcelos, S.M.M.3    Viana, G.S.B.4    Fonteles, M.M.F.5
  • 18
    • 5644242019 scopus 로고    scopus 로고
    • Monoamines levels after pilocarpine-induced status epilepticus in hippocampus and frontal cortex of Wistar rats
    • Freitas R.M., Vasconcelos S.M.M., Souza F.C.F., Viana G.S.B., Fonteles M.M.F. Monoamines levels after pilocarpine-induced status epilepticus in hippocampus and frontal cortex of Wistar rats. Neurosci Lett 2004, 370:196-200.
    • (2004) Neurosci Lett , vol.370 , pp. 196-200
    • Freitas, R.M.1    Vasconcelos, S.M.M.2    Souza, F.C.F.3    Viana, G.S.B.4    Fonteles, M.M.F.5
  • 19
    • 20444421299 scopus 로고    scopus 로고
    • Behavioral deficits in adult rats treated neonatally with glutamate
    • Hlinak Z., Gandaloviova D., Kreji I. Behavioral deficits in adult rats treated neonatally with glutamate. Neurotoxicol Teratol 2005, 27:465-473.
    • (2005) Neurotoxicol Teratol , vol.27 , pp. 465-473
    • Hlinak, Z.1    Gandaloviova, D.2    Kreji, I.3
  • 20
    • 0024592723 scopus 로고
    • Behavioral assessment of the toxicity of aspartame
    • Holder M.D., Yirmiya R. Behavioral assessment of the toxicity of aspartame. Pharmacol Biochem Behav 1989, 32:17-26.
    • (1989) Pharmacol Biochem Behav , vol.32 , pp. 17-26
    • Holder, M.D.1    Yirmiya, R.2
  • 21
    • 0023876182 scopus 로고
    • Aspartame: review of recent experimental and observational data
    • Janssen P.J.C.M., van der Heijdan C.A. Aspartame: review of recent experimental and observational data. Toxicology 1988, 50:1-26.
    • (1988) Toxicology , vol.50 , pp. 1-26
    • Janssen, P.J.C.M.1    van der Heijdan, C.A.2
  • 22
    • 0034979352 scopus 로고    scopus 로고
    • Cognitive performances and locomotor activity following dentate granule cell damage in rats: role of lesion extent and type of memory tested
    • Jeltsch H., Bertrand F., Lazarus C., Cassel J.C. Cognitive performances and locomotor activity following dentate granule cell damage in rats: role of lesion extent and type of memory tested. Neurobiol Learn Mem 2001, 76:81-105.
    • (2001) Neurobiol Learn Mem , vol.76 , pp. 81-105
    • Jeltsch, H.1    Bertrand, F.2    Lazarus, C.3    Cassel, J.C.4
  • 23
    • 0021675283 scopus 로고
    • Effects of neonatal monosodium glutamate (MSG) treatment on the hormonal and central monoaminergic dynamics associated with acute ether stress in the male rat
    • Johnston C.A., Spinedi E.J., Negro-Vilar A. Effects of neonatal monosodium glutamate (MSG) treatment on the hormonal and central monoaminergic dynamics associated with acute ether stress in the male rat. Brain Res Bull 1984, 13:643-649.
    • (1984) Brain Res Bull , vol.13 , pp. 643-649
    • Johnston, C.A.1    Spinedi, E.J.2    Negro-Vilar, A.3
  • 24
    • 1842300144 scopus 로고
    • Methods used in safety evaluation
    • Marcel Dekker, Inc., New York, A.L. Branen, P.M. Davidson, S. Salminen (Eds.)
    • Kokoski C.J., Henry S.H., Lin C.S., Ekelman K.B. Methods used in safety evaluation. Food additives 1990, 579-616. Marcel Dekker, Inc., New York. A.L. Branen, P.M. Davidson, S. Salminen (Eds.).
    • (1990) Food additives , pp. 579-616
    • Kokoski, C.J.1    Henry, S.H.2    Lin, C.S.3    Ekelman, K.B.4
  • 25
    • 0017282850 scopus 로고
    • The effects of neonatally-administered monosodium glutamate on the reproductive system of adult hamsters
    • Lamperti A., Blaha G. The effects of neonatally-administered monosodium glutamate on the reproductive system of adult hamsters. Biol Reprod 1978, 14:362-369.
    • (1978) Biol Reprod , vol.14 , pp. 362-369
    • Lamperti, A.1    Blaha, G.2
  • 26
    • 0026552463 scopus 로고
    • Pharmacokinetic data in the evaluation of the safety of food and color additives
    • Lin C.S., Shoaf S.E., Griffiths J.C. Pharmacokinetic data in the evaluation of the safety of food and color additives. Regul Toxicol Pharmacol 1992, 15:62-72.
