Mutated calreticulin retains structurally disordered C terminus that cannot bind Ca2+: Some mechanistic and therapeutic implications

Blood Cancer Journal

Volumn 4, Issue 2, 2014, Pages

  Shivarov, V ^a   Ivanova, M ^b   Tiu, R V ^c  

^a National Hematology Hospital   (Bulgaria)

^b UNIVERSITY HOSPITAL ALEXANDROVSKA   (Bulgaria)

^c TAUSSIG CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CALCINEURIN; CALCIUM ION; CALRETICULIN; CHAPERONE; GLUTAMIC ACID; JANUS KINASE 2; MUTANT PROTEIN;

BINDING AFFINITY; CALCIUM BINDING; CALCIUM DEPLETION; CARBOXY TERMINAL SEQUENCE; CELL FUNCTION; DELETION MUTANT; ENDOPLASMIC RETICULUM; ERYTHROID PRECURSOR CELL; GENE MUTATION; ISOELECTRIC POINT; KNOCKOUT MOUSE; LETTER; MEGAKARYOCYTE; MEGAKARYOPOIESIS; MYELOPROLIFERATIVE NEOPLASM; NONHUMAN; OPEN READING FRAME; SOMATIC MUTATION; THROMBOCYTHEMIA; VIRUS ONCOGENE;

EID: 84895420327     PISSN: None     EISSN: 20445385     Source Type: Journal    
DOI: 10.1038/bcj.2014.7     Document Type: Letter

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