    • (1992) Regul Toxicol Pharmacol , vol.15 , pp. 62-72
    • Lin, C.S.1    Shoaf, S.E.2    Griffiths, J.C.3
  • 27
    • 0022853586 scopus 로고
    • Behavioral and endocrinological effects of single injections of monosodium glutamate in the mouse
    • Lorden J.F., Caudale A. Behavioral and endocrinological effects of single injections of monosodium glutamate in the mouse. Neurobehav Toxicol Teratol 1986, 8:509-519.
    • (1986) Neurobehav Toxicol Teratol , vol.8 , pp. 509-519
    • Lorden, J.F.1    Caudale, A.2
  • 28
    • 0026327659 scopus 로고
    • Protective effects of glycine during hypothermic renal ischemic reperfusion injury
    • Mangino M.J., Murphy M.K., Glabar G.G. Protective effects of glycine during hypothermic renal ischemic reperfusion injury. Am J Physiol 1991, 261:F841-F848.
    • (1991) Am J Physiol , vol.261
    • Mangino, M.J.1    Murphy, M.K.2    Glabar, G.G.3
  • 29
    • 17044448363 scopus 로고
    • Effect of aluminum on the non-enzymatic oxidation of dopamine
    • Marinho C.R., Manso C.F. Effect of aluminum on the non-enzymatic oxidation of dopamine. Acta Med Port 1994, 7:611-615.
    • (1994) Acta Med Port , vol.7 , pp. 611-615
    • Marinho, C.R.1    Manso, C.F.2
  • 30
    • 0033581353 scopus 로고    scopus 로고
    • Neonatal monosodium glutamate alters circadian organization of feeding, food anticipatory activity and photic masking in the rat
    • Mistlberger R.E., Antle M.C. Neonatal monosodium glutamate alters circadian organization of feeding, food anticipatory activity and photic masking in the rat. Brain Res 1999, 842:73-83.
    • (1999) Brain Res , vol.842 , pp. 73-83
    • Mistlberger, R.E.1    Antle, M.C.2
  • 31
    • 0024353737 scopus 로고
    • The effect of neuropeptide Y on drinking in mice
    • Morley J.E., Flood J.F. The effect of neuropeptide Y on drinking in mice. Brain Res 1989, 494:129-137.
    • (1989) Brain Res , vol.494 , pp. 129-137
    • Morley, J.E.1    Flood, J.F.2
  • 32
    • 0021173996 scopus 로고
    • Developments of a water-maze procedure for studying spatial learning in the rat
    • Morris R.G.M. Developments of a water-maze procedure for studying spatial learning in the rat. J Neurosci Methods 1984, 11:47-60.
    • (1984) J Neurosci Methods , vol.11 , pp. 47-60
    • Morris, R.G.M.1
  • 33
    • 0015981903 scopus 로고
    • Irreversible inhibition of pituitary prolactin and growth hormone secretion and of mammary gland development in mice by monosodium glutamate administered neonatally
    • Nagasawa H., Yanai R., Kikuyama S. Irreversible inhibition of pituitary prolactin and growth hormone secretion and of mammary gland development in mice by monosodium glutamate administered neonatally. Acta Endocrinol 1974, 75:249-259.
    • (1974) Acta Endocrinol , vol.75 , pp. 249-259
    • Nagasawa, H.1    Yanai, R.2    Kikuyama, S.3
  • 34
    • 0034305638 scopus 로고    scopus 로고
    • Effects of chronic administration of sibutramine on body weight, food intake and motor activity in neonatally monosodium glutamate-treated obese female rats: relationship of antiobesity effect with monoamines
    • Nakagawa T., Ukai K., Ohyama T., Gomita Y., Okamura H. Effects of chronic administration of sibutramine on body weight, food intake and motor activity in neonatally monosodium glutamate-treated obese female rats: relationship of antiobesity effect with monoamines. Exp Anim 2000, 49:239-249.
    • (2000) Exp Anim , vol.49 , pp. 239-249
    • Nakagawa, T.1    Ukai, K.2    Ohyama, T.3    Gomita, Y.4    Okamura, H.5
  • 35
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Ohkawa H., Ohishi N., Tgi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Ann Chem 1979, 95:351-358.
    • (1979) Ann Chem , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Tgi, K.3
  • 36
    • 0014937190 scopus 로고
    • Brain damage in infant mice following oral intake of glutamate, aspartate or cysteine
    • Olney J.W., Ho O.L. Brain damage in infant mice following oral intake of glutamate, aspartate or cysteine. Nature 1970, 27:609-611.
    • (1970) Nature , vol.27 , pp. 609-611
    • Olney, J.W.1    Ho, O.L.2
  • 37
    • 0019202311 scopus 로고
    • Brain damage in mice from voluntary ingestion of glutamate and aspartate
    • Olney J.W., Labruyere J., de Gubareff T. Brain damage in mice from voluntary ingestion of glutamate and aspartate. Neurobehav Toxicol 1980, 2:125-129.
    • (1980) Neurobehav Toxicol , vol.2 , pp. 125-129
    • Olney, J.W.1    Labruyere, J.2    de Gubareff, T.3
  • 39
    • 33644929220 scopus 로고    scopus 로고
    • Monosodium glutamate induced damage in liver and kidney; a morphological and biochemical approach
    • Ortiz G.G., Bitzer-Quintero O.K., Zarate C.B. Monosodium glutamate induced damage in liver and kidney; a morphological and biochemical approach. Biomed Pharmacother 2006, 50:86-91.
    • (2006) Biomed Pharmacother , vol.50 , pp. 86-91
    • Ortiz, G.G.1    Bitzer-Quintero, O.K.2    Zarate, C.B.3
  • 40
    • 0342313567 scopus 로고    scopus 로고
    • Glutamate and aspartate impair memory retention and damage hypothalamic neurons in adult mice
    • Park C.H., Choi S.H., Piao Y., Kim S., Lee Y., Kim H., et al. Glutamate and aspartate impair memory retention and damage hypothalamic neurons in adult mice. Toxicol Lett 2000, 115:117-125.
    • (2000) Toxicol Lett , vol.115 , pp. 117-125
    • Park, C.H.1    Choi, S.H.2    Piao, Y.3    Kim, S.4    Lee, Y.5    Kim, H.6
  • 41
    • 0026084720 scopus 로고
    • Central nervous system bioaminergic responses to mechanical trauma. An experimental study
    • Patrick O.E., Hirohisa M., Masahira K., Koreaki M. Central nervous system bioaminergic responses to mechanical trauma. An experimental study. Surg Neurol 1991, 35:273-279.
    • (1991) Surg Neurol , vol.35 , pp. 273-279
    • Patrick, O.E.1    Hirohisa, M.2    Masahira, K.3    Koreaki, M.4
  • 42
    • 0017367151 scopus 로고
    • Monosodium glutamate administration to the newborn reduces reproductive ability in female and male mice
    • Pizzi W.J., Barnhart J.E., Fanslow D.J. Monosodium glutamate administration to the newborn reduces reproductive ability in female and male mice. Science 1978, 196:452-454.
    • (1978) Science , vol.196 , pp. 452-454
    • Pizzi, W.J.1    Barnhart, J.E.2    Fanslow, D.J.3
  • 43
    • 0017055661 scopus 로고
    • Hypothalamic morphology following ingestion of aspartame or MSG in the neonatal rodent and primate: a preliminary report
    • Reynolds W.A., Butler V., Lemkey-Johnston N. Hypothalamic morphology following ingestion of aspartame or MSG in the neonatal rodent and primate: a preliminary report. J Toxicol Environ Health 1976, 2:471-480.
    • (1976) J Toxicol Environ Health , vol.2 , pp. 471-480
    • Reynolds, W.A.1    Butler, V.2    Lemkey-Johnston, N.3
  • 44
    • 0016086279 scopus 로고
    • Age dependent sensitivity to monosodium glutamate inducing brain damage in the chicken
    • Robinzon B., Snapir N., Perek M. Age dependent sensitivity to monosodium glutamate inducing brain damage in the chicken. Poult Sci 1974, 54:1539-1542.
    • (1974) Poult Sci , vol.54 , pp. 1539-1542
    • Robinzon, B.1    Snapir, N.2    Perek, M.3
  • 45
    • 0036460079 scopus 로고    scopus 로고
    • Memory impairment following status epilepticus in immature rats: time-course and environmental effects
    • Rutten A., van Albada M., Silveira D.C., Cha B.H., Liu X., Hu Y.N., et al. Memory impairment following status epilepticus in immature rats: time-course and environmental effects. Eur J Neurosci 2002, 16:501-513.
    • (2002) Eur J Neurosci , vol.16 , pp. 501-513
    • Rutten, A.1    van Albada, M.2    Silveira, D.C.3    Cha, B.H.4    Liu, X.5    Hu, Y.N.6
  • 47
    • 0028213751 scopus 로고
    • Serotonin protects C6 glioma cells from glutamate toxicity
    • Shinagawa S. Serotonin protects C6 glioma cells from glutamate toxicity. Neuroscience 1994, 59:1043-1050.
    • (1994) Neuroscience , vol.59 , pp. 1043-1050
    • Shinagawa, S.1
  • 48
    • 0035689519 scopus 로고    scopus 로고
    • Bilateral hippocampal pathology impairs topographical band episodic memory but not visual pattern matching
    • Spiers H.J., Burgess N., Hartley T., Vargha-Khadem F., O'Keefe J. Bilateral hippocampal pathology impairs topographical band episodic memory but not visual pattern matching. Hippocampus 2001, 11:715-725.
    • (2001) Hippocampus , vol.11 , pp. 715-725
    • Spiers, H.J.1    Burgess, N.2    Hartley, T.3    Vargha-Khadem, F.4    O'Keefe, J.5
  • 49
    • 0023375561 scopus 로고
    • The aspartame story: a model for the clinical testing of a food additive
    • Stegink L.D. The aspartame story: a model for the clinical testing of a food additive. Am J Clin Nutr 1987, 46:204-215.
    • (1987) Am J Clin Nutr , vol.46 , pp. 204-215
    • Stegink, L.D.1
  • 50
    • 0020365641 scopus 로고
    • Effect of aspartame plus monosodium l-glutamate ingestion on plasma and erythrocyte amino acid levels in normal adult subjects fed a high protein meal
    • Stegink L.D., Filler L.J., Baber G.L. Effect of aspartame plus monosodium l-glutamate ingestion on plasma and erythrocyte amino acid levels in normal adult subjects fed a high protein meal. Am J Clin Nutr 1982, 36:1145-1152.
    • (1982) Am J Clin Nutr , vol.36 , pp. 1145-1152
    • Stegink, L.D.1    Filler, L.J.2    Baber, G.L.3
  • 51
    • 0022389262 scopus 로고
    • Plasma glutamate concentrations in adult subjects ingesting monosodium l-glutamate in consomme
    • Stegink L.D., Filer L.J., Baker G.L. Plasma glutamate concentrations in adult subjects ingesting monosodium l-glutamate in consomme. Am J Clin Nutr 1985, 42:220-225.
    • (1985) Am J Clin Nutr , vol.42 , pp. 220-225
    • Stegink, L.D.1    Filer, L.J.2    Baker, G.L.3
  • 52
    • 40849126613 scopus 로고    scopus 로고
    • Pentoxifylline ameliorates lithium-pilocarpine induced status epilepticus in young rats
    • Tariq M., Ahmad M., Al Moutaery K., Al Deeb S. Pentoxifylline ameliorates lithium-pilocarpine induced status epilepticus in young rats. Epilepsy Behav 2008, 12:354-365.
    • (2008) Epilepsy Behav , vol.12 , pp. 354-365
    • Tariq, M.1    Ahmad, M.2    Al Moutaery, K.3    Al, D.S.4
  • 53
    • 0030964847 scopus 로고    scopus 로고
    • Deficits in water escape performance and alterations in hippocampal cholinergic mechanisms associated with neonatal monosodium glutamate treatment in mice
    • Wong P.T.H., Neo L.H., Teo W.L., Feng H., Xue Y.D., Loke W.H. Deficits in water escape performance and alterations in hippocampal cholinergic mechanisms associated with neonatal monosodium glutamate treatment in mice. Pharmacol Biochem Behav 1997, 57:383-388.
    • (1997) Pharmacol Biochem Behav , vol.57 , pp. 383-388
    • Wong, P.T.H.1    Neo, L.H.2    Teo, W.L.3    Feng, H.4    Xue, Y.D.5    Loke, W.H.6
  • 54
    • 18144406494 scopus 로고    scopus 로고
    • The roles of metallothionein on cadmium-induced testes damages in Sprague-Dawley rats
    • Xu L.C., Sun H., Wang S.Y., Song L., Chang H.C., Wang X.R. The roles of metallothionein on cadmium-induced testes damages in Sprague-Dawley rats. Environ Toxicol Pharmacol 2005, 20:83-87.
    • (2005) Environ Toxicol Pharmacol , vol.20 , pp. 83-87
    • Xu, L.C.1    Sun, H.2    Wang, S.Y.3    Song, L.4    Chang, H.C.5    Wang, X.R.6
  • 55
    • 0031058402 scopus 로고    scopus 로고
    • Effects of maternal oral administration of monosodium glutamate at late stage of pregnancy on development of mouse fetal brain
    • Yu T., Zhao Y., Shi W., Ma R., Yu L. Effects of maternal oral administration of monosodium glutamate at late stage of pregnancy on development of mouse fetal brain. Brain Res 1997, 747:195-206.
    • (1997) Brain Res , vol.747 , pp. 195-206
    • Yu, T.1    Zhao, Y.2    Shi, W.3    Ma, R.4    Yu, L.5
  • 56
    • 0032562413 scopus 로고    scopus 로고
    • Monosodium glutamate lesions inhibit the N-methyl-aspartate-induced growth hormone but not prolactin release in rats
    • Zelena D., Jezova D., Acs Z., Makara G.B. Monosodium glutamate lesions inhibit the N-methyl-aspartate-induced growth hormone but not prolactin release in rats. Life Sci 1998, 62:2065-2072.
    • (1998) Life Sci , vol.62 , pp. 2065-2072
    • Zelena, D.1    Jezova, D.2    Acs, Z.3    Makara, G.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.